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Our top choices for Piazza del Duomo hotels

Junior Suite, Terrace | Terrace/patio
Dimore delle Zagare Ortigia

Dimore delle Zagare Ortigia

Dimore delle Zagare Ortigia
Ortigia, 0.3 km from Piazza del Duomo
9.8 out of 10, Exceptional, (160)
"It was a perfect location"
United States
Susan
Dimore delle Zagare Ortigia
Front of property ��– evening/night
Algila' Ortigia Charme Hotel

Algila' Ortigia Charme Hotel

Algila' Ortigia Charme Hotel
4.0 star property
Ortigia, 0.4 km from Piazza del Duomo
9.6 out of 10, Exceptional, (909)
"Staff were very kind and helpful. Room was clean and with all needed amenities. Bathroom was very clean."
United States
Teddy
Algila' Ortigia Charme Hotel
Front of property
Maniace Boutique Hotel Ortigia UNA Esperienze

Maniace Boutique Hotel Ortigia UNA Esperienze

Maniace Boutique Hotel Ortigia UNA Esperienze
Ortigia, 0.3 km from Piazza del Duomo
9.8 out of 10, Exceptional, (59)
"All excellent and highly recommended "
United States
Banner
The price is 4.764.987 ₫
5.549.624 ₫ total
includes taxes & fees
11 Jan - 12 Jan 2026
Maniace Boutique Hotel Ortigia UNA Esperienze
Superior Triple Room, Sea View | Memory-foam beds, in-room safe, individually furnished, desk
Fortaleza Charme House

Fortaleza Charme House

Fortaleza Charme House
Santa Lucia, 0.7 km from Piazza del Duomo
10.0 out of 10, Exceptional, (27)
"Great central location."
United States
Craig
The price is 4.424.584 ₫
5.043.914 ₫ total
includes taxes & fees
5 Jan - 6 Jan 2026
Fortaleza Charme House
Comfort Apartment | Balcony
Matteotti Luxury Residence

Matteotti Luxury Residence

Matteotti Luxury Residence
Ortigia, 0.3 km from Piazza del Duomo
9.8 out of 10, Exceptional, (8)
"Property was clean, safe, and modern. Very efficient check in and out and staff communication was timely and informative. Great place to stay!"
Canada
Andrea
The price is 3.308.171 ₫
5.854.193 ₫ total
includes taxes & fees
5 Jan - 6 Jan 2026
Matteotti Luxury Residence
Deluxe Room, Balcony, Sea View | Premium bedding, down duvets, minibar, in-room safe
Dimore delle Zagare Molo

Dimore delle Zagare Molo

Dimore delle Zagare Molo
1.0 star property
1.1 km from Piazza del Duomo
10.0 out of 10, Exceptional, (5)
"The girl at the front desk was awesome She sent me on a great walking tour and had me go to a fantastic dinner with a 15% discount "
United States
Bart
The price is 3.487.272 ₫
3.975.586 ₫ total
includes taxes & fees
17 Jan - 18 Jan 2026
Dimore delle Zagare Molo
Reception
Palazzo Artemide - VRetreats, SLH Collection

Palazzo Artemide - VRetreats, SLH Collection

Palazzo Artemide - VRetreats, SLH Collection
4.0 star property
Ortigia, 0.1 km from Piazza del Duomo
9.4 out of 10, Exceptional, (659)
"Great hotel"
United States
Caterina
The price is 5.678.706 ₫
6.554.715 ₫ total
includes taxes & fees
23 Dec - 24 Dec
Palazzo Artemide - VRetreats, SLH Collection
Property entrance
Giuggiulena Villa

Giuggiulena Villa

Giuggiulena Villa
3.0 star property
Santa Lucia, 1.7 km from Piazza del Duomo
10.0 out of 10, Exceptional, (126)
"Fantastic stay. Made to feel very welcome and what a lovely relaxing place to stay. Evening meal was exceptional. "
United States
Paul
The price is 5.748.178 ₫
6.552.867 ₫ total
includes taxes & fees
6 Jan - 7 Jan 2026
Giuggiulena Villa
Classic Double Room, Partial Sea View | View from room
Charme Hotel Henry's House

Charme Hotel Henry's House

Charme Hotel Henry's House
4.0 star property
Ortigia, 0.4 km from Piazza del Duomo
9.6 out of 10, Exceptional, (322)
"Great location. Very friendly and helpful staff. Nice breakfast."
United States
Alan
The price is 7.964.251 ₫
9.068.814 ₫ total
includes taxes & fees
2 Jan - 3 Jan 2026
Charme Hotel Henry's House
Front of property
Byssus Suites

Byssus Suites

Byssus Suites
1.2 km from Piazza del Duomo
9.8 out of 10, Exceptional, (35)
"Very nice hotel with spacious, comfortable rooms and friendly staff. The recommendations for the restaurants and activities in the area were useful and nice. The breakfast buffet had a nice variety of options and all products were super fresh. Highly recommend this hotel!"
Netherlands
Annelisa
The price is 6.050.601 ₫
6.897.672 ₫ total
includes taxes & fees
23 Dec - 24 Dec
Byssus Suites
Superior Suite, Jetted Tub | Bathroom | Shower, designer toiletries, hair dryer, slippers
CinqueSuites Ortigia

CinqueSuites Ortigia

CinqueSuites Ortigia
Ortigia, 0.3 km from Piazza del Duomo
9.2 out of 10, Wonderful, (123)
"Great location for exploring the town. Good size room, had everything we need. Would recommend. "
Canada
Adrian
The price is 2.381.068 ₫
3.022.528 ₫ total
includes taxes & fees
1 Jan - 2 Jan 2026
CinqueSuites Ortigia
Exterior
Ortea Palace Hotel, Sicily, Autograph Collection

Ortea Palace Hotel, Sicily, Autograph Collection

Ortea Palace Hotel, Sicily, Autograph Collection
5.0 star property
Ortigia, 0.7 km from Piazza del Duomo
9.4 out of 10, Exceptional, (252)
"Great location and very friendly staff"
United States
James
The price is 5.803.923 ₫
6.692.454 ₫ total
includes taxes & fees
6 Jan - 7 Jan 2026
Ortea Palace Hotel, Sicily, Autograph Collection
Rooftop terrace
Lanterne Magiche Ortigia

Lanterne Magiche Ortigia

Lanterne Magiche Ortigia
Ortigia, 0.4 km from Piazza del Duomo
9.4 out of 10, Exceptional, (184)
"Staff was wonderful, breakfast was superior."
United States
Joyce
Lanterne Magiche Ortigia
Terrace/patio
Caportigia Boutique Hotel

Caportigia Boutique Hotel

Caportigia Boutique Hotel
5.0 star property
Santa Lucia, 1 km from Piazza del Duomo
9.4 out of 10, Exceptional, (257)
"Fine quality hotel with exceptional service. "
United States
Peter
The price is 3.585.496 ₫
4.252.307 ₫ total
includes taxes & fees
5 Jan - 6 Jan 2026
Caportigia Boutique Hotel
View from property
Elsa d'Ortigia - I TRE ARCHI

Elsa d'Ortigia - I TRE ARCHI

Elsa d'Ortigia - I TRE ARCHI
Ortigia, 0.2 km from Piazza del Duomo
9.4 out of 10, Exceptional, (9)
"Amazing place to stay! Modern, cute, and clean and close to everything! Only thing was water seeping out from the side of the toilet or floor faucet but other than that everything was perfect! "
Canada
Winnie
The price is 2.608.236 ₫
2.973.519 ₫ total
includes taxes & fees
15 Jan - 16 Jan 2026
Elsa d'Ortigia - I TRE ARCHI
Family Twin Room | Hypo-allergenic bedding, down duvets, memory-foam beds, minibar
Joy's BnB Ortigia

Joy's BnB Ortigia

Joy's BnB Ortigia
Ortigia, 0.3 km from Piazza del Duomo
9.4 out of 10, Exceptional, (24)
"Joy's BnB is very well located in one of the main streets of Ortigia, very clean room and the double windows isolate any street noise so you can rest very well, staff kind, and the breakfast included was good, not just coffee and bread."
United States
Raul
Joy's BnB Ortigia
Courtyard
B&B Casa D'Alleri

B&B Casa D'Alleri

B&B Casa D'Alleri
3.0 star property
Ortigia, 0.1 km from Piazza del Duomo
9.2 out of 10, Wonderful, (106)
"Such a beautiful location in the heart of the town! Absolutely stunning property!"
Canada
JOHN DAVID
The price is 3.033.760 ₫
3.458.542 ₫ total
includes taxes & fees
6 Jan - 7 Jan 2026
B&B Casa D'Alleri
Property entrance
Domus Mariae Albergo

Domus Mariae Albergo

Domus Mariae Albergo
3.0 star property
Ortigia, 0.4 km from Piazza del Duomo
9.2 out of 10, Wonderful, (342)
"Lovely staff and unbeatable location! "
United Kingdom
Grace Foggo
The price is 3.768.222 ₫
4.295.755 ₫ total
includes taxes & fees
26 Dec - 27 Dec
Domus Mariae Albergo
Aerial view
Grand Hotel Ortigia Siracusa

Grand Hotel Ortigia Siracusa

Grand Hotel Ortigia Siracusa
5.0 star property
Ortigia, 0.4 km from Piazza del Duomo
9.0 out of 10, Wonderful, (571)
"Great stay!"
United States
Liza
The price is 5.218.740 ₫
6.048.752 ₫ total
includes taxes & fees
7 Jan - 8 Jan 2026
Grand Hotel Ortigia Siracusa
Double Room | Down duvets, minibar, in-room safe, individually decorated
B&B Ninfeo Siracusa

B&B Ninfeo Siracusa

B&B Ninfeo Siracusa
1.2 km from Piazza del Duomo
9.4 out of 10, Exceptional, (33)
"Very good B&B, clean, located near the centre. Very friendly staff!"
United Kingdom
Oksana
The price is 2.722.821 ₫
3.583.030 ₫ total
includes taxes & fees
5 Jan - 6 Jan 2026
B&B Ninfeo Siracusa
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Piazza del Duomo Hotel Reviews

Maniace Boutique Hotel Ortigia UNA Esperienze

Maniace Boutique Hotel Ortigia UNA Esperienze

10/10 Excellent
"All excellent and highly recommended "
Banner 2-night trip
Posted 5 days ago
Maniace Boutique Hotel Ortigia UNA Esperienze
Elsa d'Ortigia

Elsa d'Ortigia

10/10 Excellent
"We decided to stay in Ortiga for 1 night and were very happy we stayed here! Andrea and Maria are perfect hosts, our room was spacious and well designed and the accommodation is perfectly placed to explore the local area. We’d highly recommend Elsa d’Ortiga to anyone thinking of visiting Syracuse. "
Ben 1-night trip
Posted 5 months ago
Elsa d'Ortigia

Hotels near other Piazza del Duomo attractions

Cathedral of Syracuse

4.6/5 (437 reviews)
Learn about the local history of Syracuse with a stop at Cathedral of Syracuse. Wander the seaside in this culturally rich area.
See properties

Palazzo Beneventano del Bosco

You can find out about the history of Syracuse when you stop by Palazzo Beneventano del Bosco. Wander through the beautiful beaches and seaside in this romantic area.
See properties

Frequently asked questions

What's the area like around Piazza del Duomo?
Piazza del Duomo is located in a culturally rich area of Syracuse known for its beautiful beaches and interesting historical sites. If you're looking for a convenient place to stay, take a look at the 1110 hotels and other accommodation options you'll find within a mile.
How many hotels are there near Piazza del Duomo?
Expedia has 1110 hotels and other accommodation options within a mile from Piazza del Duomo.
If I need to cancel the hotel reservation for my stay near Piazza del Duomo, will I receive a refund?
Yes! The majority of room reservations are fully refundable if cancelled prior to the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of your scheduled arrival. If you booked a non-refundable reservation, you might be able to cancel it and get a refund within 24 hours of booking. Put your dates in and click on "Search", then use the "fully refundable" filter to get the best options available near Piazza del Duomo.
What can I see and do near Piazza del Duomo?
You'll want to browse the collections at Arkimedeion Museum, Museum of the Sea of Syracuse and Palazzo Bellomo Regional Gallery. Explore landmarks like Cathedral of Syracuse, Fonte Aretusa and Temple of Apollo. You can enjoy live performances at Syracuse Municipal Theater and Teatro dei Pupi.