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Check availability on Prague 2 Business Hotels

Our top choices for Prague 2 business-friendly hotels

Couples treatment room(s), massages
Mosaic House Design Hotel

Mosaic House Design Hotel

Mosaic House Design Hotel
4.0 star property
Nové Město
9.8 out of 10, Exceptional, (714)
"Friendly and helpful staff on arrival and when asking for recommendations. Great room with everything needed for a comfortable stay. Spacious bathroom. Nice outside space on the balcony. "
United Kingdom
Andrew
Mosaic House Design Hotel
Lobby
Hermitage Hotel Prague

Hermitage Hotel Prague

Hermitage Hotel Prague
4.5 star property
Prague 2
9.4 out of 10, Exceptional, (1000)
"Location is good; the breakfast is excellent; front desk personnel is super nice and professional"
United States
Wenzhou
The price is 2.201.170 ₫
2.592.650 ₫ total
includes taxes & fees
11 Jan - 12 Jan 2026
Hermitage Hotel Prague
Lobby
Radisson Blu Hotel, Prague

Radisson Blu Hotel, Prague

Radisson Blu Hotel, Prague
5.0 star property
Nové Město
9.0 out of 10, Wonderful, (504)
"Excellent services, well trained staff."
United States
TETIANA
The price is 3.098.685 ₫
3.598.261 ₫ total
includes taxes & fees
11 Jan - 12 Jan 2026
Radisson Blu Hotel, Prague
Property entrance
Hotel Lunik

Hotel Lunik

Hotel Lunik
3.0 star property
Prague 2
8.6 out of 10, Excellent, (324)
"Great location "
United States
Samuel
Hotel Lunik
Luxury Suite | View from room
Le Palais Art Hotel Prague

Le Palais Art Hotel Prague

Le Palais Art Hotel Prague
5.0 star property
Prague 2
9.4 out of 10, Exceptional, (644)
"Lovely staff and facilities will definitely be recommending "
United Kingdom
Sam
The price is 2.108.394 ₫
2.489.261 ₫ total
includes taxes & fees
5 Jan - 6 Jan 2026
Le Palais Art Hotel Prague
Front of property
ibis Praha Wenceslas Square

ibis Praha Wenceslas Square

ibis Praha Wenceslas Square
3.0 star property
Nové Město
8.2 out of 10, Very good, (602)
"From.check-in to check-out was great"
United Kingdom
Barry
The price is 1.569.016 ₫
1.884.638 ₫ total
includes taxes & fees
11 Jan - 12 Jan 2026
ibis Praha Wenceslas Square
Superior Double or Twin Room | Garden view
Royal Court Hotel

Royal Court Hotel

Royal Court Hotel
4.0 star property
Nové Město
8.2 out of 10, Very good, (549)
"Lovely hotel with comfy beds"
United Kingdom
jamie
The price is 1.864.524 ₫
2.215.509 ₫ total
includes taxes & fees
4 Jan - 5 Jan 2026
Royal Court Hotel
Lobby sitting area
Hotel Galileo Prague

Hotel Galileo Prague

Hotel Galileo Prague
4.0 star property
Prague 2
8.8 out of 10, Excellent, (1001)
"Lovely hotel in a safe area. Our room was a bit noisy as it was facing the street with the tram. Breakfast is fine for a city hotel (as you’d expect you won’t get much variety). It is walkable to the main attractions which is good. "
United Kingdom
Lina
The price is 1.863.088 ₫
2.212.167 ₫ total
includes taxes & fees
13 Jan - 14 Jan 2026
Hotel Galileo Prague
Front of property – evening/night
Dancing House – Tančící dům hotel

Dancing House – Tančící dům hotel

Dancing House – Tančící dům hotel
4.0 star property
Nové Město
9.2 out of 10, Wonderful, (437)
"Beautiful hotel with great views of the Vltava river. Walkable to many attractions and restaurants. Staff were helpful. "
United States
Arti
The price is 6.773.801 ₫
7.714.517 ₫ total
includes taxes & fees
2 Jan - 3 Jan 2026
Dancing House – Tančící dům hotel
Reception
THE MANES Boutique Hotel Prague

THE MANES Boutique Hotel Prague

THE MANES Boutique Hotel Prague
4.0 star property
Nové Město
10.0 out of 10, Exceptional, (315)
"Great hotel, clean and comfortable room, excellent, friendly and dedicated staff. Really enjoyed my stay here and already recommended to others."
Canada
Lou
THE MANES Boutique Hotel Prague
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Prague 2 Hotel Reviews

Hotel Unique

Hotel Unique

10/10 Excellent
"This is an exceptional property in an ideal location in Prague. Fantastic restaurants and the National Museum are just a short walk away and the metro/transit connections are easy across the entire city. The affordable price point, clean and spacious rooms, and helpful staff are also a huge plus. I’ve lived in Prague and also visited the city many times for shorter stays, and this is by far the best hotel option."
Todd 2-night trip
Posted 12 days ago
Hotel Unique

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Frequently asked questions

Why book your business-friendly hotel in Prague 2 with Expedia?
Expedia will help you find an ideal business-friendly hotel for your upcoming work trip. From conference spaces and room service to on-site restaurants and more, our stays come with the conveniences you'll need to get the job done.
How can I find cheap business-friendly hotels in Prague 2?
Expedia can help you narrow down your search for cheap business-friendly hotels in Prague 2. Simply go to the "traveller experience" filter and click on "business friendly." This will show you stays with amenities designed to help you work comfortably and effectively, like free WiFi and included breakfast. You can also choose your preferred star rating and budget to keep costs within your price range.