Where to stay in Santa María
Find the best Santa María areas and neighborhoods for the activities you enjoy most. Learn more about Santa María
Oaxaca Centro
7 out of top 10 points of interest in this area
Churches, museums and art galleries are some highlights of Oaxaca Centro. Make a stop by Oaxaca Textile Museum or Oaxaca Cathedral while you're exploring.
Ruta Independencia
While visiting Ruta Independencia, you might make a stop by sights like Oaxaca Ethnobotanical Garden and Andador de Macedonia Alcala.
Jalatlaco
While Jalatlaco isn't home to many top sights, El Llano Park and Oaxaca Ethnobotanical Garden are some notable places to visit nearby.
Reforma
While visiting Reforma, you might make a stop by sights like Plaza Mazari and Plaza Parque.
Santa Lucía del Camino
1 out of top 10 points of interest in this area
While Santa Lucía del Camino isn't home to many top sights, Oaxaca Cultural and Convention Center and El Llano Park are some notable places to visit nearby.
Top hotels in Santa María
Hotel Boutique Naura Centro
Av Hidalgo 918 Oaxaca OAX
Fully refundableReserve now, pay when you stay
3.758.067 ₫
4.472.100 ₫ total
8 Aug - 9 Aug
includes taxes & fees
Hotel Hacienda
Av Eduardo Mata 1918 Oaxaca OAX
Fully refundableReserve now, pay when you stay
1.688.414 ₫
2.009.205 ₫ total
8 Aug - 9 Aug
includes taxes & fees
9/10 Wonderful! (1,005 reviews)
"Maintenance personal outstanding front desk no so much"
Reviewed on 30 Jul 2026
Quinta Real Oaxaca
Calle 5 De Mayo 300 Oaxaca OAX
Fully refundableReserve now, pay when you stay
7.686.186 ₫
9.146.562 ₫ total
7 Sept - 8 Sept
includes taxes & fees
9.6/10 Exceptional! (1,005 reviews)
"Property and grounds were very beautiful! Staff was super helpful. Room was a little bit plain—needs a little more decor to offset the small size and white walls but the grounds and staff made up for it and our stay was otherwise superb!"
Reviewed on 4 Aug 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Frequently asked questions
How much does a Santa María holiday package cost?
Starting from only , a holiday package is your passport to low-cost travel. Custom build your Santa María getaway by choosing from our huge range of flights, hotels and rental cars.
How do I get a cheap travel package to Santa María?
One of the easiest ways to save dollars (and time) is to combine your bookings with Expedia. Hotels, flights, rental cars and activities — we've got everything you need. Pick a combination that suits your style and see your savings pile up. Of course, a package deal is never a one-size-fits-all. That's why we offer more than 550 partner airlines and 1null000null000 hotel options from all over the world, which lets you customize your Santa María getaway.
Where should I stay in Santa María?
With fascinating attractions such as Zocalo Square and Church of Santo Domingo de Guzman in this neighbourhood, try to find a hotel near them. Auditorio Guelaguetza is another Santa María sight that draws the crowds.
How far in advance should I book my Santa María holiday?
Travellers are generally able to compare international airfares on Expedia within 12 months of departure. Booking late? With a stroke of luck, it's still possible to purchase a cheaper ticket only weeks before your flight.
What does an Expedia Santa María travel package include?
Choose from any combination of hotels, rental cars and flights. Once you've made your booking, you can add tours and activities. Want to pick your fare class? That's easily done too. The choice is all yours when it comes to planning your perfect Santa Marían escape.
What should I know before booking a Santa María travel package?
You can save a tidy sum by combining your hotels, airfares and rental cars. Once you've made your booking, add on fun stuff like activities or sightseeing tours. Your next awesome adventure is only a couple of clicks away.
Can I choose my airline with a Santa Marían Expedia holiday package?
Yes, definitely. Expedia has more than 550 partner airlines to choose from across the world. With such a huge range of choice, finding the perfect carrier to bring you to Santa María won't be hard.
If I'm not able to travel, can I cancel my Santa María holiday package?
Don't stress if you're rethinking your Santa María holiday package — it's possible to change or amend your booking. And if you've booked it within 24 hours, you may be able to do it at no cost. However, bookings made more than 24 hours ago may incur fees from your airline, hotel or car rental company. We realise your circumstances can change suddenly, so look up our Customer Service Portal if that occurs. When you're ready to make changes, we'll be here to help.