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12 Dec - 13 Dec
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13 Dec - 14 Dec
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12 Dec - 14 Dec
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19 Dec - 21 Dec

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Our top choices for Santo Domingo hotels

Suite, 1 King Bed with Sofa bed | Private kitchenette | Mini-fridge, coffee/tea maker
Brownwood Hotel & Spa

Brownwood Hotel & Spa

Brownwood Hotel & Spa
3.0 star property
12.4 km from Santo Domingo
9.8 out of 10, Exceptional, (1067)
"Front desk check in staff very friendly, room spotless and comfortable. "
United States
Kristine
Brownwood Hotel & Spa
Property amenity
Best Western Ocala Park Centre

Best Western Ocala Park Centre

Best Western Ocala Park Centre
2.5 star property
30.8 km from Santo Domingo
8.4 out of 10, Very good, (1209)
"Quiet and clean older hotel."
United States
John
The price is 1.767.992 ₫
1.971.311 ₫ total
includes taxes & fees
15 Dec - 16 Dec
Best Western Ocala Park Centre
Exterior
Comfort Inn & Suites Tavares North

Comfort Inn & Suites Tavares North

Comfort Inn & Suites Tavares North
2.5 star property
28.8 km from Santo Domingo
8.2 out of 10, Very good, (1005)
"Very clean and the lady at the front desk was very friendly "
United States
Adolfo
The price is 2.373.296 ₫
2.634.359 ₫ total
includes taxes & fees
15 Dec - 16 Dec
Comfort Inn & Suites Tavares North
Lobby sitting area
avid Hotel Ocala Downtown by IHG

avid Hotel Ocala Downtown by IHG

avid Hotel Ocala Downtown by IHG
2.5 star property
29.9 km from Santo Domingo
8.8 out of 10, Excellent, (770)
"Nice, clean affordable hotel"
United States
Barbara
The price is 2.106.320 ₫
2.348.547 ₫ total
includes taxes & fees
21 Dec - 22 Dec
avid Hotel Ocala Downtown by IHG
Free daily buffet breakfast
Holiday Inn Express Hotel & Suites Tavares - Leesburg by IHG

Holiday Inn Express Hotel & Suites Tavares - Leesburg by IHG

Holiday Inn Express Hotel & Suites Tavares - Leesburg by IHG
2.5 star property
24.9 km from Santo Domingo
8.8 out of 10, Excellent, (1001)
"Nice, clean and great accessibility in the room. Staff was professional and attentive. Would stay again if I return to the area."
United States
Marlene
The price is 2.580.242 ₫
2.864.068 ₫ total
includes taxes & fees
17 Dec - 18 Dec
Holiday Inn Express Hotel & Suites Tavares - Leesburg by IHG
Front of property – evening/night
The Waterfront Inn

The Waterfront Inn

The Waterfront Inn
3.0 star property
4.2 km from Santo Domingo
9.2 out of 10, Wonderful, (1281)
"Great hotel "
United States
sherry
The Waterfront Inn
Front of property – evening/night
Microtel Inn & Suites by Wyndham Leesburg/Mt Dora

Microtel Inn & Suites by Wyndham Leesburg/Mt Dora

Microtel Inn & Suites by Wyndham Leesburg/Mt Dora
2.0 star property
21.8 km from Santo Domingo
8.4 out of 10, Very good, (1002)
"Price and location is great, great staff can be updated but overall ok for the value "
United States
Yrani
The price is 1.924.913 ₫
2.136.653 ₫ total
includes taxes & fees
15 Dec - 16 Dec
Microtel Inn & Suites by Wyndham Leesburg/Mt Dora
Lobby
Equus Inn Ocala

Equus Inn Ocala

Equus Inn Ocala
2.5 star property
30.7 km from Santo Domingo
9.0 out of 10, Wonderful, (1745)
"Great place to stay, clean and convinient location. "
United States
Anuj
Equus Inn Ocala
Exterior
Holiday Inn Hotel and Suites Ocala Conference Center by IHG

Holiday Inn Hotel and Suites Ocala Conference Center by IHG

Holiday Inn Hotel and Suites Ocala Conference Center by IHG
3.0 star property
30.9 km from Santo Domingo
8.4 out of 10, Very good, (1002)
"I've been staying at this hotel for years and it never disappoints. "
United States
Angel
The price is 2.580.242 ₫
2.876.970 ₫ total
includes taxes & fees
15 Dec - 16 Dec
Holiday Inn Hotel and Suites Ocala Conference Center by IHG
Outdoor pool
Hilton Ocala

Hilton Ocala

Hilton Ocala
3.5 star property
30.4 km from Santo Domingo
8.6 out of 10, Excellent, (1002)
"Great stay"
United States
cindy
The price is 2.569.184 ₫
2.864.641 ₫ total
includes taxes & fees
21 Dec - 22 Dec
Hilton Ocala
View from room
SureStay Plus Hotel by Best Western The Villages

SureStay Plus Hotel by Best Western The Villages

SureStay Plus Hotel by Best Western The Villages
2.5 star property
2.1 km from Santo Domingo
8.2 out of 10, Very good, (672)
"Will stay again "
United States
Alan
The price is 1.990.472 ₫
2.209.424 ₫ total
includes taxes & fees
14 Dec - 15 Dec
SureStay Plus Hotel by Best Western The Villages
Free daily buffet breakfast
Hampton Inn & Suites Lady Lake/The Villages

Hampton Inn & Suites Lady Lake/The Villages

Hampton Inn & Suites Lady Lake/The Villages
3.0 star property
3.4 km from Santo Domingo
9.0 out of 10, Wonderful, (1000)
"Room was great, staff was very friendly, breakfast was spot on. "
United States
Beth
The price is 2.679.502 ₫
2.867.067 ₫ total
includes taxes & fees
18 Dec - 19 Dec
Hampton Inn & Suites Lady Lake/The Villages
Premium bedding, desk, iron/ironing board, cots/infant beds
Comfort Inn Ocala Silver Springs

Comfort Inn Ocala Silver Springs

Comfort Inn Ocala Silver Springs
2.5 star property
30.3 km from Santo Domingo
8.2 out of 10, Very good, (1001)
"Was great as always.. ty so much "
United States
Jacqueline
The price is 1.879.891 ₫
2.096.078 ₫ total
includes taxes & fees
21 Dec - 22 Dec
Comfort Inn Ocala Silver Springs
Exterior
Mission Resort and Club

Mission Resort and Club

Mission Resort and Club
4.0 star property
30.8 km from Santo Domingo
8.8 out of 10, Excellent, (719)
"Great place to stay ! We came for a wedding and it was fantastic!"
United States
Yasunari
Mission Resort and Club
Fitness facility
Holiday Inn Express & Suites Wildwood The Villages by IHG

Holiday Inn Express & Suites Wildwood The Villages by IHG

Holiday Inn Express & Suites Wildwood The Villages by IHG
3.5 star property
13.9 km from Santo Domingo
9.4 out of 10, Exceptional, (1003)
"The room was very nice and clean, parking was easy and staff very friendly and helpful. I would stay here again!"
United States
Pauline
The price is 2.975.177 ₫
3.183.439 ₫ total
includes taxes & fees
4 Jan - 5 Jan 2026
Holiday Inn Express & Suites Wildwood The Villages by IHG
Lobby sitting area
Sleep Inn and Suites - Ocala / Belleview

Sleep Inn and Suites - Ocala / Belleview

Sleep Inn and Suites - Ocala / Belleview
2.5 star property
19.8 km from Santo Domingo
8.0 out of 10, Very good, (1004)
"Very nice room very clean very welcome and staffing"
United States
william
The price is 1.853.562 ₫
2.066.827 ₫ total
includes taxes & fees
28 Dec - 29 Dec
Sleep Inn and Suites - Ocala / Belleview
Standard Room, 2 Queen Beds | In-room safe, desk, blackout curtains, soundproofing
Microtel Inn & Suites by Wyndham Ocala

Microtel Inn & Suites by Wyndham Ocala

Microtel Inn & Suites by Wyndham Ocala
2.0 star property
19.9 km from Santo Domingo
7.0 out of 10, Good, (1004)
"Nice to hsve hottun"
United States
Elicia
The price is 1.483.573 ₫
2.047.803 ₫ total
includes taxes & fees
18 Dec - 19 Dec
Microtel Inn & Suites by Wyndham Ocala
Room amenity
La Bella Inn

La Bella Inn

La Bella Inn
2.0 star property
28.1 km from Santo Domingo
7.4 out of 10, Good, (347)
"No frills motel. Clean and nice for a short stay "
United States
kathryn
The price is 1.871.992 ₫
2.077.885 ₫ total
includes taxes & fees
14 Dec - 15 Dec
La Bella Inn
Terrace/patio
SpringHill Suites by Marriott Ocala

SpringHill Suites by Marriott Ocala

SpringHill Suites by Marriott Ocala
2.5 star property
30.9 km from Santo Domingo
9.2 out of 10, Wonderful, (660)
"Staff, spacious clean rooms, fire pit, and the breakfast area and options."
United States
Audrey
The price is 3.080.493 ₫
3.434.750 ₫ total
includes taxes & fees
21 Dec - 22 Dec
SpringHill Suites by Marriott Ocala
Property amenity
TownePlace Suites by Marriott Leesburg

TownePlace Suites by Marriott Leesburg

TownePlace Suites by Marriott Leesburg
3.0 star property
18.9 km from Santo Domingo
9.2 out of 10, Wonderful, (338)
"Beautiful hotel"
United States
Lori
The price is 3.054.164 ₫
3.390.122 ₫ total
includes taxes & fees
17 Dec - 18 Dec
TownePlace Suites by Marriott Leesburg
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Where to stay in Santo Domingo

Find the best Santo Domingo areas for the activities you enjoy most.

Silver Lake

While Silver Lake isn't home to many top sights, Spanish Springs Town Square and Lakes Of Lady Lake Golf Club are some notable places to visit nearby.

Del Mar

Though Del Mar may not have many top sights, you can venture to the surrounding area to see attractions like Spanish Springs Town Square and Spanish Springs Lanes.

Mira Mesa

While Mira Mesa may not have many sights to explore, venturing just a little farther will lead you to top things to see and do like Spanish Springs Town Square and The Villages Market Square.

El Cortez

While El Cortez may not have many sights to explore, venturing just a little farther will lead you to top things to see and do like Spanish Springs Town Square and Spanish Springs Lanes.

De La Vista

While De La Vista may not have many sights to explore, venturing just a little farther will lead you to top things to see and do like Spanish Springs Town Square and The Villages Market Square.

Top Santo Domingo Hotel Reviews

Mission Resort and Club

Mission Resort and Club

10/10 Excellent
"The room was spotless, the bed very comfortable and plenty of extra pillows. The staff went above and beyond from the front desk to the trolly drivers. The waitresses we had for dinner and lunch were excellent. "
Norma L. 1-night trip
Posted 4 days ago
Mission Resort and Club

Explore a world of travel with Expedia

Frequently asked questions

What is Santo Domingo like?
Travellers are sure to enjoy a stay in Lady Lake's Santo Domingo neighbourhood.
How many hotels can I expect to find in the Santo Domingo area?
Expedia has 25 hotels and other accommodation options in Santo Domingo to choose from, making this an ideal home base for exploring the greater Lady Lake area.
If I need to cancel my hotel reservation in Santo Domingo, will I receive a refund?
Yes, most hotel room reservations are fully refundable as long as you cancel before the hotel's cancellation deadline, which often is within 24-48 hours of check in. If you have a non-refundable reservation, it may still be possible to cancel it and get a refund within a 24-hour period of booking. Plug in your dates, click on "Search", then you can filter by "fully refundable" to get the best deals in Santo Domingo.
What is there to do around this Lady Lake neighbourhood?
Spanish Springs Town Square, Spanish Springs Lanes and Orange Blossom Hills Golf & Country Club are just a few of the places to visit in and around Santo Domingo. While you're out sightseeing, Fiesta Bowl and Glenview Champions Country Club are a couple of additional sights to visit in Lady Lake.