Search Hotels in San Diego, Medellin

Start date: Check-in selected.
To Date
End date: Check-out
  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Filter by

Guest rating
Guest rating
Star rating

Our top choices for San Diego hotels

Metropolitan Living by HOUSY

Metropolitan Living by HOUSY
4.0 star property
San Diego
9.4 out of 10, Exceptional, (23)
"Great location."
United States
Nekitta
The price is 1.186.212 ₫
1.976.142 ₫ total
20 Dec - 21 Dec
Metropolitan Living by HOUSY

Mi Hotel Sandiego

Mi Hotel Sandiego
3.5 star property
San Diego
8.8 out of 10, Excellent, (396)
"The property is clean safe and good food"
United States
Paul
Mi Hotel Sandiego

La Quinta by Wyndham Medellin

La Quinta by Wyndham Medellin
3.5 star property
San Diego
8.8 out of 10, Excellent, (1002)
"Breakfast, clean room and room service amazing!"
United States
Lyandra Jiliénne
The price is 2.215.754 ₫
2.215.754 ₫ total
12 Jan - 13 Jan 2026
La Quinta by Wyndham Medellin

Bio 26 Apartments

Bio 26 Apartments
4.5 star property
San Diego
The price is 3.649.477 ₫
4.571.062 ₫ total
17 Jan - 18 Jan 2026
Bio 26 Apartments

Hotel Attic 33

Hotel Attic 33
3.0 star property
Laureles, 2.2 km from San Diego
9.8 out of 10, Exceptional, (8)
"Was great, very recommended for a quick trip. "
United States
jorge
The price is 1.262.048 ₫
1.262.048 ₫ total
11 Jan - 12 Jan 2026
Hotel Attic 33

Hotel Once22

Hotel Once22
3.0 star property
10.5 km from San Diego
9.4 out of 10, Exceptional, (26)
"Great stay as usual, wonderful service from check-in to check-out"
United States
Al
The price is 1.390.861 ₫
1.390.861 ₫ total
20 Dec - 21 Dec
Hotel Once22

4 Sur Hotel

4 Sur Hotel
3.0 star property
Guayabal, 3.3 km from San Diego
9.4 out of 10, Exceptional, (199)
"Very good place to enjoy the stay"
United States
Alberto
The price is 1.793.437 ₫
1.875.189 ₫ total
19 Dec - 20 Dec
4 Sur Hotel

Hotel Nutibara

Hotel Nutibara
3.0 star property
La Candelaria, 2.4 km from San Diego
7.4 out of 10, Good, (538)
"Good, staff very friendley. "
United States
Robert
The price is 2.188.913 ₫
2.188.913 ₫ total
16 Jan - 17 Jan 2026
Hotel Nutibara

Hotel Madeiro

Hotel Madeiro
3.0 star property
Zona Rosa, 2.3 km from San Diego
8.4 out of 10, Very good, (245)
"Incredible location and my time at Madeiro was very nice. I recommend everyone to stay here. "
United States
David
The price is 1.622.371 ₫
1.622.371 ₫ total
24 Dec - 25 Dec
Hotel Madeiro

Hotel Lleras 10

Hotel Lleras 10
3.0 star property
Zona Rosa, 2.3 km from San Diego
8.2 out of 10, Very good, (329)
"Place was quet clen good breakfast all very well"
United States
Andre
Hotel Lleras 10

Firenze Lofts

Firenze Lofts
3.0 star property
La América, 4.2 km from San Diego
9.6 out of 10, Exceptional, (375)
"Nice property and great staff"
United States
Daniel Eduardo
Firenze Lofts

The Host Medellin Only Adults

The Host Medellin Only Adults
3.0 star property
Astorga, 2.5 km from San Diego
10.0 out of 10, Exceptional, (12)
"Great ambience and room, excellent breakfast "
United States
Shailendra
The price is 5.591.845 ₫
5.591.845 ₫ total
20 Dec - 21 Dec
The Host Medellin Only Adults

Hotel San Pedro del Fuerte

Hotel San Pedro del Fuerte
3.0 star property
La América, 4.5 km from San Diego
8.6 out of 10, Excellent, (301)
"The property was clean and the staff were very helpful and professional. "
Australia
Luis
Hotel San Pedro del Fuerte

The Somos Beats Hotel & Rooftop

The Somos Beats Hotel & Rooftop
3.5 star property
Zona Rosa, 2.3 km from San Diego
8.4 out of 10, Very good, (344)
"Great stay no complaints at all "
United States
Casey
The price is 2.158.148 ₫
2.158.148 ₫ total
22 Dec - 23 Dec
The Somos Beats Hotel & Rooftop

Moa Select

Moa Select
3.0 star property
Belen, 3.8 km from San Diego
9.4 out of 10, Exceptional, (198)
"Great place"
United States
Cody
The price is 1.487.893 ₫
1.487.893 ₫ total
12 Jan - 13 Jan 2026
Moa Select

Hotel El Portón de San Joaquín

Hotel El Portón de San Joaquín
3.0 star property
Laureles, 2.8 km from San Diego
9.0 out of 10, Wonderful, (260)
"Great affordable hotel and centrally located in Laureles."
United States
Alexander
Hotel El Portón de San Joaquín

Hotel Living 35 Suites

Hotel Living 35 Suites
4.0 star property
La América, 5.1 km from San Diego
9.6 out of 10, Exceptional, (109)
"Excellent place to relax, quiet surroundings and good service "
United States
Royte
Hotel Living 35 Suites

The Morgana Poblado Suites Hotel

The Morgana Poblado Suites Hotel
3.5 star property
Buenos Aires, 1.6 km from San Diego
8.8 out of 10, Excellent, (861)
"Staff always super nice and very approachable"
United States
Hector
The Morgana Poblado Suites Hotel

Holiday Inn Express Medellin by IHG

Holiday Inn Express Medellin by IHG
3.0 star property
Alejandria, 3.2 km from San Diego
8.8 out of 10, Excellent, (923)
"Great!"
United States
Kelly
The price is 2.422.452 ₫
2.817.417 ₫ total
20 Dec - 21 Dec
Holiday Inn Express Medellin by IHG

Hotel Central Plaza Medellin

Hotel Central Plaza Medellin
3.0 star property
5.4 km from San Diego
8.0 out of 10, Very good, (346)
"Excellent place to stay.. I’ll be back ."
United States
Isabel
The price is 1.839.423 ₫
2.180.057 ₫ total
20 Dec - 21 Dec
Hotel Central Plaza Medellin
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in San Diego

Find the best San Diego areas for the activities you enjoy most.

El Poblado

El Poblado is highly notable for its popular shops, and you might want to visit top sights like Golden Mile and Oviedo Shopping Center. See more of Medellín by jumping on the metro at Poblado Station or Aguacatala Station.

Laureles

Laureles is known for its ample dining options, and you can make a stop by Unicentro Shopping Center and Belén Andrés Escobar Sports Complex while in the area.

Provenza

If you're looking for some top things to see and do in Provenza and surrounding area, you can visit Golden Mile and Oviedo Shopping Center.

Laureles - Estadio

While you're in Laureles - Estadio, take in top sights like Atanasio Giradot Stadium or Unicentro Shopping Center, and hop on the metro to see more of the city at Estadio Station or Suramericana Station.

Zona Rosa

When in Zona Rosa, you can plan a visit to Golden Mile and Oviedo Shopping Center, some noteworthy sights in the nearby area.

Top San Diego Hotel Reviews

Frequently asked questions

What is San Diego like?
San Diego is a welcoming neighbourhood that travellers like for its restaurants and shopping. Consider a visit to San Diego Shopping Center as part of your San Diego travel plans.
How many hotels should I expect to find in San Diego?
Expedia has 92 hotels and other accommodation options in San Diego to choose from, making this an ideal home base for exploring the greater Medellín area.
If I need to cancel my hotel reservation in San Diego, will I receive a refund?
Yes! Most hotel reservations are fully refundable as long as you cancel prior to the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of your scheduled arrival. If you have a reservation that's non-refundable, you might be able to cancel it and get a refund within a 24-hour period of booking. Add dates, click "Search", then use the "fully refundable" filter to review top deals in San Diego.
What is there to do in this Medellín neighbourhood?
San Diego Shopping Center is an attraction you might want to check out while you're in San Diego. While you're out sightseeing, Premium Plaza Shopping Center and Medellin's Museum of Modern Art are a couple of additional sights to visit in Medellín.

Explore a world of travel with Expedia