Search Hotels in South Island, Fort Myers Beach

Start date: Check-in selected.
To Date
End date: Check-out

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
9 Dec - 10 Dec
Tomorrow
10 Dec - 11 Dec
This weekend
12 Dec - 14 Dec
Next weekend
19 Dec - 21 Dec

Filter by

Guest rating
Guest rating
Star rating

Our top choices for South Island hotels

Condo | Terrace/patio
Pointe Estero Beach Resort

Pointe Estero Beach Resort

2.0 star property
South Island
9.2 out of 10, Wonderful, (1000)
"Could not beat the ocean view!!"
United States
BETH
The price is 5.509.658 ₫
14.704.724 ₫ total
includes taxes & fees
10 Dec - 11 Dec
Pointe Estero Beach Resort
Outdoor pool
GullWing Beach Resort

GullWing Beach Resort

3.5 star property
South Island
9.4 out of 10, Exceptional, (932)
"The view of the beach was spectacular. "
United States
Carol
GullWing Beach Resort
House | 2 bedrooms
Redfish Retreat - South End Pool Home

Redfish Retreat - South End Pool Home

2.0 star property
South Island
The price is 11.316.036 ₫
26.797.908 ₫ total
includes taxes & fees
8 Jan - 9 Jan 2026
Redfish Retreat - South End Pool Home
Aerial view
DiamondHead Beach Resort

DiamondHead Beach Resort

3.5 star property
6.5 km from South Island
9.0 out of 10, Wonderful, (1006)
"Everything about this resort is spectacular! Staff, amenities, room! We had a wonderful stay!"
United States
Minda
DiamondHead Beach Resort
Deluxe Studio, 1 King Bed, Marina View | View from room
Latitude 26 Waterfront Boutique Resort - Fort Myers Beach

Latitude 26 Waterfront Boutique Resort - Fort Myers Beach

2.5 star property
Siesta Isle, 9.2 km from South Island
8.8 out of 10, Excellent, (1000)
"Great Place to Stay!"
United States
JUDY
The price is 2.865.022 ₫
3.194.283 ₫ total
includes taxes & fees
14 Dec - 15 Dec
Latitude 26 Waterfront Boutique Resort - Fort Myers Beach
Interior entrance
Allure Suites

Allure Suites

3.0 star property
16 km from South Island
7.6 out of 10, Good, (1006)
"Liked the friendly and fast check-in, spacious and clean suite, great location close to stores, soundproof rooms, greetings when I returned each day and reasonable room rates. I would stay again. "
United States
Charles
Allure Suites
Suite with King Bed, Beachfront, Balcony | Terrace/patio
Lani Kai Beachfront Resort

Lani Kai Beachfront Resort

3.5 star property
7 km from South Island
9.0 out of 10, Wonderful, (1021)
"Clean rooms, friendly staff, so much to do there and nearby "
United States
Lisa R
The price is 3.787.045 ₫
4.810.451 ₫ total
includes taxes & fees
10 Dec - 11 Dec
Lani Kai Beachfront Resort
Exterior
Sanibel Inn

Sanibel Inn

3.0 star property
14.4 km from South Island
9.0 out of 10, Wonderful, (1001)
"Very nice hotel/resort. Clean, quiet, nice pool, attentive staff. Love the screened in balcony. "
Canada
Jonathan
The price is 7.403.368 ₫
9.783.223 ₫ total
includes taxes & fees
14 Dec - 15 Dec
Sanibel Inn
Exterior
Holiday Inn Express & Suites Ft Myers Beach-Sanibel Gateway by IHG

Holiday Inn Express & Suites Ft Myers Beach-Sanibel Gateway by IHG

2.5 star property
9.7 km from South Island
9.4 out of 10, Exceptional, (1006)
"Great rooms, good staff"
United States
Dedan
The price is 2.557.114 ₫
2.851.314 ₫ total
includes taxes & fees
14 Dec - 15 Dec
Holiday Inn Express & Suites Ft Myers Beach-Sanibel Gateway by IHG
Bar (on property)
Matanzas Inn Bayside Resort and Marina

Matanzas Inn Bayside Resort and Marina

3.0 star property
7.4 km from South Island
9.2 out of 10, Wonderful, (1014)
"Was great location "
United States
Jose
The price is 3.163.440 ₫
4.186.286 ₫ total
includes taxes & fees
10 Dec - 11 Dec
Matanzas Inn Bayside Resort and Marina
Free buffet breakfast
Holiday Inn Express Cape Coral-Fort Myers Area by IHG

Holiday Inn Express Cape Coral-Fort Myers Area by IHG

2.5 star property
17.3 km from South Island
9.4 out of 10, Exceptional, (1029)
"Hotel was very clean and the breakfast had a great variety."
United States
Lynn
The price is 2.978.906 ₫
3.321.480 ₫ total
includes taxes & fees
14 Dec - 15 Dec
Holiday Inn Express Cape Coral-Fort Myers Area by IHG
2 outdoor pools, pool cabanas (surcharge), pool umbrellas
The Perry Hotel Naples

The Perry Hotel Naples

4.5 star property
17.4 km from South Island
9.6 out of 10, Exceptional, (514)
"Great hotel! "
United States
David
The price is 4.779.431 ₫
6.621.950 ₫ total
includes taxes & fees
11 Dec - 12 Dec
The Perry Hotel Naples
Outdoor pool, open 8:00 AM to 10:00 PM, pool cabanas (surcharge)
The Westin Cape Coral Resort At Marina Village

The Westin Cape Coral Resort At Marina Village

4.0 star property
17.4 km from South Island
9.0 out of 10, Wonderful, (1004)
"Excellent stay over Thanksgiving holiday!"
United States
Nicole
The price is 3.856.233 ₫
5.301.398 ₫ total
includes taxes & fees
21 Dec - 22 Dec
The Westin Cape Coral Resort At Marina Village
Outdoor pool, open 8:00 AM to 10:00 PM, pool umbrellas
Hampton Inn & Suites Fort Myers Beach/Sanibel Gateway

Hampton Inn & Suites Fort Myers Beach/Sanibel Gateway

3.0 star property
9.8 km from South Island
8.4 out of 10, Very good, (1003)
"Everything about this stay was wonderful. "
United States
John
The price is 2.720.558 ₫
3.033.423 ₫ total
includes taxes & fees
15 Dec - 16 Dec
Hampton Inn & Suites Fort Myers Beach/Sanibel Gateway
View from room
Matlacha on Shoreview

Matlacha on Shoreview

2.0 star property
30.1 km from South Island
9.6 out of 10, Exceptional, (210)
"Place was great. Nice and neat perfect for what i needed."
United States
Michael
The price is 1.186.290 ₫
3.086.331 ₫ total
includes taxes & fees
14 Dec - 15 Dec
Matlacha on Shoreview
Outdoor pool
Sanibel Island Beach Resort

Sanibel Island Beach Resort

3.0 star property
15.2 km from South Island
9.2 out of 10, Wonderful, (1456)
"Nice location and friendly staff. The access to the beach is easy "
United States
Henrik C
The price is 5.509.658 ₫
6.802.319 ₫ total
includes taxes & fees
10 Dec - 11 Dec
Sanibel Island Beach Resort
Exercise/lap pool
Hyatt Vacation Club at Coconut Cove, Bonita Springs

Hyatt Vacation Club at Coconut Cove, Bonita Springs

4.0 star property
5.9 km from South Island
9.2 out of 10, Wonderful, (724)
"Very pleasant staff, helpful, property well maintained. Great vacation spot with activities for the whole family. "
United States
Mutessa
The price is 4.341.459 ₫
5.869.459 ₫ total
includes taxes & fees
17 Dec - 18 Dec
Hyatt Vacation Club at Coconut Cove, Bonita Springs
Lobby sitting area
Hilton Naples

Hilton Naples

4.0 star property
24.5 km from South Island
9.2 out of 10, Wonderful, (1328)
"Nice reception, nice hotel , good location."
United States
Juan
The price is 4.950.256 ₫
5.494.785 ₫ total
includes taxes & fees
16 Dec - 17 Dec
Hilton Naples
Exterior
Margaritaville Beach Resort Fort Myers

Margaritaville Beach Resort Fort Myers

4.0 star property
7.2 km from South Island
9.0 out of 10, Wonderful, (1694)
"Great place "
United States
Debra Sue
The price is 4.721.434 ₫
6.587.244 ₫ total
includes taxes & fees
10 Dec - 11 Dec
Margaritaville Beach Resort Fort Myers
Outdoor pool
Residence Inn by Marriott Fort Myers Sanibel

Residence Inn by Marriott Fort Myers Sanibel

3.0 star property
11.8 km from South Island
8.6 out of 10, Excellent, (1003)
"Clean room, wonderful staff, and nice breakfast. "
United States
Danielle
The price is 2.504.390 ₫
2.792.395 ₫ total
includes taxes & fees
14 Dec - 15 Dec
Residence Inn by Marriott Fort Myers Sanibel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Where to stay in South Island

Find the best South Island areas for the activities you enjoy most.

Mid Island

While visiting Mid Island, you might make a stop by sights like Estero Boulevard Beach and Sterling Ave Beach.

TP Hill's

When in TP Hill's, you can plan a visit to Key West Express and Estero Boulevard Beach, some noteworthy sights in the nearby area.

Downtown Fort Myers Beach

If you're spending some time in Downtown Fort Myers Beach, Lynn Hall Memorial Park and Estero Boulevard Beach are top sights worth seeing.

Laguna Shores

While Laguna Shores may not have many sights to explore, venturing just a little farther will lead you to top things to see and do like Lover's Key Beach and Santini Marina Shopping Plaza.

Winklers

Winklers might not have many top sights, but Key West Express and Estero Boulevard Beach are two attractions nearby that you can check out.

Top South Island Hotel Reviews

Pointe Estero Beach Resort

Pointe Estero Beach Resort

10/10 Excellent
"Everything was perfect. "
David 4-night trip
Posted 3 weeks ago
Pointe Estero Beach Resort

Explore a world of travel with Expedia

Frequently asked questions

What's it like in South Island?
Travellers to Fort Myers Beach's South Island neighbourhood will be sure to enjoy a stay here. Make sure that you visit Santini Marina Shopping Plaza and Castle Beach as part of your South Island travel plans.
How many hotels will I find in South Island?
Expedia has 1148 hotels and other accommodation options in South Island to choose from, making this an ideal home base for exploring the greater Fort Myers Beach area.
If I need to cancel my hotel reservation in South Island, will I receive a refund?
Yes! You'll find that most hotel bookings are refundable provided that you cancel prior to the hotel's cancellation deadline, which often is within 24-48 hours of the scheduled arrival. If you booked a non-refundable reservation, you may still be able to cancel and be given a refund within a 24-hour period of your booking. Enter your dates, click on "Search", then use the "fully refundable" filter to get the best deals in South Island.
What is there to do around this Fort Myers Beach neighbourhood?
Dip your toes in the water at Castle Beach or Sterling Ave Beach while you're in South Island. You could also plan a visit to Santini Marina Shopping Plaza or Big Carlos Pass while you're in the neighbourhood. A few places to visit in the area around South Island include Lover's Key Beach, Mound Key Archaeological State Park and Hell Peckney Bay. Mound House and Bonita Beach Dog Park are also worth a visit when you're out sightseeing in Fort Myers Beach.