Search Hotels Near UnityPoint Health St. Luke's, Sioux City

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Our top choices for UnityPoint Health St. Luke's hotels

Restaurant
Hard Rock Hotel & Casino Sioux City

Hard Rock Hotel & Casino Sioux City

Hard Rock Hotel & Casino Sioux City
4.0 star property
2.9 km from UnityPoint Health St. Luke's
9.2 out of 10, Wonderful, (1001)
"Rooms are very nice clean modern, adult beverages complimentary at check-in everything was very good"
United States
Kathryn
Hard Rock Hotel & Casino Sioux City
View from property
The Warrior Hotel, Autograph Collection

The Warrior Hotel, Autograph Collection

The Warrior Hotel, Autograph Collection
5.0 star property
2.6 km from UnityPoint Health St. Luke's
9.0 out of 10, Wonderful, (513)
"Love everything about this hotel "
United States
Amy
The price is 2.580.438 ₫
2.937.777 ₫ total
includes taxes & fees
27 Dec - 28 Dec
The Warrior Hotel, Autograph Collection
Restaurant
Courtyard by Marriott Sioux City Downtown/Convention Center

Courtyard by Marriott Sioux City Downtown/Convention Center

Courtyard by Marriott Sioux City Downtown/Convention Center
3.0 star property
2.9 km from UnityPoint Health St. Luke's
9.0 out of 10, Wonderful, (608)
"Lovely staff and beautiful location!!! Rooms are spacious and clean. Highly recommend. "
United States
Dawn
The price is 2.439.567 ₫
2.732.315 ₫ total
includes taxes & fees
27 Dec - 28 Dec
Courtyard by Marriott Sioux City Downtown/Convention Center
Superior Suite, 1 King Bed with Sofa bed, Hot Tub | Living area | 37-inch flat-screen TV with cable channels, TV
Stoney Creek Hotel Sioux City

Stoney Creek Hotel Sioux City

Stoney Creek Hotel Sioux City
2.5 star property
3 km from UnityPoint Health St. Luke's
8.8 out of 10, Excellent, (2378)
"Great stay!"
United States
Chad
Stoney Creek Hotel Sioux City
Daily buffet breakfast for a fee
DoubleTree by Hilton Sioux City

DoubleTree by Hilton Sioux City

DoubleTree by Hilton Sioux City
4.0 star property
3.3 km from UnityPoint Health St. Luke's
9.4 out of 10, Exceptional, (124)
"Clean room and staff was great "
United States
timothy
The price is 2.350.042 ₫
2.675.476 ₫ total
includes taxes & fees
8 Jan - 9 Jan 2026
DoubleTree by Hilton Sioux City
Exterior
avid hotel Sioux City - Downtown by IHG

avid hotel Sioux City - Downtown by IHG

avid hotel Sioux City - Downtown by IHG
2.5 star property
3.2 km from UnityPoint Health St. Luke's
8.6 out of 10, Excellent, (433)
"Nice hotel "
United States
Michelle
The price is 2.080.149 ₫
2.368.210 ₫ total
includes taxes & fees
18 Jan - 19 Jan 2026
avid hotel Sioux City - Downtown by IHG
Lobby
Hilton Garden Inn Sioux City Riverfront

Hilton Garden Inn Sioux City Riverfront

Hilton Garden Inn Sioux City Riverfront
3.0 star property
3.6 km from UnityPoint Health St. Luke's
8.8 out of 10, Excellent, (1000)
"Staff was super nice and accommodating. Room was great, pool was warm and wonderful in freezing December. Restaurant with hotel has great food. Awesome views of the river."
United States
Chea
The price is 2.137.551 ₫
2.433.557 ₫ total
includes taxes & fees
9 Jan - 10 Jan 2026
Hilton Garden Inn Sioux City Riverfront
Reception
South Sioux City Marriott Riverfront

South Sioux City Marriott Riverfront

South Sioux City Marriott Riverfront
3.0 star property
3.8 km from UnityPoint Health St. Luke's
8.8 out of 10, Excellent, (1000)
"Great staff, clean, reasonably priced. Will stay again!"
United States
Robert
The price is 2.817.417 ₫
3.155.507 ₫ total
includes taxes & fees
5 Jan - 6 Jan 2026
South Sioux City Marriott Riverfront
Exterior
Holiday Inn Express & Suites Sioux City North-Event Center by IHG

Holiday Inn Express & Suites Sioux City North-Event Center by IHG

Holiday Inn Express & Suites Sioux City North-Event Center by IHG
2.5 star property
7 km from UnityPoint Health St. Luke's
9.4 out of 10, Exceptional, (750)
"Easy check-in, quiet accommodations, good power in the shower."
United States
Rick
The price is 2.264.638 ₫
2.562.464 ₫ total
includes taxes & fees
4 Jan - 5 Jan 2026
Holiday Inn Express & Suites Sioux City North-Event Center by IHG
Business centre
Days Inn by Wyndham North Sioux City

Days Inn by Wyndham North Sioux City

Days Inn by Wyndham North Sioux City
2.0 star property
7.8 km from UnityPoint Health St. Luke's
6.6 out of 10, (595)
"love this place my favorite place in town had a great price"
United States
Bryan
The price is 1.509.556 ₫
1.640.888 ₫ total
includes taxes & fees
18 Jan - 19 Jan 2026
Days Inn by Wyndham North Sioux City
Reception
Motel 6 North Sioux City, SD – I-29 North

Motel 6 North Sioux City, SD – I-29 North

Motel 6 North Sioux City, SD – I-29 North
2.0 star property
7.9 km from UnityPoint Health St. Luke's
6.6 out of 10, (369)
"Great room and pet friendly! Does not charge for pets!"
United States
Pam
The price is 1.711.515 ₫
1.860.417 ₫ total
includes taxes & fees
25 Dec - 26 Dec
Motel 6 North Sioux City, SD – I-29 North
Exterior
Super 8 by Wyndham Sioux City/Morningside Area

Super 8 by Wyndham Sioux City/Morningside Area

Super 8 by Wyndham Sioux City/Morningside Area
2.0 star property
6.3 km from UnityPoint Health St. Luke's
6.2 out of 10, (839)
"Gross hotel staff gave me a free day then canceled it mid day "
United States
Micah
The price is 1.579.980 ₫
1.769.578 ₫ total
includes taxes & fees
4 Jan - 5 Jan 2026
Super 8 by Wyndham Sioux City/Morningside Area
Free buffet breakfast
Quality Inn & Suites Sioux City Southeast

Quality Inn & Suites Sioux City Southeast

Quality Inn & Suites Sioux City Southeast
2.5 star property
10.2 km from UnityPoint Health St. Luke's
6.6 out of 10, (564)
"Especially liked the handicapped parking next to the front entrance!"
United States
Rachel
The price is 1.797.354 ₫
2.013.037 ₫ total
includes taxes & fees
18 Jan - 19 Jan 2026
Quality Inn & Suites Sioux City Southeast
Exterior
Country Inn & Suites by Radisson, Dakota Dunes, SD

Country Inn & Suites by Radisson, Dakota Dunes, SD

Country Inn & Suites by Radisson, Dakota Dunes, SD
3.0 star property
7.6 km from UnityPoint Health St. Luke's
8.8 out of 10, Excellent, (1001)
"Fast check in, clean, decent coffee"
Canada
Robert
The price is 2.293.957 ₫
2.543.925 ₫ total
includes taxes & fees
13 Jan - 14 Jan 2026
Country Inn & Suites by Radisson, Dakota Dunes, SD
Indoor pool
Hampton Inn North Sioux City

Hampton Inn North Sioux City

Hampton Inn North Sioux City
2.5 star property
7.9 km from UnityPoint Health St. Luke's
9.0 out of 10, Wonderful, (826)
"close to Interstate"
United States
Judith
The price is 2.245.678 ₫
2.481.331 ₫ total
includes taxes & fees
28 Dec - 29 Dec
Hampton Inn North Sioux City
Exterior
Cottonwood Inn and Conference Center

Cottonwood Inn and Conference Center

Cottonwood Inn and Conference Center
2.5 star property
8.2 km from UnityPoint Health St. Luke's
8.4 out of 10, Very good, (1002)
"Great place super friendly staff!!"
United States
Janelle M
The price is 1.535.361 ₫
1.874.241 ₫ total
includes taxes & fees
25 Dec - 26 Dec
Cottonwood Inn and Conference Center
Lobby
Rodeway Inn Sergeant Bluff - Sioux City

Rodeway Inn Sergeant Bluff - Sioux City

Rodeway Inn Sergeant Bluff - Sioux City
2.0 star property
13.9 km from UnityPoint Health St. Luke's
5.8 out of 10, (205)
"I never was available to check in lobby door lock and mobile open the door I was ringing for over 45 minutes "
United States
Adalberto
The price is 1.184.895 ₫
1.327.082 ₫ total
includes taxes & fees
6 Jan - 7 Jan 2026
Rodeway Inn Sergeant Bluff - Sioux City
Exterior
Staybridge Suites Sioux City Southeast by IHG

Staybridge Suites Sioux City Southeast by IHG

Staybridge Suites Sioux City Southeast by IHG
3.0 star property
10 km from UnityPoint Health St. Luke's
9.4 out of 10, Exceptional, (191)
"Rooms were great, spacious and comfortable."
United States
Jenna
The price is 2.580.438 ₫
2.890.091 ₫ total
includes taxes & fees
8 Jan - 9 Jan 2026
Staybridge Suites Sioux City Southeast by IHG
Exterior
Holiday Inn Express & Suites Sioux City - Southern Hills by IHG

Holiday Inn Express & Suites Sioux City - Southern Hills by IHG

Holiday Inn Express & Suites Sioux City - Southern Hills by IHG
2.5 star property
10 km from UnityPoint Health St. Luke's
9.4 out of 10, Exceptional, (510)
"Robbie and team did an excellent job ensuring everything was ready for my mom. "
United States
Charles
The price is 2.922.741 ₫
3.321.656 ₫ total
includes taxes & fees
18 Jan - 19 Jan 2026
Holiday Inn Express & Suites Sioux City - Southern Hills by IHG
Exterior
Hampton Inn & Suites Sioux City South

Hampton Inn & Suites Sioux City South

Hampton Inn & Suites Sioux City South
2.5 star property
10 km from UnityPoint Health St. Luke's
9.2 out of 10, Wonderful, (1001)
"It was a great stay"
United States
Jamie
The price is 2.396.830 ₫
2.728.743 ₫ total
includes taxes & fees
4 Jan - 5 Jan 2026
Hampton Inn & Suites Sioux City South
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top UnityPoint Health St. Luke's Hotel Reviews

DoubleTree by Hilton Sioux City

DoubleTree by Hilton Sioux City

10/10 Excellent
"Bar was nice addition "
Brad 3-night trip
Posted 2 weeks ago
DoubleTree by Hilton Sioux City

Hotels near other UnityPoint Health St. Luke's attractions

Saint Luke's College

Walk around the campus at Saint Luke's College during your visit to Sioux City. Discover the live music and casinos in this family-friendly area.
See properties

Grandview Park

Grandview Park is just one of the places to see in Sioux City, so why not enjoy the other things to explore during your travels? Experience the live music or attend a sporting event in this family-friendly area.
See properties

Frequently asked questions

What's the area like around UnityPoint Health St. Luke's?
UnityPoint Health St. Luke's is located in Sioux City. Travellers like this family-friendly area for its sporting events and live music. You'll find 61 hotels and other accommodations within a few miles for a convenient home base.
How many hotels will I find close to UnityPoint Health St. Luke's?
Expedia has 61 hotels and other accommodation options a few miles from UnityPoint Health St. Luke's.
If I need to cancel the hotel reservation for my stay near UnityPoint Health St. Luke's, will I receive a refund?
Yes! You'll find that most hotel room reservations are refundable if you cancel before the hotel's cancellation deadline, which is usually within 24-48 hours of your arrival date. If you booked a non-refundable reservation, you may still be able to cancel and receive a refund within 24 hours of booking. Enter your dates, click on "Search", then use the filter option "fully refundable" to view the best deals available near UnityPoint Health St. Luke's.
What can I see and do near UnityPoint Health St. Luke's?
You'll want to browse the collections at Sioux City Public Museum, The Sioux City Lewis and Clark Interpretive Center and Sergeant Floyd River Museum and Welcome Center. You can watch performances at Orpheum Theatre, Briar Cliff University Theater and Lamb Productions Theatre if you're interested in local theatre. Enjoy the outdoors at Scenic Park, Jeffrey Dibble Sports Complex or Klasey Park.