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Our top choices for Panama City holiday rentals

Arcadia Condo Suites

Arcadia Condo Suites
2.5 star property
Costa del Este
9.4 out of 10, Exceptional, (161)
"Everything was great, helpful staff, great room , clean, excellent service!"
United States
Gregory Walter
The price is 1.788.876 ₫
3.183.147 ₫ total
includes taxes & fees
3 Jan - 4 Jan 2026
Arcadia Condo Suites

La Isabela Suites

La Isabela Suites
3.5 star property
Casco Viejo
10.0 out of 10, Exceptional, (168)
"Wonderful charming property in the heart of the historic district. "
United States
Angela
La Isabela Suites

Studio Apartment with Ocean View

Studio Apartment with Ocean View
3.0 star property
Calidonia
10.0 out of 10, Exceptional, (1)
"Muy amables en general "
Mexico
Algis
The price is 1.709.955 ₫
1.880.951 ₫ total
includes taxes & fees
2 Jan - 3 Jan 2026
Studio Apartment with Ocean View

Yoo Panama & Arts Tower

Yoo Panama & Arts Tower
3.0 star property
Bella Vista
9.6 out of 10, Exceptional, (47)
"Nice stay"
United States
ANGEL
Yoo Panama & Arts Tower

La Palma Aparta Suite

La Palma Aparta Suite
3.0 star property
Amador
The price is 1.246.952 ₫
2.160.857 ₫ total
includes taxes & fees
16 Dec - 17 Dec
La Palma Aparta Suite

Las Clementinas

Las Clementinas
3.5 star property
Casco Viejo
9.4 out of 10, Exceptional, (170)
"The front desk receptionist was extremely helpful! The room was clean and comfortable! We would definitely stay again!"
United States
april
The price is 3.672.168 ₫
4.039.385 ₫ total
includes taxes & fees
19 Dec - 20 Dec
Las Clementinas

Living 73 Panamá by Boutique Apartments

Living 73 Panamá by Boutique Apartments
3.0 star property
San Francisco
The price is 1.212.226 ₫
5.211.311 ₫ total
includes taxes & fees
30 Dec - 31 Dec
Living 73 Panamá by Boutique Apartments

w Situated 1BR w Beautiful View in Calle 50

w Situated 1BR w Beautiful View in Calle 50
2.0 star property
Bella Vista
The price is 2.236.334 ₫
3.241.285 ₫ total
includes taxes & fees
16 Dec - 17 Dec
w Situated 1BR w Beautiful View in Calle 50

Swette Love 10 Minutes From the Airport Tocumen

Swette Love 10 Minutes From the Airport Tocumen
2.0 star property
Las Mañanitas
The price is 2.007.461 ₫
2.517.047 ₫ total
includes taxes & fees
21 Dec - 22 Dec
Swette Love 10 Minutes From the Airport Tocumen

Wanders Panama by Boutique Apartments

Wanders Panama by Boutique Apartments
4.0 star property
San Francisco
10.0 out of 10, Exceptional, (1)
"I will go again thank you so much"
United States
GISY ITZEL
The price is 4.209.120 ₫
8.652.372 ₫ total
includes taxes & fees
16 Dec - 17 Dec
Wanders Panama by Boutique Apartments

Mini Design By Wynwood House

Mini Design By Wynwood House
2.0 star property
Bella Vista
The price is 3.006.890 ₫
4.031.022 ₫ total
includes taxes & fees
16 Dec - 17 Dec
Mini Design By Wynwood House

Donovan By Wynwood House

Donovan By Wynwood House
3.0 star property
Casco Viejo
8.4 out of 10, Very good, (45)
"I always love to stay at Wynwood properties in Panama "
United States
Alberto B
The price is 1.799.399 ₫
2.768.549 ₫ total
includes taxes & fees
16 Dec - 17 Dec
Donovan By Wynwood House

Torres de Alba Hotel & Suites

Torres de Alba Hotel & Suites
3.5 star property
Bella Vista
8.8 out of 10, Excellent, (483)
"The buffet bar and great customer service. "
United States
Kayhiuska
Torres de Alba Hotel & Suites

w Central 1BR in Vibrant Obarrio

w Central 1BR in Vibrant Obarrio
2.0 star property
Bella Vista
The price is 2.771.801 ₫
3.830.299 ₫ total
includes taxes & fees
16 Dec - 17 Dec
w Central 1BR in Vibrant Obarrio

Charming 3 Bedroom Apartment in San Miguelito, Panama City

Charming 3 Bedroom Apartment in San Miguelito, Panama City
2.0 star property
José Domingo Espinar
The price is 1.890.102 ₫
2.079.112 ₫ total
includes taxes & fees
18 Dec - 19 Dec
Charming 3 Bedroom Apartment in San Miguelito, Panama City
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Panama City Hotel Reviews

Frequently asked questions

Can I find holiday rentals in Panama City?

Yes, there are holiday rentals in Panama City close to Panama Canal Railway, or you can select a more secluded option if you're looking for a relaxing stay. Tourists like the array of shops and top-notch restaurants in Panama City. While you're in the area, grab a bite or have a drink at the lively bars and cafes.

How many holiday rentals are there in Panama City?

With 55 Expedia holiday rentals, you're guaranteed to find just the right place for your Panama City stay.

What can I see and do in Panama City?

Cultural attractions include National Theater and Interoceanic Canal Museum, whereas Cinta Costera and Miraflores Locks are a couple of picturesque spots to enjoy the outdoors. Albrook Shopping Mall and Via Espana are other places to visit while you're in town.

What are holiday rentals like in Panama City?

Holiday rentals are privately owned properties you can book for a few days, or a quick weekend, in Panama City. Holiday rentals offer extras like WiFi and washers and dryers so you'll feel right at home. If you're concerned about a clean environment, holiday rentals can provide a sense of privacy away from public hotel lifts and lobbies bustling with people while still allowing you a great travel experience. You'll also get more space in a holiday rental than in a standard hotel, which is another reason why a holiday rental is a great choice for family gatherings.