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Our top choices for Sistine Chapel hotels

Property entrance
San Pietro Boutique Rooms

San Pietro Boutique Rooms

San Pietro Boutique Rooms
0.6 km from Sistine Chapel
10.0 out of 10, Exceptional, (915)
"Great place to stay in Rome. Quiet and less crowded. "
United States
Tanya
San Pietro Boutique Rooms
Junior Suite, Terrace | Private spa tub
Le Boutique Hotel

Le Boutique Hotel

Le Boutique Hotel
4.0 star property
0.3 km from Sistine Chapel
9.4 out of 10, Exceptional, (119)
"We really enjoyed our stay at Le boutique hotel. We loved the food, and friendly staff, the room was clean every day, the area was very safe to walk everywhere, especially very close to the Vatican. We highly recommend it. "
United States
Patricia
The price is 4.320.209 ₫
5.214.437 ₫ total
includes taxes & fees
8 Jan - 9 Jan 2026
Le Boutique Hotel
Free daily full breakfast
My Bed Vatican Museum

My Bed Vatican Museum

My Bed Vatican Museum
0.5 km from Sistine Chapel
10.0 out of 10, Exceptional, (121)
"WORDS just aren’t enough to express the GRATITUDE I have for my stay at Ernesto and Paula’s Hotel. Pristine, Peaceful, Accommodating, SAFE, Generous and that’s only the beginning. Not to mention, Location was perfect for my visit. Definitely hope to visit Rome again, and there’s no doubt where I’ll be staying. "
United States
Jacqueline
The price is 8.294.463 ₫
9.555.364 ₫ total
includes taxes & fees
8 Jan - 9 Jan 2026
My Bed Vatican Museum
Free daily continental breakfast
B&B Roma Borgo 91

B&B Roma Borgo 91

B&B Roma Borgo 91
0.5 km from Sistine Chapel
9.8 out of 10, Exceptional, (63)
"Was very clean and wonderful. very much enjoyed our time there."
United States
Joseph
B&B Roma Borgo 91
Panoramic Studio Suite, Terrace | Minibar, in-room safe, individually decorated, individually furnished
Passpartout Boutique Palace

Passpartout Boutique Palace

Passpartout Boutique Palace
0.5 km from Sistine Chapel
9.8 out of 10, Exceptional, (246)
"Excellent location, great dining options nearby, modern boutique hotel."
Canada
Matthew
The price is 3.269.696 ₫
4.028.059 ₫ total
includes taxes & fees
13 Jan - 14 Jan 2026
Passpartout Boutique Palace
Property amenity
Residenza Paolo VI

Residenza Paolo VI

Residenza Paolo VI
0.3 km from Sistine Chapel
9.2 out of 10, Wonderful, (527)
"It was great stay all round"
Australia
Saad
Residenza Paolo VI
Classic Suite | Bathroom | Free toiletries, hair dryer, bathrobes, slippers
Vatican Style

Vatican Style

Vatican Style
0.4 km from Sistine Chapel
9.2 out of 10, Wonderful, (851)
"Would definitely stay again when looking for close to Vatican location. "
United States
Kevin
The price is 2.859.998 ₫
3.454.136 ₫ total
includes taxes & fees
13 Jan - 14 Jan 2026
Vatican Style
View from property
Rest Guesthouse

Rest Guesthouse

Rest Guesthouse
0.5 km from Sistine Chapel
9.6 out of 10, Exceptional, (172)
"We really enjoyed our stay. The staff were very friendly and helpful and the location is perfect for sightseeing. "
United Kingdom
Peter
Rest Guesthouse
Exterior detail
Eccelso Hotel

Eccelso Hotel

Eccelso Hotel
3.0 star property
0.6 km from Sistine Chapel
9.6 out of 10, Exceptional, (206)
"Great place, great service, great location! highly recommended"
Canada
Jensen
The price is 3.235.451 ₫
3.928.762 ₫ total
includes taxes & fees
22 Dec - 23 Dec
Eccelso Hotel
Classic Quadruple Room | Hypo-allergenic bedding, minibar, in-room safe, desk
Hotel Sant' Anna

Hotel Sant' Anna

Hotel Sant' Anna
3.0 star property
0.5 km from Sistine Chapel
9.6 out of 10, Exceptional, (323)
"Wonderful location, very helpful service and staff!"
United States
Stephen
Hotel Sant' Anna
Premium Quadruple Room, City View | Minibar, in-room safe, desk, soundproofing
Tmark Hotel Vaticano

Tmark Hotel Vaticano

Tmark Hotel Vaticano
4.0 star property
0.4 km from Sistine Chapel
9.0 out of 10, Wonderful, (785)
"Great hotel, excellent service and the best location if visiting the Vatican "
United States
Mario
Tmark Hotel Vaticano
Suite | Premium bedding, down duvets, in-room safe, desk
The Pope's Window

The Pope's Window

The Pope's Window
0.5 km from Sistine Chapel
9.4 out of 10, Exceptional, (411)
"The room was great except you can hear the pkumbing from the other rooms but nothing too bothersome it was very clean and very close to the St. Peters Basilica. A less than 5 min walk."
United States
Zuzell
The price is 2.459.362 ₫
3.075.065 ₫ total
includes taxes & fees
22 Dec - 23 Dec
The Pope's Window
Exterior
SUITES 51

SUITES 51

SUITES 51
0.5 km from Sistine Chapel
9.6 out of 10, Exceptional, (21)
"Location is excellent, beside the Vatican and a short walk to all the main attractions in Rome. The suites are newly renovated with comfortable beds. Perfect spot."
United States
Sandy
The price is 2.218.594 ₫
2.810.220 ₫ total
includes taxes & fees
7 Jan - 8 Jan 2026
SUITES 51
Sauna, hot tub, steam room
The Spring House Hotel Rome Vatican, Tapestry Collection Hilton

The Spring House Hotel Rome Vatican, Tapestry Collection Hilton

The Spring House Hotel Rome Vatican, Tapestry Collection Hilton
4.0 star property
0.5 km from Sistine Chapel
9.2 out of 10, Wonderful, (1001)
"The buffet breakfast and sauna were great!"
United States
Kelvin S
The price is 4.047.815 ₫
4.914.803 ₫ total
includes taxes & fees
22 Dec - 23 Dec
The Spring House Hotel Rome Vatican, Tapestry Collection Hilton
Classic Double Room | Hypo-allergenic bedding, minibar, soundproofing, iron/ironing board
Vatican Jubilee

Vatican Jubilee

Vatican Jubilee
0.6 km from Sistine Chapel
9.6 out of 10, Exceptional, (57)
"Great place!"
United States
Hugo
The price is 1.957.078 ₫
2.522.551 ₫ total
includes taxes & fees
6 Jan - 7 Jan 2026
Vatican Jubilee
Exterior
Starhotels Michelangelo

Starhotels Michelangelo

Starhotels Michelangelo
4.0 star property
0.5 km from Sistine Chapel
9.2 out of 10, Wonderful, (1002)
"Love this hotel "
United States
Tracy
The price is 5.042.261 ₫
6.008.694 ₫ total
includes taxes & fees
22 Dec - 23 Dec
Starhotels Michelangelo
Exterior
Velantia Vaticano - Guesthouse

Velantia Vaticano - Guesthouse

Velantia Vaticano - Guesthouse
0.6 km from Sistine Chapel
9.6 out of 10, Exceptional, (8)
"Great place to stay for a few days in Rome. Good location, great restaurant next door. Bed was super complicated. Would recommend for a couple or single person. "
Australia
Claudette
Velantia Vaticano - Guesthouse
Double Room, Balcony | View from room
Innsiderome

Innsiderome

Innsiderome
0.3 km from Sistine Chapel
8.8 out of 10, Excellent, (169)
"location, clean room"
United States
Rafael
Innsiderome
Reception
Borgo Pio Suites Inn

Borgo Pio Suites Inn

Borgo Pio Suites Inn
0.4 km from Sistine Chapel
9.2 out of 10, Wonderful, (375)
"A great location close to St Peter’s Square. Lots of eateries close by as well. Rooms were good and very clean. "
United Kingdom
Duncan
The price is 2.363.536 ₫
2.969.656 ₫ total
includes taxes & fees
22 Dec - 23 Dec
Borgo Pio Suites Inn
Classic Room | Frette Italian sheets, premium bedding, down duvets, Select Comfort beds
Borgo Vaticano Guest House

Borgo Vaticano Guest House

Borgo Vaticano Guest House
0.5 km from Sistine Chapel
9.2 out of 10, Wonderful, (107)
"Great location, clean room, friendly staff"
United States
Marietta
Borgo Vaticano Guest House
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Sistine Chapel Hotel Reviews

Hotels near other Sistine Chapel attractions

St Peters Basilica, Rome, Italy

St. Peter's Basilica

4.7/5 (14,967 reviews)
You can learn about the local history of Vatican City when you visit a top site such as St. Peter's Basilica. Stroll along the riverfront or visit the churches in this vibrant area.
See properties
View from the top of the Vatican looking towards Castel Sant'Angelo
Photo by Andrew Manwaring
Open Photo by Andrew Manwaring

Vatican Necropolis

You can browse the exhibits at Vatican Necropolis, a museum with a storied past, during your travels to Vatican City. Stroll along the riverfront in this vibrant area or seek out the local tours.
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Frequently asked questions

What's the area like around Sistine Chapel?
Sistine Chapel is located in a historic area of Vatican City known for its stunning river views and stunning cathedral. If you're looking for a convenient place to stay, take a look at the 1183 hotels and other accommodation options you'll find within a mile.
How many hotels will I find close to Sistine Chapel?
Expedia has 1183 hotels and other accommodation options within a mile from Sistine Chapel.
If I need to cancel the hotel reservation for my stay near Sistine Chapel, will I receive a refund?
Yes! You'll find that most room reservations are fully refundable if you cancel before the accommodation's cancellation deadline, which is usually within 24-48 hours of your scheduled arrival. If your reservation is non-refundable, it might still be possible to cancel it and receive a refund within a 24-hour period of your booking. Enter your dates, click on "Search", then you can use the "fully refundable" filter to get the top deals on offer near Sistine Chapel.
What can I see and do near Sistine Chapel?
Vatican Museums, Castel Sant'Angelo and Cloister of Bramante feature captivating exhibits. Explore landmarks like Piazza Navona, Pantheon and Spanish Steps. You can catch a show at Paul VI Audience Hall, Auditorium Conciliazione and Sistina Theater.
How can I get to Sistine Chapel?
With so many choices for transport, seeing all of the area near Sistine Chapel is easy. You can walk to nearby metro stations including Ottaviano - San Pietro - Musei Vaticani Station, Risorgimento/S. Pietro Tram Stop and Milizie-Angelico Tram Stop. To venture out into the surrounding area, ride one of the trains from Rome Valle Aurelia Station or Rome San Pietro Station.