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Check availability on Prague 2 Business Hotels

Our top choices for Prague 2 business-friendly hotels

Front of property
Hermitage Hotel Prague

Hermitage Hotel Prague

Hermitage Hotel Prague
4.5 star property
Prague 2
9.4 out of 10, Exceptional, (1001)
"Location is good; the breakfast is excellent; front desk personnel is super nice and professional"
United States
Wenzhou
The price is 2.115.563 ₫
2.496.139 ₫ total
includes taxes & fees
11 Jan - 12 Jan 2026
Hermitage Hotel Prague
Reception
The Emblem Prague Hotel - Preferred Hotels & Resorts

The Emblem Prague Hotel - Preferred Hotels & Resorts

The Emblem Prague Hotel - Preferred Hotels & Resorts
5.0 star property
Prague City Center
9.4 out of 10, Exceptional, (1001)
"Ideal location for exploring Prague Old Town, Christmas Market and other sights."
United States
Mika
The price is 5.804.236 ₫
6.627.302 ₫ total
includes taxes & fees
4 Jan - 5 Jan 2026
The Emblem Prague Hotel - Preferred Hotels & Resorts
View from property
Hotel Leon D´Oro

Hotel Leon D´Oro

Hotel Leon D´Oro
4.0 star property
Prague City Center
9.4 out of 10, Exceptional, (1304)
"Great location, spacious room, very clean and good breakfast. "
United States
Gina
Hotel Leon D´Oro
Exterior
K+K Hotel Central Prague

K+K Hotel Central Prague

K+K Hotel Central Prague
4.0 star property
Prague City Center
9.2 out of 10, Wonderful, (1046)
"Hotel & breakfast "
United Kingdom
Delyth Lloyd
The price is 2.459.464 ₫
2.882.590 ₫ total
includes taxes & fees
18 Jan - 19 Jan 2026
K+K Hotel Central Prague
Exterior
Mosaic House Design Hotel

Mosaic House Design Hotel

Mosaic House Design Hotel
4.0 star property
Nové Město
9.8 out of 10, Exceptional, (718)
"Stupendous hotel, staff, attention to detail, the lot."
United Kingdom
Patricia
Mosaic House Design Hotel
Bar (on property)
Radisson Blu Hotel, Prague

Radisson Blu Hotel, Prague

Radisson Blu Hotel, Prague
5.0 star property
Nové Město
9.0 out of 10, Wonderful, (506)
"Excellent services, well trained staff."
United States
TETIANA
The price is 3.073.789 ₫
3.569.352 ₫ total
includes taxes & fees
11 Jan - 12 Jan 2026
Radisson Blu Hotel, Prague
Exterior
ibis Praha Wenceslas Square

ibis Praha Wenceslas Square

ibis Praha Wenceslas Square
3.0 star property
Nové Město
8.2 out of 10, Very good, (602)
"From.check-in to check-out was great"
United Kingdom
Barry
The price is 1.476.369 ₫
1.780.241 ₫ total
includes taxes & fees
11 Jan - 12 Jan 2026
ibis Praha Wenceslas Square
Meeting facility
Residence Jecna

Residence Jecna

Residence Jecna
4.0 star property
Nové Město
9.2 out of 10, Wonderful, (96)
"The staff is friendly "
Canada
Anita
The price is 1.488.265 ₫
1.793.414 ₫ total
includes taxes & fees
4 Jan - 5 Jan 2026
Residence Jecna
Breakfast, lunch, dinner served; garden views
Novotel Praha Wenceslas Square

Novotel Praha Wenceslas Square

Novotel Praha Wenceslas Square
4.0 star property
Nové Město
8.6 out of 10, Excellent, (1000)
"Excellent place to stay, we enjoyed everything about this place."
Canada
Tony
The price is 2.036.371 ₫
2.407.443 ₫ total
includes taxes & fees
18 Jan - 19 Jan 2026
Novotel Praha Wenceslas Square
Reception
Hotel Lunik

Hotel Lunik

Hotel Lunik
3.0 star property
Prague 2
8.6 out of 10, Excellent, (325)
"Great location "
United States
Samuel
Hotel Lunik
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Prague 2 Hotel Reviews

Hotel Unique

Hotel Unique

10/10 Excellent
"This is an exceptional property in an ideal location in Prague. Fantastic restaurants and the National Museum are just a short walk away and the metro/transit connections are easy across the entire city. The affordable price point, clean and spacious rooms, and helpful staff are also a huge plus. I’ve lived in Prague and also visited the city many times for shorter stays, and this is by far the best hotel option."
Todd 2-night trip
Posted 3 weeks ago
Hotel Unique

Frequently asked questions

Why book your business-friendly hotel in Prague 2 with Expedia?
Expedia will help you find an ideal business-friendly hotel for your upcoming work trip. From conference spaces and room service to on-site restaurants and more, our stays come with the conveniences you'll need to get the job done.
How can I find cheap business-friendly hotels in Prague 2?
Expedia can help you narrow down your search for cheap business-friendly hotels in Prague 2. Simply go to the "traveller experience" filter and click on "business friendly." This will show you stays with amenities designed to help you work comfortably and effectively, like free WiFi and included breakfast. You can also choose your preferred star rating and budget to keep costs within your price range.

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