Santa Fe Lake

A waterfront with Spanish moss-covered trees, a wooden dock, and a distant shoreline.

Top Hotel Deals

Best Western Waldo Inn and Suites

Best Western Waldo Inn and Suites

2.5 out of 5
17230 Ne Us Highway 301 Waldo FL
Best Western Waldo Inn and Suites
Holiday Inn Express Starke by IHG

Holiday Inn Express Starke by IHG

2.5 out of 5
15111 S.Highway 301 Starke FL
Holiday Inn Express Starke by IHG
Hotel Eleo at the University of Florida

Hotel Eleo at the University of Florida

3 out of 5
1514 Southwest 14th Street Gainesville FL
Hotel Eleo at the University of Florida
Comfort Suites Gainesville near University

Comfort Suites Gainesville near University

2.5 out of 5
2603 SW 13TH STREET Gainesville FL
Comfort Suites Gainesville near University
Drury Inn & Suites Gainesville

Drury Inn & Suites Gainesville

3 out of 5
4000 Southwest 40th Blvd Gainesville FL
Drury Inn & Suites Gainesville
Days Inn by Wyndham Gainesville Hospital/University Area

Days Inn by Wyndham Gainesville Hospital/University Area

2.5 out of 5
2649 Sw 13th St Gainesville FL
Days Inn by Wyndham Gainesville Hospital/University Area
Gainesville Lodge

Gainesville Lodge

2 out of 5
413 West University Ave Gainesville FL
Gainesville Lodge
Best Western Starke

Best Western Starke

2.5 out of 5
1290 N Temple Ave Starke FL
Best Western Starke
Motel 6 Starke, FL

Motel 6 Starke, FL

2 out of 5
1101 N. Temple Ave. Starke FL
Motel 6 Starke, FL
See all 1,406 properties in Santa Fe Lake
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.