Mytilene Holidays

Book a Hotel + Flight or Car together to unlock savings

Top hotels in Mytilene

Heliotrope Hotels
Heliotrope Hotels
4 out of 5
Varia, Mytilene, Lesvos, Lesvos Island
The price is 3.836.060 ₫ per night from 29 Jun to 30 Jun
3.836.060 ₫
4.507.447 ₫ total
29 Jun - 30 Jun
includes taxes & fees
8.4/10 Very Good! (178 reviews)
"I LOVE the staff here. They are consistently friendly and helpful. The pool was being worked on and that was a bummer."

Reviewed on 6 Jun 2025

Heliotrope Hotels
Theofilos Paradise Boutique Hotel
Theofilos Paradise Boutique Hotel
4 out of 5
7, Skra str, Hatzidimitriou Park, Mytilene, Lesvos
9.6/10 Exceptional! (142 reviews)
"Our fourth time at this hotel - everything was great."

Reviewed on 13 Jun 2025

Theofilos Paradise Boutique Hotel
The Loriet
The Loriet
4 out of 5
Vareia, Mitilene, Lesvos, Lesvos Island
The price is 2.994.545 ₫ per night from 30 Jun to 1 Jul
2.994.545 ₫
3.586.151 ₫ total
30 Jun - 1 Jul
includes taxes & fees
8.2/10 Very Good! (61 reviews)
Hospitality
"Wonderful place for several days. So authentic, see view, hospitality"

Reviewed on 14 Jun 2025

The Loriet
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a Mytilene holiday package cost?
You can grab a holiday package to this top destination on Expedia. But how much your holiday to Mytilene costs will depend on the season, length of stay and hotel choice.
What are the cheapest months to go to Mytilene?
If you're hoping to score a cheap Mytilene holiday package, consider visiting in February, March and December. You're likely to find lower prices on flights and accommodation during these months --- ideal for budget-conscious travellers.
How many days is enough for Mytilene?
With a well-organised schedule, you can easily tick off the main Mytilene attractions in a few days. But if you'd like to discover lesser-known spots or go on day trips, think about booking your Mytilene holiday for longer.
Is it worth booking a holiday package to Mytilene?
Well known for its history, festivals and family-friendly attractions, a Mytilene holiday is a hit with all types of travellers. Be sure to check out top sights like Olive-press Museum of Archipelagos Society and Temple of Messon, and consider renting a set of wheels for day trips to discover even more.
How to find the best Mytilene package deals?
Use Expedia's handy filters to help you find some fabulous Mytilene package deals. When you start your search, just set your maximum budget and then order the results by "Price: low to high." If you want to save, plan your trip for midweek, or browse for Mytilene package deals in the off-season. Play around with your travel dates and you may score even better discounts. As a rule of thumb, it's usually best to book your holiday package well in advance.
Is it cheaper to book a Mytilene holiday as a package?
An Expedia holiday package could land you great savings when compared to booking stays and flights separately. Better still, you can personalise your Mytilene escape to match your exact needs. Pick your preferred flight time, select the hotel type and add a car rental. Check out our great deals to see how much you can save.
When to book a holiday package to Mytilene?
Land incredible discounts by reserving your flights ahead of time with Expedia. If being spontaneous is more your thing, snap up one of our last-minute deals for an impromptu Mytilene escape.
How to plan a trip to Mytilene?

  1. Pick your dates: The things you want to do in Mytilene and your preferred season can help you decide when to go.
  2. Set your budget: Factor in costs such as flights, food and transportation when calculating how much to save for your trip to Mytilene. Then, choose a hotel that suits your budget, whether that's a wallet-friendly stay or a high-end getaway.
  3. Decide your trip length: Think about how much time you'd like to spend discovering Mytilene. Plan your itinerary so you can get to all the experiences and attractions you're interested in at a leisurely pace.
  4. Bundle your bookings: With your travel dates in place, you can combine your flights, car rental, hotels and more into a customised Mytilene holiday package.

Popular places to visit