
New Madrid Holidays
Book a Hotel + Flight or Car together to unlock savings
Top hotels in New Madrid

Hampton Inn Sikeston
1240 Commerce Drive Sikeston MO
Fully refundableReserve now, pay when you stay
The price is 2.784.976 ₫ per night from 21 Jun to 22 Jun
2.784.976 ₫
3.153.288 ₫ total
21 Jun - 22 Jun
includes taxes & fees
9/10 Wonderful! (569 reviews)
"Dirt on bathroom floor. Bed mattress hard and lumpy."
Reviewed on 28 May 2026

Reelfoot Lake Inn
1520 State Route 21 East Tiptonville TN
The price is 1.834.542 ₫ per night from 1 Jun to 2 Jun
1.834.542 ₫
2.105.137 ₫ total
1 Jun - 2 Jun
includes taxes & fees
7.2/10 Good! (493 reviews)
"Only one light bulb in the bathroom, pool was nasty, no ice bucket or machine, no hair dryer"
Reviewed on 25 May 2026

Fairfield Inn & Suites by Marriott Sikeston
1239 Commerce Drive Sikeston MO
Fully refundableReserve now, pay when you stay
The price is 2.896.080 ₫ per night from 11 Jun to 12 Jun
2.896.080 ₫
3.279.087 ₫ total
11 Jun - 12 Jun
includes taxes & fees
9.4/10 Exceptional! (84 reviews)
"Great stay, kind staff, very clean property."
Reviewed on 30 May 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Popular places to visit
River Ridge Winery
You can enjoy a tasting or tour at River Ridge Winery during your travels to New Madrid. Amble around the area's parks or experience its museums.
Hunter-Dawson State Historic Site
You can browse the exhibits at Hunter-Dawson State Historic Site, a museum with a story of its own, during your trip to New Madrid. Amble around the area's parks or experience its museums.
New Madrid Historical Museum
You can study the exhibits at New Madrid Historical Museum, a museum with a storied past, during your travels to New Madrid. Amble around the area's parks or experience its museums.
