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17 Dec - 18 Dec
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18 Dec - 19 Dec
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19 Dec - 21 Dec
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26 Dec - 28 Dec

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Our top choices for Sant'Eustachio hotels

Terrace/patio
Hotel Smeraldo

Hotel Smeraldo

Hotel Smeraldo
3.0 star property
Sant'Eustachio
9.6 out of 10, Exceptional, (1003)
"We have stayed here before and they staff and facility are top notch. Definitely recommend this hotel.."
Canada
Terry
The price is 3.148.848 ₫
3.834.847 ₫ total
includes taxes & fees
11 Jan - 12 Jan 2026
Hotel Smeraldo
Courtyard
Hotel Navona

Hotel Navona

Hotel Navona
3.0 star property
Sant'Eustachio
9.0 out of 10, Wonderful, (1004)
"Great location and great breakfast"
United States
Christine
The price is 2.877.913 ₫
3.537.068 ₫ total
includes taxes & fees
11 Jan - 12 Jan 2026
Hotel Navona
Classic Double Room | View from room
Dulcis Inn Pantheon

Dulcis Inn Pantheon

Dulcis Inn Pantheon
Sant'Eustachio
8.6 out of 10, Excellent, (391)
"The room was cream and the staff really kind "
United Kingdom
Salvatore Francesco
The price is 2.606.976 ₫
3.177.144 ₫ total
includes taxes & fees
7 Jan - 8 Jan 2026
Dulcis Inn Pantheon
Junior Suite, 1 King Bed, City View | Premium bedding, down duvets, in-room safe, desk
Torre Argentina Relais

Torre Argentina Relais

Torre Argentina Relais
Sant'Eustachio
9.4 out of 10, Exceptional, (536)
"Everything was great. Views, safety, staff, breakfast, room, and accommodations. "
United States
Zachariah
Torre Argentina Relais
Free daily buffet breakfast
Hotel L'Orologio Roma

Hotel L'Orologio Roma

Hotel L'Orologio Roma
4.0 star property
Sant'Eustachio
9.6 out of 10, Exceptional, (426)
"Great spacious room, big clean bathroom and very helpful staff. Very beautifully decorated hotel.just I hoped to receive a Rolex by the end of my stay but instead I received a Prosecco 🍾 "
United States
NADINE
The price is 6.452.327 ₫
7.561.453 ₫ total
includes taxes & fees
6 Jan - 7 Jan 2026
Hotel L'Orologio Roma
Lobby
Hotel della Torre Argentina

Hotel della Torre Argentina

Hotel della Torre Argentina
3.0 star property
Sant'Eustachio
9.0 out of 10, Wonderful, (260)
"Great location hotel, rooms were well equipped. Staff were friendly and helpful. Breakfast was just right for starting the day"
United Kingdom
Gareth
Hotel della Torre Argentina
Premium bedding, free minibar, in-room safe, desk
Hotel Barrett

Hotel Barrett

Hotel Barrett
3.0 star property
Sant'Eustachio
9.0 out of 10, Wonderful, (445)
"lovely hotel with a keen eye for detail"
United Kingdom
JACKI
The price is 3.365.331 ₫
4.072.979 ₫ total
includes taxes & fees
18 Dec - 19 Dec
Hotel Barrett
Rooftop bar
The Pantheon Iconic Rome Hotel, Autograph Collection

The Pantheon Iconic Rome Hotel, Autograph Collection

The Pantheon Iconic Rome Hotel, Autograph Collection
5.0 star property
Sant'Eustachio
9.2 out of 10, Wonderful, (145)
"Fantastic place to stay."
Australia
Srdjan
The price is 11.628.246 ₫
13.409.595 ₫ total
includes taxes & fees
7 Jan - 8 Jan 2026
The Pantheon Iconic Rome Hotel, Autograph Collection
Exterior
Palazzo Navona

Palazzo Navona

Palazzo Navona
4.0 star property
Sant'Eustachio
9.4 out of 10, Exceptional, (1000)
"Amazing staff!!!"
Canada
Anna
The price is 26.009.486 ₫
29.074.328 ₫ total
includes taxes & fees
31 Dec - 1 Jan 2026
Palazzo Navona
Deluxe Double Room, 1 Double Bed, City View | Premium bedding, minibar, in-room safe, individually furnished
Little Queen Relais

Little Queen Relais

Little Queen Relais
Sant'Eustachio
8.8 out of 10, Excellent, (106)
"!"
Mexico
Alexandra
The price is 3.453.236 ₫
4.169.673 ₫ total
includes taxes & fees
14 Jan - 15 Jan 2026
Little Queen Relais
Deluxe Double or Twin Room Carolina | Egyptian cotton sheets, premium bedding, Select Comfort beds, minibar
Feronia Guest House

Feronia Guest House

Feronia Guest House
Sant'Eustachio
8.4 out of 10, Very good, (34)
"Clean and spacious room, great location walking distance to plenty of restaurants and relatively close to the Pantheon. "
Australia
Caitlin
Feronia Guest House
Superior Double or Twin Beds (Annex: Via del Sudario, 27) | View from room
Argentina Residenza Style Hotel

Argentina Residenza Style Hotel

Argentina Residenza Style Hotel
4.0 star property
Sant'Eustachio
9.4 out of 10, Exceptional, (1004)
"Very comfortable and well fitted room; very helpful staff and excellent location. "
United Kingdom
Karen
The price is 4.578.666 ₫
5.500.738 ₫ total
includes taxes & fees
11 Jan - 12 Jan 2026
Argentina Residenza Style Hotel
Deluxe Room | View from room
The Spanish Suite Campo de Fiori

The Spanish Suite Campo de Fiori

The Spanish Suite Campo de Fiori
Sant'Eustachio
8.4 out of 10, Very good, (208)
"Nice area good service on the lobby "
United States
Hector
The price is 7.033.327 ₫
8.046.223 ₫ total
includes taxes & fees
29 Dec - 30 Dec
The Spanish Suite Campo de Fiori
Deluxe Double Room, Jetted Tub | Premium bedding, pillow-top beds, minibar, in-room safe
Magenta Collection Sant'Anna

Magenta Collection Sant'Anna

Magenta Collection Sant'Anna
Sant'Eustachio
9.0 out of 10, Wonderful, (93)
"Property was convenient and walking distance from all the great sights and restaurants."
United States
Rashelle
Magenta Collection Sant'Anna
View from room
Relais Maddalena

Relais Maddalena

Relais Maddalena
Sant'Eustachio
9.4 out of 10, Exceptional, (794)
"The room was very nice and cozy The location is good The staff is nice "
United States
sandra
The price is 5.253.938 ₫
6.150.446 ₫ total
includes taxes & fees
22 Dec - 23 Dec
Relais Maddalena
Terrace/patio
Lh Royal Suites

Lh Royal Suites

Lh Royal Suites
Sant'Eustachio
9.4 out of 10, Exceptional, (70)
"The property was good. Rooms were clean."
United Kingdom
Alina
The price is 3.010.300 ₫
3.682.694 ₫ total
includes taxes & fees
7 Jan - 8 Jan 2026
Lh Royal Suites
Exterior detail
VELVET GREY BOUTIQUE HOTEL ROMA

VELVET GREY BOUTIQUE HOTEL ROMA

VELVET GREY BOUTIQUE HOTEL ROMA
Sant'Eustachio
9.2 out of 10, Wonderful, (48)
"Room was very clean, quiet, amazing location and friendly, calm staff. I had a lovely stay and highly recommend. "
United States
Sage
The price is 3.087.021 ₫
3.766.837 ₫ total
includes taxes & fees
24 Dec - 25 Dec
VELVET GREY BOUTIQUE HOTEL ROMA
Property entrance
Assunta Domus

Assunta Domus

Assunta Domus
Sant'Eustachio
9.6 out of 10, Exceptional, (221)
"Very pleasant stay in a safe and easily walkable neighbourhood."
Canada
Sandy
The price is 5.769.140 ₫
6.717.168 ₫ total
includes taxes & fees
28 Dec - 29 Dec
Assunta Domus
Property entrance
Hotel dei Barbieri

Hotel dei Barbieri

Hotel dei Barbieri
4.0 star property
Sant'Eustachio
8.6 out of 10, Excellent, (182)
"Excellent location, accommodating and helpful staff. "
United States
Stephen
The price is 4.357.781 ₫
5.257.452 ₫ total
includes taxes & fees
12 Jan - 13 Jan 2026
Hotel dei Barbieri
Front of property
Hotel Mimosa

Hotel Mimosa

Hotel Mimosa
1.0 star property
Sant'Eustachio
8.4 out of 10, Very good, (459)
"Centrally located-definitely would stay there again."
United States
Tweety
Hotel Mimosa
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in Sant'Eustachio

Find the best Sant'Eustachio areas for the activities you enjoy most.

Rome City Centre

Trevi Fountain and Piazza Navona are a few top attractions in Rome City Centre. Hop around the city on the metro at Venezia Tram Stop or Arenula-Cairoli Tram Station and check out the area's fascinating museums, stunning cathedral and stunning river views.

Rome Historic Centre which includes a fountain, a square or plaza and a statue or sculpture

Rome Historic Centre

Known for its fascinating museums, stunning cathedral and charming cafes, there's plenty to explore in Rome Historic Centre. Top attractions like Colosseum and Trevi Fountain are major draws. Catch the metro at Venezia Tram Stop or Colosseo Station to see more of the city.

Trastevere

Spend some time visiting places like Basilica of Santa Maria in Trastevere while getting to know Trastevere, and be sure to check out the colourful gardens. You can hop aboard the metro at Trastevere/Min. P. Istruzione Tram Stop or Induno Tram Stop to see more of the area.

Monti which includes heritage elements, building ruins and heritage architecture

Monti

Known for its prominent churches and charming cafes, there's plenty to explore in Monti. You can visit top attractions like San Pietro in Vincoli and Via del Boschetto, and jump on the metro at Cavour Station or Colosseo Station to see more of the city.

Trevi

Art galleries, churches and museums are just a few things travellers like about Trevi. Sights like Trevi Fountain and Piazza di Trevi are spots to explore, and you can get around the greater Rome area at Barberini Station.

Top Sant'Eustachio Hotel Reviews

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Frequently asked questions

What's it like in Sant'Eustachio?
Guests are sure to enjoy their time checking out all that Rome's Sant'Eustachio neighbourhood has to offer. Are you looking for Sant'Eustachio travel tips? Make sure that you visit Palazzo Madama and San Luigi dei Francesi while you're in the neighbourhood.
How many hotels will I be able to find in Sant'Eustachio?
Expedia has 174 hotels and other accommodation options in Sant'Eustachio to choose from, making this an ideal home base for exploring the greater Rome area.
If I need to cancel my hotel reservation in Sant'Eustachio, will I receive a refund?
Yes! The majority of room reservations are fully refundable provided that you cancel before the hotel's cancellation deadline, which is usually within 24-48 hours of your arrival date. If you booked a non-refundable reservation, it may still be possible to cancel it and be given a refund within 24 hours of booking. Put your dates in and click on "Search", then you can use the "fully refundable" filter to get the best options available in Sant'Eustachio.
What is there to do in this Rome neighbourhood?
Palazzo Madama, San Luigi dei Francesi and Teatro Argentina are notable landmarks to see while you're in Sant'Eustachio. You could also plan a visit to Corso Vittorio Emanuele II or Sant'Ivo alla Sapienza while you're in the neighbourhood. Favourite places to visit in the surrounding area include Piazza Navona, Trevi Fountain and Spanish Steps. While you're out sightseeing, Colosseum and Campo de' Fiori are a couple of additional sights to visit in Rome.