A beach with palm trees, people relaxing on chairs, and colorful kayaks.

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Check availability on Florida Keys 4 Star Hotels

Tonight
31 Aug - 1 Sep
Tomorrow
1 Sep - 2 Sep
This weekend
4 Sep - 6 Sep
Next weekend
11 Sep - 13 Sep

Our top choices for Florida Keys 4-star hotels

A pool area with lounge chairs and umbrellas, surrounded by palm trees.
A spacious lobby with high ceilings, large windows, and a central coffee table surrounded by sofas and chairs.
A pathway leading to a pool area with palm trees and a sunset view.
A modern living room with a balcony overlooking the sea, furnished with a sofa, chairs, and a dining table.

1. Hawks Cay Resort

Hawks Cay Resort
Marathon
United States
Leonard
4.837.208 ₫
7.446.736 ₫ total
includes taxes & fees
13 Sept - 14 Sept
Hawks Cay Resort
A hammock on a sandy beach with a view of the sea and a tree overhead.
A spacious interior with a high ceiling, large windows, and a central chandelier.
A table with a glass pitcher, a glass with a slice of lime, and a plate with raspberries and a sprig of rosemary.
A spacious dining area with high ceilings, wicker furniture, and large windows.

2. Baker's Cay Resort Key Largo, Curio Collection by Hilton

Baker's Cay Resort Key Largo, Curio Collection by Hilton
Key Largo
United States
Vianney
6.179.964 ₫
8.390.139 ₫ total
includes taxes & fees
28 Sept - 29 Sept
Baker's Cay Resort Key Largo, Curio Collection by Hilton
A wooden deck with two lounge chairs, a table with two glasses of champagne and red roses, and a view of the beach and ocean.
A hotel room with a bed, a sofa, a coffee table, a desk with a lamp, and a view of the ocean.
An aerial view of a resort with a swimming pool, palm trees, and a dock.
A resort pool with palm trees, beach chairs, and umbrellas.

3. Amara Cay Resort

Amara Cay Resort
Matecumbe
United States
David A
3.854.981 ₫
6.243.938 ₫ total
includes taxes & fees
3 Sept - 4 Sept
Amara Cay Resort
A dining area with tables set for two, overlooking a beach with palm trees and a sunset view.
A beach with thatched umbrellas, palm trees, and blue lounge chairs.
A poolside area with blue chairs and a thatched-roof structure.
A spacious living room with large windows, comfortable seating, and decorative plants.

4. Reefhouse Resort & Marina

Reefhouse Resort & Marina
Key Largo
United States
Matt
5.711.082 ₫
7.468.218 ₫ total
includes taxes & fees
2 Sept - 3 Sept
Reefhouse Resort & Marina
An aerial view of a resort with two swimming pools surrounded by palm trees and sun loungers.
A bar area with a wooden counter, bar stools, and potted plants.
A paved pathway leading to a beach with palm trees and a view of the ocean.
A beachside patio with wooden furniture, a thatched roof, and a view of the ocean.

5. Islander Resort

Islander Resort
Matecumbe
United States
Sonia
6.363.032 ₫
8.918.676 ₫ total
includes taxes & fees
22 Sept - 23 Sept
Islander Resort
An aerial view of a resort with a large pool, palm trees, and a beach.
A restaurant with wooden tables and chairs, a bar area, and a view of the sea.
A beachside patio with lounge chairs, a table, and a view of the ocean.
A beach with clear water, a wooden pier, and lounge chairs under a tree.

6. Playa Largo Resort & Spa, Autograph Collection

Playa Largo Resort & Spa, Autograph Collection
Rock Harbor
United States
Rachel
6.649.890 ₫
8.918.806 ₫ total
includes taxes & fees
14 Sept - 15 Sept
Playa Largo Resort & Spa, Autograph Collection
A balcony with wicker chairs, a small table with drinks, and a view of the beach and ocean.
A beach with palm trees, a clear blue sky, and a calm sea.
A resort with a pool, beach, and ocean view.
A coastal resort with a beach, a swimming pool, and multiple buildings.

7. Three Waters Resort and Marina, Islamorada, a Tribute Portfolio Resort

Three Waters Resort and Marina, Islamorada, a Tribute Portfolio Resort
Islamorada
United States
Ana
4.568.165 ₫
7.045.978 ₫ total
includes taxes & fees
9 Sept - 10 Sept
Three Waters Resort and Marina, Islamorada, a Tribute Portfolio Resort
A swimming pool surrounded by palm trees and lounge chairs.
A wooden deck with blue chairs overlooking a beach with palm trees and the ocean.
An aerial view of a resort with a central swimming pool, surrounded by lush greenery and palm trees, with a view of the ocean.
A spacious living room with a wooden coffee table, a striped sofa, and a television on a wooden cabinet.

8. Tranquility Bay Beachfront Hotel and Resort

Tranquility Bay Beachfront Hotel and Resort
Marathon
United Kingdom
Stuart
4.986.114 ₫
7.278.892 ₫ total
includes taxes & fees
21 Sept - 22 Sept
Tranquility Bay Beachfront Hotel and Resort
A marina with boats docked, a lighthouse, and a resort with outdoor seating.
An outdoor dining area with tables and chairs, a pool, and a view of the sea and boats.
A room with two sofas, a round coffee table, and a small side table with a vase.
A bar area with a long counter, multiple bar stools, and a view of the marina with boats and palm trees.

9. Faro Blanco Resort Marathon Florida Keys, Curio by Hilton

Faro Blanco Resort Marathon Florida Keys, Curio by Hilton
Marathon
Canada
Patricia
3.827.729 ₫
5.287.510 ₫ total
includes taxes & fees
7 Sept - 8 Sept
Faro Blanco Resort Marathon Florida Keys, Curio by Hilton
A row of beachside cottages with colorful exteriors, each with a beach chair and umbrella.
A resort with a pool surrounded by palm trees and a view of the ocean.
A beach resort with palm trees, a thatched hut, and a purple building with a window.
A beach with colorful buildings, kayaks, and lounge chairs.

10. La Siesta Resort & Villas

La Siesta Resort & Villas
Matecumbe
United States
Brianne
3.854.390 ₫
6.242.981 ₫ total
includes taxes & fees
3 Sept - 4 Sept
La Siesta Resort & Villas
A resort pool with palm trees and lounge chairs, surrounded by a beachfront.
A modern living room with a sofa, chairs, a dining table, a TV, and a view of the ocean.
A resort with a large pool surrounded by lounge chairs, a beach area, and a building with multiple floors.
A modern kitchen with white cabinetry, a stainless steel oven, and a large island with a bowl of fruit.

11. Villas At Hawks Cay Resort

Villas At Hawks Cay Resort
Marathon
United States
Don
9.882.046 ₫
12.730.891 ₫ total
includes taxes & fees
13 Sept - 14 Sept
Villas At Hawks Cay Resort
A wooden deck with a pool and chairs overlooking a beach with palm trees.
A pool area with palm trees and a view of the ocean.
A bar area with stools, a counter, and hanging lanterns.
A hotel room with a sofa, a desk, a chair, a TV, and a balcony with curtains.

12. Grassy Flats Resort & Beach Club

Grassy Flats Resort & Beach Club
Marathon
United States
Tiffany
3.762.692 ₫
5.484.772 ₫ total
includes taxes & fees
29 Sept - 30 Sept
Grassy Flats Resort & Beach Club
A balcony with a wooden table, two chairs, and a view of the ocean and palm trees.
A beachside patio with a thatched roof, two lounge chairs, and a view of the ocean.
A resort with multiple white buildings, each featuring balconies and surrounded by lush greenery and palm trees.
A pool area with clear blue water, white lounge chairs, and palm trees.

13. The Islands of Islamorada

The Islands of Islamorada
Matecumbe
United States
Christian
9.388.080 ₫
12.186.902 ₫ total
includes taxes & fees
2 Sept - 3 Sept
The Islands of Islamorada
A large hotel with a pool, multiple balconies, and palm trees.
A beachside wedding setup with wicker chairs and a white canopy, palm trees, and a sunset view.
A beach with clear water and gentle waves.
A large, two-story hotel with a swimming pool in front.

14. Marlin Bay Resort & Marina

Marlin Bay Resort & Marina
Marathon
United States
Chardell
Marlin Bay Resort & Marina
A covered outdoor area with a wooden deck, white railings, and a view of the ocean.
An aerial view of a coastal resort with multiple buildings, a marina, and clear blue waters.
A resort with multiple buildings, a large central pool, and a view of the ocean.
A swimming pool with lounge chairs and palm trees.

15. Waterfront Luxury Villa

Waterfront Luxury Villa
Marathon Shores
Waterfront Luxury Villa
A beach with clear turquoise water, a wooden pier, and a rocky shoreline.
A modern kitchen with white cabinets, a microwave, and a dishwasher. There are three bar stools and a large window overlooking the ocean.
A modern kitchen with a central island, bar stools, and a ceiling fan.

16. Florida Keys Getaway w/ Stunning Ocean Views

Florida Keys Getaway w/ Stunning Ocean Views
Long Key
Florida Keys Getaway w/ Stunning Ocean Views
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Explore similar 5-star hotels

Many 5-star hotels have the same amenities as 4-star hotels. See all 5-star hotels in Florida Keys.
Cheeca Lodge & Spa

Cheeca Lodge & Spa

81801 Overseas Highway, Mile Marker 82 Islamorada FL
3.885.026 ₫
6.277.446 ₫ total
15 Sept - 16 Sept
includes taxes & fees
9.2/10 Wonderful! (1,422 reviews)
Cheeca Lodge & Spa
Isla Bella Beach Resort & Spa

Isla Bella Beach Resort & Spa

1 Knights Key Boulevard Marathon FL
5.139.974 ₫
7.334.634 ₫ total
2 Sept - 3 Sept
includes taxes & fees
9.2/10 Wonderful! (1,263 reviews)
Isla Bella Beach Resort & Spa
Still don't see what you're looking for?
See all properties in Florida Keys.
You can also use these popular filters to refine your search.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Florida Keys

Snorkel crystal-clear waters teeming with colourful fish, then feast on fresh-caught lobster at a laid-back waterfront shack. Drive the scenic Overseas Highway, stopping at Key West's Ernest Hemingway Home and Dry Tortugas National Park for island adventures.

See all hotels in Florida Keys
A beach with palm trees, people relaxing on chairs, and colorful kayaks.

Top Florida Keys Hotel Reviews

Baker's Cay Resort Key Largo, Curio Collection by Hilton

Baker's Cay Resort Key Largo, Curio Collection by Hilton

10/10 Excellent
"Nous n avons pas pris l option petit dej . Le parking devait être inclus mais il nous a été facturé ."
marc 3-night trip
Posted 2 hours ago
Baker's Cay Resort Key Largo, Curio Collection by Hilton
Amara Cay Resort

Amara Cay Resort

8/10 Good
"The resort is great! I did, however, leave behind my bathing suit and a personal towel hanging on the back of the bathroom door. When I called three days later after realizing they were missing, I learned that housekeeping had set the items aside. I was surprised that no one had contacted me to let me know they had been found. The front desk explained that I would need to provide a prepaid shipping label, which I promptly emailed. I asked for confirmation that the label had been received but received no response. After several days, I followed up again and still heard nothing. My items were eventually returned, and I’m grateful for that. Overall, I had a nice stay, but the lack of communication was disappointing. A more attentive, customer-focused team would have notified me that the items had been found and acknowledged receipt of the shipping label—especially after multiple messages. A little follow-through and basic courtesy would have made a significant difference."
Keith 2-night trip
Posted 3 hours ago
Amara Cay Resort
Islander Resort

Islander Resort

8/10 Good
"Great property with an amazing concept, especially in an area where there aren’t many high-end properties offering this style and experience. The facilities are excellent, and overall we really enjoyed our stay. My only negative feedback is that a few members of staff were constantly on their phones watching clips and videos, often with the volume turned up. We found this quite annoying, particularly when trying to relax quietly by the pool. It would be great if staff could be reminded to use headphones or keep phone use to a minimum in guest relaxation areas. Room maintaince could also be better."
Asoka 2-night trip
Posted 8 hours ago
Islander Resort
Three Waters Resort and Marina, Islamorada, a Tribute Portfolio Resort

Three Waters Resort and Marina, Islamorada, a Tribute Portfolio Resort

10/10 Excellent
"we loved it !!!"
Ilyan 2-night trip
Posted 20 hours ago
Three Waters Resort and Marina, Islamorada, a Tribute Portfolio Resort
Hawks Cay Resort

Hawks Cay Resort

10/10 Excellent
"Great place. Loved the area, the staff very helpful and nice. The villa could used a better cleaning but overall was a great stay, will definitely be back!!!"
Clara 3-night trip
Posted 23 hours ago
Hawks Cay Resort

Frequently asked questions

What are the best 4-star hotels in Florida Keys?
You'll discover a variety of 4-star hotels in Florida Keys, including in Key Largo. Playa Largo Resort & Spa, Autograph Collection is a customer favourite in this city that offers a tennis court and a sauna. Another stay that rates highly with travellers is Bakers Cay Resort Key Largo, Curio Collection by Hilton. Dining romance packages and private picnic options help make it their preferred choice.
How much does it cost to stay in a 4-star hotel in Florida Keys?
To find a 4-star hotel in Florida Keys that fits your budget, take advantage of Expedia's handy search filters. Take a look at the availability during your holiday dates and use our pricing filter to set your maximum rate. You can also sort your results by the most affordable retreat first.
  • Search for the lowest price from 6.277.446 ₫
What's the difference between 5-star and 4-star hotels in Florida Keys?
Offering a welcoming traveller experience and upmarket décor, 4-star hotels are an excellent option for your Florida Keys getaway. These types of accommodation generally feature loads of useful amenities that make it easy to unpack and relax — think pillowtop mattresses, pools and restaurants. Or live the high life at a 5-star hotel designed to spoil you with high-end perks and amenities. Concierge assistance, premium toiletries and fine dining are typically included at these deluxe properties.

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