Photo by Felipe Romero Serrano

Search Business Hotels in San Diego

Start date: Check-in selected.
To Date
End date: Check-out

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on San Diego Business Hotels

Our top choices for San Diego business-friendly hotels

Courtyard
Bastión Luxury Hotel

Bastión Luxury Hotel

Bastión Luxury Hotel
4.5 star property
Cartagena Walled City
9.6 out of 10, Exceptional, (1002)
"Beautiful property "
Canada
Linda
The price is 7.034.347 ₫
7.034.347 ₫ total
15 Dec - 16 Dec
Bastión Luxury Hotel
Restaurant
Hotel Boutique Bovedas de Santa Clara By Accor

Hotel Boutique Bovedas de Santa Clara By Accor

Hotel Boutique Bovedas de Santa Clara By Accor
4.0 star property
Cartagena Walled City
9.0 out of 10, Wonderful, (298)
"Room was spacious, clean and very well appointed. Beds were comfortable and the supplied toiletries were amazing. Employees are the example of how hospitality staff should be. Loved our stay. Thank you!"
Canada
Eugenia
The price is 7.390.857 ₫
7.390.857 ₫ total
16 Dec - 17 Dec
Hotel Boutique Bovedas de Santa Clara By Accor
Sun deck
Apartamento de Lujo Virrey de Eslava

Apartamento de Lujo Virrey de Eslava

Apartamento de Lujo Virrey de Eslava
3.5 star property
Cartagena Walled City
6.8 out of 10, (10)
"American man, Colombian wife, 2 American teenage boys: Overall the apartment was very nice and we enjoyed our stay. Very clean and within walking distance to the entire city and beaches. Nice pool within the complex as well. It was quiet at night even though you're in the heart of the city walls. A few minor miscommunications with management, but nothing that impacted our stay in a negative manner. Overall, very happy with this apartment. "
United States
Brett
Apartamento de Lujo Virrey de Eslava
Exterior
Sofitel Legend Santa Clara Cartagena

Sofitel Legend Santa Clara Cartagena

Sofitel Legend Santa Clara Cartagena
5.0 star property
Cartagena Walled City
9.6 out of 10, Exceptional, (1001)
"Great experience Hotel,Room, Service"
United States
Eduardo
The price is 11.214.904 ₫
11.214.904 ₫ total
19 Dec - 20 Dec
Sofitel Legend Santa Clara Cartagena
Outdoor pool
Varanasi Hotel Boutique

Varanasi Hotel Boutique

Varanasi Hotel Boutique
3.0 star property
Marbella
9.2 out of 10, Wonderful, (578)
"room clean all good"
United States
Steven
The price is 2.905.781 ₫
2.905.781 ₫ total
3 Jan - 4 Jan 2026
Varanasi Hotel Boutique
Outdoor pool, free pool cabanas, pool loungers
InterContinental Cartagena De Indias by IHG

InterContinental Cartagena De Indias by IHG

InterContinental Cartagena De Indias by IHG
4.0 star property
Bocagrande
9.4 out of 10, Exceptional, (1361)
"Very nice hotel with great breakfast. "
United States
Joshua
The price is 4.794.338 ₫
4.794.338 ₫ total
13 Dec - 14 Dec
InterContinental Cartagena De Indias by IHG
2 restaurants, lunch served
Hyatt Regency Cartagena

Hyatt Regency Cartagena

Hyatt Regency Cartagena
4.5 star property
Bocagrande
9.4 out of 10, Exceptional, (1429)
"The hotel was beautiful. The service was great. "
United States
Carolyn
The price is 5.040.776 ₫
5.040.776 ₫ total
12 Dec - 13 Dec
Hyatt Regency Cartagena
2 bars/lounges
Wyndham Garden Cartagena

Wyndham Garden Cartagena

Wyndham Garden Cartagena
3.5 star property
Marbella
8.8 out of 10, Excellent, (1400)
"We would like to thank you for the great service. We really enjoyed our stay."
United States
Acuario
The price is 2.820.199 ₫
2.820.199 ₫ total
12 Dec - 13 Dec
Wyndham Garden Cartagena
Terrace/patio
Hotel Casa Canabal by Faranda Boutique

Hotel Casa Canabal by Faranda Boutique

Hotel Casa Canabal by Faranda Boutique
4.0 star property
Cartagena Walled City
9.2 out of 10, Wonderful, (482)
"The staff were exceptional and the room/location were wonderful. We only wish we could have stayed longer. "
United States
Christopher
The price is 3.298.611 ₫
3.298.611 ₫ total
18 Dec - 19 Dec
Hotel Casa Canabal by Faranda Boutique
Interior
Leones de Alba Hotel Boutique

Leones de Alba Hotel Boutique

Leones de Alba Hotel Boutique
5.0 star property
Cartagena Walled City
9.4 out of 10, Exceptional, (62)
"Super friendly helpful staff, room was really clean, would definitely stay here again."
Canada
Peter
The price is 4.115.558 ₫
4.115.558 ₫ total
12 Dec - 13 Dec
Leones de Alba Hotel Boutique
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top San Diego Hotel Reviews

Explore a world of travel with Expedia

Frequently asked questions

How much do business-friendly hotels in San Diego cost?
Business-friendly hotels in San Diego range between 2.820.199 ₫ and 11.214.904 ₫ per night. This means you can reserve a property with conveniences like WiFi and conference rooms at a price that's easy on your wallet. These prices were available on Expedia within the past 7 days, for a hotel booking with a check-in date within the next year. Prices reflect current offers and availability is subject to change. Additional terms may apply.
What are the best business-friendly hotels in San Diego?
Many corporate travellers recommend Hotel Quadrifolio. This 4.5-stars stay offers amenities such as individually decorated rooms and a terrace. Alfiz Hotel Boutique is another sought-after option. It has a 3-stars rating and conveniences like a garden and a Champagne service. You can pick from multiple business-friendly hotels in San Diego that have a total average guest review rating of 8.9.
How many business-friendly hotels are there in San Diego?
San Diego offers 25 hotels that accommodate business travellers. Whether you're seeking a central location or conveniences such as dependable WiFi and conference rooms, you'll find everything you need with Expedia.
What are the best cheap business-friendly hotels in San Diego?
Business-friendly hotels in San Diego start from only 2.820.199 ₫ per night, so your official work trip doesn't have to cost a fortune. Hotel Casa Centenario is an affordable option that features lots of amenities, like a terrace and a rooftop terrace. Hostel Casablanca 4130 is another budget stay that's popular with corporate guests. Conveniences here include a barbecue grill and a rooftop terrace. If you're eager to make room for some sightseeing during your business trip to San Diego, there are many popular and free attractions to put on your itinerary. Bocagrande Beach and Playa Manzanillo are worth stopping by. This price was available on Expedia within the past 7 days, for a hotel booking with a check-in date within the next year. Prices reflect current offers and availability is subject to change. Additional terms may apply.
Are there any family-friendly hotels in San Diego that are also business friendly?
If you're holidaying with the family in San Diego but also need to work remotely, look up Hotel Quadrifolio. This 4.5-stars escape features amenities such as complimentary breakfast and housekeeping services. Casablanca Belle & Boutique is another property that's perfect for both corporate and leisure guests. It has a 4-stars rating and conveniences such as complimentary breakfast and a barbecue grill. San Diego has no shortage of family-friendly attractions to explore when you're done with work. Take the kids on an excursion to Bocagrande Beach and Playa Manzanillo.
Are there any 5-star business-friendly hotels in San Diego?
San Diego has some marvellous 5-star accommodation for corporate guests. Enjoy a little indulgence after a day of meetings at Sofitel Legend Santa Clara Cartagena. Amenities at this business-friendly escape, around 0.16 km from central San Diego, include a pillow menu and spa facilities. Another high-end property that has everything you need for a work trip is Charleston Santa Teresa Cartagena. It offers a rooftop terrace and beauty services and is 2 km from the downtown area.
Why book your business-friendly hotel in San Diego with Expedia?
Expedia will help you find a suitable business-friendly hotel when work takes you out of town. From conference spaces and room service to on-site cafés and restaurants, our properties have the things you need to get the job done.
How can I find cheap business-friendly hotels in San Diego?
Click on the "business friendly" filter, listed just under the "traveller experience" heading, to find cheap business-friendly hotels in San Diego. Then narrow your search by your per-night budget. Choosing a property outside the city centre is another good way to save.
What is there to do in San Diego near my business-friendly hotel?
Whatever you love doing, San Diego has plenty to keep you going. Bocagrande Beach, Playa Manzanillo and La Boquilla Beach are on most travellers' sightseeing itineraries. Don't forget about San Felipe de Barajas Castle, Marbella Beach and Castillo Grande Beach either. With Expedia's business-friendly hotel deals, you can see even more terrific attractions like these with the money you save.