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Our top choices for Santiago hotels

Living Up

Living Up
3.0 star property
Santiago
The price is 1.231.922 ₫
1.684.973 ₫ total
includes taxes & fees
22 Dec - 23 Dec
Living Up

Camino Real Puebla Angelopolis

Camino Real Puebla Angelopolis
4.0 star property
Angelópolis, 5.3 km from Santiago
8.2 out of 10, Very good, (2072)
"Clean and courteous."
United States
Ninette
The price is 1.557.374 ₫
1.853.275 ₫ total
includes taxes & fees
14 Dec - 15 Dec
Camino Real Puebla Angelopolis

Hotel Las Iglesias, Cholula

Hotel Las Iglesias, Cholula
3.0 star property
10.7 km from Santiago
8.8 out of 10, Excellent, (541)
"The room was excellent and the staff were very friendly and helpful. We truly loved this hotel. "
United States
Rogelio
Hotel Las Iglesias, Cholula

La Quinta by Wyndham Puebla Palmas Angelopolis

La Quinta by Wyndham Puebla Palmas Angelopolis
3.0 star property
Angelópolis, 2.6 km from Santiago
8.6 out of 10, Excellent, (1353)
"I love the hotel"
Mexico
Victor
The price is 1.578.444 ₫
1.878.348 ₫ total
includes taxes & fees
11 Jan - 12 Jan 2026
La Quinta by Wyndham Puebla Palmas Angelopolis

Palacio Julio Hotel

Palacio Julio Hotel
5.0 star property
Puebla Historic Center, 1.7 km from Santiago
9.6 out of 10, Exceptional, (238)
"Amazing stay. Great hotel "
United States
Ashley
Palacio Julio Hotel

InterContinental Presidente Puebla by IHG

InterContinental Presidente Puebla by IHG
4.0 star property
2.1 km from Santiago
9.0 out of 10, Wonderful, (1005)
"awesome breakfast, great location, beautiful hotel"
United States
Andy
The price is 2.209.788 ₫
2.629.648 ₫ total
includes taxes & fees
21 Dec - 22 Dec
InterContinental Presidente Puebla by IHG

Holiday Inn Express Puebla by IHG

Holiday Inn Express Puebla by IHG
3.5 star property
2 km from Santiago
9.4 out of 10, Exceptional, (1645)
"Clean, secure, free parking and breakfast. "
United States
Kenneth
The price is 1.605.127 ₫
1.910.101 ₫ total
includes taxes & fees
23 Dec - 24 Dec
Holiday Inn Express Puebla by IHG

City Express Junior by Marriott Puebla Angelopolis

City Express Junior by Marriott Puebla Angelopolis
3.0 star property
La Noria, 1.8 km from Santiago
8.6 out of 10, Excellent, (942)
"Excelente "
Mexico
Carlos Samuel
The price is 1.178.140 ₫
1.401.982 ₫ total
includes taxes & fees
3 Jan - 4 Jan 2026
City Express Junior by Marriott Puebla Angelopolis

Hotel Del Portal, Puebla

Hotel Del Portal, Puebla
3.5 star property
Puebla Historic Center, 1.6 km from Santiago
8.0 out of 10, Very good, (1003)
"Excelente "
Mexico
Edgar joshue
The price is 1.012.601 ₫
1.205.001 ₫ total
includes taxes & fees
26 Dec - 27 Dec
Hotel Del Portal, Puebla

HOTEL BOUTIQUE CASONA 65

HOTEL BOUTIQUE CASONA 65
4.0 star property
Puebla Historic Center, 1.4 km from Santiago
9.6 out of 10, Exceptional, (256)
"Great place to stay at. The staff is very friendly and helpful with any questions or concerns. It’s close by the central historical park. Would recommend the hotel to anyone traveling to Puebla."
United States
Lucia
The price is 1.992.569 ₫
2.371.157 ₫ total
includes taxes & fees
15 Dec - 16 Dec
HOTEL BOUTIQUE CASONA 65

Plaza Poblana

Plaza Poblana
3.5 star property
3.3 km from Santiago
8.0 out of 10, Very good, (655)
"great facility, affordable and breakfast buffet is amazing"
United States
Luis A
Plaza Poblana

City Express by Marriott Puebla Angelopolis

City Express by Marriott Puebla Angelopolis
3.0 star property
La Noria, 1.8 km from Santiago
8.4 out of 10, Very good, (1002)
"Excelente "
Mexico
Gerardo
The price is 1.388.092 ₫
1.651.821 ₫ total
includes taxes & fees
8 Jan - 9 Jan 2026
City Express by Marriott Puebla Angelopolis

Hotel Villa Florida

Hotel Villa Florida
3.5 star property
Angelópolis, 3.1 km from Santiago
8.8 out of 10, Excellent, (607)
"Great location, staff very friendly. A bit noisy (cars) but in a fair trade for its location. "
Canada
Mayra Patricia
Hotel Villa Florida

Hotel 5 de Mayo

Hotel 5 de Mayo
3.0 star property
Xanenetla, 2.4 km from Santiago
9.4 out of 10, Exceptional, (1000)
"It is clean and confortable"
United States
Prudencio
The price is 1.512.383 ₫
1.799.736 ₫ total
includes taxes & fees
14 Dec - 15 Dec
Hotel 5 de Mayo

Holiday Inn Express Hotel & Suites Puebla Angelopolis by IHG

Holiday Inn Express Hotel & Suites Puebla Angelopolis by IHG
3.0 star property
Angelópolis, 5.3 km from Santiago
9.4 out of 10, Exceptional, (1001)
"Good hotel "
United States
Yamilka
The price is 1.540.864 ₫
1.833.628 ₫ total
includes taxes & fees
11 Jan - 12 Jan 2026
Holiday Inn Express Hotel & Suites Puebla Angelopolis by IHG

Holiday Inn Puebla La Noria by IHG

Holiday Inn Puebla La Noria by IHG
3.5 star property
La Noria, 1.6 km from Santiago
9.2 out of 10, Wonderful, (1001)
"Great place "
United States
Hugo
The price is 1.559.851 ₫
1.856.223 ₫ total
includes taxes & fees
5 Jan - 6 Jan 2026
Holiday Inn Puebla La Noria by IHG

Cartesiano Boutique & Wellness Hotel

Cartesiano Boutique & Wellness Hotel
4.5 star property
Puebla Historic Center, 1.9 km from Santiago
9.6 out of 10, Exceptional, (713)
"Staff was very friendly "
United States
Kenneth
The price is 3.267.548 ₫
3.888.382 ₫ total
includes taxes & fees
11 Jan - 12 Jan 2026
Cartesiano Boutique & Wellness Hotel

NH Puebla Centro Histórico

NH Puebla Centro Histórico
4.0 star property
Puebla Historic Center, 1.1 km from Santiago
8.6 out of 10, Excellent, (1488)
"Excellent option to stay in downtown, great location for visiting major points of interest and museums. The staff is very friendly. "
United States
LUZ
The price is 1.573.948 ₫
1.872.998 ₫ total
includes taxes & fees
21 Dec - 22 Dec
NH Puebla Centro Histórico

Casa Pepe Hostel Boutique - Puebla

Casa Pepe Hostel Boutique - Puebla
4.0 star property
Puebla Historic Center, 1.9 km from Santiago
9.2 out of 10, Wonderful, (746)
"The rooms are very clean and the staff is very friendly, good and healthy options for breakfast."
United States
hector
The price is 1.456.898 ₫
1.733.713 ₫ total
includes taxes & fees
6 Jan - 7 Jan 2026
Casa Pepe Hostel Boutique - Puebla

Ikonik Hotel Puebla

Ikonik Hotel Puebla
4.0 star property
Barrio de la Luz, 2.1 km from Santiago
8.6 out of 10, Excellent, (698)
"Clean room"
United States
Luis
The price is 1.210.122 ₫
1.440.045 ₫ total
includes taxes & fees
4 Jan - 5 Jan 2026
Ikonik Hotel Puebla
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Santiago

Find the best Santiago areas for the activities you enjoy most.

Puebla Historic Center

Travellers come to Puebla Historic Center for its abundant dining options, and you can see top attractions like Zócalo de Puebla and Los Sapos Bazaar while you're in town.

Cholula

You'll enjoy the archaeological sites and museums in Cholula. You might want to make time for a stop at Zócalo or Plaza de la Concordia.

Angelópolis

Angelópolis is noteworthy for its shopping, and you can make a stop at top attractions like Angelopolis Commercial Center and Metropolitan Auditorium.

Cholula Centro

If you're spending some time in Cholula Centro, Zócalo and San Gabriel Convent are top sights worth seeing.

Lomas de Angelópolis

While Lomas de Angelópolis may not have many sights to explore, venturing just a little farther will lead you to top things to see and do like International Baroque Museum and Museo de Artes Populares.

Top Santiago Hotel Reviews

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Frequently asked questions

What's it like in Santiago?
You'll be sure to have fun exploring Puebla's Santiago neighbourhood.
If I need to cancel my hotel reservation in Santiago, will I receive a refund?
Yes! The majority of hotel reservations are fully refundable if you cancel prior to the accommodation's cancellation deadline, which is usually within 24-48 hours of check in. If your reservation is non-refundable, you might be able to still cancel and receive a refund within a 24-hour period of your booking. Put your dates in and click on "Search", then filter by "fully refundable" to get top deals in Santiago.
What is there to do in this Puebla neighbourhood?
Plaza de Revolución, Museum of the Mexican Army and Air Force and Uriarte Talavera are just a few of the places to visit in and around Santiago. Profetica and Bello Museum are also worth a visit when you're out sightseeing in Puebla.