The Best Hotels in Santuario, Phoenix - 2026 Updated Prices

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Our top choices for Santuario hotels

An outdoor seating area with fire pit, red Adirondack chairs, and a covered patio with string lights.

1. Home2 Suites by Hilton Scottsdale North

5.1 km from Santuario

Greta

4.442.161 ₫ total

includes taxes & fees

25 Oct - 26 Oct

An outdoor seating area with sofas, tables, and umbrellas, featuring a fire feature in the center.

2. Hyatt Place North Scottsdale

6.7 km from Santuario

Ana

3.838.413 ₫ total

includes taxes & fees

25 Oct - 26 Oct

A modern hotel entrance with a covered walkway, large windows, and a landscaped area with flowers.

3. Hilton Garden Inn North Phoenix Scottsdale

6.9 km from Santuario

Frances

4.084.377 ₫ total

includes taxes & fees

4 Oct - 5 Oct

A modern outdoor lounge area with sofas, chairs, and a glass-top coffee table with a fire feature.

4. Hyatt House North Scottsdale

6.7 km from Santuario

Slyqavious

3.996.348 ₫ total

includes taxes & fees

21 Oct - 22 Oct

A modern hotel with a flat roof, multiple floors, and a sign indicating 'Springhill Suites'.

5. SpringHill Suites Scottsdale North

7.9 km from Santuario

Charlene

4.220.940 ₫ total

includes taxes & fees

1 Nov - 2 Nov

A spacious lobby with stone walls, comfortable seating, and a large window offering a mountain view.

6. Hilton North Scottsdale At Cavasson

6.3 km from Santuario

Marcos

8.147.184 ₫ total

includes taxes & fees

9 Oct - 10 Oct

An outdoor patio with a fire pit, string lights, and outdoor furniture.

7. Hilton Vacation Club Scottsdale Links Resort

8.5 km from Santuario

Lindsay

5.093.761 ₫ total

includes taxes & fees

21 Oct - 22 Oct

A spacious lobby with a modern staircase, a comfortable seating area, and a large window providing natural light.

8. Sleep Inn North Scottsdale near Mayo Clinic

Paradise Valley Village, 8.4 km from Santuario

Andrew

3.721.421 ₫ total

includes taxes & fees

1 Nov - 2 Nov

A Courtyard Marriott hotel with a modern design, featuring multiple floors, a covered entrance, and well-lit surroundings.

9. Courtyard by Marriott Phoenix North/Happy Valley

16.6 km from Santuario

Jose

3.584.787 ₫ total

includes taxes & fees

25 Oct - 26 Oct

A spacious indoor area with multiple seating options including tables and chairs, a bar area with stools, and large windows providing natural light.

10. Best Western Plus Executive Residency Phoenix North Happy Valley

16.8 km from Santuario

Raul

3.234.242 ₫ total

includes taxes & fees

18 Oct - 19 Oct

An outdoor patio area with wicker furniture, a stone pillar, and a fire pit.

11. Hilton Garden Inn Scottsdale North/Perimeter Center

7.8 km from Santuario

Emily

4.347.239 ₫ total

includes taxes & fees

1 Nov - 2 Nov

A spacious lobby with a high ceiling, a central seating area with sofas and chairs, and a view into the dining area.

12. Drury Inn & Suites Phoenix Happy Valley

17.4 km from Santuario

Karen

3.494.594 ₫ total

includes taxes & fees

19 Oct - 20 Oct

A Hampton Inn hotel with a brick facade, multiple windows, and a landscaped entrance area with desert plants.

13. Hampton Inn by Hilton Carefree

12.5 km from Santuario

James

4.294.253 ₫ total

includes taxes & fees

13 Oct - 14 Oct

A spacious lobby with high ceilings, modern lighting, and a large mural of a desert landscape.

14. Hampton Inn & Suites Phoenix North/Happy Valley

17.7 km from Santuario

Marilyn

3.831.903 ₫ total

includes taxes & fees

31 Oct - 1 Nov

An outdoor patio area with a pool, seating, and palm trees.

15. AC Hotel by Marriott Phoenix North Norterra

17.1 km from Santuario

Zachary

4.199.739 ₫ total

includes taxes & fees

18 Oct - 19 Oct

A hotel lobby with a reception desk, seating area, and a large wall mural.

16. La Quinta Inn & Suites by Wyndham Phoenix Scottsdale

Central Scottsdale, 14.7 km from Santuario

Robert

2.492.413 ₫ total

includes taxes & fees

25 Oct - 26 Oct

A pool area with a waterfall feature, lounge chairs, and a clear sky.

17. Hilton Vacation Club Scottsdale Villa Mirage

7.2 km from Santuario

Wendy L

4.773.293 ₫ total

includes taxes & fees

4 Oct - 5 Oct

An outdoor patio with wicker furniture, a fire pit, and string lights.

18. Home2 Suites By Hilton Phoenix North Happy Valley

16.8 km from Santuario

Joseph

4.071.965 ₫ total

includes taxes & fees

1 Nov - 2 Nov

A Courtyard by Marriott hotel with a landscaped entrance featuring a small waterfall and rock formations.

19. Courtyard by Marriott Scottsdale North

8.1 km from Santuario

Jennifer

5.524.271 ₫ total

includes taxes & fees

16 Oct - 17 Oct

A spacious lobby with a large seating area, a reception desk, and artwork on the walls.

20. Best Western Plus Scottsdale Thunderbird Suites

Thunderbird Industrial Airpark, 10.1 km from Santuario

Susan

3.857.960 ₫ total

includes taxes & fees

3 Nov - 4 Nov

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Where to stay in Santuario

Find the best Santuario areas for the activities you enjoy most.

A cityscape with prominent buildings including a Chase bank and The Arizona Republic building.

Downtown Phoenix

Known for its ample dining options and great live music, there's plenty to explore in Downtown Phoenix. You can visit top attractions like Chase Field and Mortgage Matchup Center, and jump on the metro at 12th Street - Jefferson Station or 12th Street - Washington Station to see more of the city.

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A fountain with three horses, surrounded by red flowers and storefronts.

Old Town

Gourmet restaurants interesting history and top sights from Scottsdale Waterfront to Western Spirit: Scottsdale's Museum of the West – discover Old Town, a destination also famous for its shopping.

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A rocky hill with palm trees and a body of water.

Camelback East

You might take some time to check out the abundant dining options in Camelback East. Spend some time visiting top spots like Biltmore Fashion Park, and catch the metro at 44th Street - Washington Station or 50th Street Station to see more of the area.

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A hiker on a rocky trail with mountains in the background.

Rio Verde Foothills

If you're looking for some top things to see and do in Rio Verde Foothills and surrounding area, you can visit Golf Club Scottsdale and Tom's Thumb Trail.

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A mountainous landscape with a city in the valley below.

North Phoenix

While you're in North Phoenix, take in top sights like Reach 11 Sports Complex and jump on the metro at 19th Avenue/ Dunlap Station to see more of the city.

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Top Santuario Hotel Reviews

Hotel Valley Ho

10/10 Excellent

"Clean room amazing staff would definitely stay here again"

Kimpton Miralina Resort & Villas by IHG

10/10 Excellent

"My friend and I stayed here and had a lovely time. Although there was a slight delay in getting our room the staff was accommodating and ended up upgrading us. The restaurant had great breakfast options and the cafe was yummy too. Any staff we interacted with was great and the site itself was beautiful."

Hyatt Place North Scottsdale

8/10 Good

"The property was very nice, very clean, great breakfast with different options daily, the ladies working at the breakfast area were very accommodating and helpful, rooms were nice and clean. Stayed 4 nights, and the room was only serviced once on the 3rd day, but did get clean towels daily and trash was also taken out daily as well, didn't like that we had to pay for parking with a nightly charge, and at night time a/c seemed to be turned off and room would get a bit stuffy, we would turn down the temperature to 70 and it wouldn't turn back on until the morning around 8 or so which we would have to raise the temperature back up to 74 or it would get too cold."

Frequently asked questions

What is Santuario like?

You'll be sure to have fun exploring Scottsdale's Santuario neighbourhood.

If I need to cancel my hotel reservation in Santuario, will I receive a refund?

Yes, the majority of room reservations are fully refundable as long as you cancel prior to the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of check in. If your reservation is non-refundable, it may still be possible to cancel it and get a refund within a 24-hour period of your booking. Enter dates in and click on "Search", then use the "fully refundable" filter to review top deals in Santuario.

What is there to do around this Scottsdale neighbourhood?

A few places to visit in the area around Santuario include Arizona Powerchutes, Highlands Church and Grayhawk Golf Club. Make a stop at Desert Ridge Marketplace and Pinnacle Peak Park while you're sightseeing around the area.

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Our top choices for Santuario hotels

1. Home2 Suites by Hilton Scottsdale North

2. Hyatt Place North Scottsdale

3. Hilton Garden Inn North Phoenix Scottsdale

4. Hyatt House North Scottsdale

5. SpringHill Suites Scottsdale North

6. Hilton North Scottsdale At Cavasson

7. Hilton Vacation Club Scottsdale Links Resort

8. Sleep Inn North Scottsdale near Mayo Clinic

9. Courtyard by Marriott Phoenix North/Happy Valley

10. Best Western Plus Executive Residency Phoenix North Happy Valley

11. Hilton Garden Inn Scottsdale North/Perimeter Center

12. Drury Inn & Suites Phoenix Happy Valley

13. Hampton Inn by Hilton Carefree

14. Hampton Inn & Suites Phoenix North/Happy Valley

15. AC Hotel by Marriott Phoenix North Norterra

16. La Quinta Inn & Suites by Wyndham Phoenix Scottsdale

17. Hilton Vacation Club Scottsdale Villa Mirage

18. Home2 Suites By Hilton Phoenix North Happy Valley

19. Courtyard by Marriott Scottsdale North

20. Best Western Plus Scottsdale Thunderbird Suites

Where to stay in Santuario

Downtown Phoenix

Old Town

Camelback East

Rio Verde Foothills

North Phoenix

Top Santuario Hotel Reviews

Hotel Valley Ho

Frequently asked questions

Explore a world of travel with Expedia