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Check availability on Santa Ana Business Hotels

Our top choices for Santa Ana business-friendly hotels

Property amenity
MainStay Suites John Wayne Airport by Choice Hotels

MainStay Suites John Wayne Airport by Choice Hotels

MainStay Suites John Wayne Airport by Choice Hotels
2.5 star property
Santa Ana
8.0 out of 10, Very good, (1487)
"Friendly Staff, Spacious and Clean rooms"
United States
HIENSI
The price is 2.462.335 ₫
2.787.240 ₫ total
includes taxes & fees
21 Dec - 22 Dec
MainStay Suites John Wayne Airport by Choice Hotels
Exterior
Holiday Inn Santa Ana Orange County Airport by IHG

Holiday Inn Santa Ana Orange County Airport by IHG

Holiday Inn Santa Ana Orange County Airport by IHG
3.0 star property
Santa Ana
8.8 out of 10, Excellent, (1123)
"Staff was friendly, room was clean, breakfast was fantastic."
United States
Carmen
The price is 2.392.622 ₫
2.708.329 ₫ total
includes taxes & fees
22 Dec - 23 Dec
Holiday Inn Santa Ana Orange County Airport by IHG
Exterior
Best Western Plus Orange County Airport North

Best Western Plus Orange County Airport North

Best Western Plus Orange County Airport North
2.5 star property
Santa Ana
8.6 out of 10, Excellent, (1704)
"It was a great stay"
United States
magali
The price is 2.724.788 ₫
3.079.010 ₫ total
includes taxes & fees
21 Dec - 22 Dec
Best Western Plus Orange County Airport North
Dining
La Quinta Inn & Suites by Wyndham Orange County Airport

La Quinta Inn & Suites by Wyndham Orange County Airport

La Quinta Inn & Suites by Wyndham Orange County Airport
3.0 star property
Santa Ana
7.8 out of 10, Good, (2013)
"My family and I enjoyed our stay. Would book again."
United States
Latausha
The price is 2.341.415 ₫
2.645.799 ₫ total
includes taxes & fees
16 Dec - 17 Dec
La Quinta Inn & Suites by Wyndham Orange County Airport
Exterior
Hotel Zessa Orange County Airport, a DoubleTree by Hilton

Hotel Zessa Orange County Airport, a DoubleTree by Hilton

Hotel Zessa Orange County Airport, a DoubleTree by Hilton
4.0 star property
Santa Ana
9.0 out of 10, Wonderful, (560)
"We had a beautiful stay. "
United States
Lawrence
The price is 2.782.754 ₫
3.144.511 ₫ total
includes taxes & fees
21 Dec - 22 Dec
Hotel Zessa Orange County Airport, a DoubleTree by Hilton
Exterior
Comfort Inn & Suites Orange County John Wayne Airport

Comfort Inn & Suites Orange County John Wayne Airport

Comfort Inn & Suites Orange County John Wayne Airport
2.5 star property
Santa Ana
8.0 out of 10, Very good, (1005)
"Room seemed newly renovated, great access, it was quiet and I would definitely would think about this hotel if staying around the area again"
United States
Salvador
The price is 2.397.094 ₫
2.713.391 ₫ total
includes taxes & fees
22 Dec - 23 Dec
Comfort Inn & Suites Orange County John Wayne Airport
Coffee service
Sonesta Simply Suites Orange County Airport

Sonesta Simply Suites Orange County Airport

Sonesta Simply Suites Orange County Airport
2.0 star property
Santa Ana
7.4 out of 10, Good, (1001)
"Conviently located next to John Wayne airport and quiet."
United States
Phong
The price is 2.446.551 ₫
2.769.374 ₫ total
includes taxes & fees
4 Jan - 5 Jan 2026
Sonesta Simply Suites Orange County Airport
Outdoor pool
Holiday Inn Express & Suites Santa Ana - Orange County by IHG

Holiday Inn Express & Suites Santa Ana - Orange County by IHG

Holiday Inn Express & Suites Santa Ana - Orange County by IHG
2.5 star property
Lyon Street
8.6 out of 10, Excellent, (1218)
"enjoyed our stay."
United States
Melissa
The price is 2.998.998 ₫
3.394.716 ₫ total
includes taxes & fees
21 Dec - 22 Dec
Holiday Inn Express & Suites Santa Ana - Orange County by IHG
Outdoor pool, open 6:00 AM to 10:00 PM, pool loungers
Courtyard by Marriott Santa Ana Orange County

Courtyard by Marriott Santa Ana Orange County

Courtyard by Marriott Santa Ana Orange County
3.0 star property
Santa Ana
8.6 out of 10, Excellent, (1000)
"The staff and hotel were fantastic and it was very quiet during my stay"
United States
JAMES
The price is 3.054.243 ₫
3.457.250 ₫ total
includes taxes & fees
18 Dec - 19 Dec
Courtyard by Marriott Santa Ana Orange County
Exterior
Orange County Hotel

Orange County Hotel

Orange County Hotel
3.5 star property
Santa Ana
7.2 out of 10, Good, (1001)
"Nice place, good rate, nice staff."
United States
Chad
The price is 2.946.384 ₫
3.335.160 ₫ total
includes taxes & fees
28 Dec - 29 Dec
Orange County Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top Santa Ana Hotel Reviews

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Frequently asked questions

How much do business-friendly hotels in Santa Ana cost?
Prices for business hotels in Santa Ana range between 2.645.799 ₫ and 3.457.250 ₫ per night. Whatever your budget, Expedia will help you locate the best place to get the job done. These prices were available on Expedia within the past 7 days, for a hotel booking with a check-in date within the next year. Prices reflect current offers and availability is subject to change. Additional terms may apply.
What are the best business-friendly hotels in Santa Ana?
Select from multiple business-friendly hotels in Santa Ana that have a total average guest review rating of 8.1. Courtyard by Marriott Anaheim Theme Park Entrance is a favourite among corporate travellers. This 3.5-stars property features amenities such as a waterslide and a swimming pool. Ayres Hotel Orange is another highly rated option. It has a 3.5-stars rating and conveniences including a swimming pool and an electric car charging station.
How many business-friendly hotels are there in Santa Ana?
Santa Ana offers 17 hotels that accommodate corporate travellers. Whether you're looking for a location closer to the city or amenities like conference rooms and dependable WiFi, you'll find a well-suited property on Expedia.
What are the best cheap business-friendly hotels in Santa Ana?
Business-friendly hotels in Santa Ana start at 2.645.799 ₫ per night, so your work-related trip doesn't have to cost a lot. Best Western Plus Anaheim Inn is a reasonably priced choice that comes with plenty of amenities, like a terrace and a swimming pool. Holiday Inn Express & Suites Anaheim Resort Area, an IHG Hotel is another cheap stay that's favoured by corporate guests. Conveniences here include a memory foam mattress and an electric car charging station. When you're ready to see the sights of Santa Ana, add a few free attractions to your work trip agenda. Old Orange County Courthouse and Jack & Shanaz Langson Institute & Museum of California Art are favourites. This price was available on Expedia within the past 7 days, for a hotel booking with a check-in date within the next year. Prices reflect current offers and availability is subject to change. Additional terms may apply.
What are the top business-friendly motels in Santa Ana?
Motel 6 Anaheim Hills is a popular choice, located around 14 km northeast of downtown Santa Ana. Featuring a steam room and a swimming pool, this business-friendly motel has the amenities you need to work and play. Motel 6 Irvine - Orange County Airport also caters to corporate travellers. It's approximately 5 km south of central Santa Ana and includes a swimming pool, a spa tub and more.With lots of shopping, cultural and dining options to discover, you might consider extending your corporate trip to Santa Ana. Disneyland® Resort and Disney California Adventure® Park are terrific places to kick off your sightseeing adventures.
Are there any family-friendly hotels in Santa Ana that are also business friendly?
Courtyard by Marriott Anaheim Theme Park Entrance is popular with both leisure and corporate guests. A waterslide and a nearby theme park are just two of the amenities offered at this 3.5-stars Santa Ana stay. Alternatively, holiday with the fam and work on the road at Ayres Hotel Orange. You'll have use of conveniences like complimentary breakfast and a nearby theme park at this leading 3.5-stars option. Once work is out of the way, there are lots of family-friendly attractions to see around Santa Ana. Disneyland® Resort and Disney California Adventure® Park are two of our top picks.
Are there any 5-star business-friendly hotels in Santa Ana?
Santa Ana doesn't have any 5-star business-friendly hotels — but there are still some upmarket accommodation where you can base yourself for work. Why not book Avenue of the Arts Costa Mesa, a Tribute Portfolio Hotel? Around 6 km from downtown, this 4-star favourite comes with nice extras like a spa tub and a sauna. DoubleTree Suites by Hilton Anaheim Rsrt - Conv Cntr is another fantastic choice for busy business types, and is located just 6 km from central Santa Ana. Also with a 4-star rating, it features amenities such as proposal/romance packages and a spa tub.
Why book your business-friendly hotel in Santa Ana with Expedia?
Expedia will help you find an ideal business-friendly hotel for your upcoming work trip. From free WiFi and parking to on-site restaurants and more, our stays have all the amenities you'll need to close that big deal.
How can I find cheap business-friendly hotels in Santa Ana?
When work takes you to Santa Ana, our "business friendly" filter will help you find a suitable hotel. From free WiFi and included breakfast to concierge services and conference spaces, they come with the amenities you need for a comfortable and productive stay. You can also refine your search by your preferred star rating and budget to see the most affordable properties.
What is there to do in Santa Ana near my business-friendly hotel?
Santa Ana has enough experiences and activities to keep you going for weeks, beginning with Disneyland® Resort. Disney California Adventure® Park, Segerstrom Centre for the Arts and Santa Ana Zoo are other awesome attractions. If your business trip gives you time to spare, Adventure City and Great Wolf Lodge Water Park will add the finishing touches to your itinerary.