Search Hotels in Santuario, Phoenix

Start date: Check-in selected.
To Date
End date: Check-out
  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Santuario hotels

The Scott Resort & Spa

The Scott Resort & Spa
4.5 star property
22.7 km from Santuario
8.8 out of 10, Excellent, (1000)
"Great hotel and service!!"
United States
Kenneth
The price is 5.766.489 ₫
8.372.582 ₫ total
includes taxes & fees
28 Dec - 29 Dec
The Scott Resort & Spa

Hilton Vacation Club Scottsdale Villa Mirage

Hilton Vacation Club Scottsdale Villa Mirage
3.5 star property
7.2 km from Santuario
8.6 out of 10, Excellent, (1010)
"Staff was amazing, room was well equipped and amenities were great. Location was perfect!"
United States
Jennifer
The price is 2.569.379 ₫
3.709.035 ₫ total
includes taxes & fees
4 Jan - 5 Jan 2026
Hilton Vacation Club Scottsdale Villa Mirage

Hilton Garden Inn Scottsdale North/Perimeter Center

Hilton Garden Inn Scottsdale North/Perimeter Center
3.0 star property
7.8 km from Santuario
9.0 out of 10, Wonderful, (1000)
"Clean room, wonderful staff, great breakfast!"
United States
Michelle
The price is 2.569.379 ₫
2.928.323 ₫ total
includes taxes & fees
24 Dec - 25 Dec
Hilton Garden Inn Scottsdale North/Perimeter Center

Hilton Scottsdale Resort & Villas

Hilton Scottsdale Resort & Villas
4.0 star property
20.2 km from Santuario
8.2 out of 10, Very good, (1001)
"Great resort!"
United States
marco
The price is 3.756.907 ₫
5.182.531 ₫ total
includes taxes & fees
25 Dec - 26 Dec
Hilton Scottsdale Resort & Villas

Omni Scottsdale Resort & Spa at Montelucia

Omni Scottsdale Resort & Spa at Montelucia
4.0 star property
20.7 km from Santuario
9.4 out of 10, Exceptional, (1000)
"Had a great stay."
United States
Monika
The price is 7.587.501 ₫
9.927.550 ₫ total
includes taxes & fees
19 Dec - 20 Dec
Omni Scottsdale Resort & Spa at Montelucia

Sonesta Suites Scottsdale Gainey Ranch

Sonesta Suites Scottsdale Gainey Ranch
3.5 star property
16.5 km from Santuario
9.0 out of 10, Wonderful, (1000)
"Great location Very nice room Great breakfast and happy hour"
United States
Michael
The price is 3.344.037 ₫
4.711.984 ₫ total
includes taxes & fees
21 Dec - 22 Dec
Sonesta Suites Scottsdale Gainey Ranch

Inn at Eagle Mountain

Inn at Eagle Mountain
3.5 star property
21.3 km from Santuario
8.8 out of 10, Excellent, (1000)
"Very nice and well run. I will definitely stay here again."
United States
Mark
The price is 5.138.212 ₫
5.866.222 ₫ total
includes taxes & fees
17 Jan - 18 Jan 2026
Inn at Eagle Mountain

Canopy by Hilton Scottsdale Old Town

Canopy by Hilton Scottsdale Old Town
4.0 star property
Arts District, 24.4 km from Santuario
9.6 out of 10, Exceptional, (1003)
"Excellent location with wonderful staff. The roof top patio was my favourite spot in Arizona!"
Canada
Jacqueline
The price is 4.944.435 ₫
5.635.173 ₫ total
includes taxes & fees
23 Dec - 24 Dec
Canopy by Hilton Scottsdale Old Town

Hotel Valley Ho

Hotel Valley Ho
4.5 star property
Arts District, 24.4 km from Santuario
9.6 out of 10, Exceptional, (2147)
"Wonderful resort "
United States
Tim
The price is 6.478.743 ₫
7.383.739 ₫ total
includes taxes & fees
21 Dec - 22 Dec
Hotel Valley Ho

Hilton Vacation Club Rancho Manana Phoenix/Cave Creek

Hilton Vacation Club Rancho Manana Phoenix/Cave Creek
3.5 star property
13.7 km from Santuario
9.6 out of 10, Exceptional, (1005)
"Great location. Spacious casitas."
United States
KITTY
The price is 4.512.607 ₫
5.698.185 ₫ total
includes taxes & fees
5 Jan - 6 Jan 2026
Hilton Vacation Club Rancho Manana Phoenix/Cave Creek

Great Wolf Lodge Arizona

Great Wolf Lodge Arizona
4.0 star property
19 km from Santuario
9.0 out of 10, Wonderful, (904)
"Love the scavenger hunt and water playground "
United States
Shantel
The price is 4.713.249 ₫
5.515.444 ₫ total
includes taxes & fees
4 Jan - 5 Jan 2026
Great Wolf Lodge Arizona

The Hotel Serene Glendale Peoria, Surestay Collection by BW

The Hotel Serene Glendale Peoria, Surestay Collection by BW
2.5 star property
29.5 km from Santuario
7.8 out of 10, Good, (988)
"Great "
United States
Elizabeth
The price is 2.251.037 ₫
2.592.519 ₫ total
includes taxes & fees
28 Dec - 29 Dec
The Hotel Serene Glendale Peoria, Surestay Collection by BW

Holiday Inn Club Vacations Scottsdale Resort by IHG

Holiday Inn Club Vacations Scottsdale Resort by IHG
4.0 star property
7.2 km from Santuario
9.0 out of 10, Wonderful, (1001)
"Really comfortable, clean, staff service was great "
United States
Crysna
The price is 4.290.505 ₫
5.940.233 ₫ total
includes taxes & fees
19 Dec - 20 Dec
Holiday Inn Club Vacations Scottsdale Resort by IHG

Scottsdale Plaza Resort & Villas (soon to be Kimpton)

Scottsdale Plaza Resort & Villas (soon to be Kimpton)
4.0 star property
19 km from Santuario
8.8 out of 10, Excellent, (2165)
"Beautiful place to stay! "
United States
Jaycee
The price is 3.852.225 ₫
5.497.062 ₫ total
includes taxes & fees
21 Dec - 22 Dec
Scottsdale Plaza Resort & Villas (soon to be Kimpton)

Papago Scottsdale by Reside, Trademark Collection by Wyndham

Papago Scottsdale by Reside, Trademark Collection by Wyndham
3.0 star property
27.5 km from Santuario
8.6 out of 10, Excellent, (263)
"Awesome place "
United States
Tyler
The price is 2.350.042 ₫
2.678.344 ₫ total
includes taxes & fees
21 Dec - 22 Dec
Papago Scottsdale by Reside, Trademark Collection by Wyndham

HYATT house Scottsdale/Old Town

HYATT house Scottsdale/Old Town
3.0 star property
Downtown Scottsdale, 23.9 km from Santuario
8.8 out of 10, Excellent, (1119)
"Easy check-in, friendly staff."
Canada
Jacob
The price is 3.344.037 ₫
3.811.199 ₫ total
includes taxes & fees
25 Dec - 26 Dec
HYATT house Scottsdale/Old Town

Aiden by Best Western Scottsdale North

Aiden by Best Western Scottsdale North
3.0 star property
14.6 km from Santuario
9.0 out of 10, Wonderful, (1010)
"We stay there every time we go In Scottsdale."
United States
Andre
The price is 2.204.431 ₫
2.512.390 ₫ total
includes taxes & fees
28 Dec - 29 Dec
Aiden by Best Western Scottsdale North

Wekopa Casino Resort

Wekopa Casino Resort
4.0 star property
26.5 km from Santuario
9.2 out of 10, Wonderful, (1001)
"It was an amazing stay! "
United States
Whitney
Wekopa Casino Resort

Rise Uptown Hotel

Rise Uptown Hotel
4.0 star property
26.8 km from Santuario
9.2 out of 10, Wonderful, (1117)
"Great staff, great rooms."
United States
Robert
The price is 3.030.961 ₫
4.290.372 ₫ total
includes taxes & fees
21 Dec - 22 Dec
Rise Uptown Hotel

Hyatt Place Scottsdale/Old Town

Hyatt Place Scottsdale/Old Town
3.0 star property
Brown and Stetson Business, 23.9 km from Santuario
8.6 out of 10, Excellent, (1353)
"Rooms were spotless, staff was so friendly. Great location."
United States
Rebecca
The price is 2.896.410 ₫
3.301.038 ₫ total
includes taxes & fees
25 Dec - 26 Dec
Hyatt Place Scottsdale/Old Town
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Santuario

Find the best Santuario areas for the activities you enjoy most.

Downtown Phoenix

Known for its ample dining options and great live music, there's plenty to explore in Downtown Phoenix. You can visit top attractions like Chase Field and Mortgage Matchup Center, and jump on the metro at 12th Street - Jefferson Station or 12th Street - Washington Station to see more of the city.

Old Town

Gourmet restaurants interesting history and top sights from Western Spirit: Scottsdale's Museum of the West to Fiesta Bowl Museum – discover Old Town, a destination also famous for its shopping.

Camelback East

You might take some time to check out the abundant dining options in Camelback East. Spend some time visiting top spots like Biltmore Fashion Park, and catch the metro at 44th Street - Washington Station or 50th Street Station to see more of the area.

East Mesa

While you're in East Mesa, take in top sights like Salt River Tubing and jump on the metro at Superstition Springs Transit Center to see more of the city.

Central Scottsdale

If you're spending some time in Central Scottsdale, Scottsdale Ranch Park and Starfire Golf Club at Scottsdale Country Club are top sights worth seeing.

Top Santuario Hotel Reviews

Frequently asked questions

What is Santuario like?
You'll be sure to have fun exploring Scottsdale's Santuario neighbourhood.
If I need to cancel my hotel reservation in Santuario, will I receive a refund?
Yes, the majority of room reservations are fully refundable as long as you cancel prior to the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of check in. If your reservation is non-refundable, it may still be possible to cancel it and get a refund within a 24-hour period of your booking. Enter dates in and click on "Search", then use the "fully refundable" filter to review top deals in Santuario.
What is there to do around this Scottsdale neighbourhood?
Places you might want to visit in the area around Santuario include Arizona Powerchutes and Grayhawk Golf Club. Make a stop at Desert Ridge Marketplace and Musical Instrument Museum while you're sightseeing around the area.