Search Hotels Near Murphy Island, Palmyra

Start date: Check-in selected.
To Date
End date: Check-out

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
1 Dec - 2 Dec
Tomorrow
2 Dec - 3 Dec
This weekend
5 Dec - 7 Dec
Next weekend
12 Dec - 14 Dec

Filter by

Guest rating
Guest rating
Star rating

Top Trending Hotels Near Murphy Island

Exterior
Sleep Inn & Suites Hannibal West

Sleep Inn & Suites Hannibal West

2.5 star property
6.1 km from Murphy Island
9.6 out of 10, Exceptional, (1009)
"great stay!"
United States
Guy
The price is 2.666.820 ₫
3.089.511 ₫ total
includes taxes & fees
28 Dec - 29 Dec
Sleep Inn & Suites Hannibal West
Indoor pool, seasonal outdoor pool, pool umbrellas, pool loungers
Best Western On The River

Best Western On The River

2.5 star property
4.7 km from Murphy Island
8.6 out of 10, Excellent, (1006)
"Walkable to the historic downtown area and great breakfast choices."
United States
Dave
The price is 2.899.886 ₫
3.330.426 ₫ total
includes taxes & fees
2 Dec - 3 Dec
Best Western On The River
55-inch TV with cable channels, Netflix, Hulu
Riverside Inn Hannibal

Riverside Inn Hannibal

2.5 star property
4.9 km from Murphy Island
9.4 out of 10, Exceptional, (164)
"Great place to stay!"
United States
Sandy
The price is 3.648.041 ₫
5.098.182 ₫ total
includes taxes & fees
3 Dec - 4 Dec
Riverside Inn Hannibal
Lobby
Quality Inn & Suites Hannibal West

Quality Inn & Suites Hannibal West

2.5 star property
6 km from Murphy Island
8.0 out of 10, Very good, (1019)
"Nice place to stay- friendly staff, good breakfast options and nice clean room."
United States
Mary Beth
The price is 2.491.493 ₫
2.886.395 ₫ total
includes taxes & fees
8 Dec - 9 Dec
Quality Inn & Suites Hannibal West
Deluxe Room | Down duvets, blackout curtains, iron/ironing board, free WiFi
Lighthouse Inn & Suites

Lighthouse Inn & Suites

4.0 star property
4.3 km from Murphy Island
8.8 out of 10, Excellent, (23)
"Very nice room, close enough to walk to riverfront attractions. "
United States
Robert
The price is 4.451.941 ₫
5.113.053 ₫ total
includes taxes & fees
2 Dec - 3 Dec
Lighthouse Inn & Suites
Front of property
Garden House Bed and Breakfast

Garden House Bed and Breakfast

2.0 star property
4.9 km from Murphy Island
8.6 out of 10, Excellent, (35)
"Overall stay was great and the host chris is great aswell nothing bad to say about any aspect of our stay!"
United States
Josh
The price is 2.011.649 ₫
2.310.379 ₫ total
includes taxes & fees
2 Dec - 3 Dec
Garden House Bed and Breakfast
Lobby sitting area
Motel 6 Hannibal, MO

Motel 6 Hannibal, MO

2.0 star property
5.7 km from Murphy Island
7.4 out of 10, Good, (1009)
"Very clean rooms and staff is very friendly "
United States
Sherrie
The price is 1.530.488 ₫
1.757.754 ₫ total
includes taxes & fees
10 Dec - 11 Dec
Motel 6 Hannibal, MO
Exterior
Super 8 by Wyndham Hannibal

Super 8 by Wyndham Hannibal

2.0 star property
5.6 km from Murphy Island
7.2 out of 10, Good, (1005)
"My stay was excellent staff very friendly and breakfast was always great "
United States
Sherrie
The price is 1.713.725 ₫
1.968.214 ₫ total
includes taxes & fees
2 Dec - 3 Dec
Super 8 by Wyndham Hannibal
Indoor pool, pool loungers
Comfort Inn & Suites - Hannibal

Comfort Inn & Suites - Hannibal

2.5 star property
7.3 km from Murphy Island
7.6 out of 10, Good, (658)
"The beds were super comfy"
United States
Jayme
The price is 2.349.122 ₫
2.777.061 ₫ total
includes taxes & fees
14 Dec - 15 Dec
Comfort Inn & Suites - Hannibal
Desk, laptop workspace, iron/ironing board, free WiFi
Baymont by Wyndham Hannibal

Baymont by Wyndham Hannibal

2.5 star property
7.4 km from Murphy Island
6.4 out of 10, (734)
" There actually was a pool & there actually was a hot breakfast. It didn't just say there was & not have what was listed. One of the best we've been to as of late. Would stay again if in the area. "
United States
Thomas
The price is 1.501.487 ₫
1.736.136 ₫ total
includes taxes & fees
1 Jan - 2 Jan 2026
Baymont by Wyndham Hannibal
Room, 2 Queen Beds, Non Smoking | Desk, laptop workspace, free WiFi, bed sheets
Days Inn by Wyndham Hannibal

Days Inn by Wyndham Hannibal

2.0 star property
7.4 km from Murphy Island
7.4 out of 10, Good, (214)
"Left before breakfast great cup of coffee"
United States
David
The price is 1.708.452 ₫
1.962.158 ₫ total
includes taxes & fees
17 Dec - 18 Dec
Days Inn by Wyndham Hannibal
Lobby sitting area
Howard Johnson BY Wyndham Hannibal

Howard Johnson BY Wyndham Hannibal

2.0 star property
7.5 km from Murphy Island
7.2 out of 10, Good, (148)
"The staff are stellar! We didn’t need for anything and the pool is heated and clean! We’ve stayed here before and we will definitely choose this place again if we’re in the area."
United States
Terry
The price is 1.456.666 ₫
1.684.460 ₫ total
includes taxes & fees
1 Jan - 2 Jan 2026
Howard Johnson BY Wyndham Hannibal
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top Murphy Island Hotel Reviews

Heritage Hotel Quincy

Heritage Hotel Quincy

10/10 Excellent
"The room was VERY clean and comfortable. It had all of the amenities needed. I would recommend this hotel to friends. "
Gina 1-night trip
Posted 7 days ago
Heritage Hotel Quincy

Hotels near other Murphy Island attractions

Mark Twain Memorial Lighthouse

4.3/5 (93 reviews)
You can find out about the history of Hannibal with a trip to Mark Twain Memorial Lighthouse. While in this walkable area, you can savour the top-notch restaurants.
See properties

Riverview Park

You can find out about the history of Hannibal when you stop by Riverview Park. While in this family-friendly area, you can savour the top-notch restaurants.
See properties

Frequently asked questions

What's the area like around Murphy Island?
Murphy Island is located in Palmyra. You'll find 52 hotels and other accommodations within a few miles for a convenient home base.
How many hotels will I be able to find near Murphy Island?
Expedia has 52 hotels and other accommodation options a few miles from Murphy Island.
If I need to cancel the hotel reservation for my stay near Murphy Island, will I receive a refund?
Yes, you'll find most hotel reservations are fully refundable if you cancel prior to the accommodation's cancellation deadline, which is often 24 or 48 hours before the scheduled arrival. If your reservation is non-refundable, it might still be possible to cancel it and receive a refund within a 24-hour period of your booking. Add your dates and click on "Search", then you can use the "fully refundable" filter to view the best deals available near Murphy Island.
What can I see and do near Murphy Island?
Jim's Journey: The Huck Finn Freedom Center, Mark Twain Boyhood Home and Museum and Molly Brown Museum and Home feature captivating exhibits. Mark Twain Memorial Lighthouse, Rockcliffe Mansion and Planters Barn Theater are landmarks that you won't want to miss. You might spend a leisurely day outdoors at Sawyer's Creek Fun Park and Sodalis Nature Preserve.

Explore a world of travel with Expedia