San Sisto Holidays

Book a Hotel + Flight or Car together to unlock savings

Top hotels in San Sisto

Giotto Hotel & Spa

Giotto Hotel & Spa

4 out of 5
Via Fontebella 41, Assisi, PG
Fully refundableReserve now, pay when you stay
8.8/10 Excellent! (718 reviews)
"Beautiful and clean hotel. Perfect location. Beautiful restaurant views. 100% recommended"

Reviewed on 9 Aug 2025

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Giotto Hotel & Spa
Hotel Ilgo

Hotel Ilgo

3 out of 5
Via Di Duccio Agostino 1, Perugia, PG
Fully refundableReserve now, pay when you stay
7.8/10 Good! (246 reviews)
"Easy walk to the historic old town"

Reviewed on 21 Oct 2024

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Hotel Ilgo
Villa di Piazzano - Small Luxury Hotel of the World

Villa di Piazzano - Small Luxury Hotel of the World

5 out of 5
Localita Piazzano, C.P. 6, Cortona, AR
Fully refundableReserve now, pay when you stay
The price is 15.872.170 ₫ per night from 31 Aug to 1 Sept
15.872.170 ₫
17.705.351 ₫ total
31 Aug - 1 Sept
includes taxes & fees
9.6/10 Exceptional! (218 reviews)
"AMAZING! Gorgeous! I would recommend to everyone!"

Reviewed on 29 Jul 2025

Villa di Piazzano - Small Luxury Hotel of the World
See all 3,419 properties in San Sisto
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Popular places to visit

Perugia showing a city

Corso Vannucci

Learn about the local history of Perugia with a stop at Corso Vannucci. You can enjoy the bars while in the area.

Corso Vannucci
Rocca Paolina showing heritage architecture

Rocca Paolina

You can learn about the history of Perugia with a visit to Rocca Paolina. While you're in the area, find time to visit its stunning cathedral.

Rocca Paolina
Basilica San Pietro which includes religious elements, interior views and heritage architecture

Basilica San Pietro

Learn about the local history of Perugia when you spend time at Basilica San Pietro. While you're in the area, find time to visit its stunning cathedral.

Basilica San Pietro

Frequently asked questions

How much does a San Sisto holiday package cost?
You can snap up a holiday package to this destination on Expedia. However, how much your holiday to San Sisto costs will depend on factors like the season, hotel choice and length of stay.
What are the cheapest months to go to San Sisto?
You're likely to find lower prices and better availability in January, February and March. Browse our cheap San Sisto holiday packages and you could get some excellent off-season deals.
How many days is enough for San Sisto?
With a well-planned schedule, you can easily tick off the most popular San Sisto sights in a few days. But if you want to discover hidden gems or go on day trips, consider booking your San Sisto holiday for longer.
How to find the best San Sisto package deals?
Use Expedia's handy filters to help you find some great San Sisto package deals. When you start your search, simply set your maximum budget and then sort the results by "Price: low to high." If you want to save, plan your escape for midweek, or browse for San Sisto package deals in the off-season. Switch up your travel dates and you may score even better discounts. As a rule of thumb, it's typically best to book your holiday package as early as possible.
Is it cheaper to book a San Sisto holiday as a package?
Expedia holiday packages are designed to help you keep more money in your pocket. Bundle your hotel, flight and car rental into one great-value price and you could save hundreds of dollars. You'll usually get a better deal than booking each component separately. And you'll still get the flexibility to create a tailored San Sisto holiday by choosing your favourite type of stay, airline and car class.
When to book a holiday package to San Sisto?
If you're planning a spur-of-the-moment San Sisto getaway, browse our last-minute deals that can be booked up to one week before you take off. Prefer not to wait until the last minute? You can land incredible deals on your hotels and flights by booking well in advance.
How to plan a trip to San Sisto?

  1. Choose your travel dates: What you'd like to do in San Sisto and your favourite season can help you decide when to go.
  2. Set a budget: Factor in costs like flights, food and transportation when working out how much to save for your trip to San Sisto. Then, choose a property that suits your budget, whether that's an affordable option or a more luxurious retreat.
  3. Determine how many days away: Start by making a list of all the activities and attractions you want to get to in San Sisto. Then, estimate how long you'll need for each, along with any travel time.
  4. Bundle your bookings: With your travel dates in order, you can combine your car rental, hotels, flights and more into a customised San Sisto holiday package.