San Antonio Holidays

Book a Hotel + Flight or Car together to unlock savings

Where to stay in San Antonio

Find the best San Antonio areas and neighborhoods for the activities you enjoy most. Learn more about San Antonio
A historic town with terracotta-roofed buildings, a prominent bell tower, and a sign for 'Edificio Domingo Guevara Yanez'.

Cusco Historic Center

6 out of top 10 points of interest in this area
4.5/5(63 area reviews)

Cusco Historic Center is known for its popular shops, and with sights like Plaza de Armas and Santa Catalina Convent, you won't get bored spending a day wandering around this part of Cusco.

Find hotels in Cusco Historic Center

Top hotels in San Antonio

Kantu Hotel

Kantu Hotel

3 out of 5
calle chaparro 121 Cusco Cuzco
Fully refundable
The price is 1.780.254 ₫ per night from 12 Jul to 13 Jul
1.780.254 ₫
1.780.254 ₫ total
12 Jul - 13 Jul
9.2/10 Wonderful! (516 reviews)
"Hotel de lujo, muy limpio, buena atención del personal pendiente de lo que necesitaba si volviera al Cuzco sin dudarlo me volvería a hospedar aqui"

Reviewed on 3 Jul 2026

Kantu Hotel
Hampton By Hilton Cusco

Hampton By Hilton Cusco

4 out of 5
Tullumayu Avenue 227 Cusco NULL
The price is 2.906.607 ₫ per night from 2 Aug to 3 Aug
2.906.607 ₫
3.197.268 ₫ total
2 Aug - 3 Aug
9.4/10 Exceptional! (62 reviews)
"This is a great hotel to stay of you're in Cusco. The staff is very attentive, the property is clean and smells soooo good. We arrived before check in and they had coca and munya tea ready for guests, in case you were struggling with the altitude. The breakfast options are very good too and though ..."

Reviewed on 3 Jul 2026

Hampton By Hilton Cusco
Palacio del Inka, A Luxury Collection Hotel by Marriott

Palacio del Inka, A Luxury Collection Hotel by Marriott

5 out of 5
Plazoleta Santo Domingo No 259 Cusco Cusco
Fully refundableReserve now, pay when you stay
The price is 8.695.103 ₫ per night from 27 Jul to 28 Jul
8.695.103 ₫
10.652.783 ₫ total
27 Jul - 28 Jul
9.6/10 Exceptional! (1,000 reviews)
"Excellent staff greeted us right away. We were able to grab a very nice lunch in the patio area after a long flight. Room in excellent condition. We loved the tour of hotel with an Inca show at end and tried the Pisco Sour class. Breakfast buffet cannot be beat. We went late the first day and it ..."

Reviewed on 30 Jun 2026

Palacio del Inka, A Luxury Collection Hotel by Marriott
See all 1,825 properties in San Antonio
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a San Antonio holiday package cost?
We make it simple to travel the world, with San Antonio packages starting from as little as . You'll have the flexibility to combine your preferred hotels, airlines and car rental. For the ultimate escape, why not add a few activities and tours to your travel itinerary?
How do I get a cheap travel package to San Antonio?
Crafting your own San Antonio holiday package with Expedia is one of the easiest ways to save. We offer more than 550 partner airlines and 1null000null000 hotel options spread across the globe. With such a fabulous range to pick from, you'll have no trouble pulling together your perfect getaway.
Where should I stay in San Antonio?
With fascinating attractions such as Regional Hospital of Cusco and National University of Saint Anthony the Abbot in Cuzco in this neighbourhood, see if you can find a hotel near either of them. Real Plaza Cusco is another sight that visitors flock to.
What are the top hotels in San Antonio?
If it's comfort and convenience you're seeking, you can't go past Apart Las Margaritas Hotel. Spend your nights relaxing here and your days roaming around San Antonio's best sights.
How far in advance should I book my San Antonio holiday?
While not all air carriers advertise tickets early, you can normally start comparing international fares on Expedia up to a year in advance. This is the time you'll bag some incredible deals. If you've left things to the last minute, you might get lucky. Low prices sometimes emerge a few weeks before departure.
What does an Expedia San Antonio travel package include?
With Expedia, you can choose a combination of car rentals, hotels and flights to build your perfect San Antonio package. Once you've made your booking, you can add on fun stuff like sightseeing tours and activities. Remember, the more you bundle, the bigger the savings!
What should I know before booking a San Antonio travel package?
Bundling your bookings into a San Antonio holiday package is the easiest way to organise your trip. Not only that, you'll save big just for combining your hotels, flights and car rentals. Once you've booked, why not add on an activity or a tour?
Can I choose my airline with a San Antonio Expedia holiday package?
You can, and with more than 550 airlines to select from throughout the world, you're not short on choice. Look through the available options and see which airline best fits your budget and needs.
If I'm not able to travel, can I cancel my San Antonio holiday package?
Plans can change unexpectedly, so yes, you can. You may be able to cancel or change your San Antonio holiday package at no cost within 24 hours of booking. For older bookings, you can still cancel and rebook, but your car rental company, hotel or airline may charge a fee. Looking for more information? Check out our Customer Service Portal. We're here to help make sure your trip goes off without a hitch.