The Best Hotels in Serin, Lyon - 2026 Updated Prices

A cityscape at dusk with a prominent cathedral and a bridge over a river.

Change your mind
Book hotels with free cancellation
Treat yourself
Sign in to save 10% or more on thousands of hotels
Sign in
Be picky
Search almost a million properties worldwide

Check prices for these dates

Tonight

Tomorrow

Next weekend

In two weeks

Our top choices for Serin hotels

An aerial view of a circular swimming pool with a central fountain, surrounded by lush greenery.

1. Hôtel Lyon Métropole & Spa

Serin

Gavin

3.468.978 ₫ total

includes taxes & fees

25 Oct - 26 Oct

A courtyard with a central fountain, surrounded by a building with arched windows and a tiled floor.

2. Fourvière Hôtel Lyon

Fourvière, 2.3 km from Serin

marc

3.795.363 ₫ total

includes taxes & fees

15 Nov - 16 Nov

A multi-story building with a rooftop pool, surrounded by a landscaped area with trees and a fence.

3. The Ruck Hotel

Gerland, 6.1 km from Serin

haobo

3.033.552 ₫ total

includes taxes & fees

18 Oct - 19 Oct

A high-rise hotel room with large windows, a round dining table, and modern chairs.

4. Villa Florentine, A Beauvallon Hotel & Spa

2 km from Serin

Harry

9.160.399 ₫ total

includes taxes & fees

1 Nov - 2 Nov

A balcony with a view of a river and buildings.

5. Le Phenix Hotel

Old Lyon, 1.7 km from Serin

Elizabeth

4.134.805 ₫ total

includes taxes & fees

1 Nov - 2 Nov

A modern restaurant with high ceilings, hanging plants, and a bar area.

6. The People Lyon

1.3 km from Serin

Simone

2.207.560 ₫ total

includes taxes & fees

8 Nov - 9 Nov

A modern hotel room with a large bed, wooden ceiling beams, a desk with a chair, and a dining area.

7. Académie Hôtel Lyon

Old Lyon, 1.8 km from Serin

Rhonda

4.113.917 ₫ total

includes taxes & fees

15 Nov - 16 Nov

A spacious interior with multiple dining areas, red curtains, and a central seating area with a red sofa.

8. Cour des Loges Lyon, A Radisson Collection Hotel

Old Lyon, 2 km from Serin

Sharon

6.593.890 ₫ total

includes taxes & fees

25 Oct - 26 Oct

A narrow street lined with multi-story buildings, some with balconies and shutters.

9. Hotel Saint Vincent

1.5 km from Serin

Gail

2.806.631 ₫ total

includes taxes & fees

25 Oct - 26 Oct

An indoor swimming pool with stone walls and a wooden structure in the background.

10. Grand Hotel Des Terreaux

Terreaux - Bat d'argent, 1.9 km from Serin

Peter

3.664.810 ₫ total

includes taxes & fees

18 Oct - 19 Oct

A modern lobby with stone walls, large windows, a flat-screen TV, and a cactus plant.

11. Residence Belambra Villemanzy

1.7 km from Serin

Carey

2.171.266 ₫ total

includes taxes & fees

8 Nov - 9 Nov

A balcony with a view of a historic cityscape, including a church and a tower.

12. Collège Hôtel

Old Lyon, 1.8 km from Serin

Emely

2.914.297 ₫ total

includes taxes & fees

1 Nov - 2 Nov

An indoor swimming pool with clear views of the outside through large windows.

13. Villa Maïa

Fourvière, 2.3 km from Serin

Yasuko

12.325.127 ₫ total

includes taxes & fees

1 Nov - 2 Nov

A hotel with a modern facade, large windows, and a prominent sign.

14. Hôtel Le Roosevelt

2.8 km from Serin

Thomas

3.300.824 ₫ total

includes taxes & fees

25 Oct - 26 Oct

A modern hotel room with a large bed, a desk with a computer, a red chair, and a shower area.

15. Maison Nô

Terreaux - Bat d'argent, 2.1 km from Serin

Isaac

2.534.730 ₫ total

includes taxes & fees

8 Nov - 9 Nov

A hotel with a courtyard, benches, and a fountain.

16. Carlton Hotel Lyon - MGallery Collection

Les Cordeliers, 2.6 km from Serin

Ingrid

5.237.846 ₫ total

includes taxes & fees

15 Nov - 16 Nov

A restaurant with multiple round tables and chairs, large windows offering a view of greenery and buildings, and hanging spherical light fixtures.

17. Novotel Lyon Centre Confluence Bord de Saone

La Confluence, 4.3 km from Serin

Charles

3.151.295 ₫ total

includes taxes & fees

8 Nov - 9 Nov

A modern dining area with a long wooden table, black bar stools, and pendant lighting.

18. OKKO Hotels Lyon Centre

2.6 km from Serin

Ngoc Hong An

3.241.232 ₫ total

includes taxes & fees

25 Oct - 26 Oct

An outdoor café with tables and chairs, surrounded by greenery and architectural arches.

19. Intercontinental Lyon Hotel Dieu by IHG

Bellecour - Hôtel Dieu, 2.9 km from Serin

Hey Eun

6.641.452 ₫ total

includes taxes & fees

15 Nov - 16 Nov

A balcony table with breakfast items, a view of a bridge, and greenery.

20. Boscolo Lyon Hôtel & Spa

Les Cordeliers, 2.7 km from Serin

Amar

6.883.198 ₫ total

includes taxes & fees

29 Oct - 30 Oct

View all properties

Where to stay in Serin

Find the best Serin areas for the activities you enjoy most.

A statue of a figure holding a staff, overlooking a city with red-roofed buildings and a river.

Lyon City Centre

Gourmet restaurants interesting history and top sights from Bellecour Square to Hôtel-Dieu – discover Lyon City Centre, a destination also famous for its shopping.

See properties

A statue of an angel overlooking a densely packed city with red-roofed buildings and a river.

Old Lyon

If you're spending time in Old Lyon, you might enjoy attractions like Lyon Cathedral and Palais de Justice de Lyon. You might also enjoy the neighbourhood's ample dining options before hopping on the metro at Vieux Lyon Station to see more of the city.

See properties

A Ferris wheel with lights and the text "Lyon" and "EUROPA-RAO" at its base.

Bellecour - Hôtel Dieu

While you're in Bellecour - Hôtel Dieu, take in top sights like Bellecour Square and jump on the metro at Bellecour Station to see more of the city.

See properties

A cityscape with modern skyscrapers and historic buildings under a dramatic sky.

3rd Arrondissement

Noted for its shopping and river views, there's plenty to explore in 3rd Arrondissement. Top attractions like Part Dieu Mall and Halles de Lyon - Paul Bocuse are major draws, and you can hop on the metro at Dauphine - Lacassagne Tram Stop or Archives Départementales Tram Stop to see more of the city.

See properties

A street with a cafe named "Grand Cafe Des Negotiants" and a clock.

Les Cordeliers

Take time in Les Cordeliers to visit attractions like Museum of Fine Arts of Lyon and Place des Jacobins. You might also appreciate the abundant dining options, and you can hop on the metro at Cordeliers Bourse Station to see more of the city.

See properties

Top Serin Hotel Reviews

Campanile PRIME - Lyon Centre Gare Part Dieu

10/10 Excellent

"The hotel is a 2 minute walk from the Gare Part Dieu, so very convenient for the train as well as local busses, metro and trams. It is a 45 minute walk from the old town if you don’t use public transport. The hotel was excellent clean and exactly as it looked on the internet pictures, and the breakfast was good value,, though there are also lots of Patisserie’s near by.Would definitely recommend."

Kyriad Prestige Lyon Est - Saint Priest Eurexpo Hotel and Spa

8/10 Good

"Das Zimmer war sehr schön und sauber, aber sehr ringhörig. Unser Zimmer lag im 1. Stock, also genau über der Lobby. In der ersten Nacht habe ich kaum geschlafen, da man immer die Geräusche/Stimmen aus dem Gang, der Lobby und dem Restaurant gehört hat. Das Spa ist klein aber fein. Jedoch sieht man auch, dass es schon etwas älter ist. Auch er Whirpool könnte mal ersetzt werden, der Boden war ganz braun und eine Abdeckung hing nur noch so halb dran. Aber für den Preis kann man nichts sagen. Aber das Superior Zimmer mit Spa Eintritt lohn sich nicht. Es ist günstiger ein normales Zimmer zu buchen und den Spa Eintritt extra zu bezahlen."

Mercure Lyon Centre Château Perrache

10/10 Excellent

"We chose the hotel due to close proximity to the Parrache station , it’s good reviews and price. It is located in a beautiful old chateau style building, The interior was an architectural gem. The staff were very friendly and helpful. We would highly recommend."

Radisson Blu Hotel Lyon

10/10 Excellent

"I enjoyed the breakfast and the room was comfortable but the most important thing to me was the location. The hotel is perfectly situated for access to the main railway station. The tram stopped right outside and took you to the metro line D which went to the old town. Very convenient. There are plenty of good restaurants nearby and Westfield is right outside the door."

Frequently asked questions

What is Serin like?

You'll be sure to have fun exploring Lyon's Serin neighbourhood. Consider a visit to Historic Site of Lyon as part of your Serin travel plans.

If I need to cancel my hotel reservation in Serin, will I receive a refund?

Yes! Most hotel bookings are fully refundable provided that you cancel before the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of check in. If you have a non-refundable reservation, you might be able to cancel it and be given a refund within 24 hours of your booking. Add dates, click "Search", then you can use the "fully refundable" filter to review the best deals in Serin.

What is there to do in this Lyon neighbourhood?

Historic Site of Lyon is an attraction you might want to check out while you're in Serin. While you're out sightseeing, Mur des Canuts and Le Jardin Des Chartreux are a couple of additional sights to visit in Lyon.

Explore a world of travel with Expedia

Car hire Relevant

Book Hotels in Serin on Expedia.fr

Search Hotels in Serin, Lyon

Change your mind

Treat yourself

Be picky

Check prices for these dates

Filter by

Star rating

Guest rating

Our top choices for Serin hotels

1. Hôtel Lyon Métropole & Spa

2. Fourvière Hôtel Lyon

3. The Ruck Hotel

4. Villa Florentine, A Beauvallon Hotel & Spa

5. Le Phenix Hotel

6. The People Lyon

7. Académie Hôtel Lyon

8. Cour des Loges Lyon, A Radisson Collection Hotel

9. Hotel Saint Vincent

10. Grand Hotel Des Terreaux

11. Residence Belambra Villemanzy

12. Collège Hôtel

13. Villa Maïa

14. Hôtel Le Roosevelt

15. Maison Nô

16. Carlton Hotel Lyon - MGallery Collection

17. Novotel Lyon Centre Confluence Bord de Saone

18. OKKO Hotels Lyon Centre

19. Intercontinental Lyon Hotel Dieu by IHG

20. Boscolo Lyon Hôtel & Spa

Where to stay in Serin

Lyon City Centre

Old Lyon

Bellecour - Hôtel Dieu

3rd Arrondissement

Les Cordeliers

Top Serin Hotel Reviews

Campanile PRIME - Lyon Centre Gare Part Dieu

Frequently asked questions

Explore a world of travel with Expedia