Search Hotels in Mira Mesa, San Diego

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19 Dec - 20 Dec
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20 Dec - 21 Dec
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Our top choices for Mira Mesa hotels

3 outdoor pools, pool cabanas (surcharge), pool umbrellas
Sycuan Casino Resort

Sycuan Casino Resort

Sycuan Casino Resort
4.0 star property
32.8 km from Mira Mesa
9.2 out of 10, Wonderful, (1628)
"Very peaceful resort "
United States
Camilla
Sycuan Casino Resort
Premium bedding, pillow-top beds, desk, laptop workspace
Staypineapple, Hotel Z, Gaslamp San Diego

Staypineapple, Hotel Z, Gaslamp San Diego

Staypineapple, Hotel Z, Gaslamp San Diego
3.0 star property
Gaslamp Quarter, 22.8 km from Mira Mesa
9.4 out of 10, Exceptional, (1001)
"Great location "
United States
Mohammad
The price is 2.344.666 ₫
3.479.028 ₫ total
includes taxes & fees
5 Jan - 6 Jan 2026
Staypineapple, Hotel Z, Gaslamp San Diego
Courtyard
Holiday Inn Carlsbad by IHG

Holiday Inn Carlsbad by IHG

Holiday Inn Carlsbad by IHG
3.0 star property
26.1 km from Mira Mesa
9.0 out of 10, Wonderful, (1001)
"Great accommodations!!"
United States
Mark
The price is 2.552.555 ₫
2.863.839 ₫ total
includes taxes & fees
4 Jan - 5 Jan 2026
Holiday Inn Carlsbad by IHG
Exterior
Comfort Inn San Diego Old Town

Comfort Inn San Diego Old Town

Comfort Inn San Diego Old Town
2.5 star property
Old Town San Diego, 19.1 km from Mira Mesa
8.2 out of 10, Very good, (1914)
"Great stay "
United States
Vanessa
The price is 1.999.940 ₫
2.298.830 ₫ total
includes taxes & fees
4 Jan - 5 Jan 2026
Comfort Inn San Diego Old Town
Standard Room, 1 King Bed, Non Smoking, Bay View | Premium bedding, pillow-top beds, in-room safe, desk
The DEXTRO Little Italy, BW Premier Collection

The DEXTRO Little Italy, BW Premier Collection

The DEXTRO Little Italy, BW Premier Collection
3.0 star property
21.6 km from Mira Mesa
8.8 out of 10, Excellent, (761)
"Friendly staff and clean rooms. "
Canada
Justine
The price is 2.885.663 ₫
3.345.781 ₫ total
includes taxes & fees
21 Dec - 22 Dec
The DEXTRO Little Italy, BW Premier Collection
Courtyard
Leucadia Beach Inn

Leucadia Beach Inn

Leucadia Beach Inn
2.5 star property
22.9 km from Mira Mesa
9.4 out of 10, Exceptional, (1004)
"Love this place!"
United States
BILL
The price is 2.344.666 ₫
2.579.132 ₫ total
includes taxes & fees
8 Jan - 9 Jan 2026
Leucadia Beach Inn
Outdoor pool
West Inn & Suites

West Inn & Suites

West Inn & Suites
3.5 star property
30.1 km from Mira Mesa
9.4 out of 10, Exceptional, (1085)
"Great place!"
United States
Adam
The price is 3.401.740 ₫
4.407.064 ₫ total
includes taxes & fees
21 Dec - 22 Dec
West Inn & Suites
Room, 1 King Bed with Sofa bed, Marina View | View from room
Sheraton San Diego Resort

Sheraton San Diego Resort

Sheraton San Diego Resort
4.0 star property
21.5 km from Mira Mesa
8.4 out of 10, Very good, (3168)
"Great stay! "
United States
Melissa
The price is 2.795.969 ₫
4.161.167 ₫ total
includes taxes & fees
4 Jan - 5 Jan 2026
Sheraton San Diego Resort
Exterior
Hampton Inn Carlsbad-North San Diego County

Hampton Inn Carlsbad-North San Diego County

Hampton Inn Carlsbad-North San Diego County
2.5 star property
26.3 km from Mira Mesa
9.2 out of 10, Wonderful, (1004)
"Hotel was clean, staff friendly, breakfast had a great variety and food was delicious!"
United States
Christina
The price is 2.826.757 ₫
3.194.236 ₫ total
includes taxes & fees
11 Jan - 12 Jan 2026
Hampton Inn Carlsbad-North San Diego County
Lobby
Fairfield Inn & Suites by Marriott San Diego Pacific Beach

Fairfield Inn & Suites by Marriott San Diego Pacific Beach

Fairfield Inn & Suites by Marriott San Diego Pacific Beach
2.5 star property
Pacific Beach, 14.3 km from Mira Mesa
9.0 out of 10, Wonderful, (807)
"good place to stay"
United States
Sisi
The price is 2.710.445 ₫
3.115.521 ₫ total
includes taxes & fees
30 Dec - 31 Dec
Fairfield Inn & Suites by Marriott San Diego Pacific Beach
Reception
Best Western Plus Island Palms Hotel & Marina

Best Western Plus Island Palms Hotel & Marina

Best Western Plus Island Palms Hotel & Marina
3.0 star property
23.8 km from Mira Mesa
8.8 out of 10, Excellent, (1555)
"Staff was great, easy check in and great location"
United States
Alysa
The price is 2.926.228 ₫
3.363.553 ₫ total
includes taxes & fees
5 Jan - 6 Jan 2026
Best Western Plus Island Palms Hotel & Marina
Reception
Kings Inn San Diego

Kings Inn San Diego

Kings Inn San Diego
2.5 star property
17.7 km from Mira Mesa
8.8 out of 10, Excellent, (3573)
"Room was very clean, and the breakfast was good"
United States
Roxana
Kings Inn San Diego
Courtyard
DoubleTree by Hilton San Diego - Del Mar

DoubleTree by Hilton San Diego - Del Mar

DoubleTree by Hilton San Diego - Del Mar
4.0 star property
Carmel Valley, 9 km from Mira Mesa
8.4 out of 10, Very good, (1901)
"Excellent location"
United States
Paolo
The price is 2.583.080 ₫
2.943.290 ₫ total
includes taxes & fees
4 Jan - 5 Jan 2026
DoubleTree by Hilton San Diego - Del Mar
Lobby
Wyndham Garden San Diego Near SeaWorld

Wyndham Garden San Diego Near SeaWorld

Wyndham Garden San Diego Near SeaWorld
3.0 star property
19.1 km from Mira Mesa
7.4 out of 10, Good, (4110)
"Room was very clean and staff very pleasant "
Canada
Brian
The price is 2.342.035 ₫
2.692.052 ₫ total
includes taxes & fees
21 Dec - 22 Dec
Wyndham Garden San Diego Near SeaWorld
Outdoor pool, open 7:00 AM to 10:00 PM, pool cabanas (surcharge)
San Diego Mission Bay Resort

San Diego Mission Bay Resort

San Diego Mission Bay Resort
4.0 star property
Mission Bay, 16.4 km from Mira Mesa
8.4 out of 10, Very good, (1310)
"Room was super clean and updated, location up against the bay was perfect. We really enjoyed our stay and want to come back soon!"
United States
Haley
The price is 3.875.147 ₫
5.640.883 ₫ total
includes taxes & fees
3 Jan - 4 Jan 2026
San Diego Mission Bay Resort
2 outdoor pools, open 6 AM to 10:00 PM, pool cabanas (surcharge)
Marriott Marquis San Diego Marina

Marriott Marquis San Diego Marina

Marriott Marquis San Diego Marina
4.0 star property
Marina District, 23 km from Mira Mesa
9.2 out of 10, Wonderful, (1950)
"Amazing hotel Superb view Friendly staff Clean and neat rooms "
United States
Chirag
The price is 4.451.182 ₫
6.544.306 ₫ total
includes taxes & fees
22 Dec - 23 Dec
Marriott Marquis San Diego Marina
Terrace/patio
Wyndham San Diego Bayside

Wyndham San Diego Bayside

Wyndham San Diego Bayside
4.0 star property
22 km from Mira Mesa
8.4 out of 10, Very good, (6041)
"Always an amazing stay"
United States
Jana
The price is 3.556.472 ₫
4.886.687 ₫ total
includes taxes & fees
22 Dec - 23 Dec
Wyndham San Diego Bayside
Hot springs
The Atwood Hotel San Diego - SeaWorld/Zoo

The Atwood Hotel San Diego - SeaWorld/Zoo

The Atwood Hotel San Diego - SeaWorld/Zoo
3.0 star property
17.6 km from Mira Mesa
8.0 out of 10, Very good, (1838)
"Clean and helpful staff, thank you !"
United States
Bora
The Atwood Hotel San Diego - SeaWorld/Zoo
Terrace/patio
Ayres Hotel Vista Carlsbad

Ayres Hotel Vista Carlsbad

Ayres Hotel Vista Carlsbad
3.5 star property
25.3 km from Mira Mesa
9.6 out of 10, Exceptional, (1933)
"Great Breakfast, clean rooms, easy parking"
United States
Detang
The price is 3.316.824 ₫
3.655.087 ₫ total
includes taxes & fees
22 Dec - 23 Dec
Ayres Hotel Vista Carlsbad
Lobby
Best Western Carlsbad by the Sea

Best Western Carlsbad by the Sea

Best Western Carlsbad by the Sea
2.5 star property
26.5 km from Mira Mesa
8.0 out of 10, Very good, (1044)
"Friendly staff, easy check in & check out."
United States
Julie
The price is 2.214.407 ₫
2.484.453 ₫ total
includes taxes & fees
11 Jan - 12 Jan 2026
Best Western Carlsbad by the Sea
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Where to stay in Mira Mesa

Find the best Mira Mesa areas for the activities you enjoy most.

Downtown San Diego

Known for its fantastic nightlife, fascinating museums and beautiful waterfront views, there's plenty to explore in Downtown San Diego. Top attractions like Petco Park and Port of San Diego are major draws. Catch the metro at Civic Center Station or Civic Center Station to see more of the city.

Gaslamp Quarter featuring a bar, night scenes and street scenes

Gaslamp Quarter

Cosy bars interesting history and top sights from Gaslamp Museum at the Davis-Horton House to Lyceum Theatre – discover Gaslamp Quarter, a destination also famous for its shopping.

Pacific Beach Park showing a beach

Pacific Beach

The stunning beaches and fantastic nightlife are just a few highlights of Pacific Beach. Make a stop by Mission Bay or Crystal Pier while you're exploring the area.

Belmont Park featuring a park and rides

Mission Beach

If you're spending some time in Mission Beach, Mission Beach and Mission Bay are top sights worth seeing.

Ocean Beach

Ocean Beach is beloved for its stunning beaches. Take some time to explore sights in the area like Ocean Beach Pier and Dog Beach.

Top Mira Mesa Hotel Reviews

The DEXTRO Little Italy, BW Premier Collection

The DEXTRO Little Italy, BW Premier Collection

10/10 Excellent
"The room was comfortable & the staff was incredibly friendly. The location is also ideal for exploration and looking around. Really solid pick."
Michael 5-night trip
Posted 1 day ago
The DEXTRO Little Italy, BW Premier Collection

Frequently asked questions

What's it like in Mira Mesa?
Mira Mesa is a neighbourhood that travellers like for its restaurants and bars. Consider a visit to Regal Edwards Mira Mesa as part of your Mira Mesa travel plans.
How many hotels should I expect to find in the Mira Mesa area?
Expedia has 45 hotels and other accommodation options in Mira Mesa to choose from, making this an ideal home base for exploring the greater San Diego area.
If I need to cancel my hotel reservation in Mira Mesa, will I receive a refund?
Yes! Most room reservations are fully refundable as long as you cancel prior to the accommodation's cancellation deadline, which often is within 24-48 hours of your check-in date. If you booked a non-refundable reservation, it might still be possible to cancel it and get a refund within a 24-hour period of booking. Add dates, click "Search", then use the "fully refundable" filter to get the best deals in Mira Mesa.
What is there to do in this San Diego neighbourhood?
Regal Edwards Mira Mesa is an attraction you might want to check out while you're in Mira Mesa. While you're out sightseeing in San Diego, make sure that you visit other sights such as Rancho Penasquitos Tennis Center or Lake Miramar.