Search Hotels Near South Main, Vancouver

Start date: Check-in selected.
To Date
End date: Check-out

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
16 Dec - 17 Dec
Tomorrow
17 Dec - 18 Dec
This weekend
19 Dec - 21 Dec
Next weekend
26 Dec - 28 Dec

Filter by

Guest rating
Guest rating
Star rating

Our top choices for South Main hotels

Family Apartment | Premium bedding, pillow-top beds, blackout curtains, soundproofing
Smithe House

Smithe House

Smithe House
4.0 star property
Yaletown, 2.7 km from South Main
10.0 out of 10, Exceptional, (349)
"Everything was perfect staff were amazing location perfect apartment was spotless "
Australia
Andrea
The price is 4.059.224 ₫
4.837.581 ₫ total
includes taxes & fees
18 Dec - 19 Dec
Smithe House
Room, 1 King Bed (Secret Garden) | Egyptian cotton sheets, premium bedding, down duvets, pillow-top beds
OPUS Hotel Vancouver

OPUS Hotel Vancouver

OPUS Hotel Vancouver
4.0 star property
Yaletown, 2.6 km from South Main
9.6 out of 10, Exceptional, (1052)
"Wonderful staff, rooms, and location. "
United States
Mary
OPUS Hotel Vancouver
Front of property – evening/night
Hotel Blu Vancouver

Hotel Blu Vancouver

Hotel Blu Vancouver
4.0 star property
Downtown Vancouver, 2.7 km from South Main
9.6 out of 10, Exceptional, (3468)
"Nice clean rooms, great location."
Canada
Halyna
The price is 3.905.471 ₫
4.713.103 ₫ total
includes taxes & fees
18 Dec - 19 Dec
Hotel Blu Vancouver
55-inch flat-screen TV with digital channels, TV
Georgian Court Hotel, WorldHotels Elite

Georgian Court Hotel, WorldHotels Elite

Georgian Court Hotel, WorldHotels Elite
4.0 star property
Downtown Vancouver, 2.7 km from South Main
9.4 out of 10, Exceptional, (3758)
"Great location; loved the hot tub and Sauna"
Canada
Evelyne
The price is 3.611.713 ₫
4.358.516 ₫ total
includes taxes & fees
22 Dec - 23 Dec
Georgian Court Hotel, WorldHotels Elite
Breakfast, lunch, dinner served; local cuisine, al fresco dining
Granville Island Hotel

Granville Island Hotel

Granville Island Hotel
3.5 star property
Granville Island, 2.7 km from South Main
9.4 out of 10, Exceptional, (1236)
"Very nice hotel, I really love the location. "
Canada
Gary
The price is 4.316.093 ₫
5.208.320 ₫ total
includes taxes & fees
23 Dec - 24 Dec
Granville Island Hotel
Breakfast area
Windsor Guest House

Windsor Guest House

Windsor Guest House
2.5 star property
Mount Pleasant, 1 km from South Main
9.2 out of 10, Wonderful, (282)
"Very good location, clean, nice breakfast, good value for the cost!"
Canada
Diana R
The price is 2.493.802 ₫
2.971.989 ₫ total
includes taxes & fees
19 Dec - 20 Dec
Windsor Guest House
Loft, 1 Bedroom | Living area | 55-inch TV with cable channels, Netflix, pay films
JW Marriott Parq Vancouver

JW Marriott Parq Vancouver

JW Marriott Parq Vancouver
5.0 star property
Downtown Vancouver, 2.3 km from South Main
9.2 out of 10, Wonderful, (1003)
"Nice rooms, quiet & clean"
Canada
Thomas
The price is 5.350.686 ₫
6.376.679 ₫ total
includes taxes & fees
4 Jan - 5 Jan 2026
JW Marriott Parq Vancouver
View from property
Rosedale On Robson Suite Hotel

Rosedale On Robson Suite Hotel

Rosedale On Robson Suite Hotel
3.5 star property
Downtown Vancouver, 2.8 km from South Main
9.2 out of 10, Wonderful, (3163)
"We really enjoyed our stay and the location was very convenient."
Canada
Raylene
The price is 3.802.809 ₫
4.532.222 ₫ total
includes taxes & fees
21 Dec - 22 Dec
Rosedale On Robson Suite Hotel
Exterior
the DOUGLAS, Autograph Collection

the DOUGLAS, Autograph Collection

the DOUGLAS, Autograph Collection
5.0 star property
Downtown Vancouver, 2.4 km from South Main
9.2 out of 10, Wonderful, (836)
"Clean room, quick check-in, great location, and friendly staff. "
United States
Tyler
The price is 5.140.481 ₫
6.126.168 ₫ total
includes taxes & fees
4 Jan - 5 Jan 2026
the DOUGLAS, Autograph Collection
Lobby lounge
Residence Inn by Marriott Vancouver Downtown

Residence Inn by Marriott Vancouver Downtown

Residence Inn by Marriott Vancouver Downtown
3.0 star property
Downtown Vancouver, 3.2 km from South Main
9.2 out of 10, Wonderful, (1126)
"It was a lovely hotel"
Canada
Emily
The price is 3.195.124 ₫
3.807.789 ₫ total
includes taxes & fees
4 Jan - 5 Jan 2026
Residence Inn by Marriott Vancouver Downtown
Bar (on property)
Hilton Vancouver Downtown

Hilton Vancouver Downtown

Hilton Vancouver Downtown
4.5 star property
Downtown Vancouver, 2.9 km from South Main
9.2 out of 10, Wonderful, (1003)
"Great location, our plan had breakfast included that really worth it, staff very friendly "
United States
Silvia
The price is 3.745.098 ₫
4.519.413 ₫ total
includes taxes & fees
23 Dec - 24 Dec
Hilton Vancouver Downtown
Outdoor pool, a heated pool
Level Vancouver - Yaletown Seymour

Level Vancouver - Yaletown Seymour

Level Vancouver - Yaletown Seymour
4.0 star property
Downtown Vancouver, 2.9 km from South Main
9.2 out of 10, Wonderful, (542)
"Very nice hotel in a great location. Will definitely being staying here again "
Canada
Rory
The price is 4.230.291 ₫
5.104.746 ₫ total
includes taxes & fees
14 Jan - 15 Jan 2026
Level Vancouver - Yaletown Seymour
Rooftop terrace
YWCA Hotel

YWCA Hotel

YWCA Hotel
2.5 star property
Downtown Vancouver, 2.7 km from South Main
9.0 out of 10, Wonderful, (3073)
"Staff was awesome and the room was very clean!"
Canada
Reese
The price is 2.184.226 ₫
2.635.822 ₫ total
includes taxes & fees
4 Jan - 5 Jan 2026
YWCA Hotel
Pool
Hampton Inn and Suites by Hilton, Downtown Vancouver

Hampton Inn and Suites by Hilton, Downtown Vancouver

Hampton Inn and Suites by Hilton, Downtown Vancouver
3.5 star property
Downtown Vancouver, 2.6 km from South Main
9.0 out of 10, Wonderful, (1688)
"Room large n very clean, staff very friendly "
United States
Marcela
The price is 3.431.701 ₫
4.141.218 ₫ total
includes taxes & fees
4 Jan - 5 Jan 2026
Hampton Inn and Suites by Hilton, Downtown Vancouver
Exterior
Best Western Premier Chateau Granville Hotel & Suites & Conf. Centre

Best Western Premier Chateau Granville Hotel & Suites & Conf. Centre

Best Western Premier Chateau Granville Hotel & Suites & Conf. Centre
3.5 star property
Downtown Vancouver, 3 km from South Main
9.0 out of 10, Wonderful, (1016)
"Had a very pleasant stay! All staff was kind and helpful "
Canada
Aleksandra
The price is 2.995.429 ₫
3.569.803 ₫ total
includes taxes & fees
4 Jan - 5 Jan 2026
Best Western Premier Chateau Granville Hotel & Suites & Conf. Centre
Breakfast served
Hotel Belmont Vancouver - MGallery Collection

Hotel Belmont Vancouver - MGallery Collection

Hotel Belmont Vancouver - MGallery Collection
4.0 star property
Downtown Vancouver, 3 km from South Main
9.0 out of 10, Wonderful, (1669)
"Great place to stay "
United States
Diego Martinez
The price is 3.250.542 ₫
4.009.743 ₫ total
includes taxes & fees
19 Dec - 20 Dec
Hotel Belmont Vancouver - MGallery Collection
Staircase
Victorian Hotel

Victorian Hotel

Victorian Hotel
3.0 star property
Chinatown, 3.1 km from South Main
9.0 out of 10, Wonderful, (1172)
"It was nice in general, room was clean, staff was nice and helpful, location was good."
Canada
Nabeel
The price is 2.738.636 ₫
3.263.654 ₫ total
includes taxes & fees
18 Dec - 19 Dec
Victorian Hotel
Exterior detail
Douglas Guest House

Douglas Guest House

Douglas Guest House
2.5 star property
Mount Pleasant, 1 km from South Main
8.8 out of 10, Excellent, (336)
"Parking was convenient and safe! "
Canada
Sheila
The price is 3.009.761 ₫
3.587.253 ₫ total
includes taxes & fees
11 Jan - 12 Jan 2026
Douglas Guest House
Garden
Cambie Lodge B&B

Cambie Lodge B&B

Cambie Lodge B&B
3.0 star property
Mount Pleasant, 1 km from South Main
8.8 out of 10, Excellent, (353)
"Check-in was easy, staff were friendly, breakfast was good, and rooms were clean. I would stay again."
Canada
Estefania
The price is 2.923.768 ₫
3.484.443 ₫ total
includes taxes & fees
23 Dec - 24 Dec
Cambie Lodge B&B
Breakfast served
The Parker Hotel and Rooftop

The Parker Hotel and Rooftop

The Parker Hotel and Rooftop
4.0 star property
Downtown Vancouver, 3.1 km from South Main
8.8 out of 10, Excellent, (1835)
"Amazing check in. Awesome location!"
Canada
Stephen
The price is 2.847.330 ₫
3.436.288 ₫ total
includes taxes & fees
22 Dec - 23 Dec
The Parker Hotel and Rooftop
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top South Main Hotel Reviews

Windsor Guest House

Windsor Guest House

10/10 Excellent
"Great location and facilities. Very convenient. "
Mijail 2-night trip
Posted 11 days ago
Windsor Guest House

Hotels near other South Main attractions

Olympic Village - Aqua Bus in Vancouver, BC. The view on the public transport boat with passengers on. Cityscape - Downtown and mountains in the background.

Olympic Village

You can find out about the history of Vancouver with a trip to Olympic Village. Attend a sporting event or visit the shops in this vibrant area.
See properties
ancouver, British Columbia / CANADA - Jul 25 2014: False Creek in a sunny summer day

Science World

4.4/5 (266 reviews)
You can spend time browsing the exhibits at Science World during your trip to Vancouver. Discover the top-notch restaurants and fascinating museums in this vibrant area.
See properties

Frequently asked questions

What's the area like around South Main?
South Main is located in Vancouver. If you're looking for a convenient place to stay, take a look at the 91 hotels and other accommodation options you'll find within a mile.
How many hotels will I be able to find near South Main?
Expedia has 91 hotels and other accommodation options within a mile from South Main.
If I need to cancel the hotel reservation for my stay near South Main, will I receive a refund?
Yes, most hotel room reservations are fully refundable if cancelled before the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of your scheduled arrival. If your reservation is non-refundable, it might still be possible to cancel it and get a refund within 24 hours of your booking. Plug in your dates, click on "Search", then you can use the "fully refundable" filter to review the best deals near South Main.
What can I see and do near South Main?
Science World, Vancouver Art Gallery and Museum of Vancouver feature captivating exhibits. Hotel Europe, Engine 374 Pavilion and Chinatown Millennium Gate are monuments to see when you're exploring the area around South Main. You can catch a show at Rickshaw Theatre, Queen Elizabeth Theatre and Orpheum Theater.
How can I get to South Main?
With so many ways to get around, seeing the area around South Main is a breeze. Nearby metro stations include Nanaimo Station, 29th Avenue Station and Commercial-Broadway Station. If you're hopping a train into town, Vancouver Rocky Mountaineer Station, Vancouver, BC (XEA-Vancouver Pacific Central Station) and Pacific Central Station are the closest train stations to East Vancouver.

Explore a world of travel with Expedia