Santo Tomas Holidays

Book a Hotel + Flight or Car together to unlock savings

Where to stay in Santo Tomas

Find the best Santo Tomas areas and neighborhoods for the activities you enjoy most. Learn more about Santo Tomas
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Roma Norte

Known for its fascinating museums and popular shops, there's plenty to explore in Roma Norte. Check out top attractions like Avenida Insurgentes and MUCA Roma, and jump on the metro at Insurgentes Station or Sevilla Station to see more of the city.

Find hotels in Roma Norte

Top hotels in Santo Tomas

Fiesta Americana Reforma

Fiesta Americana Reforma

4 out of 5
Paseo De La Reforma 80 Mexico City CDMX
Fully refundableReserve now, pay when you stay
The price is 3.015.911 ₫ per night from 7 Feb to 8 Feb
3.015.911 ₫
3.604.014 ₫ total
7 Feb - 8 Feb
includes taxes & fees
9.2/10 Wonderful! (4,208 reviews)
Amazing buffet breakfast, we had a room update, complimentary food, excellent and warm service.

Reviewed on 12 Jan 2026

Fiesta Americana Reforma
Camino Real Aeropuerto Mexico

Camino Real Aeropuerto Mexico

4 out of 5
Mexico City
Fully refundable
The price is 3.520.314 ₫ per night from 28 Jan to 29 Jan
3.520.314 ₫
4.206.775 ₫ total
28 Jan - 29 Jan
includes taxes & fees
8.6/10 Excellent! (11,994 reviews)
Very good buffet breakfast

Reviewed on 11 Jan 2026

Camino Real Aeropuerto Mexico
Historico Central Hotel

Historico Central Hotel

4 out of 5
Simón Bolívar No. 28 Mexico City Mexico City
Fully refundableReserve now, pay when you stay
The price is 3.901.244 ₫ per night from 1 Feb to 2 Feb
3.901.244 ₫
4.661.987 ₫ total
1 Feb - 2 Feb
includes taxes & fees
9.8/10 Exceptional! (2,411 reviews)
Perfect location, excellent service, rooms very clean. Noemi was very friendly.

Reviewed on 10 Jan 2026

Historico Central Hotel
See all 6,381 properties in Santo Tomas
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a Santo Tomas holiday package cost?
From as low as . Yes, you read that right. Our Santo Tomas packages are the easiest way to make your budget stretch further. Bundle your preferred hotels, flights and car rentals and discover this wonderful destination.
How do I get a cheap travel package to Santo Tomas?
Imagine all the thrilling things you could do in Santo Tomas with extra cash in your wallet. Watch your savings stack up when you bundle your hotel and airfare bookings into a Santo Tomas holiday package. You have plenty of choice when it comes to booking with Expedia too. In fact, you can take your pick of over 550 air carriers and 1null000null000 properties around the world. Whether you're holidaying with the entire family or adventuring alone, planning a trip to Santo Tomas is better with a package.
Where should I stay in Santo Tomas?
With interesting attractions like Mexico City Arena and Hospital Juárez de México in this neighbourhood, look for a hotel located near either one. Planetario Luis Enrique Erro is another Santo Tomas hot spot that travellers flock to.
How far in advance should I book my Santo Tomas holiday?
It's tricky picking the perfect time for airfares, but we normally say the earlier, the better. Many international flights on Expedia become available to compare up to a year in advance. If you can't book early, don't worry. Budget prices occasionally appear just weeks before departure dates.
What does an Expedia Santo Tomas travel package include?
That depends on what type of getaway you want to have. Santo Tomas travel deals can include hotels, flights and car rentals. You can mix and match to create the travel package that suits your needs. You can also add on activities and experiences after you've booked to score even bigger discounts.
What should I know before booking a Santo Tomas travel package?
You'll save plenty with an Expedia travel package. Bundle your airfares, rental cars and hotels and unlock fantastic discounts. Hotels aren't your only option, though. Book with us and take your pick of beachside condos, chalets in the middle of mountains and even ranches and treehouses!
Can I choose my airline with a Santo Tomas Expedia holiday package?
Yes, definitely. Expedia has more than 550 partner airlines to select from around the world. With such a big range of choice, finding the perfect carrier to bring you to Santo Tomas won't be hard.
If I'm not able to travel, can I cancel my Santo Tomas holiday package?
It is possible to cancel your Santo Tomas booking if your plans have been upended. Whether you'll incur a fee or not depends on your airline, hotel or car rental company. You may be able to change or cancel your booking for free if you booked in the last 24 hours. Visit our Customer Service Portal to find out more.

Popular places to visit

Basilica of Our Lady of Guadalupe showing a church or cathedral, religious elements and a square or plaza

Basilica of Our Lady of Guadalupe

You can learn more about the history of Mexico City when you visit a top site such as Basilica of Our Lady of Guadalupe. Experience the fascinating museums and acclaimed art galleries in this culturally rich area.

Basilica of Our Lady of Guadalupe
The Angel of Independence Monument featuring a monument, heritage elements and central business district

Angel of Independence Monument

You can learn more about the history of Mexico City when you visit a top site such as Angel of Independence Monument. Visit the shops and stunning cathedral in this vibrant area.

Angel of Independence Monument
Palacio de Bellas Artes showing night scenes, heritage architecture and a square or plaza

Palacio de Bellas Artes

Palacio de Bellas Artes is a popular museum in Mexico City with a rich history. Experience the fascinating museums and acclaimed art galleries in this vibrant area.

Palacio de Bellas Artes