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Our top choices for Santa Prisca hotels

Palazzo Velabro, a Member of Design Hotels

Palazzo Velabro, a Member of Design Hotels
4.0 star property
0.7 km from Santa Prisca
9.8 out of 10, Exceptional, (68)
"Absolutely perfect location and hotel was very clean and staff exceptional!"
United States
TIMOTHY
The price is 5.626.729 ₫
6.653.607 ₫ total
includes taxes & fees
12 Jan - 13 Jan 2026
Palazzo Velabro, a Member of Design Hotels

Giuditta in Trastevere

Giuditta in Trastevere
Trastevere, 1.2 km from Santa Prisca
9.6 out of 10, Exceptional, (263)
"Clean room, good location and fantastic staff "
United States
alberto
Giuditta in Trastevere

Hotel Smeraldo

Hotel Smeraldo
3.0 star property
Sant'Eustachio, 1.5 km from Santa Prisca
9.6 out of 10, Exceptional, (1003)
"We have stayed here before and they staff and facility are top notch. Definitely recommend this hotel.."
Canada
Terry
The price is 3.572.832 ₫
4.301.634 ₫ total
includes taxes & fees
21 Dec - 22 Dec
Hotel Smeraldo

Hotel Chapter Roma

Hotel Chapter Roma
4.0 star property
Regola, 1.3 km from Santa Prisca
9.6 out of 10, Exceptional, (745)
"Beautiful room and great service. Breakfast is super delicious!"
Canada
Yifan
The price is 3.950.015 ₫
4.809.221 ₫ total
includes taxes & fees
23 Dec - 24 Dec
Hotel Chapter Roma

Radisson Collection Hotel, Roma Antica

Radisson Collection Hotel, Roma Antica
5.0 star property
Pigna, 1.4 km from Santa Prisca
9.6 out of 10, Exceptional, (147)
"Clean, good breakfast, walkable to major historical ruins"
Canada
Pam
The price is 6.442.605 ₫
7.705.805 ₫ total
includes taxes & fees
12 Jan - 13 Jan 2026
Radisson Collection Hotel, Roma Antica

Navona Style

Navona Style
Pigna, 1.5 km from Santa Prisca
9.6 out of 10, Exceptional, (228)
"Excellent location, wonderful room and the best staff! "
United States
Ruth D
The price is 3.898.723 ₫
4.597.857 ₫ total
includes taxes & fees
18 Dec - 19 Dec
Navona Style

H10 Palazzo Galla

H10 Palazzo Galla
4.0 star property
Trevi, 1.5 km from Santa Prisca
9.6 out of 10, Exceptional, (385)
"It was a good option for our last night stay."
United States
Iryna
The price is 5.953.079 ₫
7.012.592 ₫ total
includes taxes & fees
8 Jan - 9 Jan 2026
H10 Palazzo Galla

Colosseo Accomodation Room Guest House

Colosseo Accomodation Room Guest House
Monti, 1.5 km from Santa Prisca
9.6 out of 10, Exceptional, (52)
"Most excellent, comfy bed and super close to the colosseum! "
United States
Robert
The price is 2.110.024 ₫
2.754.285 ₫ total
includes taxes & fees
24 Dec - 25 Dec
Colosseo Accomodation Room Guest House

Seven Suites

Seven Suites
0.8 km from Santa Prisca
9.4 out of 10, Exceptional, (337)
"The property was extremely clean and staff very friendly. "
United States
Diane
Seven Suites

The Inn at the Roman Forum Luxury Collection - The Inn At The Roman Forum

The Inn at the Roman Forum Luxury Collection - The Inn At The Roman Forum
Monti, 1.3 km from Santa Prisca
9.4 out of 10, Exceptional, (276)
"Staff was so nice "
United States
Ann Marie
The price is 6.208.927 ₫
7.263.078 ₫ total
includes taxes & fees
19 Dec - 20 Dec
The Inn at the Roman Forum Luxury Collection - The Inn At The Roman Forum

Otivm Hotel

Otivm Hotel
4.0 star property
Campitelli, 1.4 km from Santa Prisca
9.4 out of 10, Exceptional, (758)
"Clean rooms, great location, staff was very friendly and accommodating. Roof top bar was a nice bonus."
United States
Kristen
Otivm Hotel

Room Mate Collection Mia, Rome Colosseum

Room Mate Collection Mia, Rome Colosseum
4.0 star property
1.3 km from Santa Prisca
9.4 out of 10, Exceptional, (1001)
"The room was beautiful and staff were incredibly helpful! "
United Kingdom
Giulia
The price is 4.824.485 ₫
5.770.826 ₫ total
includes taxes & fees
14 Jan - 15 Jan 2026
Room Mate Collection Mia, Rome Colosseum

NH Collection Roma Fori Imperiali

NH Collection Roma Fori Imperiali
5.0 star property
Monti, 1.5 km from Santa Prisca
9.4 out of 10, Exceptional, (212)
"Location"
United States
Trevon
The price is 11.816.131 ₫
13.616.684 ₫ total
includes taxes & fees
5 Jan - 6 Jan 2026
NH Collection Roma Fori Imperiali

Top Floor Colosseo

Top Floor Colosseo
Monti, 1.6 km from Santa Prisca
9.4 out of 10, Exceptional, (357)
"Clean room, Great Staff, Good breakfast "
United States
Robert
The price is 2.656.840 ₫
3.355.492 ₫ total
includes taxes & fees
24 Dec - 25 Dec
Top Floor Colosseo

The Talent Hotel

The Talent Hotel
4.0 star property
Trevi, 1.6 km from Santa Prisca
9.4 out of 10, Exceptional, (355)
"This was my wife and I first visit to Rome and we enjoyed our stay at the Talent Hotel!"
United States
albert
The price is 4.045.455 ₫
7.975.555 ₫ total
includes taxes & fees
22 Dec - 23 Dec
The Talent Hotel

Relais Le Clarisse a Trastevere

Relais Le Clarisse a Trastevere
Trastevere, 1.1 km from Santa Prisca
9.2 out of 10, Wonderful, (664)
"Everything was perfect, cleanliness, comfort and location. But what really made our stay was the friendliness of staff, so welcoming and helpful! I would happily recommend "
United Kingdom
Dawn
The price is 2.278.460 ₫
2.939.564 ₫ total
includes taxes & fees
6 Jan - 7 Jan 2026
Relais Le Clarisse a Trastevere

Hotel Monte Cenci

Hotel Monte Cenci
4.0 star property
Regola, 1.2 km from Santa Prisca
9.2 out of 10, Wonderful, (901)
"Beautiful place to stay!"
United States
Gabriel
Hotel Monte Cenci

Little Queen Suite

Little Queen Suite
1.3 km from Santa Prisca
9.2 out of 10, Wonderful, (332)
"Lovely staff, comfortable room, great location. "
United States
Stephanie
The price is 2.627.155 ₫
3.261.235 ₫ total
includes taxes & fees
11 Jan - 12 Jan 2026
Little Queen Suite

Hotel Ponte Sisto

Hotel Ponte Sisto
4.0 star property
Regola, 1.5 km from Santa Prisca
9.2 out of 10, Wonderful, (1003)
"Hotel is very clean, breakfast was great with lots of variety, they do have a rooftop bar where you can get great views of the city at night. Walkable to various shops and restaurants. "
United States
Stephanie
The price is 4.706.403 ₫
5.640.937 ₫ total
includes taxes & fees
7 Jan - 8 Jan 2026
Hotel Ponte Sisto

Numa Rome Verso

Numa Rome Verso
1.4 km from Santa Prisca
9.2 out of 10, Wonderful, (73)
"Easy check in and loved the location. Apartment was super clean. Would stay again"
United States
Daniel
The price is 3.938.710 ₫
4.703.945 ₫ total
includes taxes & fees
12 Jan - 13 Jan 2026
Numa Rome Verso
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Santa Prisca Hotel Reviews

Hotels near other Santa Prisca attractions

Frequently asked questions

What's the area like around Santa Prisca?
Santa Prisca is located in a historic area of Rome known for its stunning cathedral and notable monuments. If you're looking for a convenient place to stay, take a look at the 853 hotels and other accommodation options you'll find within a mile.
How many hotels should I expect to find close to Santa Prisca?
Expedia has 853 hotels and other accommodation options within a mile from Santa Prisca.
If I need to cancel the hotel reservation for my stay near Santa Prisca, will I receive a refund?
Yes, you'll find most room reservations are fully refundable if cancelled before the hotel's cancellation deadline, which is often 24 or 48 hours before the scheduled arrival. If your reservation is non-refundable, you might still have the option to cancel and get a refund within 24 hours of your booking. Add your dates and click on "Search", then use the "fully refundable" filter to review the top deals on offer near Santa Prisca.
What can I see and do near Santa Prisca?
You'll want to browse the collections at Vatican Museums, Capitoline Museum and Trajan's Market. Sights like Colosseum, Pantheon and Piazza Navona are landmarks to visit in the area. You can check out the local talent at Teatro Brancaccio, Teatro dell'Opera di Roma and Sistina Theater.
How can I get to Santa Prisca?
With so many choices for transport, exploring the area around Santa Prisca is a breeze. You can walk to nearby metro stations including Venezia Tram Stop, Colosseo Station and Cavour Station. If you're taking a train into town, Rome Termini Station and Rome (XRJ-Termini Rail Station) are the closest stops to Rome Historic Centre.