Santee Holidays
Book a Hotel + Flight or Car together to unlock savings
Top hotels in Santee
Tru By Hilton Santee
263 Britain St. and 273 Britain St. Santee SC
Fully refundableReserve now, pay when you stay
The price is 2.810.462 ₫ per night from 26 Jan to 27 Jan
2.810.462 ₫
3.119.613 ₫ total
26 Jan - 27 Jan
includes taxes & fees
9/10 Wonderful! (666 reviews)
This is a very nice hotel. Seems newer. Good location by the highway. Nice amenities and breakfast.
Reviewed on 5 Jan 2026
Baymont by Wyndham Santee
249 Britain Street Santee SC
Fully refundableReserve now, pay when you stay
The price is 1.969.687 ₫ per night from 12 Jan to 13 Jan
1.969.687 ₫
2.186.354 ₫ total
12 Jan - 13 Jan
includes taxes & fees
7.8/10 Good! (1,431 reviews)
Good bagels and coffee!
Reviewed on 5 Jan 2026
Hampton Inn Santee-I-95
9060 Old Number Six Hwy Santee SC
Fully refundableReserve now, pay when you stay
The price is 3.383.061 ₫ per night from 25 Jan to 26 Jan
3.383.061 ₫
3.755.198 ₫ total
25 Jan - 26 Jan
includes taxes & fees
9.6/10 Exceptional! (1,000 reviews)
The front desk gal was fabulous. Place is great.
Reviewed on 6 Jan 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Popular places to visit
Santee State Park
You can take time to visit Santee State Park during your travels to Santee. While you're here, you can savour the top-notch restaurants.
Santee Cooper Country Club
Enjoy a round of golf in Santee at Santee Cooper Country Club. While you're here, you can savour the top-notch restaurants.
