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Our top choices for Panama City holiday rentals

Las Clementinas

Las Clementinas
3.5 star property
Casco Viejo
9.4 out of 10, Exceptional, (171)
"The front desk receptionist was extremely helpful! The room was clean and comfortable! We would definitely stay again!"
United States
april
The price is 4.247.904 ₫
4.672.773 ₫ total
includes taxes & fees
13 Jan - 14 Jan 2026
Las Clementinas

La Isabela Suites

La Isabela Suites
3.5 star property
Casco Viejo
10.0 out of 10, Exceptional, (171)
"Wonderful charming property in the heart of the historic district. "
United States
Angela
La Isabela Suites

Arcadia Condo Suites

Arcadia Condo Suites
2.5 star property
Costa del Este
9.4 out of 10, Exceptional, (162)
"Everything was great, helpful staff, great room , clean, excellent service!"
United States
Gregory Walter
The price is 1.816.356 ₫
3.214.161 ₫ total
includes taxes & fees
2 Jan - 3 Jan 2026
Arcadia Condo Suites

YC 1701l Apartamento 2 BDR Av Balboa

YC 1701l Apartamento 2 BDR Av Balboa
2.5 star property
Bella Vista
The price is 3.606.388 ₫
4.888.367 ₫ total
includes taxes & fees
25 Dec - 26 Dec
YC 1701l Apartamento 2 BDR Av Balboa

La Palma Aparta Suite

La Palma Aparta Suite
3.0 star property
Amador
The price is 1.247.758 ₫
2.162.254 ₫ total
includes taxes & fees
22 Dec - 23 Dec
La Palma Aparta Suite

Living 73 Panamá by Boutique Apartments

Living 73 Panamá by Boutique Apartments
3.0 star property
San Francisco
The price is 591.579 ₫
4.468.963 ₫ total
includes taxes & fees
22 Dec - 23 Dec
Living 73 Panamá by Boutique Apartments

Wanders Panama by Boutique Apartments

Wanders Panama by Boutique Apartments
4.0 star property
San Francisco
10.0 out of 10, Exceptional, (1)
"I will go again thank you so much"
United States
GISY ITZEL
The price is 2.282.291 ₫
6.535.460 ₫ total
includes taxes & fees
21 Dec - 22 Dec
Wanders Panama by Boutique Apartments

Yoo Panama & Arts Tower

Yoo Panama & Arts Tower
3.0 star property
Bella Vista
9.4 out of 10, Exceptional, (49)
"Nice stay"
United States
ANGEL
Yoo Panama & Arts Tower

Mini Design By Wynwood House

Mini Design By Wynwood House
2.0 star property
Bella Vista
The price is 3.237.852 ₫
4.285.547 ₫ total
includes taxes & fees
21 Dec - 22 Dec
Mini Design By Wynwood House

Casa Contemporanea by Wynwood House

Casa Contemporanea by Wynwood House
4.0 star property
Casco Viejo
8.2 out of 10, Very good, (20)
"Great place!"
United States
Jad
The price is 3.885.422 ₫
4.932.064 ₫ total
includes taxes & fees
21 Dec - 22 Dec
Casa Contemporanea by Wynwood House

Swette Love 10 Minutes From the Airport Tocumen

Swette Love 10 Minutes From the Airport Tocumen
2.0 star property
Las Mañanitas
The price is 2.006.402 ₫
2.515.719 ₫ total
includes taxes & fees
25 Dec - 26 Dec
Swette Love 10 Minutes From the Airport Tocumen

Torres de Alba Hotel & Suites

Torres de Alba Hotel & Suites
3.5 star property
Bella Vista
8.8 out of 10, Excellent, (483)
"The buffet bar and great customer service. "
United States
Kayhiuska
Torres de Alba Hotel & Suites

Studio Apartment with Ocean View

Studio Apartment with Ocean View
3.0 star property
Calidonia
8.0 out of 10, Very good, (2)
"It was similar to a hotel room, but a little smaller.. the bed is big enough for just one person and check in was the most difficult thing he had to wait outside in the rain and download apps"
United States
Gwendolyn
The price is 1.711.060 ₫
1.882.166 ₫ total
includes taxes & fees
2 Jan - 3 Jan 2026
Studio Apartment with Ocean View

w Bright 1BR w Private Balcony in San Francisco

w Bright 1BR w Private Balcony in San Francisco
2.0 star property
San Francisco
The price is 2.899.708 ₫
3.971.502 ₫ total
includes taxes & fees
18 Jan - 19 Jan 2026
w Bright 1BR w Private Balcony in San Francisco
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Panama City Hotel Reviews

Frequently asked questions

Can I find holiday rentals in Panama City?

Yes, there are holiday rentals in Panama City close to Panama Canal Railway, or you can select a more secluded option if you're looking for a relaxing stay. Tourists like the array of shops and top-notch restaurants in Panama City. While you're in the area, grab a bite or have a drink at the lively bars and cafes.

How many holiday rentals are there in Panama City?

With 54 Expedia holiday rentals, you're guaranteed to find just the right place for your Panama City stay.

What can I see and do in Panama City?

Cultural attractions include National Theater and Interoceanic Canal Museum, whereas Cinta Costera and Miraflores Locks are a couple of picturesque spots to enjoy the outdoors. Albrook Shopping Mall and Via Espana are other places to visit while you're in town.

What are holiday rentals like in Panama City?

Holiday rentals are privately owned properties you can book for a few days, or a quick weekend, in Panama City. Holiday rentals offer extras like WiFi and washers and dryers so you'll feel right at home. If you're concerned about a clean environment, holiday rentals can provide a sense of privacy away from public hotel lifts and lobbies bustling with people while still allowing you a great travel experience. You'll also get more space in a holiday rental than in a standard hotel, which is another reason why a holiday rental is a great choice for family gatherings.