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Our top choices for Serin hotels

Hotel Lyon Métropole

Hotel Lyon Métropole
4.0 star property
Serin
8.6 out of 10, Excellent, (1000)
"It is worth paying for spa/pool. It is amazing! Nice clean hotel and polite staff"
Norway
Anonymous traveller
The price is 3.619.859 ₫
4.158.408 ₫ total
includes taxes & fees
4 Jan - 5 Jan 2026
Hotel Lyon Métropole

Grand Hotel Des Terreaux

Grand Hotel Des Terreaux
4.0 star property
1.9 km from Serin
8.8 out of 10, Excellent, (1001)
"helpful staff, hotel location, amenities"
Canada
Rick
The price is 2.905.632 ₫
3.372.450 ₫ total
includes taxes & fees
24 Dec - 25 Dec
Grand Hotel Des Terreaux

Le Phenix Hotel

Le Phenix Hotel
4.0 star property
Old Lyon, 1.7 km from Serin
9.2 out of 10, Wonderful, (1001)
"Fantastic location with excellent rooms"
United States
Hudson
The price is 3.358.718 ₫
3.871.122 ₫ total
includes taxes & fees
24 Dec - 25 Dec
Le Phenix Hotel

Hotel Silky by HappyCulture

Hotel Silky by HappyCulture
4.0 star property
Les Cordeliers, 2.3 km from Serin
8.8 out of 10, Excellent, (969)
"Amazing location and hotel. Perfect for seeing the sites and coming back and feeling welcomed by the staff. Great breakfast too!"
Canada
Cameron
The price is 2.773.244 ₫
3.226.823 ₫ total
includes taxes & fees
18 Jan - 19 Jan 2026
Hotel Silky by HappyCulture

Fourvière Hôtel Lyon

Fourvière Hôtel Lyon
4.0 star property
Fourvière, 2.3 km from Serin
9.2 out of 10, Wonderful, (1000)
"This property was excellent "
United States
Ed
Fourvière Hôtel Lyon

OKKO Hotels Lyon Centre

OKKO Hotels Lyon Centre
4.0 star property
2.6 km from Serin
9.0 out of 10, Wonderful, (1000)
"Fantastic hotel, welcoming staff. "
Canada
Carol
The price is 2.898.997 ₫
3.365.460 ₫ total
includes taxes & fees
21 Dec - 22 Dec
OKKO Hotels Lyon Centre

Maison Nô

Maison Nô
4.0 star property
2.1 km from Serin
9.0 out of 10, Wonderful, (401)
"Spotless room, comforting decor, wonderful staff"
United Kingdom
Andrew
Maison Nô

Best Western Hotel Saint Antoine

Best Western Hotel Saint Antoine
3.0 star property
Les Cordeliers, 2.4 km from Serin
8.2 out of 10, Very good, (434)
"Really great location and helpful staff. Really cramped room, though one of the two the best showers we have had of 20 different hotel rooms on this trip. "
United States
Fred
The price is 1.905.942 ₫
2.211.981 ₫ total
includes taxes & fees
11 Jan - 12 Jan 2026
Best Western Hotel Saint Antoine

Hôtel Mercure Lyon Centre Plaza République

Hôtel Mercure Lyon Centre Plaza République
4.0 star property
Les Cordeliers, 2.7 km from Serin
8.4 out of 10, Very good, (686)
"Location excellent"
United States
DIDEM
The price is 2.838.147 ₫
3.298.525 ₫ total
includes taxes & fees
4 Jan - 5 Jan 2026
Hôtel Mercure Lyon Centre Plaza République

Hôtel Bayard Bellecour

Hôtel Bayard Bellecour
4.0 star property
Bellecour - Hôtel Dieu, 2.9 km from Serin
8.6 out of 10, Excellent, (420)
"Very good hotel in a central area, quiet room and very nice staff! "
United States
Sandrine
Hôtel Bayard Bellecour

Hôtel des Célestins

Hôtel des Célestins
3.0 star property
Bellecour - Hôtel Dieu, 2.6 km from Serin
9.0 out of 10, Wonderful, (394)
"This is the perfect location and a beautiful smaller hotel, highly recommend."
United States
Steven
The price is 2.722.821 ₫
3.110.347 ₫ total
includes taxes & fees
3 Jan - 4 Jan 2026
Hôtel des Célestins

Hôtel des Artistes

Hôtel des Artistes
3.0 star property
Bellecour - Hôtel Dieu, 2.5 km from Serin
9.0 out of 10, Wonderful, (1000)
"Great location, comfortable room, excellent value "
United States
Glen
The price is 2.828.606 ₫
3.226.912 ₫ total
includes taxes & fees
25 Dec - 26 Dec
Hôtel des Artistes

Hôtel Alexandra

Hôtel Alexandra
4.0 star property
2nd Arrondissement, 3.1 km from Serin
8.4 out of 10, Very good, (657)
"Fine place to stay "
United Kingdom
Michael
Hôtel Alexandra

Hotel Charlemagne By HappyCulture

Hotel Charlemagne By HappyCulture
4.0 star property
3.8 km from Serin
8.4 out of 10, Very good, (1001)
"The room was very clean, spacious and had so many great amenities."
United Kingdom
Ella
The price is 2.693.911 ₫
3.139.865 ₫ total
includes taxes & fees
11 Jan - 12 Jan 2026
Hotel Charlemagne By HappyCulture

Collège Hôtel

Collège Hôtel
4.0 star property
Old Lyon, 1.8 km from Serin
8.4 out of 10, Very good, (765)
"Loved it"
United States
Steven
Collège Hôtel

Le Royal Hotel Lyon - MGallery Collection

Le Royal Hotel Lyon - MGallery Collection
5.0 star property
Bellecour - Hôtel Dieu, 2.9 km from Serin
9.0 out of 10, Wonderful, (1000)
"Great staff and excellent location "
United States
Dana
The price is 5.333.102 ₫
6.110.884 ₫ total
includes taxes & fees
23 Dec - 24 Dec
Le Royal Hotel Lyon - MGallery Collection

Campanile Lyon Centre-Berges du Rhône

Campanile Lyon Centre-Berges du Rhône
3.0 star property
3rd Arrondissement, 3.2 km from Serin
7.8 out of 10, Good, (1000)
"Good stay for one night in Lyon. Good basic hotel. "
United Kingdom
Olivia
The price is 1.840.377 ₫
2.139.859 ₫ total
includes taxes & fees
11 Jan - 12 Jan 2026
Campanile Lyon Centre-Berges du Rhône

Radisson Blu Hotel Lyon

Radisson Blu Hotel Lyon
4.0 star property
Part Dieu - Bir Hakeim, 3.6 km from Serin
8.4 out of 10, Very good, (1003)
"It was great. The room was clean and comfortable. The staff were helpful and friendly"
United States
Glenn
The price is 3.423.512 ₫
3.942.426 ₫ total
includes taxes & fees
4 Jan - 5 Jan 2026
Radisson Blu Hotel Lyon

Mercure Lyon Centre Beaux Arts

Mercure Lyon Centre Beaux Arts
4.0 star property
Les Cordeliers, 2.5 km from Serin
9.0 out of 10, Wonderful, (1000)
"Relatively basic hotel in a great location with excellent staff."
United Kingdom
Ian
The price is 3.185.550 ₫
3.680.668 ₫ total
includes taxes & fees
11 Jan - 12 Jan 2026
Mercure Lyon Centre Beaux Arts

MiHotel

MiHotel
Bellecour - Hôtel Dieu, 2.6 km from Serin
8.2 out of 10, Very good, (543)
"This was the loveliest hotel that we stayed in on our European vacation, clean and modern. I would recommend MiHotel to anyone staying in the Lyon area"
Australia
Lachlan
The price is 3.300.069 ₫
3.811.547 ₫ total
includes taxes & fees
21 Dec - 22 Dec
MiHotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Serin

Find the best Serin areas for the activities you enjoy most.

Lyon City Centre

Gourmet restaurants interesting history and top sights from Bellecour Square to Place Carnot – discover Lyon City Centre, a destination also famous for its shopping.

Old Lyon

If you're spending time in Old Lyon, you might enjoy attractions like Lyon Cathedral and Palais de Justice de Lyon. You might also enjoy the neighbourhood's ample dining options before hopping on the metro at Vieux Lyon Station to see more of the city.

Bellecour - Hôtel Dieu

While you're in Bellecour - Hôtel Dieu, take in top sights like Bellecour Square and jump on the metro at Bellecour Station to see more of the city.

3rd Arrondissement

Noted for its shopping and river views, there's plenty to explore in 3rd Arrondissement. Top attractions like Part Dieu Mall and Halles de Lyon - Paul Bocuse are major draws, and you can hop on the metro at Dauphine - Lacassagne Tram Stop or Archives Départementales Tram Stop to see more of the city.

2nd Arrondissement

Travellers love 2nd Arrondissement for its popular shops, and you can see more of Lyon by jumping on the metro at Place des Archives or Sainte-Blandine Tram Stop. You might spend time checking out top sights like Place Carnot and Lyon Confluence Shopping Center.

Top Serin Hotel Reviews

Frequently asked questions

What is Serin like?
You'll be sure to have fun exploring Lyon's Serin neighbourhood. Consider a visit to Historic Site of Lyon as part of your Serin travel plans.
If I need to cancel my hotel reservation in Serin, will I receive a refund?
Yes! Most hotel bookings are fully refundable provided that you cancel before the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of check in. If you have a non-refundable reservation, you might be able to cancel it and be given a refund within 24 hours of your booking. Add dates, click "Search", then you can use the "fully refundable" filter to review the best deals in Serin.
What is there to do in this Lyon neighbourhood?
Historic Site of Lyon is an attraction you might want to check out while you're in Serin. While you're out sightseeing, Mur des Canuts and Le Jardin Des Chartreux are a couple of additional sights to visit in Lyon.