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Tonight
19 Dec - 20 Dec
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20 Dec - 21 Dec
This weekend
19 Dec - 21 Dec
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26 Dec - 28 Dec

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Our top choices for Santa Fe hotels

Triple Room | Hypo-allergenic bedding, free WiFi, bed sheets
Ayenda Casa San Pablo

Ayenda Casa San Pablo

Ayenda Casa San Pablo
2.5 star property
Santa Fe
8.0 out of 10, Very good, (7)
"Room was very small, the bathroom tiny and uncomfortable to navigate. Facilities were clean and the staff courteous."
United States
Jose
The price is 1.609.827 ₫
1.609.827 ₫ total
2 Jan - 3 Jan 2026
Ayenda Casa San Pablo
Reception
Hotel Boutique Olaya 54

Hotel Boutique Olaya 54

Hotel Boutique Olaya 54
3.0 star property
Santa Fe
10.0 out of 10, Exceptional, (1)
"Convenient and cozy . Per friendly was a plus ! "
United States
Alfonso
The price is 1.609.183 ₫
1.609.183 ₫ total
20 Dec - 21 Dec
Hotel Boutique Olaya 54
Outdoor pool
Hotel San Fernando Plaza

Hotel San Fernando Plaza

Hotel San Fernando Plaza
4.0 star property
La Florida, 2.3 km from Santa Fe
9.2 out of 10, Wonderful, (1002)
"Amazing people and breakfast "
United States
Miguel
The price is 2.242.440 ₫
2.242.440 ₫ total
21 Dec - 22 Dec
Hotel San Fernando Plaza
4 restaurants, breakfast served
Dann Carlton Medellin Hotel

Dann Carlton Medellin Hotel

Dann Carlton Medellin Hotel
4.5 star property
Provenza, 2 km from Santa Fe
8.8 out of 10, Excellent, (1672)
"Excelente hotel 5 estrellas. "
United States
Emmanuel
The price is 2.354.971 ₫
2.354.971 ₫ total
12 Jan - 13 Jan 2026
Dann Carlton Medellin Hotel
Breakfast, lunch, dinner served; American cuisine
Hotel Park 10

Hotel Park 10

Hotel Park 10
4.0 star property
Lalinde, 2.2 km from Santa Fe
9.2 out of 10, Wonderful, (1219)
"Room was clean, breakfast was excellent "
Canada
Martha
The price is 3.435.795 ₫
3.435.795 ₫ total
9 Jan - 10 Jan 2026
Hotel Park 10
Exterior
TEVA Glamping & Retreat

TEVA Glamping & Retreat

TEVA Glamping & Retreat
3.5 star property
15 km from Santa Fe
9.2 out of 10, Wonderful, (110)
"Friendly staff, clean , good food . "
United States
Katherine
TEVA Glamping & Retreat
Breakfast, lunch, dinner served; Italian cuisine
Hotel Santiago de Arma

Hotel Santiago de Arma

Hotel Santiago de Arma
3.0 star property
16.7 km from Santa Fe
9.2 out of 10, Wonderful, (910)
"Very clean room and very friendly staff."
United States
Redding
Hotel Santiago de Arma
Daily buffet breakfast (COP 45000 per person)
Hashtag 98 Hotel By Jalo

Hashtag 98 Hotel By Jalo

Hashtag 98 Hotel By Jalo
4.0 star property
Zona Rosa, 1.9 km from Santa Fe
9.2 out of 10, Wonderful, (1626)
"Excellent costumer service clean rooms great location "
United States
sandra
The price is 1.809.620 ₫
1.809.620 ₫ total
23 Dec - 24 Dec
Hashtag 98 Hotel By Jalo
Couples treatment room(s), sauna, hot tub, Turkish bath/hammam
Movich Hotel Las Lomas

Movich Hotel Las Lomas

Movich Hotel Las Lomas
4.0 star property
17.1 km from Santa Fe
9.0 out of 10, Wonderful, (1002)
"Its a food hotel , perfectly "
United States
Roberto
The price is 4.226.557 ₫
4.226.557 ₫ total
26 Dec - 27 Dec
Movich Hotel Las Lomas
Club Cabin, Accessible | Premium bedding, individually furnished, blackout curtains, free WiFi
Isak Hotel & Golf Airport

Isak Hotel & Golf Airport

Isak Hotel & Golf Airport
3.0 star property
16.3 km from Santa Fe
9.4 out of 10, Exceptional, (546)
"Great staff, good breakfast, very clean and conveniently located close to airport!"
Canada
Philippe
The price is 1.778.109 ₫
1.778.109 ₫ total
4 Jan - 5 Jan 2026
Isak Hotel & Golf Airport
Restaurant
Calle Flora Hotel by Jalo

Calle Flora Hotel by Jalo

Calle Flora Hotel by Jalo
3.5 star property
Zona Rosa, 2.2 km from Santa Fe
9.2 out of 10, Wonderful, (308)
"Good place to stay"
United States
Obed
The price is 1.867.014 ₫
1.867.014 ₫ total
23 Dec - 24 Dec
Calle Flora Hotel by Jalo
2 restaurants, breakfast, lunch, dinner served; Italian cuisine
V Grand Hotel, a member of Radisson Individuals

V Grand Hotel, a member of Radisson Individuals

V Grand Hotel, a member of Radisson Individuals
3.5 star property
1.6 km from Santa Fe
9.2 out of 10, Wonderful, (1275)
"Excellent and a highly recommended place to stay. Great hospitality from staff."
United States
Miguel Angel Guzman
The price is 2.316.512 ₫
2.316.512 ₫ total
20 Dec - 21 Dec
V Grand Hotel, a member of Radisson Individuals
Superior Double Room, 1 Queen Bed | Minibar, in-room safe, desk, blackout curtains
Hotel Lagoon

Hotel Lagoon

Hotel Lagoon
3.5 star property
19 km from Santa Fe
9.2 out of 10, Wonderful, (297)
"Nice property, very good food, very relaxing."
United States
Kevin
The price is 3.176.832 ₫
3.176.832 ₫ total
25 Dec - 26 Dec
Hotel Lagoon
2 restaurants, breakfast, lunch, dinner served; local cuisine
Novotel Medellín El Tesoro

Novotel Medellín El Tesoro

Novotel Medellín El Tesoro
4.5 star property
3.8 km from Santa Fe
9.2 out of 10, Wonderful, (1359)
"Great staff great breakfast very clean wonderful attitudes from everyone"
United States
Jon
The price is 3.476.123 ₫
3.476.123 ₫ total
27 Dec - 28 Dec
Novotel Medellín El Tesoro
Front of property
Lettera Hotel

Lettera Hotel

Lettera Hotel
3.5 star property
La Florida, 3 km from Santa Fe
9.8 out of 10, Exceptional, (448)
"Everything was wonderful from the rooms, kindness from the staff, and food!"
United States
Katai Jurani Hidalgo
Lettera Hotel
Grand Studio Suite, 1 King Bed, Hot Tub, Ground Floor | Hypo-allergenic bedding, down duvets, minibar, in-room safe
The Somos Bold Hotel

The Somos Bold Hotel

The Somos Bold Hotel
4.0 star property
Manila, 1.4 km from Santa Fe
9.2 out of 10, Wonderful, (227)
"WAS PERFECT!"
Canada
Irina
The price is 2.242.222 ₫
2.242.222 ₫ total
23 Dec - 24 Dec
The Somos Bold Hotel
Luxury Suite | Private spa tub
Hotel Attic 33

Hotel Attic 33

Hotel Attic 33
3.0 star property
Laureles, 1.9 km from Santa Fe
9.6 out of 10, Exceptional, (11)
"Was great, very recommended for a quick trip. "
United States
jorge
The price is 1.262.650 ₫
1.262.650 ₫ total
11 Jan - 12 Jan 2026
Hotel Attic 33
Outdoor pool, pool umbrellas
Hotel Dann Carlton Belfort Medellin

Hotel Dann Carlton Belfort Medellin

Hotel Dann Carlton Belfort Medellin
4.0 star property
1.5 km from Santa Fe
8.8 out of 10, Excellent, (1000)
"Beatiful hotel with impeccable service !"
United States
Miodrag
The price is 2.085.060 ₫
2.085.060 ₫ total
21 Dec - 22 Dec
Hotel Dann Carlton Belfort Medellin
Outdoor pool, pool umbrellas, pool loungers
NH Collection Medellín Royal

NH Collection Medellín Royal

NH Collection Medellín Royal
5.0 star property
El Poblado, 2.9 km from Santa Fe
9.2 out of 10, Wonderful, (1001)
"Room was perfect, very modern settings and super comfortable beds."
United States
oscar
The price is 2.375.840 ₫
2.375.840 ₫ total
16 Jan - 17 Jan 2026
NH Collection Medellín Royal
Bar (on property)
Novelty Suites Hotel - Oviedo Mall

Novelty Suites Hotel - Oviedo Mall

Novelty Suites Hotel - Oviedo Mall
3.5 star property
La Aguacatala, 2.5 km from Santa Fe
9.4 out of 10, Exceptional, (932)
"Love this hotel excellent location, staff and breakfast "
United States
Patricia
The price is 2.919.341 ₫
2.919.341 ₫ total
23 Dec - 24 Dec
Novelty Suites Hotel - Oviedo Mall
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Where to stay in Santa Fe

Find the best Santa Fe areas for the activities you enjoy most.
El Castillo Museum showing heritage architecture and château or palace

El Poblado

El Poblado is highly notable for its popular shops, and you might want to visit top sights like Golden Mile and Oviedo Shopping Center. See more of Medellín by jumping on the metro at Poblado Station or Aguacatala Station.

Rock of Guatape featuring a house, mist or fog and tranquil scenes

Laureles

Laureles is known for its ample dining options, and you can make a stop by Unicentro Shopping Center and Belén Andrés Escobar Sports Complex while in the area.

Provenza

If you're looking for some top things to see and do in Provenza and surrounding area, you can visit Golden Mile and Oviedo Shopping Center.

Laureles - Estadio

While you're in Laureles - Estadio, take in top sights like Atanasio Giradot Stadium or Unicentro Shopping Center, and hop on the metro to see more of the city at Estadio Station or Suramericana Station.

Zona Rosa

When in Zona Rosa, you can plan a visit to Golden Mile and Oviedo Shopping Center, some noteworthy sights in the nearby area.

Top Santa Fe Hotel Reviews

Hunters By Jalo

Hunters By Jalo

10/10 Excellent
"Good hotel. Convenient location. "
Jaime 2-night trip
Posted 3 days ago
Hunters By Jalo

Frequently asked questions

What's it like in Santa Fe?
You'll be sure to have fun exploring Medellín's Santa Fe neighbourhood. Consider a visit to Santa Fe Zoological Park as part of your Santa Fe travel plans.
How many hotels will I be able to find in Santa Fe?
If you're searching for places to stay in Medellín, choose from one of Expedia's 12 hotels and other accommodation options in Santa Fe.
If I need to cancel my hotel reservation in Santa Fe, will I receive a refund?
Yes, you'll find most room reservations are refundable if you cancel prior to the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of the scheduled arrival. If you booked a non-refundable reservation, you might be able to cancel it and receive a refund within 24 hours of your booking. Add your dates and click on "Search", then use the "fully refundable" filter to review the top deals on offer in Santa Fe.
What is there to do around this Medellín neighbourhood?
Santa Fe Zoological Park is an attraction you might want to check out while you're in Santa Fe. While you're out sightseeing, Medellin's Museum of Modern Art and Monterrey Comercial Mall are a couple of additional sights to visit in Medellín.

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