Compare and book 4 Star hotels in Mesagne, Puglia
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Top Mesagne 4 Star Hotels

Grand Hotel Tiziano e dei Congressi
Lecce
7.4 out of 10, Good, (451)

Hotel Orientale
Brindisi Historic Center
9.0 out of 10, Wonderful, (450)

Palazzo Virgilio
Brindisi Historic Center
8.8 out of 10, Excellent, (363)
The price is 2.311.753 ₫
2.726.402 ₫ total
includes taxes & fees
8 Dec - 9 Dec

Hotel Executive Inn
Brindisi Historic Center
9.4 out of 10, Exceptional, (320)

Grande Albergo Internazionale
Brindisi Historic Center
8.2 out of 10, Very good, (427)

8Piuhotel
Lecce
9.6 out of 10, Exceptional, (784)
The price is 3.834.104 ₫
4.339.885 ₫ total
includes taxes & fees
25 Dec - 26 Dec

Hotel Monte Sarago
Ostuni
9.2 out of 10, Wonderful, (266)
The price is 2.761.094 ₫
3.220.677 ₫ total
includes taxes & fees
1 Dec - 2 Dec

Relais Sant'Eligio
Ostuni
8.8 out of 10, Excellent, (221)
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Explore similar 5-star hotels
Many 5-star hotels have the same amenities as 4-star hotels. See all 5-star hotels in Mesagne.

La Sommità Relais & Chateaux
Via S. Petrarolo, 7 Ostuni BR
9.2/10 Wonderful! (179 reviews)
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Learn more about Mesagne
The medieval castle dominates Mesagne's historic centre, where you can explore ancient walls and baroque churches. Join locals at Piazza Orsini del Balzo for evening aperitivo, then wander narrow lanes to discover family-run trattorias serving Puglian specialities.

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Accommodation near Mesagne attractions
- Hotels near Mesagne Castle
- Hotels near Torre Lapillo Beach
- Hotels near Lapillo Sea Tower
- Hotels near Lecce Obelisk
- Hotels near Togo Bay Beach
- Hotels near Nardo Technical Center
- Hotels near Riserva Natural Torre Guacceto
- Hotels near Porto Cesareo Beach
- Hotels near Torre Guaceto
- Hotels near Piazza del Duomo
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- Hotels near University of Salento
- Hotels near Perrino Hospital
- Hotels near Ionian Sea
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