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Our top choices for Santa Maria di Castello hotels

So & Leo Guest House

So & Leo Guest House
Genoa Historical Centre, 0.4 km from Santa Maria di Castello
9.6 out of 10, Exceptional, (94)
"Great location at porto antico"
Switzerland
Adrian
The price is 2.773.244 ₫
3.235.451 ₫ total
includes taxes & fees
23 Dec - 24 Dec
So & Leo Guest House

Hotel Palazzo Grillo

Hotel Palazzo Grillo
4.0 star property
Genoa Historical Centre, 0.4 km from Santa Maria di Castello
9.4 out of 10, Exceptional, (387)
"Great quiet location."
Canada
Timothy
The price is 2.801.256 ₫
3.327.893 ₫ total
includes taxes & fees
6 Jan - 7 Jan 2026
Hotel Palazzo Grillo

Bristol Palace Hotel

Bristol Palace Hotel
5.0 star property
San Vincenzo, 0.6 km from Santa Maria di Castello
9.4 out of 10, Exceptional, (1002)
"Super clean, great breakfast and great service!!!"
United States
Edward
The price is 5.714.422 ₫
6.594.156 ₫ total
includes taxes & fees
23 Dec - 24 Dec
Bristol Palace Hotel

Palazzo Durazzo Suites

Palazzo Durazzo Suites
5.0 star property
Prè, 0.8 km from Santa Maria di Castello
9.6 out of 10, Exceptional, (26)
"Very comfortable room. Wonderful staff, very helpful! Beautiful hotel!"
United States
Valerie
Palazzo Durazzo Suites

Hotel Astoria

Hotel Astoria
4.0 star property
San Vincenzo, 1.2 km from Santa Maria di Castello
9.6 out of 10, Exceptional, (482)
"Excellent hotel "
United States
Salvatore
Hotel Astoria

Le Nuvole Residenza d'epoca

Le Nuvole Residenza d'epoca
3.0 star property
Genoa Historical Centre, 0.4 km from Santa Maria di Castello
9.2 out of 10, Wonderful, (245)
"Great stay! "
Norway
Anonymous traveller
The price is 2.241.005 ₫
2.649.988 ₫ total
includes taxes & fees
5 Jan - 6 Jan 2026
Le Nuvole Residenza d'epoca

GLAM TIME

GLAM TIME
San Vincenzo, 0.5 km from Santa Maria di Castello
9.4 out of 10, Exceptional, (33)
"The room was very nicely laid out and authentic. Very nice stay"
United States
Nathaniel
The price is 2.689.122 ₫
3.143.010 ₫ total
includes taxes & fees
6 Jan - 7 Jan 2026
GLAM TIME

B&B Genova Holiday

B&B Genova Holiday
Castelletto, 0.8 km from Santa Maria di Castello
9.4 out of 10, Exceptional, (22)
"Centrally located to walk downtown area. Clean, comfortable bed, quiet, good A/C , Wi-Fi, friendly manager. Our room had our own bathroom, very nice, but down the hall . Included boxed breakfast in the morning."
United States
John
The price is 1.871.939 ₫
2.244.170 ₫ total
includes taxes & fees
24 Dec - 25 Dec
B&B Genova Holiday

Hotel Doria

Hotel Doria
3.0 star property
Genoa Historical Centre, 0.5 km from Santa Maria di Castello
9.2 out of 10, Wonderful, (79)
"Great simple hotel in Genoa for one night"
United Kingdom
Bethan
Hotel Doria

Melia Genova

Melia Genova
5.0 star property
Carignano, 0.8 km from Santa Maria di Castello
9.2 out of 10, Wonderful, (904)
"Staff were very polite and helpful. Was a great stay. Highly recommend. Second time in this awesome hotel"
United States
GARRON
The price is 4.145.891 ₫
4.868.618 ₫ total
includes taxes & fees
4 Jan - 5 Jan 2026
Melia Genova

Queen Catlleya Suite

Queen Catlleya Suite
San Vincenzo, 1.3 km from Santa Maria di Castello
9.6 out of 10, Exceptional, (24)
"Amazing room. Feels like you staying in palace. "
United States
Alex
Queen Catlleya Suite

Happy Family Apartments San Luca

Happy Family Apartments San Luca
Genoa Historical Centre, 0.5 km from Santa Maria di Castello
9.2 out of 10, Wonderful, (17)
"I had a fantastic stay at Genova! The owner was incredibly nice and accommodating throughout my entire visit. Their hospitality made my trip even more enjoyable. I would highly recommend this place to anyone looking for a welcoming and comfortable stay."
United States
Razina
Happy Family Apartments San Luca

B&B Hotel Genova City Center

B&B Hotel Genova City Center
San Vincenzo, 0.8 km from Santa Maria di Castello
9.2 out of 10, Wonderful, (159)
"The staff went out of their way to make sure we had a nice visit, and was very friendly. "
United States
Daniel
The price is 2.003.089 ₫
2.388.281 ₫ total
includes taxes & fees
7 Jan - 8 Jan 2026
B&B Hotel Genova City Center

Hotel De Ville

Hotel De Ville
4.0 star property
Genoa Historical Centre, 0.3 km from Santa Maria di Castello
9.0 out of 10, Wonderful, (245)
"Great hotel, spacious, friendly and welcoming staff, I had a pleasant stay. One remark, the noise isolation is not great so you feel any doors rattle outside, which is quite loud. But I had a great time and appreciate the stuff. Thank you. "
United States
Elena
The price is 2.495.919 ₫
2.992.022 ₫ total
includes taxes & fees
7 Jan - 8 Jan 2026
Hotel De Ville

NH Collection Genova Marina

NH Collection Genova Marina
4.0 star property
Centro Est, 0.6 km from Santa Maria di Castello
9.0 out of 10, Wonderful, (1002)
"Best location!"
Canada
Kayvan
The price is 3.977.784 ₫
4.622.074 ₫ total
includes taxes & fees
24 Dec - 25 Dec
NH Collection Genova Marina

Hotel Continental Genova

Hotel Continental Genova
4.0 star property
Prè, 1.3 km from Santa Maria di Castello
9.2 out of 10, Wonderful, (1001)
"The Guest services were outstanding! We were upgraded to the five star hotel next door, the Grand Savoia…. Beautiful hotel!"
United States
Jennifer
The price is 3.719.228 ₫
4.337.662 ₫ total
includes taxes & fees
23 Dec - 24 Dec
Hotel Continental Genova

Best Western Hotel Metropoli

Best Western Hotel Metropoli
3.0 star property
Genoa Historical Centre, 0.7 km from Santa Maria di Castello
9.0 out of 10, Wonderful, (694)
"Yes everything was excellent."
United States
Peter
The price is 2.325.043 ₫
2.742.430 ₫ total
includes taxes & fees
11 Jan - 12 Jan 2026
Best Western Hotel Metropoli

HNN Luxury Suites

HNN Luxury Suites
3.0 star property
Prè, 1.3 km from Santa Maria di Castello
9.2 out of 10, Wonderful, (466)
"The room we had was large and clean, the towels were bath sheets. Denise who welcomed us was wonderful showing us around and giving us ideas on what to do and see in Genova."
Australia
Lisa
HNN Luxury Suites

Grand Hotel Savoia Genova, Curio Collection by Hilton

Grand Hotel Savoia Genova, Curio Collection by Hilton
5.0 star property
Prè, 1.3 km from Santa Maria di Castello
9.2 out of 10, Wonderful, (1000)
"Beautiful room and property with adjacent restaurants. Friendly and helpful staff. Close to Cruise Port and Airport. The price was very reasonable, too. We will stay there any time we are in Genoa!"
United States
Tyrell
The price is 4.767.458 ₫
5.552.342 ₫ total
includes taxes & fees
3 Jan - 4 Jan 2026
Grand Hotel Savoia Genova, Curio Collection by Hilton

RIVA SUPERIOR

RIVA SUPERIOR
San Vincenzo, 0.9 km from Santa Maria di Castello
9.0 out of 10, Wonderful, (171)
"Great location, wish I could have stayed longer. "
United States
Tina
The price is 2.200.947 ₫
2.605.924 ₫ total
includes taxes & fees
23 Dec - 24 Dec
RIVA SUPERIOR
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Santa Maria di Castello Hotel Reviews

Hotels near other Santa Maria di Castello attractions

Frequently asked questions

What's the area like around Santa Maria di Castello?
Santa Maria di Castello is located in a historic area of Molo known for its beautiful ocean views and bar scene. If you're looking for a convenient place to stay, take a look at the 1015 hotels and other accommodation options you'll find within a mile.
How many hotels are there near Santa Maria di Castello?
Expedia has 1015 hotels and other accommodation options within a mile from Santa Maria di Castello.
If I need to cancel the hotel reservation for my stay near Santa Maria di Castello, will I receive a refund?
Yes! Most hotel reservations are fully refundable if you cancel prior to the accommodation's cancellation deadline, which is often 24 or 48 hours before check in. If you have a reservation that's non-refundable, it might still be possible to cancel it and receive a refund within a 24-hour period of your booking. Add dates, click "Search", then you can use the "fully refundable" filter to view the best options available near Santa Maria di Castello.
What can I see and do near Santa Maria di Castello?
National Gallery of Palazzo Spinola, Palazzo Rosso and Galata Maritime Museum feature a variety of fascinating exhibits to see while you're in town. Palazzo Ducale, La casa di Cristoforo Colombo and Teatro Carlo Felice are some of the local landmarks to explore. Get outside and spend some time strolling around Villa Brignole Sale Duchessa di Galliera, Biosfera and Strade Nuove.

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