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Check prices for these dates

In two weeks
26 Dec - 28 Dec
In two months
6 Feb - 8 Feb
In three months
6 Mar - 8 Mar
In four months
3 Apr - 5 Apr

Our top choices for Panama City holiday rentals

50-inch LED TV with satellite channels
Arcadia Condo Suites

Aparthotel in Costa del Este

Arcadia Condo Suites
2.5 star property
9.4 out of 10, Exceptional, (157)
"Everything was great, helpful staff, great room , clean, excellent service!"
United States
Gregory Walter
The price is 1.739.562 ₫
3.131.211 ₫ total
includes taxes & fees
15 Dec - 16 Dec
Arcadia Condo Suites
Outdoor pool
Boutique Apartments Panama

Apartment in Bella Vista

Boutique Apartments Panama
3.5 star property
7.6 out of 10, Good, (215)
"The view was amazing and the place was great could stay here again "
United States
Yonnette
Boutique Apartments Panama
Reception
Torres de Alba Hotel & Suites

Aparthotel in Bella Vista

Torres de Alba Hotel & Suites
3.5 star property
8.8 out of 10, Excellent, (483)
"The buffet bar and great customer service. "
United States
Kayhiuska
Torres de Alba Hotel & Suites
Outdoor pool, open 8:00 AM to 10:00 PM, pool umbrellas, pool loungers
Casco View Apartments

Condo in Santa Ana

Casco View Apartments
3.5 star property
9.2 out of 10, Wonderful, (52)
"Great stay, would recommend."
United States
Brooke
Casco View Apartments
Restaurant
Las Clementinas

Aparthotel in Casco Viejo

Las Clementinas
3.5 star property
9.4 out of 10, Exceptional, (169)
"Our stay at Las Clementinas was amazing. The ambiance, decor, and central location to all things in Casco Viejo made our trip magical. Not only was the hotel beautiful, the staff was incredibly warm, helpful and welcoming. The restaurant in the hotel was absolutely delicious. I would stay here ten times over. "
United States
Amanda
The price is 3.392.113 ₫
3.731.324 ₫ total
includes taxes & fees
13 Dec - 14 Dec
Las Clementinas
Apartment, 3 Bedrooms | Living area | 32-inch Smart TV with digital channels, TV, Netflix
Boutique Apartments Panamá Coco del Mar

Apartment in San Francisco

Boutique Apartments Panamá Coco del Mar
3.5 star property
7.4 out of 10, Good, (152)
"Clean room good place to stay "
United States
Gideon
The price is 1.366.347 ₫
5.198.233 ₫ total
includes taxes & fees
14 Dec - 15 Dec
Boutique Apartments Panamá Coco del Mar
Interior detail
La Isabela Suites

Aparthotel in Casco Viejo

La Isabela Suites
3.5 star property
10.0 out of 10, Exceptional, (166)
"The room was spotless, the location perfect, and the staff was absolutely superb!"
United States
Gregory
La Isabela Suites
Apartment (3G) | Living area | 40-inch Smart TV with cable channels
La Cuadra by Wynwood House

Condo in El Chorrillo

La Cuadra by Wynwood House
3.5 star property
9.2 out of 10, Wonderful, (44)
"Love the property. You are right at the start of the nice part of casco viejo but the blocks around it are rough and ugly. The police are very prominent so it's safe but be on alert"
United States
Carlos
The price is 3.373.696 ₫
4.369.991 ₫ total
includes taxes & fees
14 Dec - 15 Dec
La Cuadra by Wynwood House
Exterior
Yoo Panamá by Boutique Apartments

Apartment in Bella Vista

Yoo Panamá by Boutique Apartments
3.5 star property
8.2 out of 10, Very good, (48)
"Great location but not enough towels in the room "
United States
Damion
The price is 1.779.097 ₫
5.620.630 ₫ total
includes taxes & fees
14 Dec - 15 Dec
Yoo Panamá by Boutique Apartments
Apartment (10D) | Balcony
San Francisco by Wynwood House

Apartment in San Francisco

San Francisco by Wynwood House
3.0 star property
9.2 out of 10, Wonderful, (56)
"Clean and walkable location"
United States
Tamera
The price is 3.700.523 ₫
4.729.500 ₫ total
includes taxes & fees
12 Dec - 13 Dec
San Francisco by Wynwood House
Exterior
ESHEL SUITES PANAMA

Aparthotel in San Francisco

ESHEL SUITES PANAMA
2.5 star property
10.0 out of 10, Exceptional, (5)
"Loved the property and the location, it was clean , nice and I really enjoyed my stay there"
United States
Aron
ESHEL SUITES PANAMA
Outdoor pool
Boutique Apartments Atlapa

Apartment in San Francisco

Boutique Apartments Atlapa
3.0 star property
8.0 out of 10, Very good, (26)
"I had an excellent stay here ! It was a very amazing the host is an amazing person thank you for making My stay great❤️"
United States
Shamia
Boutique Apartments Atlapa
Outdoor pool, free pool cabanas, pool loungers
Yoo Panama & Arts Tower

Apartment in Bella Vista

Yoo Panama & Arts Tower
3.0 star property
9.4 out of 10, Exceptional, (46)
"Nice stay"
United States
ANGEL
Yoo Panama & Arts Tower
Apartment, 2 Bedrooms (CC2A) | Premium bedding, soundproofing, iron/ironing board, free WiFi
Casa Contemporanea by Wynwood House

Apartment in Casco Viejo

Casa Contemporanea by Wynwood House
4.0 star property
8.2 out of 10, Very good, (20)
"Great place!"
United States
Jad
The price is 3.534.474 ₫
4.546.846 ₫ total
includes taxes & fees
12 Dec - 13 Dec
Casa Contemporanea by Wynwood House
Apartment, 3 Bedrooms (CM5) | Living room | 55-inch Smart TV with digital channels
Casa Mallet by Wynwood House

Apartment in Casco Viejo

Casa Mallet by Wynwood House
4.0 star property
9.8 out of 10, Exceptional, (25)
" It was very relaxing to stay at the historical and cutely renovated apartment. Great aesthetic. Lively apartment, very well decorated! Right the middle of everything in the beautiful town of Casco Veijo. Vibrant lanes, boutique stores, cafes and restaurants near by. We had an amazing time staying for 2 nights at this apartment. "
United States
Navyatha
The price is 9.820.618 ₫
11.527.498 ₫ total
includes taxes & fees
11 Jan - 12 Jan 2026
Casa Mallet by Wynwood House
Deluxe Apartment | Living area | 40-inch Smart TV with cable channels
La Moderna by Wynwood House

Apartment in Casco Viejo

La Moderna by Wynwood House
3.0 star property
7.4 out of 10, Good, (40)
"The nightlife around there was incredible"
United States
Felix
The price is 1.605.544 ₫
2.635.879 ₫ total
includes taxes & fees
17 Dec - 18 Dec
La Moderna by Wynwood House
Outdoor pool, a rooftop pool
Delightful Ocean View

Apartment in San Francisco

Delightful Ocean View
3.5 star property
8.0 out of 10, Very good, (2)
"The apartment was in a good location but most of the pictures in this listing were of the lobby and building. The showerheads in both bathrooms kept moving which caused water to go everywhere, and we only had two pillows on the main bed and one on each twin bed, and the linens were lacking, there is also no outdoor furniture and the apartment is right above the pool which occasionally was noisy. Also there aren’t great instructions to check in or check out. There are better places to stay in...
United States
Laura
Delightful Ocean View
Apartment, 2 Bedrooms (1B) | Living area | 40-inch Smart TV with cable channels
Casa Love by Wynwood House

Apartment in Casco Viejo

Casa Love by Wynwood House
3.0 star property
8.8 out of 10, Excellent, (19)
"It was absolutely wonderful. You just may need to bring your own soap for one of the bathrooms. Perhaps that was not typical though. I especially appreciated the cleanliness of the property, the view of the water, and the easy-to-use AC. "
United States
Tamu
The price is 2.490.736 ₫
3.609.591 ₫ total
includes taxes & fees
14 Dec - 15 Dec
Casa Love by Wynwood House
Apartment (20) | Iron/ironing board, free WiFi, bed sheets
La Manzana by Wynwood House

Apartment in Santa Ana

La Manzana by Wynwood House
3.0 star property
7.2 out of 10, Good, (15)
"Great hotel. Very close to Casco viejo"
United States
LUCILA
The price is 2.134.917 ₫
3.073.227 ₫ total
includes taxes & fees
14 Dec - 15 Dec
La Manzana by Wynwood House
Apartment (1D) | Living area | 40-inch Smart TV with cable channels
Casa La Costa By Wynwood House

Apartment in Casco Viejo

Casa La Costa By Wynwood House
3.5 star property
8.4 out of 10, Very good, (20)
"Great location. At the border of renovated areas but an extremely go deal for this great property. "
United States
William
The price is 3.273.539 ₫
4.470.674 ₫ total
includes taxes & fees
14 Dec - 15 Dec
Casa La Costa By Wynwood House
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Panama City Hotel Reviews

Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

10/10 Excellent
"Always nice to stay and have experience the service of the company excels my expectation "
Dana 1-night trip
Posted 2 days ago
Hotel Riu Plaza Panama

Frequently asked questions

Can I find holiday rentals in Panama City?

Yes, there are holiday rentals in Panama City close to Panama Canal Railway, or you can select a more secluded option if you're looking for a relaxing stay. Tourists like the array of shops and top-notch restaurants in Panama City. While you're in the area, grab a bite or have a drink at the lively bars and cafes.

How many holiday rentals are there in Panama City?

With 55 Expedia holiday rentals, you're guaranteed to find just the right place for your Panama City stay.

What can I see and do in Panama City?

Cultural attractions include National Theater and Interoceanic Canal Museum, whereas Cinta Costera and Miraflores Locks are a couple of picturesque spots to enjoy the outdoors. Albrook Shopping Mall and Via Espana are other places to visit while you're in town.

What are holiday rentals like in Panama City?

Holiday rentals are privately owned properties you can book for a few days, or a quick weekend, in Panama City. Holiday rentals offer extras like WiFi and washers and dryers so you'll feel right at home. If you're concerned about a clean environment, holiday rentals can provide a sense of privacy away from public hotel lifts and lobbies bustling with people while still allowing you a great travel experience. You'll also get more space in a holiday rental than in a standard hotel, which is another reason why a holiday rental is a great choice for family gatherings.