
Seneca Holidays
Book a Hotel + Flight or Car together to unlock savings
Photo by Deidree DeHart
Where to stay in Seneca
Find the best Seneca areas and neighborhoods for the activities you enjoy most. Learn more about Seneca

Pine Ridge Point
If you're looking for some top things to see and do in Pine Ridge Point and surrounding area, you can visit Lake Keowee and Keowee Key Golf Course.
Top hotels in Seneca

Lakeside Lodge Clemson
13500 Clemson Blvd, Seneca, SC
Fully refundableReserve now, pay when you stay
The price is 2.874.657 ₫ per night from 23 Aug to 24 Aug
2.874.657 ₫
3.604.135 ₫ total
23 Aug - 24 Aug
includes taxes & fees
8.8/10 Excellent! (994 reviews)
"Stayed in one BR unit with full kitchen which was great! Blender worked perfectly for our daiquiris. It was a hot & sunny weekend. Pool was clean & plenty of chairs. Lobby & outdoor sitting areas nice & comfy during this busy weekend too. Would definitely recommend this resort. Can walk to shopping ..."
Reviewed on 18 Aug 2025

Quality Inn Seneca Clemson Area US-123
226 Hi Tech Rd, Seneca, SC
Fully refundableReserve now, pay when you stay
The price is 2.112.477 ₫ per night from 7 Sept to 8 Sept
2.112.477 ₫
2.584.897 ₫ total
7 Sept - 8 Sept
includes taxes & fees
7.8/10 Good! (632 reviews)
Nice hotel!
"Nice clean, comfortable stay with a great breakfast."
Reviewed on 19 Aug 2025

Hampton Inn & Suites Seneca-Clemson Area
1011 East North 1st Street, Seneca, SC
Fully refundableReserve now, pay when you stay
The price is 3.197.990 ₫ per night from 24 Aug to 25 Aug
3.197.990 ₫
3.517.787 ₫ total
24 Aug - 25 Aug
includes taxes & fees
9.2/10 Wonderful! (628 reviews)
"The staff were very friendly and helpful. The room was clean and the breakfast was great!"
Reviewed on 19 Aug 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.