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Our top choices for Sistine Chapel hotels

Property entrance
San Pietro Boutique Rooms

San Pietro Boutique Rooms

San Pietro Boutique Rooms
0.6 km from Sistine Chapel
10.0 out of 10, Exceptional, (915)
"Great place to stay in Rome. Quiet and less crowded. "
United States
Tanya
San Pietro Boutique Rooms
Front of property
Veniero37 Guest House

Veniero37 Guest House

Veniero37 Guest House
0.5 km from Sistine Chapel
10.0 out of 10, Exceptional, (16)
"Great location and Host was superb ! "
United States
Tom
The price is 3.650.008 ₫
4.448.729 ₫ total
includes taxes & fees
6 Jan - 7 Jan 2026
Veniero37 Guest House
Outdoor spa tub
Le Boutique Hotel

Le Boutique Hotel

Le Boutique Hotel
4.0 star property
0.3 km from Sistine Chapel
9.4 out of 10, Exceptional, (119)
"We really enjoyed our stay at Le boutique hotel. We loved the food, and friendly staff, the room was clean every day, the area was very safe to walk everywhere, especially very close to the Vatican. We highly recommend it. "
United States
Patricia
The price is 3.804.119 ₫
4.649.231 ₫ total
includes taxes & fees
12 Jan - 13 Jan 2026
Le Boutique Hotel
Free daily continental breakfast
B&B Roma Borgo 91

B&B Roma Borgo 91

B&B Roma Borgo 91
0.5 km from Sistine Chapel
9.8 out of 10, Exceptional, (63)
"Was very clean and wonderful. very much enjoyed our time there."
United States
Joseph
The price is 5.829.872 ₫
6.784.620 ₫ total
includes taxes & fees
8 Jan - 9 Jan 2026
B&B Roma Borgo 91
Premium bedding, memory-foam beds, minibar, in-room safe
Vatican Style

Vatican Style

Vatican Style
0.4 km from Sistine Chapel
9.2 out of 10, Wonderful, (852)
"Would definitely stay again when looking for close to Vatican location. "
United States
Kevin
The price is 2.901.314 ₫
3.501.246 ₫ total
includes taxes & fees
12 Jan - 13 Jan 2026
Vatican Style
Exterior
Passpartout Boutique Palace

Passpartout Boutique Palace

Passpartout Boutique Palace
0.5 km from Sistine Chapel
9.8 out of 10, Exceptional, (246)
"Excellent location, great dining options nearby, modern boutique hotel."
Canada
Matthew
The price is 3.287.330 ₫
4.049.783 ₫ total
includes taxes & fees
13 Jan - 14 Jan 2026
Passpartout Boutique Palace
Front of property
Hotel Sant' Anna

Hotel Sant' Anna

Hotel Sant' Anna
3.0 star property
0.5 km from Sistine Chapel
9.6 out of 10, Exceptional, (323)
"Wonderful location, very helpful service and staff!"
United States
Stephen
Hotel Sant' Anna
4 bedrooms, down duvets, minibar, in-room safe
Rest Guesthouse

Rest Guesthouse

Rest Guesthouse
0.5 km from Sistine Chapel
9.6 out of 10, Exceptional, (172)
"We really enjoyed our stay. The staff were very friendly and helpful and the location is perfect for sightseeing. "
United Kingdom
Peter
Rest Guesthouse
Property amenity
Residenza Paolo VI

Residenza Paolo VI

Residenza Paolo VI
0.3 km from Sistine Chapel
9.2 out of 10, Wonderful, (527)
"It was great stay all round"
Australia
Saad
Residenza Paolo VI
Exterior
SUITES 51

SUITES 51

SUITES 51
0.5 km from Sistine Chapel
9.6 out of 10, Exceptional, (21)
"Location is excellent, beside the Vatican and a short walk to all the main attractions in Rome. The suites are newly renovated with comfortable beds. Perfect spot."
United States
Sandy
The price is 2.230.560 ₫
2.825.376 ₫ total
includes taxes & fees
7 Jan - 8 Jan 2026
SUITES 51
Classic Double Room | Hypo-allergenic bedding, minibar, soundproofing, iron/ironing board
Vatican Jubilee

Vatican Jubilee

Vatican Jubilee
0.6 km from Sistine Chapel
9.6 out of 10, Exceptional, (58)
"Great place!"
United States
Hugo
The price is 1.967.633 ₫
2.536.156 ₫ total
includes taxes & fees
6 Jan - 7 Jan 2026
Vatican Jubilee
Deluxe Double or Twin Room, Balcony | Balcony
Starhotels Michelangelo

Starhotels Michelangelo

Starhotels Michelangelo
4.0 star property
0.5 km from Sistine Chapel
9.2 out of 10, Wonderful, (1000)
"Love this hotel "
United States
Tracy
The price is 5.745.382 ₫
6.784.620 ₫ total
includes taxes & fees
5 Jan - 6 Jan 2026
Starhotels Michelangelo
Front of property
Borgo Pio Suites Inn

Borgo Pio Suites Inn

Borgo Pio Suites Inn
0.4 km from Sistine Chapel
9.2 out of 10, Wonderful, (375)
"A great location close to St Peter’s Square. Lots of eateries close by as well. Rooms were good and very clean. "
United Kingdom
Duncan
The price is 3.141.481 ₫
3.827.389 ₫ total
includes taxes & fees
26 Dec - 27 Dec
Borgo Pio Suites Inn
Exterior detail
Eccelso Hotel

Eccelso Hotel

Eccelso Hotel
3.0 star property
0.6 km from Sistine Chapel
9.6 out of 10, Exceptional, (206)
"Great place, great service, great location! highly recommended"
Canada
Jensen
The price is 3.255.716 ₫
3.953.048 ₫ total
includes taxes & fees
20 Jan - 21 Jan 2026
Eccelso Hotel
Suite | Premium bedding, down duvets, in-room safe, desk
The Pope's Window

The Pope's Window

The Pope's Window
0.5 km from Sistine Chapel
9.4 out of 10, Exceptional, (412)
"The room was great except you can hear the pkumbing from the other rooms but nothing too bothersome it was very clean and very close to the St. Peters Basilica. A less than 5 min walk."
United States
Zuzell
The price is 2.934.454 ₫
3.599.659 ₫ total
includes taxes & fees
24 Dec - 25 Dec
The Pope's Window
Bar (on property)
The Spring House Hotel Rome Vatican, Tapestry Collection Hilton

The Spring House Hotel Rome Vatican, Tapestry Collection Hilton

The Spring House Hotel Rome Vatican, Tapestry Collection Hilton
4.0 star property
0.5 km from Sistine Chapel
9.2 out of 10, Wonderful, (1003)
"The buffet breakfast and sauna were great!"
United States
Kelvin S
The price is 4.069.645 ₫
4.941.310 ₫ total
includes taxes & fees
8 Jan - 9 Jan 2026
The Spring House Hotel Rome Vatican, Tapestry Collection Hilton
Superior Apartment, 1 Bedroom, Annex Building | 1 bedroom, down duvets, individually decorated, individually furnished
Folia B&B

Folia B&B

Folia B&B
0.6 km from Sistine Chapel
9.6 out of 10, Exceptional, (24)
"Great location, quiet, lovely property owner and staff . Would definitely stay again "
Australia
Simone
The price is 2.806.647 ₫
3.459.072 ₫ total
includes taxes & fees
7 Jan - 8 Jan 2026
Folia B&B
Family Suite, Balcony, City View | Terrace/patio
Tmark Hotel Vaticano

Tmark Hotel Vaticano

Tmark Hotel Vaticano
4.0 star property
0.4 km from Sistine Chapel
9.0 out of 10, Wonderful, (786)
"Great hotel, excellent service and the best location if visiting the Vatican "
United States
Mario
Tmark Hotel Vaticano
Property entrance
Vatican Relais Rome

Vatican Relais Rome

Vatican Relais Rome
0.5 km from Sistine Chapel
9.2 out of 10, Wonderful, (185)
"Loved this property! Staff was extremely friendly and helpful! Super close to the Vatican and a popular square with many food and shopping options! Had a great time! Very clean!"
United States
Jennifer
Vatican Relais Rome
Front of property
Velantia Vaticano - Guesthouse

Velantia Vaticano - Guesthouse

Velantia Vaticano - Guesthouse
0.6 km from Sistine Chapel
9.6 out of 10, Exceptional, (8)
"Great place to stay for a few days in Rome. Good location, great restaurant next door. Bed was super complicated. Would recommend for a couple or single person. "
Australia
Claudette
Velantia Vaticano - Guesthouse
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Sistine Chapel Hotel Reviews

Hotels near other Sistine Chapel attractions

St Peters Basilica, Rome, Italy

St. Peter's Basilica

4.7/5 (14,967 reviews)
You can learn about the local history of Vatican City when you visit a top site such as St. Peter's Basilica. Stroll along the riverfront or visit the churches in this vibrant area.
See properties
View from the top of the Vatican looking towards Castel Sant'Angelo
Photo by Andrew Manwaring
Open Photo by Andrew Manwaring

Vatican Necropolis

You can browse the exhibits at Vatican Necropolis, a museum with a storied past, during your travels to Vatican City. Stroll along the riverfront in this vibrant area or seek out the local tours.
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Frequently asked questions

What's the area like around Sistine Chapel?
Sistine Chapel is located in a historic area of Vatican City known for its stunning river views and stunning cathedral. If you're looking for a convenient place to stay, take a look at the 1183 hotels and other accommodation options you'll find within a mile.
How many hotels will I find close to Sistine Chapel?
Expedia has 1183 hotels and other accommodation options within a mile from Sistine Chapel.
If I need to cancel the hotel reservation for my stay near Sistine Chapel, will I receive a refund?
Yes! You'll find that most room reservations are fully refundable if you cancel before the accommodation's cancellation deadline, which is usually within 24-48 hours of your scheduled arrival. If your reservation is non-refundable, it might still be possible to cancel it and receive a refund within a 24-hour period of your booking. Enter your dates, click on "Search", then you can use the "fully refundable" filter to get the top deals on offer near Sistine Chapel.
What can I see and do near Sistine Chapel?
Vatican Museums, Castel Sant'Angelo and Cloister of Bramante feature captivating exhibits. Explore landmarks like Piazza Navona, Pantheon and Spanish Steps. You can catch a show at Paul VI Audience Hall, Auditorium Conciliazione and Sistina Theater.
How can I get to Sistine Chapel?
With so many choices for transport, seeing all of the area near Sistine Chapel is easy. You can walk to nearby metro stations including Ottaviano - San Pietro - Musei Vaticani Station, Risorgimento/S. Pietro Tram Stop and Milizie-Angelico Tram Stop. To venture out into the surrounding area, ride one of the trains from Rome Valle Aurelia Station or Rome San Pietro Station.