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Check availability on Point Loma Business Hotels

Our top choices for Point Loma business-friendly hotels

Lobby
Wyndham Garden San Diego Near SeaWorld

Wyndham Garden San Diego Near SeaWorld

Wyndham Garden San Diego Near SeaWorld
3.0 star property
Point Loma
7.4 out of 10, Good, (4109)
"Room was very clean and staff very pleasant "
Canada
Brian
The price is 2.342.836 ₫
2.692.974 ₫ total
includes taxes & fees
21 Dec - 22 Dec
Wyndham Garden San Diego Near SeaWorld
Exterior
Bay Club Hotel & Marina

Bay Club Hotel & Marina

Bay Club Hotel & Marina
3.5 star property
Point Loma
9.2 out of 10, Wonderful, (3197)
"Great stay and location!"
United States
Jason
The price is 3.056.216 ₫
3.512.967 ₫ total
includes taxes & fees
5 Jan - 6 Jan 2026
Bay Club Hotel & Marina
Standard Room, 2 Queen Beds, Non Smoking, Microwave | Desk, blackout curtains, iron/ironing board, cots/infant beds
Best Western Yacht Harbor Hotel

Best Western Yacht Harbor Hotel

Best Western Yacht Harbor Hotel
2.5 star property
Point Loma
8.6 out of 10, Excellent, (1636)
"The breakfast options were good and the staff were very helpful."
Canada
Gail or Rob
The price is 2.630.031 ₫
3.018.047 ₫ total
includes taxes & fees
21 Dec - 22 Dec
Best Western Yacht Harbor Hotel
Water view
Kona Kai San Diego

Kona Kai San Diego

Kona Kai San Diego
4.0 star property
Point Loma
8.2 out of 10, Very good, (1000)
"had a wonderful time for our honey moon here "
United States
Anna
The price is 3.962.721 ₫
6.134.391 ₫ total
includes taxes & fees
10 Jan - 11 Jan 2026
Kona Kai San Diego
View from room
The Monsaraz San Diego, Tapestry Collection by Hilton

The Monsaraz San Diego, Tapestry Collection by Hilton

The Monsaraz San Diego, Tapestry Collection by Hilton
3.5 star property
Point Loma
8.6 out of 10, Excellent, (623)
"Staff, room cleanliness, location all excellent! I definitely hope to be back soon!"
United States
Wesley
The price is 3.203.105 ₫
3.681.808 ₫ total
includes taxes & fees
26 Dec - 27 Dec
The Monsaraz San Diego, Tapestry Collection by Hilton
Reception
Hampton Inn & Suites by Hilton San Diego SeaWorld

Hampton Inn & Suites by Hilton San Diego SeaWorld

Hampton Inn & Suites by Hilton San Diego SeaWorld
3.0 star property
Point Loma
9.2 out of 10, Wonderful, (423)
"Clean rooms, friendly staff."
United States
KARLA
The price is 2.662.673 ₫
3.060.609 ₫ total
includes taxes & fees
3 Jan - 4 Jan 2026
Hampton Inn & Suites by Hilton San Diego SeaWorld
Exterior
Old Town Inn

Old Town Inn

Old Town Inn
2.5 star property
Point Loma
9.2 out of 10, Wonderful, (1782)
"very confortable hotel nice staff"
United States
Jesus
Old Town Inn
Courtyard view
Courtyard by Marriott San Diego Airport/Liberty Station

Courtyard by Marriott San Diego Airport/Liberty Station

Courtyard by Marriott San Diego Airport/Liberty Station
3.0 star property
Point Loma
9.2 out of 10, Wonderful, (1368)
"Lovely place to stay!"
United States
Helga
The price is 3.818.823 ₫
4.389.546 ₫ total
includes taxes & fees
22 Dec - 23 Dec
Courtyard by Marriott San Diego Airport/Liberty Station
Exterior
Comfort Inn San Diego Airport At The Harbor

Comfort Inn San Diego Airport At The Harbor

Comfort Inn San Diego Airport At The Harbor
3.5 star property
Point Loma
7.8 out of 10, Good, (1189)
"Great location on the bay and close to the airport "
United States
Shawn
The price is 2.114.475 ₫
2.388.194 ₫ total
includes taxes & fees
5 Jan - 6 Jan 2026
Comfort Inn San Diego Airport At The Harbor
Lobby
Comfort Inn Sea World Area

Comfort Inn Sea World Area

Comfort Inn Sea World Area
3.5 star property
Point Loma
8.6 out of 10, Excellent, (3151)
"good hotel "
United States
Lala
The price is 2.237.540 ₫
2.571.941 ₫ total
includes taxes & fees
4 Jan - 5 Jan 2026
Comfort Inn Sea World Area
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Point Loma Hotel Reviews

Hampton Inn & Suites by Hilton San Diego SeaWorld

Hampton Inn & Suites by Hilton San Diego SeaWorld

10/10 Excellent
"Spotless... traveling alone and after staying the night before in the 2nd worse place I have ever stayed - sounds dramatic but I really feared for my life! I could notfeare stayed"
Cynthia 1-night trip
Posted 4 days ago
Hampton Inn & Suites by Hilton San Diego SeaWorld

Frequently asked questions

Why book your business-friendly hotel in Point Loma with Expedia?
Here at Expedia, it's our job to help you track down a suitable stay at the right price. From upmarket, corporate-friendly getaways to affordable motels filled with all the amenities you need, you'll have your next work trip organised in a few simple clicks.
How can I find cheap business-friendly hotels in Point Loma?
Click on the "business friendly" filter, located under the "traveller experience" heading, to find cheap business-friendly hotels in Point Loma. Then fine-tune your search by your preferred hotel star rating and budget. Looking for properties in a less popular neighbourhood is another way to save.