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Check availability on South Loop Business Hotels

Our top choices for South Loop business-friendly hotels

Hilton Chicago

Hilton Chicago
4.0 star property
Downtown Chicago
8.4 out of 10, Very good, (2381)
"We had a great stay and will be back again."
United States
Amber
The price is 2.998.472 ₫
3.519.907 ₫ total
includes taxes & fees
23 Dec - 24 Dec
Hilton Chicago

Hilton Garden Inn Chicago Downtown South Loop

Hilton Garden Inn Chicago Downtown South Loop
3.0 star property
Downtown Chicago
8.8 out of 10, Excellent, (1760)
"Clean and staff was courteous. "
United States
HANNAH
The price is 1.873.058 ₫
2.198.476 ₫ total
includes taxes & fees
5 Jan - 6 Jan 2026
Hilton Garden Inn Chicago Downtown South Loop

Congress Plaza Hotel

Congress Plaza Hotel
3.5 star property
Downtown Chicago
8.0 out of 10, Very good, (9662)
"Great hotel and staff. "
Canada
Dane
The price is 5.421.873 ₫
6.364.734 ₫ total
includes taxes & fees
31 Dec - 1 Jan 2026
Congress Plaza Hotel

Bluegreen Vacations Hotel Blake, an Ascend Collection Hotel

Bluegreen Vacations Hotel Blake, an Ascend Collection Hotel
4.0 star property
Downtown Chicago
9.6 out of 10, Exceptional, (1120)
"Amazing hotel "
United States
Alondra
The price is 2.504.426 ₫
2.939.945 ₫ total
includes taxes & fees
5 Jan - 6 Jan 2026
Bluegreen Vacations Hotel Blake, an Ascend Collection Hotel

Homewood Suites by Hilton Chicago Downtown South Loop

Homewood Suites by Hilton Chicago Downtown South Loop
3.0 star property
Downtown Chicago
8.8 out of 10, Excellent, (2143)
"Very nice place"
United States
Salman
The price is 2.083.514 ₫
2.445.836 ₫ total
includes taxes & fees
5 Jan - 6 Jan 2026
Homewood Suites by Hilton Chicago Downtown South Loop

Le Méridien Essex Chicago

Le Méridien Essex Chicago
4.0 star property
Downtown Chicago
8.6 out of 10, Excellent, (1004)
"Great stay for quick weekend trip "
United States
Natali
The price is 2.174.274 ₫
3.015.646 ₫ total
includes taxes & fees
5 Jan - 6 Jan 2026
Le Méridien Essex Chicago

Sentral Michigan Avenue

Sentral Michigan Avenue
4.0 star property
Downtown Chicago
9.2 out of 10, Wonderful, (1009)
"This place made a great landing spot for a holiday weekend w family. Clean, great location, loved the holiday decorations and indoor pool / outside hot tub. Will stay again! "
United States
Deidre
The price is 3.108.172 ₫
4.420.628 ₫ total
includes taxes & fees
21 Dec - 22 Dec
Sentral Michigan Avenue

The Blackstone, Autograph Collection

The Blackstone, Autograph Collection
4.0 star property
Downtown Chicago
9.0 out of 10, Wonderful, (1003)
"Great staff, beds and pillows very comfortable "
United States
Marty
The price is 3.262.594 ₫
4.602.333 ₫ total
includes taxes & fees
21 Dec - 22 Dec
The Blackstone, Autograph Collection

Hampton Inn Chicago McCormick Place

Hampton Inn Chicago McCormick Place
3.0 star property
Near South Side
9.0 out of 10, Wonderful, (1019)
"Everything was Wonderful great hotel great location "
United States
Shena
The price is 2.020.378 ₫
2.371.840 ₫ total
includes taxes & fees
10 Jan - 11 Jan 2026
Hampton Inn Chicago McCormick Place

Home2 Suites by Hilton Chicago McCormick Place

Home2 Suites by Hilton Chicago McCormick Place
3.0 star property
Near South Side
9.2 out of 10, Wonderful, (728)
"Location, very spacious rooms, great breakfast!!! Excellent customer service!!! Will be staying there again. "
United States
Bianca
The price is 1.873.058 ₫
2.198.781 ₫ total
includes taxes & fees
23 Dec - 24 Dec
Home2 Suites by Hilton Chicago McCormick Place
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top South Loop Hotel Reviews

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Frequently asked questions

Why book your business-friendly hotel in South Loop with Expedia?
With conveniences like meeting rooms, 24-hour room service and on-site cafés, our business-friendly accommodation come with everything you'll need to settle that big contract — and then relax in the comfort of your room. Enter your destination and preferred travel dates and Expedia will help you do the rest.
How can I find cheap business-friendly hotels in South Loop?
When work takes you to South Loop, our "business friendly" filter will help you find the right hotel. From dependable WiFi to concierge services and conference spaces, they have the amenities you need for a comfortable and productive stay. Another tip? Refine your search by your budget and preferred star rating to see the cheapest accommodation.