Search Hotels in Regis, Denver

Start date: Check-in selected.
To Date
End date: Check-out

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
15 Dec - 16 Dec
Tomorrow
16 Dec - 17 Dec
This weekend
19 Dec - 21 Dec
Next weekend
26 Dec - 28 Dec

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Regis hotels

Terrace/patio
Motel 6 Denver, CO – Downtown

Motel 6 Denver, CO – Downtown

Motel 6 Denver, CO – Downtown
2.0 star property
Regis
7.4 out of 10, Good, (1140)
"Enjoy the stay"
United States
Jose
The price is 1.374.278 ₫
1.590.522 ₫ total
includes taxes & fees
23 Dec - 24 Dec
Motel 6 Denver, CO – Downtown
Exterior
Sonesta Denver Downtown

Sonesta Denver Downtown

Sonesta Denver Downtown
4.0 star property
Downtown Denver, 6.7 km from Regis
8.4 out of 10, Very good, (2267)
"Great staff, clean, nice rooms and great location"
United States
Christopher
The price is 2.604.393 ₫
3.014.584 ₫ total
includes taxes & fees
22 Dec - 23 Dec
Sonesta Denver Downtown
Lobby sitting area
Hilton Denver City Center

Hilton Denver City Center

Hilton Denver City Center
4.0 star property
Downtown Denver, 6.5 km from Regis
8.6 out of 10, Excellent, (1166)
"Amazing room, great staff! "
United States
Ragavendra
The price is 2.832.015 ₫
3.278.056 ₫ total
includes taxes & fees
3 Jan - 4 Jan 2026
Hilton Denver City Center
Exterior
Home2 Suites by Hilton Denver Downtown Convention Center

Home2 Suites by Hilton Denver Downtown Convention Center

Home2 Suites by Hilton Denver Downtown Convention Center
3.0 star property
Downtown Denver, 6.4 km from Regis
9.0 out of 10, Wonderful, (2065)
"Great hotel"
United States
Rafael
The price is 2.134.024 ₫
2.470.131 ₫ total
includes taxes & fees
22 Dec - 23 Dec
Home2 Suites by Hilton Denver Downtown Convention Center
Meeting facility
Renaissance Denver Hotel & Conference Center

Renaissance Denver Hotel & Conference Center

Renaissance Denver Hotel & Conference Center
4.0 star property
12.1 km from Regis
8.4 out of 10, Very good, (1736)
"We enjoyed our stay. "
United States
Rashanelle
The price is 2.420.704 ₫
2.801.964 ₫ total
includes taxes & fees
11 Jan - 12 Jan 2026
Renaissance Denver Hotel & Conference Center
Exterior
Grand Hyatt Denver

Grand Hyatt Denver

Grand Hyatt Denver
4.5 star property
Downtown Denver, 6.6 km from Regis
9.4 out of 10, Exceptional, (1484)
"Hotel is very inviting and rooms extremely comfortable. "
United States
Julie K
The price is 4.445.883 ₫
5.146.109 ₫ total
includes taxes & fees
1 Jan - 2 Jan 2026
Grand Hyatt Denver
Restaurant
AC Hotel by Marriott Denver Downtown

AC Hotel by Marriott Denver Downtown

AC Hotel by Marriott Denver Downtown
3.5 star property
Downtown Denver, 6.4 km from Regis
9.0 out of 10, Wonderful, (1003)
"Clean room, easy checkin , great location "
United States
Heather
The price is 2.885.111 ₫
3.339.515 ₫ total
includes taxes & fees
2 Jan - 3 Jan 2026
AC Hotel by Marriott Denver Downtown
Room, 1 King Bed, Corner | Premium bedding, down duvets, desk, laptop workspace
Hyatt Place Denver Downtown

Hyatt Place Denver Downtown

Hyatt Place Denver Downtown
3.5 star property
Downtown Denver, 6.7 km from Regis
9.0 out of 10, Wonderful, (2993)
"Rooms & Lobby clean and staff very helpful"
United States
Barbara
The price is 2.693.837 ₫
3.118.116 ₫ total
includes taxes & fees
3 Jan - 4 Jan 2026
Hyatt Place Denver Downtown
Exterior
Magnolia Hotel Denver, A Tribute Portfolio Hotel

Magnolia Hotel Denver, A Tribute Portfolio Hotel

Magnolia Hotel Denver, A Tribute Portfolio Hotel
4.0 star property
Downtown Denver, 6.3 km from Regis
8.8 out of 10, Excellent, (1428)
"Great hotel! Friendly staff, clean and very comfortable bed!"
United States
Amy
The price is 2.596.107 ₫
3.004.995 ₫ total
includes taxes & fees
22 Dec - 23 Dec
Magnolia Hotel Denver, A Tribute Portfolio Hotel
Lobby
La Quinta Inn & Suites by Wyndham Littleton/Red Rocks

La Quinta Inn & Suites by Wyndham Littleton/Red Rocks

La Quinta Inn & Suites by Wyndham Littleton/Red Rocks
3.0 star property
21.2 km from Regis
9.4 out of 10, Exceptional, (1240)
"Excellent accommodations and the staff were amazing!"
United States
Michael
The price is 2.557.040 ₫
2.736.191 ₫ total
includes taxes & fees
14 Jan - 15 Jan 2026
La Quinta Inn & Suites by Wyndham Littleton/Red Rocks
Snack bar
Tru By Hilton Denver Downtown Convention Center

Tru By Hilton Denver Downtown Convention Center

Tru By Hilton Denver Downtown Convention Center
2.5 star property
Downtown Denver, 6.3 km from Regis
8.8 out of 10, Excellent, (1777)
"Clean room, great downtown location and excellent breakfast."
United States
Dan
The price is 2.083.514 ₫
2.411.668 ₫ total
includes taxes & fees
22 Dec - 23 Dec
Tru By Hilton Denver Downtown Convention Center
Exterior
Atwell Suites Denver Airport Tower Road by IHG

Atwell Suites Denver Airport Tower Road by IHG

Atwell Suites Denver Airport Tower Road by IHG
3.0 star property
23.3 km from Regis
9.2 out of 10, Wonderful, (1186)
"Great place to stay! I would stay there again witout any doubt."
United States
Isanna
The price is 2.420.244 ₫
2.801.431 ₫ total
includes taxes & fees
22 Dec - 23 Dec
Atwell Suites Denver Airport Tower Road by IHG
Lobby
Hampton Inn & Suites Denver-Downtown

Hampton Inn & Suites Denver-Downtown

Hampton Inn & Suites Denver-Downtown
3.0 star property
Uptown, 6.9 km from Regis
8.6 out of 10, Excellent, (2248)
"The staff, the rooms, the location and tje breakfast 10+"
United States
Judi
The price is 2.083.514 ₫
2.411.668 ₫ total
includes taxes & fees
22 Dec - 23 Dec
Hampton Inn & Suites Denver-Downtown
Bar (on property)
Hilton Garden Inn Denver Union Station, CO

Hilton Garden Inn Denver Union Station, CO

Hilton Garden Inn Denver Union Station, CO
3.5 star property
LoDo, 5.1 km from Regis
9.0 out of 10, Wonderful, (2110)
"Great short stay"
United States
Nicholas
The price is 2.504.426 ₫
2.898.873 ₫ total
includes taxes & fees
22 Dec - 23 Dec
Hilton Garden Inn Denver Union Station, CO
Rooftop terrace
Hyatt Centric Downtown Denver

Hyatt Centric Downtown Denver

Hyatt Centric Downtown Denver
4.0 star property
Downtown Denver, 6.3 km from Regis
9.0 out of 10, Wonderful, (2083)
"Great hotel"
United States
Miguel
The price is 2.604.888 ₫
3.015.158 ₫ total
includes taxes & fees
21 Dec - 22 Dec
Hyatt Centric Downtown Denver
Free daily buffet breakfast
Sleep Inn & Suites Denver International Airport

Sleep Inn & Suites Denver International Airport

Sleep Inn & Suites Denver International Airport
2.5 star property
23.4 km from Regis
8.6 out of 10, Excellent, (1589)
"Very clean, comfortable, very good location in relation to the airport, good breakfast for the value!"
United States
Giampaolo
The price is 2.201.896 ₫
2.548.695 ₫ total
includes taxes & fees
17 Dec - 18 Dec
Sleep Inn & Suites Denver International Airport
Concierge desk
Hyatt House Denver Downtown

Hyatt House Denver Downtown

Hyatt House Denver Downtown
3.5 star property
Downtown Denver, 6.7 km from Regis
9.0 out of 10, Wonderful, (1013)
"Very clean, friendly staff, great location and breakfast."
United States
María
The price is 2.547.002 ₫
2.948.155 ₫ total
includes taxes & fees
5 Jan - 6 Jan 2026
Hyatt House Denver Downtown
Dining
Origin Red Rocks, a Wyndham Hotel

Origin Red Rocks, a Wyndham Hotel

Origin Red Rocks, a Wyndham Hotel
3.5 star property
16.7 km from Regis
9.0 out of 10, Wonderful, (1353)
"Easy check in, very clean, close to red rocks. "
United States
Jacqueline
The price is 2.660.953 ₫
3.020.181 ₫ total
includes taxes & fees
4 Jan - 5 Jan 2026
Origin Red Rocks, a Wyndham Hotel
Exterior
La Quinta Inn & Suites by Wyndham Denver Airport DIA

La Quinta Inn & Suites by Wyndham Denver Airport DIA

La Quinta Inn & Suites by Wyndham Denver Airport DIA
3.0 star property
23.4 km from Regis
7.8 out of 10, Good, (3571)
"Room was clean and staff was friendly! I will definitely be staying here again "
United States
Sarah
The price is 2.024.324 ₫
2.343.154 ₫ total
includes taxes & fees
23 Dec - 24 Dec
La Quinta Inn & Suites by Wyndham Denver Airport DIA
Restaurant
Vīb Hotel by Best Western Denver RiNo

Vīb Hotel by Best Western Denver RiNo

Vīb Hotel by Best Western Denver RiNo
3.0 star property
River North Art District, 6 km from Regis
9.2 out of 10, Wonderful, (796)
"great room and staff"
United States
RAY
The price is 2.884.563 ₫
3.338.884 ₫ total
includes taxes & fees
22 Dec - 23 Dec
Vīb Hotel by Best Western Denver RiNo
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Where to stay in Regis

Find the best Regis areas for the activities you enjoy most.

Downtown Denver

Gourmet restaurants great entertainment and top sights from Paramount Theater to 16th Street – discover Downtown Denver, a destination also famous for its shopping.

Cherry Creek

Abundant dining options and stunning river views are well-reviewed features of Cherry Creek. Make a stop by top sights like Cherry Creek Shopping Center while you're exploring the area.

LoDo

Visitors often come to LoDo for its abundant dining options, but many stay to explore sights like Union Station and McGregor Square. Getting around the area on the metro is easy if you take a ride at Union Station-Coors Field-16th St. Mall Station.

Denver Tech Center

Known for its ample dining options and great live music, there's plenty to explore in Denver Tech Center. You can visit top attractions like The Landmark Theatre Greenwood Village and Fiddler's Green Amphitheatre, and jump on the metro at Orchard Station or Arapahoe at Village Center Station to see more of the city.

Highlands Ranch

Highlands Ranch is known for its abundant dining options, and you can plan a trip to South Suburban Sports Complex and Chatfield State Park while you're in town.

Top Regis Hotel Reviews

Explore a world of travel with Expedia

Frequently asked questions

What is Regis like?
Regis is a neighbourhood that travellers like for its jazz scene, golf courses and university setting. Are you looking for Regis travel tips? Make sure that you visit Clear Creek and Willis Case Golf Course while you're in the neighbourhood.
How many hotels will I be able to find in Regis?
When you want to put your feet up after a day of exploring the sights in Denver, you can choose from 10 Expedia hotels and other accommodation options in Regis.
If I need to cancel my hotel reservation in Regis, will I receive a refund?
Yes, you'll find most hotel room reservations are fully refundable provided that you cancel prior to the hotel's cancellation deadline, which is often 24 or 48 hours before the scheduled arrival. If you booked a non-refundable reservation, it might still be possible to cancel it and be given a refund within 24 hours of booking. Add your dates and click on "Search", then you can use the "fully refundable" filter to view the best options available in Regis.
What can I see and do in this Denver neighbourhood?
A few attractions you might want to check out while you're in Regis are Clear Creek and Willis Case Golf Course. While you're out sightseeing in Denver, make sure that you visit other sights such as Lakeside Amusement Park or Germinal Stage Denver.