Santee Holidays
Book a Hotel + Flight or Car together to unlock savings
Top hotels in Santee
Tru By Hilton Santee
263 Britain St. and 273 Britain St. Santee SC
Fully refundableReserve now, pay when you stay
The price is 2.854.274 ₫ per night from 5 Mar to 6 Mar
2.854.274 ₫
3.168.244 ₫ total
5 Mar - 6 Mar
includes taxes & fees
9.2/10 Wonderful! (735 reviews)
Yes
Reviewed on 25 Feb 2026
Baymont by Wyndham Santee
249 Britain Street Santee SC
Fully refundableReserve now, pay when you stay
The price is 2.087.899 ₫ per night from 3 Mar to 4 Mar
2.087.899 ₫
2.317.567 ₫ total
3 Mar - 4 Mar
includes taxes & fees
8/10 Very Good! (1,425 reviews)
Room clean. Convenient location. Quick check in.
Reviewed on 25 Feb 2026
Fairfield Inn & Suites by Marriott Santee
9074 Old Number Six Hwy Santee SC
Fully refundableReserve now, pay when you stay
The price is 3.262.750 ₫ per night from 22 Mar to 23 Mar
3.262.750 ₫
3.621.653 ₫ total
22 Mar - 23 Mar
includes taxes & fees
9.8/10 Exceptional! (1,003 reviews)
This will definitely be our new place to stay on our way back-and-forth to North Carolina from Florida!
Reviewed on 25 Feb 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Popular places to visit
Santee State Park
You can take time to visit Santee State Park during your travels to Santee. While you're here, you can savour the top-notch restaurants.
Santee Cooper Country Club
Enjoy a round of golf in Santee at Santee Cooper Country Club. While you're here, you can savour the top-notch restaurants.
