Compare and book 4 Star hotels in Florida Keys, United States of America

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Check availability on Florida Keys 4 Star Hotels

Our top choices for Florida Keys 4-star hotels

3 restaurants, breakfast, lunch, dinner served; American cuisine

Reefhouse Resort & Marina

Reefhouse Resort & Marina
4.5 star property
Key Largo
9.2 out of 10, Wonderful, (1,403 reviews)
"Clean rooms, nice staff, great beach area."
United States
Brittany
The price is 7.874.763 ₫
9.912.720 ₫ total
includes taxes & fees
22 Apr - 23 Apr
Reefhouse Resort & Marina
Property grounds

Baker's Cay Resort Key Largo, Curio Collection by Hilton

Baker's Cay Resort Key Largo, Curio Collection by Hilton
4.0 star property
Key Largo
8.6 out of 10, Excellent, (1,037 reviews)
"The resort was beautiful. We really enjoyed our time there."
United States
Jessica
The price is 9.265.182 ₫
11.875.343 ₫ total
includes taxes & fees
5 May - 6 May
Baker's Cay Resort Key Largo, Curio Collection by Hilton
Alligator Reef Oceanfront Room King Lanai with Queen Sofabed | View from room

Amara Cay Resort

Amara Cay Resort
4.0 star property
Matecumbe
8.8 out of 10, Excellent, (1,263 reviews)
"Great staff, lovely location, great Tiki Bar"
United States
David
The price is 7.982.087 ₫
10.905.872 ₫ total
includes taxes & fees
4 May - 5 May
Amara Cay Resort
5 outdoor pools, pool cabanas (surcharge), pool umbrellas

Hawks Cay Resort

Hawks Cay Resort
4.0 star property
Marathon
8.0 out of 10, Very good, (1,002 reviews)
"Great property!"
United States
Andrei
The price is 8.171.364 ₫
11.033.283 ₫ total
includes taxes & fees
17 May - 18 May
Hawks Cay Resort
Exterior

Islander Resort

Islander Resort
4.0 star property
Matecumbe
9.2 out of 10, Wonderful, (1,001 reviews)
"Beautiful place to stay! "
United States
DeShawn
The price is 5.056.896 ₫
7.466.823 ₫ total
includes taxes & fees
17 May - 18 May
Islander Resort
2 bars/lounges, poolside bar

Faro Blanco Resort Marathon Florida Keys, Curio by Hilton

Faro Blanco Resort Marathon Florida Keys, Curio by Hilton
4.0 star property
Marathon
8.8 out of 10, Excellent, (1,167 reviews)
"Beautiful hotel "
United States
Brooke
The price is 6.457.306 ₫
8.255.530 ₫ total
includes taxes & fees
3 May - 4 May
Faro Blanco Resort Marathon Florida Keys, Curio by Hilton
Exterior

Playa Largo Resort & Spa, Autograph Collection

Playa Largo Resort & Spa, Autograph Collection
4.5 star property
Rock Harbor
8.8 out of 10, Excellent, (1,002 reviews)
"Overall wonderful resort and great location. "
United States
Kristie Howle
The price is 9.454.983 ₫
12.088.814 ₫ total
includes taxes & fees
6 May - 7 May
Playa Largo Resort & Spa, Autograph Collection
In-room safe, individually decorated, individually furnished

Three Waters Resort and Marina, Islamorada, a Tribute Portfolio Resort

Three Waters Resort and Marina, Islamorada, a Tribute Portfolio Resort
4.0 star property
Islamorada
9.0 out of 10, Wonderful, (184 reviews)
"Very, very good architectural design and construction. And a well-maintained facility."
United States
roy steven
The price is 7.611.682 ₫
10.311.590 ₫ total
includes taxes & fees
4 May - 5 May
Three Waters Resort and Marina, Islamorada, a Tribute Portfolio Resort
Suite, 1 King Bed with Sofa bed, Ocean View | Egyptian cotton sheets, premium bedding, pillow-top beds, in-room safe

La Siesta Resort & Villas

La Siesta Resort & Villas
4.0 star property
Matecumbe
8.6 out of 10, Excellent, (1,002 reviews)
"We had a enjoyable stay here and would come back again if we were ever in the area. "
United States
angela
The price is 6.026.564 ₫
8.705.910 ₫ total
includes taxes & fees
29 Apr - 30 Apr
La Siesta Resort & Villas
3 outdoor pools, pool loungers

Tranquility Bay Beachfront Hotel and Resort

Tranquility Bay Beachfront Hotel and Resort
4.0 star property
Marathon
8.8 out of 10, Excellent, (1,000 reviews)
"Amazing resort "
United States
Joy
The price is 7.798.682 ₫
10.491.018 ₫ total
includes taxes & fees
3 May - 4 May
Tranquility Bay Beachfront Hotel and Resort
5 outdoor pools, pool cabanas (surcharge), pool umbrellas

Villas At Hawks Cay Resort

Villas At Hawks Cay Resort
4.0 star property
Marathon
8.2 out of 10, Very good, (192 reviews)
"We had a great stay."
United States
Elise
The price is 17.990.805 ₫
21.869.719 ₫ total
includes taxes & fees
2 May - 3 May
Villas At Hawks Cay Resort
Balcony view

Grassy Flats Resort & Beach Club

Grassy Flats Resort & Beach Club
4.0 star property
Marathon
9.4 out of 10, Exceptional, (432 reviews)
"Yes the view was nice, the hotel staff was nice and the room was clean"
United States
DEBORAH LEE
The price is 6.065.509 ₫
8.087.922 ₫ total
includes taxes & fees
18 May - 19 May
Grassy Flats Resort & Beach Club
On the beach, sun-loungers, beach umbrellas, beach towels

The Islands of Islamorada

The Islands of Islamorada
4.0 star property
Matecumbe
9.8 out of 10, Exceptional, (74 reviews)
"Beautiful accommodations and location, very clean, many activities available at resort"
United States
Janet
The price is 17.722.086 ₫
21.389.229 ₫ total
includes taxes & fees
20 Apr - 21 Apr
The Islands of Islamorada
Exterior

The Reef at Marathon, Florida Keys

The Reef at Marathon, Florida Keys
4.0 star property
Marathon
9.2 out of 10, Wonderful, (24 reviews)
"Absolutely LOVED this place!! Affordable rates first of all, clean! Arrived late for check in and it was a quick smooth process, friendly staff. Definitely going back! "
United States
Angie
The Reef at Marathon, Florida Keys
Exterior

Marlin Bay Resort & Marina

Marlin Bay Resort & Marina
4.5 star property
Marathon
10.0 out of 10, Exceptional, (2 reviews)
"Wonderful vacation!"
United States
Chardell
Marlin Bay Resort & Marina
Luxury Villa, 3 Bedrooms, Balcony, Overwater | Terrace/patio

Waterfront Luxury Villa

Waterfront Luxury Villa
4.0 star property
Marathon Shores
Waterfront Luxury Villa
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Explore similar 5-star hotels

Many 5-star hotels have the same amenities as 4-star hotels. See all 5-star hotels in Florida Keys.
Cheeca Lodge & Spa

Cheeca Lodge & Spa

81801 Overseas Highway, Mile Marker 82 Islamorada FL
The price is 7.875.062 ₫ per night from 3 May to 4 May
7.875.062 ₫
10.785.674 ₫ total
3 May - 4 May
includes taxes & fees
9.2/10 Wonderful! (1,314 reviews)
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Florida Keys

Snorkel crystal-clear waters teeming with colourful fish, then feast on fresh-caught lobster at a laid-back waterfront shack. Drive the scenic Overseas Highway, stopping at Key West's Ernest Hemingway Home and Dry Tortugas National Park for island adventures.

See all hotels in Florida Keys

Top Florida Keys Hotel Reviews

Hawks Cay Resort

Hawks Cay Resort

10/10 Excellent
"We absolutely loved it here. Family-friendly, beautiful, and fun. Would highly recommend. "
Kellirose 5-night trip
Posted 12 hours ago
Hawks Cay Resort

Frequently asked questions

What are the best 4-star hotels in Florida Keys?
You'll discover a variety of 4-star hotels in Florida Keys, including in Key Largo. Playa Largo Resort & Spa, Autograph Collection is a customer favourite in this city that offers a tennis court and a sauna. Another stay that rates highly with travellers is Bakers Cay Resort Key Largo, Curio Collection by Hilton. Dining romance packages and private picnic options help make it their preferred choice.
How much does it cost to stay in a 4-star hotel in Florida Keys?
To find a 4-star hotel in Florida Keys that fits your budget, take advantage of Expedia's handy search filters. Take a look at the availability during your holiday dates and use our pricing filter to set your maximum rate. You can also sort your results by the most affordable retreat first.

  • Search for the lowest price from 10.785.674 ₫

What's the difference between 5-star and 4-star hotels in Florida Keys?
Offering a welcoming traveller experience and upmarket décor, 4-star hotels are an excellent option for your Florida Keys getaway. These types of accommodation generally feature loads of useful amenities that make it easy to unpack and relax — think pillowtop mattresses, pools and restaurants. Or live the high life at a 5-star hotel designed to spoil you with high-end perks and amenities. Concierge assistance, premium toiletries and fine dining are typically included at these deluxe properties.