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Check availability on Midtown Business Hotels

Tonight
22 Dec - 23 Dec
Tomorrow
23 Dec - 24 Dec
This weekend
26 Dec - 28 Dec
Next weekend
2 Jan - 4 Jan

Our top choices for Midtown business-friendly hotels

Exterior
La Maison in Midtown an urban B&B

La Maison in Midtown an urban B&B

La Maison in Midtown an urban B&B
3.5 star property
Midtown
9.8 out of 10, Exceptional, (542)
"great neighborhood, friendly staff, and delicious breakfast"
United States
Anna
The price is 4.710.385 ₫
5.511.150 ₫ total
includes taxes & fees
23 Dec - 24 Dec
La Maison in Midtown an urban B&B
Lobby
Club Quarters Hotel Downtown, Houston

Club Quarters Hotel Downtown, Houston

Club Quarters Hotel Downtown, Houston
4.0 star property
Downtown Houston
8.4 out of 10, Very good, (3966)
"Rooms were great and the staff was absolutely amazing. "
United States
Elmer
The price is 2.091.250 ₫
2.446.761 ₫ total
includes taxes & fees
27 Dec - 28 Dec
Club Quarters Hotel Downtown, Houston
Interior
Best Western Plus Pearland/Houston Medical Center Hotel

Best Western Plus Pearland/Houston Medical Center Hotel

Best Western Plus Pearland/Houston Medical Center Hotel
2.5 star property
Southeast Houston
9.4 out of 10, Exceptional, (58)
"Very nice and clean staff was great!!! Will vist again if im in that area "
United States
Roderick
The price is 2.108.095 ₫
2.466.471 ₫ total
includes taxes & fees
1 Jan - 2 Jan 2026
Best Western Plus Pearland/Houston Medical Center Hotel
Property amenity
TownePlace Suites by Marriott Humble Intercontinental Airport

TownePlace Suites by Marriott Humble Intercontinental Airport

TownePlace Suites by Marriott Humble Intercontinental Airport
2.5 star property
Humble
9.6 out of 10, Exceptional, (96)
"very nice hotel"
United States
Bernardo
The price is 2.657.815 ₫
3.123.598 ₫ total
includes taxes & fees
26 Dec - 27 Dec
TownePlace Suites by Marriott Humble Intercontinental Airport
Exterior
The Royal Sonesta Houston Galleria

The Royal Sonesta Houston Galleria

The Royal Sonesta Houston Galleria
4.0 star property
The Galleria
8.4 out of 10, Very good, (1477)
"Wonderful hotel!"
United States
Debbie
The price is 2.925.934 ₫
3.423.342 ₫ total
includes taxes & fees
27 Dec - 28 Dec
The Royal Sonesta Houston Galleria
Sun deck
Hilton Houston Plaza/Medical Center

Hilton Houston Plaza/Medical Center

Hilton Houston Plaza/Medical Center
4.5 star property
Texas Medical Center
8.4 out of 10, Very good, (1782)
"Clean rooms, comfortable bed, & friendly staff"
United States
Thomas
The price is 2.299.931 ₫
2.721.445 ₫ total
includes taxes & fees
3 Jan - 4 Jan 2026
Hilton Houston Plaza/Medical Center
View from property
Magnolia Hotel Houston, A Tribute Portfolio Hotel

Magnolia Hotel Houston, A Tribute Portfolio Hotel

Magnolia Hotel Houston, A Tribute Portfolio Hotel
4.0 star property
Downtown Houston
9.2 out of 10, Wonderful, (1350)
"Bed was very nice and comfortable! "
United States
Luis
The price is 2.960.437 ₫
3.545.288 ₫ total
includes taxes & fees
24 Dec - 25 Dec
Magnolia Hotel Houston, A Tribute Portfolio Hotel
Terrace/patio
Courtyard by Marriott Houston Intercontinental Airport

Courtyard by Marriott Houston Intercontinental Airport

Courtyard by Marriott Houston Intercontinental Airport
3.0 star property
Houston
9.0 out of 10, Wonderful, (1086)
"Courteous staff, clean rooms, excellent location."
United States
Rebecca
The price is 2.438.085 ₫
2.852.559 ₫ total
includes taxes & fees
27 Dec - 28 Dec
Courtyard by Marriott Houston Intercontinental Airport
Lobby
Blossom Hotel Houston, Curio Collection by Hilton

Blossom Hotel Houston, Curio Collection by Hilton

Blossom Hotel Houston, Curio Collection by Hilton
4.0 star property
Texas Medical Center
9.0 out of 10, Wonderful, (3616)
"Cute hotel, very clean and friendly staff. We enjoyed our stay!"
United States
Alison
The price is 3.430.950 ₫
4.014.211 ₫ total
includes taxes & fees
18 Jan - 19 Jan 2026
Blossom Hotel Houston, Curio Collection by Hilton
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Midtown Hotel Reviews

Heritage Place Houston Brookhollow

Heritage Place Houston Brookhollow

10/10 Excellent
"Bed was comfortable, staff friendly, gas station beside the hotel and restaurant across from the hotel all in walking distance."
Jenna 4-night trip
Posted 3 days ago
Heritage Place Houston Brookhollow

Frequently asked questions

Why book your business-friendly hotel in Midtown with Expedia?
With handy amenities like meeting rooms, housekeeping and free WiFi, our business-friendly accommodation come with all you'll need to get the job done — and then unwind! Enter your preferred travel dates and destination and we'll help you with the rest.
How can I find cheap business-friendly hotels in Midtown?
Select the "business friendly" filter, located just under the "traveller experience" heading, to find cheap business-friendly hotels in Midtown. Then fine-tune your search by your preferred hotel star rating and budget. Basing yourself outside the city centre can also help you save.