Southeastern Indiana Holidays

Book a Hotel + Flight or Car together to unlock savings

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Where to stay in Southeastern Indiana

Find the best Southeastern Indiana areas and neighborhoods for the activities you enjoy most. Learn more about Southeastern Indiana
The entrance to the Kentucky Science Center with a large circular structure in the foreground.

West Main Historic District

A noteworthy feature of West Main Historic District is its fantastic nightlife. While you're in town, be sure to stop and check out Frazier International History Museum and Louisville Slugger Museum.

Find hotels in West Main Historic District

Top hotels in Southeastern Indiana

Radisson Hotel Louisville North

Radisson Hotel Louisville North

3 out of 5
505 Marriott Drive Clarksville IN
Fully refundableReserve now, pay when you stay
The price is 1.835.549 ₫ per night from 30 Jul to 31 Jul
1.835.549 ₫
2.074.170 ₫ total
30 Jul - 31 Jul
includes taxes & fees
Radisson Hotel Louisville North
Derby Hotel & Suites

Derby Hotel & Suites

2 out of 5
505 K Marriot Dr Clarksville IN
Fully refundable
The price is 1.566.932 ₫ per night from 30 Jul to 31 Jul
1.566.932 ₫
1.770.633 ₫ total
30 Jul - 31 Jul
includes taxes & fees
6.6/10 (153 reviews)
"Not too good"

Reviewed on 28 Jul 2026

Derby Hotel & Suites
Big Splash Adventure Indoor Water Park & Resort

Big Splash Adventure Indoor Water Park & Resort

3.5 out of 5
8505 W State Road 56 French Lick IN
The price is 3.173.589 ₫ per night from 18 Aug to 19 Aug
3.173.589 ₫
3.941.590 ₫ total
18 Aug - 19 Aug
includes taxes & fees
Big Splash Adventure Indoor Water Park & Resort
See all 1,108 properties in Southeastern Indiana
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Stay near popular Southeastern Indiana attractions

A wall of wooden baseball bats organized by size and weight.

Louisville Slugger Museum

9.2/10 (2,299 reviews)
You can spend an afternoon studying the exhibits at Louisville Slugger Museum during your travels in Louisville. Amble around the area's riverfront or attend a sporting event.
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Frequently asked questions

How much does a Southeastern Indiana holiday package cost?
Our Southeastern Indiana holiday packages, which start from just , are an ideal way to save loads of cash. Pick and choose your preferred flights, hotels and rental cars to create a custom-built escape.
How do I get a cheap travel package to Southeastern Indiana?
If you love landing a bargain, bundle your bookings into a Southeastern Indiana holiday package. Whether you need flights, hotels, activities or rental cars, you can browse and book everything in one place. You'll have loads of choice at your fingertips too. Expedia has over 550 partner airlines and 1null000null000 hotel options throughout the world to choose from. Fly with who you want, stay wherever you like and save your hard-earned money — now that's the ideal escape!
Where should I stay in Southeastern Indiana?
You'll adore Louisville. Well-known attractions, such as Churchill Downs and Muhammad Ali Centre, will keep you entertained in this happening city.
What are the top hotels in Southeastern Indiana?
Galt House Hotel Trademark Collection by Wyndham and Radisson Hotel Louisville Jeffersonville know how to make their guests feel at home in Louisville. If you also plan to stay in Jeffersonville - Clarksville, have a look at Radisson Hotel Louisville Jeffersonville and JW Marriott Indianapolis. Both are top picks with travellers.
How far in advance should I book my Southeastern Indiana holiday?
It can be difficult to know when is the perfect time to book your Southeastern Indiana holiday. But usually the earlier you book, the more affordable the prices. In some cases, you can book your flights and hotels up to 12 months prior to your departure date. If you're thinking of a last-minute getaway, no need to fret! There are fabulous deals posted on Expedia every single day.
What does an Expedia Southeastern Indiana travel package include?
Packages include rental cars, flights and hotels, but you can mix and match them to create your perfect Southeastern Indiana holiday. You can also add on fun things like experiences and activities once you've made your booking. You're in the driver's seat! When you bundle your bookings with Expedia, you'll get access to deals you won't find anywhere else.
What should I know before booking a Southeastern Indiana travel package?
Whether it's adventure or relaxation you're craving, a Southeastern Indiana holiday package lets you organise your escape your way. Plus, you'll get access to great discounts just for combining your hotel with your rental car and flights. The more you bundle, the bigger the savings!
Can I choose my airline with a Southeastern Indiana Expedia holiday package?
Expedia has access to more than 550 partner airlines globally, so you definitely can. Just select your preferred carrier and craft your ideal Southeastern Indiana escape.
If I'm not able to travel, can I cancel my Southeastern Indiana holiday package?
Whether it's your hotel, flight or rental car, you can cancel or alter it. Booked your Southeastern Indiana holiday package in the last 24 hours? You may be able to make changes at no cost. For bookings made more than 24 hours ago, you may be charged a fee by your airline, hotel or car rental company. For further information, look up our Customer Service Portal. We'll help you each step of the way.