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15 Dec - 16 Dec
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16 Dec - 17 Dec
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19 Dec - 21 Dec
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26 Dec - 28 Dec

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Our top choices for South Mission Beach hotels

3 restaurants, breakfast, lunch, dinner served; Regional cuisine
Wyndham San Diego Bayside

Wyndham San Diego Bayside

Wyndham San Diego Bayside
4.0 star property
9.1 km from South Mission Beach
8.4 out of 10, Very good, (6066)
"Always an amazing stay"
United States
Jana
The price is 3.555.391 ₫
4.885.201 ₫ total
includes taxes & fees
23 Dec - 24 Dec
Wyndham San Diego Bayside
View from room
Courtyard by Marriott San Diego Downtown Little Italy

Courtyard by Marriott San Diego Downtown Little Italy

Courtyard by Marriott San Diego Downtown Little Italy
4.0 star property
Little Italy, 9.5 km from South Mission Beach
9.2 out of 10, Wonderful, (102)
"It was a nice place to stay at"
United States
Eric
The price is 2.893.770 ₫
3.355.182 ₫ total
includes taxes & fees
4 Jan - 5 Jan 2026
Courtyard by Marriott San Diego Downtown Little Italy
Exterior
Hampton Inn San Diego/Mission Valley

Hampton Inn San Diego/Mission Valley

Hampton Inn San Diego/Mission Valley
2.5 star property
6.7 km from South Mission Beach
8.8 out of 10, Excellent, (1290)
"Hotel was very clean and the staff was very friendly"
United States
Norma
The price is 2.462.335 ₫
2.830.331 ₫ total
includes taxes & fees
5 Jan - 6 Jan 2026
Hampton Inn San Diego/Mission Valley
2 outdoor pools, a heated pool, pool loungers
The Dana on Mission Bay

The Dana on Mission Bay

The Dana on Mission Bay
3.5 star property
Mission Bay, 1.5 km from South Mission Beach
9.0 out of 10, Wonderful, (3929)
"Always love staying here. Staff was very courteous and the rooms very clean. "
United States
Eric
The price is 3.656.673 ₫
4.729.302 ₫ total
includes taxes & fees
17 Dec - 18 Dec
The Dana on Mission Bay
Terrace/patio
DoubleTree by Hilton Hotel San Diego - Mission Valley

DoubleTree by Hilton Hotel San Diego - Mission Valley

DoubleTree by Hilton Hotel San Diego - Mission Valley
4.0 star property
8.8 km from South Mission Beach
8.4 out of 10, Very good, (1413)
"Great hotel in a great area - would definitely stay here again."
United States
Bhupinder
The price is 3.106.331 ₫
3.570.572 ₫ total
includes taxes & fees
4 Jan - 5 Jan 2026
DoubleTree by Hilton Hotel San Diego - Mission Valley
Poolside bar
Hard Rock Hotel San Diego

Hard Rock Hotel San Diego

Hard Rock Hotel San Diego
4.0 star property
Gaslamp Quarter, 10.8 km from South Mission Beach
9.0 out of 10, Wonderful, (3155)
"Great stay"
United States
Laurence
The price is 4.474.821 ₫
6.397.600 ₫ total
includes taxes & fees
21 Dec - 22 Dec
Hard Rock Hotel San Diego
Outdoor pool, pool umbrellas, pool loungers
Handlery Hotel

Handlery Hotel

Handlery Hotel
3.5 star property
7.6 km from South Mission Beach
8.2 out of 10, Very good, (2234)
"Staff was amazing and very accommodating. Always recommended staying here. "
United States
Taja
Handlery Hotel
Exterior
Manchester Grand Hyatt San Diego

Manchester Grand Hyatt San Diego

Manchester Grand Hyatt San Diego
4.0 star property
Marina District, 10 km from South Mission Beach
9.0 out of 10, Wonderful, (2873)
"Great Location....tons of walking from the hotel Front desk were very nice and polite will be coming back for sure "
United States
Carlos
The price is 4.630.032 ₫
6.801.759 ₫ total
includes taxes & fees
17 Dec - 18 Dec
Manchester Grand Hyatt San Diego
Lobby sitting area
Kings Inn San Diego

Kings Inn San Diego

Kings Inn San Diego
2.5 star property
7.3 km from South Mission Beach
8.8 out of 10, Excellent, (3577)
"Room was very clean, and the breakfast was good"
United States
Roxana
The price is 1.969.474 ₫
2.259.971 ₫ total
includes taxes & fees
17 Dec - 18 Dec
Kings Inn San Diego
Exterior
Holiday Inn Express San Diego Airport - Old Town by IHG

Holiday Inn Express San Diego Airport - Old Town by IHG

Holiday Inn Express San Diego Airport - Old Town by IHG
2.5 star property
6.6 km from South Mission Beach
9.2 out of 10, Wonderful, (1042)
"Excellent staff,breakfast,transportation "
United States
Weldon
The price is 3.577.752 ₫
4.112.447 ₫ total
includes taxes & fees
23 Dec - 24 Dec
Holiday Inn Express San Diego Airport - Old Town by IHG
Outdoor pool, a heated pool
Days Inn by Wyndham San Diego Hotel Circle

Days Inn by Wyndham San Diego Hotel Circle

Days Inn by Wyndham San Diego Hotel Circle
3.0 star property
8 km from South Mission Beach
8.0 out of 10, Very good, (2437)
"All was very nice. "
United States
Milton
The price is 2.214.155 ₫
2.545.060 ₫ total
includes taxes & fees
18 Dec - 19 Dec
Days Inn by Wyndham San Diego Hotel Circle
Lobby
Legacy Resort Hotel & Spa

Legacy Resort Hotel & Spa

Legacy Resort Hotel & Spa
4.0 star property
7.8 km from South Mission Beach
9.2 out of 10, Wonderful, (2952)
"Everything was super comfortable and the room was surprisingly affordable for the amenities you get. We will definitely stay there again if we go to San Diego."
United States
Eric
The price is 4.002.610 ₫
4.600.800 ₫ total
includes taxes & fees
23 Dec - 24 Dec
Legacy Resort Hotel & Spa
Front of property
The Sofia Hotel

The Sofia Hotel

The Sofia Hotel
3.5 star property
10 km from South Mission Beach
8.4 out of 10, Very good, (1664)
"Great location and history to the hotel "
United States
Stephanie
The Sofia Hotel
Outdoor pool, pool loungers
Best Western Plus Hacienda Hotel Old Town

Best Western Plus Hacienda Hotel Old Town

Best Western Plus Hacienda Hotel Old Town
3.0 star property
Old Town San Diego, 5.7 km from South Mission Beach
8.4 out of 10, Very good, (1865)
"Excellent location, courteous staff, great airport shuttle, delicious on-site restaurant."
United States
Kathleen
The price is 2.936.419 ₫
3.375.266 ₫ total
includes taxes & fees
21 Dec - 22 Dec
Best Western Plus Hacienda Hotel Old Town
Terrace/patio
DoubleTree by Hilton San Diego - Del Mar

DoubleTree by Hilton San Diego - Del Mar

DoubleTree by Hilton San Diego - Del Mar
4.0 star property
Carmel Valley, 19.1 km from South Mission Beach
8.4 out of 10, Very good, (1891)
"Excellent location"
United States
Paolo
The price is 2.642.275 ₫
3.010.741 ₫ total
includes taxes & fees
4 Jan - 5 Jan 2026
DoubleTree by Hilton San Diego - Del Mar
Exterior
Bay Club Hotel & Marina

Bay Club Hotel & Marina

Bay Club Hotel & Marina
3.5 star property
6.1 km from South Mission Beach
9.2 out of 10, Wonderful, (3192)
"Great stay and location!"
United States
Jason
The price is 3.243.653 ₫
3.728.417 ₫ total
includes taxes & fees
4 Jan - 5 Jan 2026
Bay Club Hotel & Marina
Outdoor pool, pool umbrellas, pool loungers
Homewood Suites by Hilton San Diego Hotel Circle/SeaWorld Area

Homewood Suites by Hilton San Diego Hotel Circle/SeaWorld Area

Homewood Suites by Hilton San Diego Hotel Circle/SeaWorld Area
3.0 star property
6.6 km from South Mission Beach
8.8 out of 10, Excellent, (1301)
"Great location from restaurants and shopping malls and just 15. Min away from downtown The rooms.are great big highly recommend it "
United States
Carlos Gabriel
The price is 2.989.043 ₫
3.435.756 ₫ total
includes taxes & fees
22 Dec - 23 Dec
Homewood Suites by Hilton San Diego Hotel Circle/SeaWorld Area
Beach nearby, beach towels
Hampton Inn Cardiff Beach Encinitas, CA

Hampton Inn Cardiff Beach Encinitas, CA

Hampton Inn Cardiff Beach Encinitas, CA
3.0 star property
29.3 km from South Mission Beach
9.2 out of 10, Wonderful, (1046)
"Clean room and staff were excellent."
United States
Jose
The price is 2.998.472 ₫
3.298.319 ₫ total
includes taxes & fees
13 Jan - 14 Jan 2026
Hampton Inn Cardiff Beach Encinitas, CA
3 bars/lounges, lobby lounge, cocktail bar, cocktail bar
Lafayette Hotel & Club

Lafayette Hotel & Club

Lafayette Hotel & Club
4.0 star property
10.6 km from South Mission Beach
9.4 out of 10, Exceptional, (1338)
"My wife loved everything about this vintage hotel."
United States
Eddie
The price is 6.024.303 ₫
6.912.953 ₫ total
includes taxes & fees
29 Dec - 30 Dec
Lafayette Hotel & Club
Room, 1 King Bed with Sofa bed, Marina View | View from room
Sheraton San Diego Resort

Sheraton San Diego Resort

Sheraton San Diego Resort
4.0 star property
6.7 km from South Mission Beach
8.2 out of 10, Very good, (3185)
"Great stay! "
United States
Melissa
The price is 2.946.384 ₫
4.333.772 ₫ total
includes taxes & fees
6 Jan - 7 Jan 2026
Sheraton San Diego Resort
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Where to stay in South Mission Beach

Find the best South Mission Beach areas for the activities you enjoy most.

Downtown San Diego

Known for its fantastic nightlife, fascinating museums and beautiful waterfront views, there's plenty to explore in Downtown San Diego. Top attractions like Petco Park and Port of San Diego are major draws. Catch the metro at Civic Center Station or Civic Center Station to see more of the city.

Gaslamp Quarter featuring a bar, night scenes and street scenes

Gaslamp Quarter

Cosy bars interesting history and top sights from Gaslamp Museum at the Davis-Horton House to Lyceum Theatre – discover Gaslamp Quarter, a destination also famous for its shopping.

Pacific Beach Park showing a beach

Pacific Beach

The stunning beaches and fantastic nightlife are just a few highlights of Pacific Beach. Make a stop by Mission Bay or Crystal Pier while you're exploring the area.

Belmont Park featuring a park and rides

Mission Beach

If you're spending some time in Mission Beach, Mission Beach and Mission Bay are top sights worth seeing.

Ocean Beach

Ocean Beach is beloved for its stunning beaches. Take some time to explore sights in the area like Ocean Beach Pier and Dog Beach.

Top South Mission Beach Hotel Reviews

Courtyard by Marriott San Diego Downtown Little Italy

Courtyard by Marriott San Diego Downtown Little Italy

10/10 Excellent
"Clean rooms, friendly staff"
Marie 1-night trip
Posted 1 day ago
Courtyard by Marriott San Diego Downtown Little Italy

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Frequently asked questions

What's it like in South Mission Beach?
Guests are sure to enjoy their time checking out all that San Diego's South Mission Beach neighbourhood has to offer. Experience the best of South Mission Beach with a visit to Mission Beach and Mission Bay during your trip.
How many hotels are there in South Mission Beach?
If you're searching for places to stay in San Diego, Expedia has something to meet your needs with 319 South Mission Beach hotels and other accommodation options to choose from.
If I need to cancel my hotel reservation in South Mission Beach, will I receive a refund?
Yes! Most hotel reservations are fully refundable if you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before your check-in date. If you have a non-refundable reservation, you may still be able to cancel and receive a refund within a 24-hour period of your booking. Add dates, click "Search", then use the filter option "fully refundable" to get the best options available in South Mission Beach.
What is there to do in this San Diego neighbourhood?
Enjoy a stroll along the shore at Mission Beach, Mission and Pacific Beaches and South Mission Beach while you're in South Mission Beach. You could also plan a visit to Mission Bay or Belmont Park while you're in the neighbourhood. Golf Gardens Miniature Golf, Dog Beach and Bahia Point Beach are just a few of the places to visit in and around South Mission Beach. While you're out sightseeing in San Diego, make sure that you visit other sights such as Ocean Beach Athletic Area or Ocean Beach.