An aerial view of a town with industrial buildings, roads, and green areas.

Find hotels in St. Charles, MN from 1.560.118 ₫

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
12 Aug - 13 Aug
Tomorrow
13 Aug - 14 Aug
This weekend
14 Aug - 16 Aug
Next weekend
21 Aug - 23 Aug

Filter by

Star rating

Guest rating

Our top choices for St. Charles hotels

Budget
Reserve now, pay later
Hotel
Inn
Breakfast included

1. Hampton Inn Rochester-South

Hampton Inn Rochester-South
Rochester
United States
Lynne
2.462.173 ₫
2.834.576 ₫ total
includes taxes & fees
23 Aug - 24 Aug
Hampton Inn Rochester-South

2. La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S

La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S
Rochester
United States
Darrel
1.977.188 ₫
2.276.238 ₫ total
includes taxes & fees
16 Aug - 17 Aug
La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S

3. Comfort Inn & Suites Rochester South Mayo Clinic

Comfort Inn & Suites Rochester South Mayo Clinic
Rochester
United States
Anne
2.131.129 ₫
2.453.463 ₫ total
includes taxes & fees
30 Aug - 31 Aug
Comfort Inn & Suites Rochester South Mayo Clinic

4. AmericInn by Wyndham Rochester Near Mayo Clinic

AmericInn by Wyndham Rochester Near Mayo Clinic
Rochester
United States
Luis
1.969.738 ₫
2.267.661 ₫ total
includes taxes & fees
23 Aug - 24 Aug
AmericInn by Wyndham Rochester Near Mayo Clinic

5. Hyatt House Rochester/Mayo Clinic Area

Hyatt House Rochester/Mayo Clinic Area
Downtown Rochester
United States
Bridgett
4.151.490 ₫
4.779.403 ₫ total
includes taxes & fees
14 Aug - 15 Aug
Hyatt House Rochester/Mayo Clinic Area

6. Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area

Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area
Historic Southwest
United States
Brandolyn
2.981.755 ₫
3.432.746 ₫ total
includes taxes & fees
28 Aug - 29 Aug
Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area

7. Kahler Inn and Suites - Mayo Clinic Area

Kahler Inn and Suites - Mayo Clinic Area
Downtown Rochester
United States
Hafsa
3.188.592 ₫
3.671.063 ₫ total
includes taxes & fees
16 Aug - 17 Aug
Kahler Inn and Suites - Mayo Clinic Area

8. AmericInn by Wyndham Winona

AmericInn by Wyndham Winona
Winona
United States
Jacob
3.084.897 ₫
3.443.517 ₫ total
includes taxes & fees
13 Sept - 14 Sept
AmericInn by Wyndham Winona

9. Holiday Inn Express Rochester South - Mayo Area by IHG

Holiday Inn Express Rochester South - Mayo Area by IHG
Rochester
United States
Stephanie
2.509.056 ₫
2.888.549 ₫ total
includes taxes & fees
30 Aug - 31 Aug
Holiday Inn Express Rochester South - Mayo Area by IHG

10. Best Western Rochester Hotel Mayo Clinic Area/St. Mary's

Best Western Rochester Hotel Mayo Clinic Area/St. Mary's
Rochester
United States
Margita
2.455.646 ₫
2.827.061 ₫ total
includes taxes & fees
23 Aug - 24 Aug
Best Western Rochester Hotel Mayo Clinic Area/St. Mary's

11. Spark by Hilton Rochester South

Spark by Hilton Rochester South
Rochester
United States
Lijing
2.121.720 ₫
2.442.630 ₫ total
includes taxes & fees
30 Aug - 31 Aug
Spark by Hilton Rochester South

12. Microtel Inn & Suites by Wyndham Rochester North Mayo Clinic

Microtel Inn & Suites by Wyndham Rochester North Mayo Clinic
Rochester
United States
Siddhartha
1.866.110 ₫
2.148.360 ₫ total
includes taxes & fees
25 Aug - 26 Aug
Microtel Inn & Suites by Wyndham Rochester North Mayo Clinic

13. Med City Inn & Suites - Mayo Clinic Area

Med City Inn & Suites - Mayo Clinic Area
Kutzky Park
United States
Olivia
1.905.314 ₫
2.193.333 ₫ total
includes taxes & fees
29 Aug - 30 Aug
Med City Inn & Suites - Mayo Clinic Area

14. Brentwood Inn & Suites

Brentwood Inn & Suites
Downtown Rochester
United States
Bryan
3.263.750 ₫
3.757.490 ₫ total
includes taxes & fees
14 Aug - 15 Aug
Brentwood Inn & Suites

15. Aspen Suites

Aspen Suites
Rochester
United States
CASEY
3.704.778 ₫
4.478.665 ₫ total
includes taxes & fees
5 Sept - 6 Sept
Aspen Suites

16. Home2 Suites by Hilton Rochester Mayo Clinic Area

Home2 Suites by Hilton Rochester Mayo Clinic Area
Rochester
United States
Timothy
3.193.296 ₫
3.676.283 ₫ total
includes taxes & fees
4 Sept - 5 Sept
Home2 Suites by Hilton Rochester Mayo Clinic Area

17. Econo Lodge Mayo Clinic Area

Econo Lodge Mayo Clinic Area
Rochester
United States
Markus
1.836.577 ₫
2.114.360 ₫ total
includes taxes & fees
13 Sept - 14 Sept
Econo Lodge Mayo Clinic Area

18. Kahler Grand Hotel

Kahler Grand Hotel
Downtown Rochester
United States
Deminica
2.996.255 ₫
3.449.438 ₫ total
includes taxes & fees
8 Sept - 9 Sept
Kahler Grand Hotel

19. Holiday Inn Express & Suites Rochester – Mayo Clinic Area by IHG

Holiday Inn Express & Suites Rochester – Mayo Clinic Area by IHG
Kutzky Park
United States
Janet
2.744.280 ₫
3.159.353 ₫ total
includes taxes & fees
22 Aug - 23 Aug
Holiday Inn Express & Suites Rochester – Mayo Clinic Area by IHG

20. Hampton Inn & Suites Rochester-North

Hampton Inn & Suites Rochester-North
Rochester
United States
Albert
2.550.351 ₫
2.936.092 ₫ total
includes taxes & fees
4 Sept - 5 Sept
Hampton Inn & Suites Rochester-North
View all properties
Save an average of 15% on thousands of hotels when you're signed in

Learn more about St. Charles

St. Charles awaits: its natural setting and more!

See all hotels in St. Charles
An aerial view of a town with industrial buildings, roads, and green areas.

Top St. Charles Hotel Reviews

Brentwood Inn & Suites

Brentwood Inn & Suites

8/10 Good
"The bathroom fan in 238 is horribly loud. Needs changing out."
Belvel 1-night trip
Posted 1 hour ago
Brentwood Inn & Suites
Kahler Inn and Suites - Mayo Clinic Area

Kahler Inn and Suites - Mayo Clinic Area

8/10 Good
"Clean facility"
Mohamed 2-night trip
Posted 1 hour ago
Kahler Inn and Suites - Mayo Clinic Area
La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S

La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S

10/10 Excellent
"Late check in and early departure"
Merlyn 1-night trip
Posted 5 hours ago
La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S
Hampton Inn Rochester-South

Hampton Inn Rochester-South

10/10 Excellent
"Nice staff, clean room with good breakfast."
Lynne 2-night trip
Posted 10 hours ago
Hampton Inn Rochester-South
Express Suites Riverport Inn & Suites

Express Suites Riverport Inn & Suites

10/10 Excellent
"The connected restaurant was very good and easy"
Elizabeth 1-night trip
Posted 12 hours ago
Express Suites Riverport Inn & Suites
AmericInn by Wyndham Rochester Near Mayo Clinic

AmericInn by Wyndham Rochester Near Mayo Clinic

8/10 Good
"Very clean. Comfortable bed. Excellent restaurant"
Tony 1-night trip
Posted 1 day ago
AmericInn by Wyndham Rochester Near Mayo Clinic
Super 8 by Wyndham Rochester Mayo Clinic Area

Super 8 by Wyndham Rochester Mayo Clinic Area

10/10 Excellent
"The room is very nice and clean"
Okong 1-night trip
Posted 2 days ago
Super 8 by Wyndham Rochester Mayo Clinic Area
Staybridge Suites Rochester - Mayo Clinic Area by IHG

Staybridge Suites Rochester - Mayo Clinic Area by IHG

8/10 Good
"Office staff, particularly Affinity, wss extremely helpful! Major drawback was parking was oversold which seriously inconvenience guests who went out for dinner."
Kalvin 6-night trip
Posted 3 days ago
Staybridge Suites Rochester - Mayo Clinic Area by IHG
Big River Escape Riverside Cabins

Big River Escape Riverside Cabins

10/10 Excellent
"Great experience. Traveling with my husband to visit the area and do hikes. Nice location and cozy cute cabins! Owner is super helpful and kind. Minor hiccup at check-in due to booking through Expedia - Expedia doesn't share any info with the owner of the property and the email for my self check-in wasn't sent. I called the owner and he called right back after a few minutes and was able to give me all the instructions I needed. He even gave me some hiking recommendations. Later, the water wasn't getting hot in our cabin. I texted the owner and he came to check things out right away. He informed us that sadly, the water heater was going to need repairs. He upgraded us to another cabin that was actually bigger and very nice - the one we were in was also so cozy and lovely. Thankfully, our stay was uneventful (in the best way) from there on out! Cabins are very clean, cozy and have everything you need to cook food if you choose! Not far away from nice hikes in Winona or Alma. Oh and it's near the water too with a dock if you're into that. 😁 Owner is extremely kind, accommodating and hospitable. Highly recommend."
Eliana 2-night trip
Posted 4 months ago
Big River Escape Riverside Cabins

More cheap stays in St. Charles

Super 8 by Wyndham Rochester Mayo Clinic Area

Super 8 by Wyndham Rochester Mayo Clinic Area

106 SE 21st Street Rochester MN
1.355.152 ₫
1.560.118 ₫ total
30 Aug - 31 Aug
includes taxes & fees
7.8/10 Good! (1,000 reviews)
Super 8 by Wyndham Rochester Mayo Clinic Area
Super 8 by Wyndham Winona MN

Super 8 by Wyndham Winona MN

1025 Sugar Loaf Rd Winona MN
1.618.820 ₫
1.839.384 ₫ total
13 Sept - 14 Sept
includes taxes & fees
Super 8 by Wyndham Winona MN
Med City Inn & Suites - Mayo Clinic Area

Med City Inn & Suites - Mayo Clinic Area

435 16th Ave Nw Rochester MN
1.905.314 ₫
2.193.333 ₫ total
29 Aug - 30 Aug
includes taxes & fees
Med City Inn & Suites - Mayo Clinic Area
Best Western Rochester Hotel Mayo Clinic Area/St. Mary's

Best Western Rochester Hotel Mayo Clinic Area/St. Mary's

1517 16th St Sw Rochester MN
2.455.646 ₫
2.827.061 ₫ total
23 Aug - 24 Aug
includes taxes & fees
Best Western Rochester Hotel Mayo Clinic Area/St. Mary's
Hampton Inn Rochester-South

Hampton Inn Rochester-South

1755 S Broadway Rochester MN
2.462.173 ₫
2.834.576 ₫ total
23 Aug - 24 Aug
includes taxes & fees
9/10 Wonderful! (1,002 reviews)
Hampton Inn Rochester-South
Brentwood Inn & Suites

Brentwood Inn & Suites

123 Fourth Ave. NW Rochester MN
3.263.750 ₫
3.757.490 ₫ total
14 Aug - 15 Aug
includes taxes & fees
8.8/10 Excellent! (1,003 reviews)
Brentwood Inn & Suites

Hotels in St. Charles with star rating

Frequently asked questions

What's the weather like in St. Charles?
The hottest months are usually July and August, with an average temperature of 19°C, while the coldest months are January and February, with an average of -6°C. The snowiest months in St. Charles are January, March, February and April, with each month seeing an average of 20 cm of snowfall.

Explore a world of travel with Expedia