
Panhandle Holidays
Book a Hotel + Flight or Car together to unlock savings
Photo by Pat Long
Top hotels in Panhandle

The Cactus Cove Inn and Suites
2501 E Interstate Dr, Amarillo, TX
Fully refundableReserve now, pay when you stay
The price is 2.060.091 ₫ per night from 18 Aug to 19 Aug
2.060.091 ₫
2.369.104 ₫ total
18 Aug - 19 Aug
includes taxes & fees
7.8/10 Good! (1,884 reviews)
"My kids loved all the things to do! Beds were comfortable"
Reviewed on 15 Aug 2025

La Quinta Inn by Wyndham Amarillo Mid-City
1708 I-40 E, Amarillo, TX
Fully refundableReserve now, pay when you stay
The price is 1.384.903 ₫ per night from 24 Aug to 25 Aug
1.384.903 ₫
1.592.639 ₫ total
24 Aug - 25 Aug
includes taxes & fees
7.2/10 Good! (1,131 reviews)
"Very friendly efficient knowledgeable fluent English and Spanish."
Reviewed on 15 Aug 2025

Baymont by Wyndham Amarillo East
1700 I-40 E, Amarillo, TX
Fully refundableReserve now, pay when you stay
The price is 1.631.615 ₫ per night from 21 Aug to 22 Aug
1.631.615 ₫
1.876.356 ₫ total
21 Aug - 22 Aug
includes taxes & fees
8.4/10 Very Good! (1,579 reviews)
Reasonable for short time
"Older hotel but convenient location, breakfast good basic. Management /staff very friendly. Helpful. 2 floors, no elevator so tell them if need 1st floor. Reasonable price for basic. close to Sam's"
Reviewed on 13 Aug 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Popular places to visit
VW Slug Bug Ranch
Learn about the local history of Panhandle when you spend time at VW Slug Bug Ranch. Take in the museums while you're in the area.