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Check prices for these dates

Tonight
15 Dec - 16 Dec
Tomorrow
16 Dec - 17 Dec
This weekend
19 Dec - 21 Dec
Next weekend
26 Dec - 28 Dec

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Our top choices for Santa Fe hotels

Breakfast area
Ayenda Casa San Pablo

Ayenda Casa San Pablo

Ayenda Casa San Pablo
2.5 star property
Santa Fe
8.0 out of 10, Very good, (7)
"Room was very small, the bathroom tiny and uncomfortable to navigate. Facilities were clean and the staff courteous."
United States
Jose
The price is 1.634.252 ₫
1.634.252 ₫ total
27 Dec - 28 Dec
Ayenda Casa San Pablo
Front of property
Hotel Boutique Olaya 54

Hotel Boutique Olaya 54

Hotel Boutique Olaya 54
3.0 star property
Santa Fe
10.0 out of 10, Exceptional, (1)
"Convenient and cozy . Per friendly was a plus ! "
United States
Alfonso
The price is 1.575.255 ₫
1.575.255 ₫ total
16 Dec - 17 Dec
Hotel Boutique Olaya 54
Restaurant
Hashtag 98 Hotel By Jalo

Hashtag 98 Hotel By Jalo

Hashtag 98 Hotel By Jalo
4.0 star property
Zona Rosa, 1.9 km from Santa Fe
9.2 out of 10, Wonderful, (1620)
"Excellent costumer service clean rooms great location "
United States
sandra
The price is 1.837.098 ₫
1.837.098 ₫ total
18 Dec - 19 Dec
Hashtag 98 Hotel By Jalo
4 restaurants, breakfast served
Dann Carlton Medellin Hotel

Dann Carlton Medellin Hotel

Dann Carlton Medellin Hotel
4.5 star property
Provenza, 2 km from Santa Fe
8.8 out of 10, Excellent, (1667)
"Excelente hotel 5 estrellas. "
United States
Emmanuel
The price is 2.390.703 ₫
2.390.703 ₫ total
21 Dec - 22 Dec
Dann Carlton Medellin Hotel
Breakfast, lunch, dinner served; American cuisine
Hotel Park 10

Hotel Park 10

Hotel Park 10
4.0 star property
Lalinde, 2.2 km from Santa Fe
9.2 out of 10, Wonderful, (1222)
"Room was clean, breakfast was excellent "
Canada
Martha
The price is 3.487.926 ₫
3.487.926 ₫ total
9 Jan - 10 Jan 2026
Hotel Park 10
Couples treatment room(s), hot stone massages, Thai massages
Isak Hotel & Golf Airport

Isak Hotel & Golf Airport

Isak Hotel & Golf Airport
3.0 star property
16.3 km from Santa Fe
9.4 out of 10, Exceptional, (545)
"Great staff, good breakfast, very clean and conveniently located close to airport!"
Canada
Philippe
The price is 1.805.949 ₫
1.805.949 ₫ total
16 Dec - 17 Dec
Isak Hotel & Golf Airport
Reception
Hotel Santiago de Arma

Hotel Santiago de Arma

Hotel Santiago de Arma
3.0 star property
16.7 km from Santa Fe
9.2 out of 10, Wonderful, (906)
"Clean, nice room, good price "
United Kingdom
Aswin
Hotel Santiago de Arma
32-inch LED TV with satellite channels, TV
Hotel San Fernando Plaza

Hotel San Fernando Plaza

Hotel San Fernando Plaza
4.0 star property
La Florida, 2.3 km from Santa Fe
9.2 out of 10, Wonderful, (1008)
"Great location, clean and modern details, friendly staff."
United States
Alex
The price is 2.753.897 ₫
2.753.897 ₫ total
19 Dec - 20 Dec
Hotel San Fernando Plaza
Couples treatment room(s), sauna, hot tub, Turkish bath/hammam
Movich Hotel Las Lomas

Movich Hotel Las Lomas

Movich Hotel Las Lomas
4.0 star property
17.1 km from Santa Fe
9.0 out of 10, Wonderful, (1002)
"Its a food hotel , perfectly "
United States
Roberto
The price is 4.290.685 ₫
4.290.685 ₫ total
26 Dec - 27 Dec
Movich Hotel Las Lomas
Terrace/patio
Manila Hotel Boutique

Manila Hotel Boutique

Manila Hotel Boutique
3.5 star property
Manila, 1.5 km from Santa Fe
9.0 out of 10, Wonderful, (248)
"Great stay"
United States
John
Manila Hotel Boutique
Grand Studio | Living area | 55-inch Smart TV with cable channels
Calle Flora Hotel by Jalo

Calle Flora Hotel by Jalo

Calle Flora Hotel by Jalo
3.5 star property
Zona Rosa, 2.2 km from Santa Fe
9.2 out of 10, Wonderful, (305)
"Good place to stay"
United States
Obed
The price is 1.625.354 ₫
1.625.354 ₫ total
18 Dec - 19 Dec
Calle Flora Hotel by Jalo
Outdoor pool, open 9:00 AM to 8:00 PM, pool umbrellas, pool loungers
Heiss Hotel By Jalo

Heiss Hotel By Jalo

Heiss Hotel By Jalo
4.0 star property
El Poblado, 1.3 km from Santa Fe
9.2 out of 10, Wonderful, (1043)
"Great Place to stay"
United States
Douglas
The price is 1.837.085 ₫
1.837.085 ₫ total
16 Dec - 17 Dec
Heiss Hotel By Jalo
Front of property
HOTEL SELIS

HOTEL SELIS

HOTEL SELIS
3.5 star property
Zona Rosa, 2 km from Santa Fe
9.6 out of 10, Exceptional, (289)
"Clean room nice staff"
United States
Arlene
The price is 2.112.960 ₫
2.112.960 ₫ total
16 Dec - 17 Dec
HOTEL SELIS
Outdoor pool
The Charlee Hotel

The Charlee Hotel

The Charlee Hotel
5.0 star property
Zona Rosa, 2.2 km from Santa Fe
8.8 out of 10, Excellent, (1003)
"Amazing stay! "
United States
Jasmin
The price is 5.850.464 ₫
5.850.464 ₫ total
18 Dec - 19 Dec
The Charlee Hotel
Superior Double Room, 1 Queen Bed | Minibar, in-room safe, desk, blackout curtains
Hotel Lagoon

Hotel Lagoon

Hotel Lagoon
3.5 star property
19 km from Santa Fe
9.2 out of 10, Wonderful, (297)
"Nice property, very good food, very relaxing."
United States
Kevin
The price is 3.226.625 ₫
3.226.625 ₫ total
21 Dec - 22 Dec
Hotel Lagoon
Outdoor pool, free pool cabanas
Marquee Hotel

Marquee Hotel

Marquee Hotel
3.0 star property
Zona Rosa, 2.1 km from Santa Fe
9.2 out of 10, Wonderful, (120)
"The food was spectacular "
United States
Clint
The price is 3.464.451 ₫
3.464.451 ₫ total
16 Dec - 17 Dec
Marquee Hotel
Dining
Travelers Rio Verde Living Suites

Travelers Rio Verde Living Suites

Travelers Rio Verde Living Suites
3.5 star property
15.4 km from Santa Fe
8.4 out of 10, Very good, (464)
"Good property. "
United States
Ruth Marcela
Travelers Rio Verde Living Suites
Interior
Novotel Medellín El Tesoro

Novotel Medellín El Tesoro

Novotel Medellín El Tesoro
4.5 star property
3.8 km from Santa Fe
9.2 out of 10, Wonderful, (1357)
"Great staff great breakfast very clean wonderful attitudes from everyone"
United States
Jon
The price is 3.528.865 ₫
3.528.865 ₫ total
20 Dec - 21 Dec
Novotel Medellín El Tesoro
Sun deck
Blues Suites Medellin

Blues Suites Medellin

Blues Suites Medellin
4.0 star property
3.4 km from Santa Fe
9.0 out of 10, Wonderful, (1026)
"Very clean hotel, the staff is excelent and the restaurant on the top 10/10"
United States
Jacnel
The price is 2.842.964 ₫
2.842.964 ₫ total
23 Dec - 24 Dec
Blues Suites Medellin
Jetted bathtub
La Martina Boutique Hotel

La Martina Boutique Hotel

La Martina Boutique Hotel
3.5 star property
Manila, 1.4 km from Santa Fe
8.4 out of 10, Very good, (282)
"Very nice hotel, will be staying here again when I come back to Medellín "
United States
Ryan
La Martina Boutique Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in Santa Fe

Find the best Santa Fe areas for the activities you enjoy most.
El Castillo Museum showing heritage architecture and château or palace

El Poblado

El Poblado is highly notable for its popular shops, and you might want to visit top sights like Golden Mile and Oviedo Shopping Center. See more of Medellín by jumping on the metro at Poblado Station or Aguacatala Station.

Rock of Guatape featuring a house, mist or fog and tranquil scenes

Laureles

Laureles is known for its ample dining options, and you can make a stop by Unicentro Shopping Center and Belén Andrés Escobar Sports Complex while in the area.

Laureles - Estadio

While you're in Laureles - Estadio, take in top sights like Atanasio Giradot Stadium or Unicentro Shopping Center, and hop on the metro to see more of the city at Estadio Station or Suramericana Station.

Provenza

If you're looking for some top things to see and do in Provenza and surrounding area, you can visit Golden Mile and Oviedo Shopping Center.

Zona Rosa

When in Zona Rosa, you can plan a visit to Golden Mile and Oviedo Shopping Center, some noteworthy sights in the nearby area.

Top Santa Fe Hotel Reviews

Landmark Hotel

Landmark Hotel

10/10 Excellent
"Great experience overall"
Montgomery 3-night trip
Posted 1 day ago
Landmark Hotel

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Frequently asked questions

What's it like in Santa Fe?
You'll be sure to have fun exploring Medellín's Santa Fe neighbourhood. Consider a visit to Santa Fe Zoological Park as part of your Santa Fe travel plans.
How many hotels will I be able to find in Santa Fe?
If you're searching for places to stay in Medellín, choose from one of Expedia's 12 hotels and other accommodation options in Santa Fe.
If I need to cancel my hotel reservation in Santa Fe, will I receive a refund?
Yes, you'll find most room reservations are refundable if you cancel prior to the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of the scheduled arrival. If you booked a non-refundable reservation, you might be able to cancel it and receive a refund within 24 hours of your booking. Add your dates and click on "Search", then use the "fully refundable" filter to review the top deals on offer in Santa Fe.
What is there to do around this Medellín neighbourhood?
Santa Fe Zoological Park is an attraction you might want to check out while you're in Santa Fe. While you're out sightseeing, Medellin's Museum of Modern Art and Monterrey Comercial Mall are a couple of additional sights to visit in Medellín.