A cityscape with historic buildings, a prominent church with a dome, and mountains in the background.

Compare and book 4 Star hotels in Palermo, Sicily

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on Palermo 4 Star Hotels

Tonight
8 Oct - 9 Oct
Tomorrow
9 Oct - 10 Oct
This weekend
9 Oct - 11 Oct
Next weekend
16 Oct - 18 Oct

Our top choices for Palermo 4-star hotels

A multi-story hotel with a prominent entrance labeled "ASTORIA PALACE."
A hotel room with a dining table, two wine glasses with rose petals, a sofa, a coffee table with a vase of flowers, and a clothing rack with white robes.
An outdoor dining area with tables and chairs, a covered seating area, and a view of a cityscape with buildings and a crane in the background.
A hotel room with a dining table set with a variety of desserts, two glasses of champagne, and a vase of flowers.

1. Astoria Palace Hotel

Astoria Palace Hotel
Monte Pellegrino
Australia
Blagoy
1.896.572 ₫
2.348.153 ₫ total
includes taxes & fees
31 Oct - 1 Nov
Astoria Palace Hotel
A spacious courtyard with a central fountain, surrounded by white wicker furniture and columns.
A spacious indoor area with a high ceiling, a chandelier, and a seating arrangement including tables and chairs.
A high-ceilinged atrium with a large skylight, ornate architectural details, and multiple balconies.
A spacious corridor with high ceilings and classical architecture, featuring columns and arches.

2. Grand Hotel Piazza Borsa

Grand Hotel Piazza Borsa
Palermo Historical Center
United Kingdom
Julie Margaret Owen
4.444.779 ₫
5.151.181 ₫ total
includes taxes & fees
1 Nov - 2 Nov
Grand Hotel Piazza Borsa
A terrace with wicker furniture, a potted plant, and a view of the cityscape.
A historic building with classical architecture, featuring a central dome and a courtyard.
A modern room with a bench, a round table, and two large abstract paintings on the wall.
A hotel room with a bed, a desk, a chair, a bathroom with a sink, mirror, and towel rack.

3. Hotel Politeama

Hotel Politeama
Politeama
United States
Daisy
2.772.696 ₫
3.311.890 ₫ total
includes taxes & fees
3 Nov - 4 Nov
Hotel Politeama
A man dining at a table with a view of a cruise ship and a building labeled "USCITA ELN" in the background.
A restaurant with outdoor seating, white chairs, and tables, overlooking a harbor with cranes and boats.
A modern hotel lobby with a red reception desk, a staircase, and potted plants.
A modern hotel room with a large bed, a small kitchenette, and a bathroom visible through an open door.

4. President Hotel Palermo

President Hotel Palermo
Politeama
United States
Jeffrey
2.528.762 ₫
3.043.562 ₫ total
includes taxes & fees
7 Nov - 8 Nov
President Hotel Palermo
A grand dining hall with ornate ceiling artwork, chandeliers, and multiple dining tables.
A grand lobby with a large arched doorway, a tufted sofa, and two ornate chairs.
A room with a large ornate table, two chairs, and a chandelier.
A grand staircase with marble columns and a statue at the top.

5. Eurostars Centrale Palace

Eurostars Centrale Palace
Palermo Historical Center
United States
Shaz
2.622.446 ₫
3.146.586 ₫ total
includes taxes & fees
1 Nov - 2 Nov
Eurostars Centrale Palace
A modern bedroom with a large bed, a bedside table, a mirror, and a wall-mounted artwork.
A spa area with a pool, lounge chairs, and candles.
A courtyard with a stone floor, yellow chairs, potted plants, and a building entrance.
A restaurant interior with tables and chairs, a sign reading "Locanda del Gusto", and an arched brick wall.

6. Quintocanto Hotel and Spa

Quintocanto Hotel and Spa
Palermo Historical Center
United States
molly
3.214.528 ₫
3.797.905 ₫ total
includes taxes & fees
5 Nov - 6 Nov
Quintocanto Hotel and Spa
A table with pastries, a teapot, and a cup, with a scenic view through large windows.
A staircase with a chandelier, a sign for San Paolo Palace Hotel Centro Congressi, and a view of greenery outside.
A clear blue pool with white lounge chairs and a railing.
A hotel with a large sign reading "SAN PAOLO PALACE" and a well-lit entrance area with potted plants.

7. San Paolo Palace Hotel

San Paolo Palace Hotel
Settecannoli
United States
CORINA
2.164.687 ₫
2.643.080 ₫ total
includes taxes & fees
1 Nov - 2 Nov
San Paolo Palace Hotel
Terrace/patio
Front of property
Room
A spacious lobby with a high ceiling, a turnstile entrance, and a seating area with a potted plant.

8. Cristal Hotel Palermo

Cristal Hotel Palermo
Politeama
Canada
Catherine
2.486.960 ₫
2.997.580 ₫ total
includes taxes & fees
4 Nov - 5 Nov
Cristal Hotel Palermo
A hotel with a swimming pool, lounge chairs, and a palm tree.
A hotel room with a large bed, a nightstand, a wall-mounted lamp, and a view of the sea through a large window.
A bar area with a marble countertop, patterned wall, and bar stools.
A room with a sofa, a small table, and a view of palm trees and a beach.

9. NH Palermo

NH Palermo
Palermo Historical Center
United Kingdom
Mia Susan
3.703.983 ₫
4.336.305 ₫ total
includes taxes & fees
3 Nov - 4 Nov
NH Palermo
A historic building with classical architecture, a fountain, and a street with cars and pedestrians.
A modern interior with a glass table, a bowl of fruit, and a wine glass.
A variety of potted flowers arranged on a sidewalk.
Exterior

10. Mercure Hotel Palermo Centro

Mercure Hotel Palermo Centro
Politeama
United States
Van
2.101.589 ₫
2.575.112 ₫ total
includes taxes & fees
2 Nov - 3 Nov
Mercure Hotel Palermo Centro
A seaside terrace with outdoor seating and a view of the sea and a mountain.
A spacious lobby with a high ceiling, wooden flooring, and a seating area with sofas and ottomans.
A spacious lobby with a red carpet, wooden flooring, and a large potted plant.
A covered outdoor dining area with tables set for a meal, overlooking the sea.

11. Splendid Hotel La Torre

Splendid Hotel La Torre
Partanna - Mondello
United States
Andrei
3.757.426 ₫
4.395.092 ₫ total
includes taxes & fees
2 Nov - 3 Nov
Splendid Hotel La Torre
A hotel lobby with a wooden-framed entrance leading to a dining area with tables and chairs.
A hotel lobby with a checkered floor, a reception desk, a red leather sofa, and a wall with a textured pattern.
The entrance to Hotel Federico II, featuring a checkered floor, a staircase, and a modern light fixture above the entrance.
A modern interior with a glass table and chairs, a decorative wall, and a sign indicating 'MAQUEDA HALL' and 'CONFERENCE HALL'.

12. Central Palace Hotel Federico II

Central Palace Hotel Federico II
Politeama
United States
Robin
3.687.092 ₫
4.319.166 ₫ total
includes taxes & fees
1 Nov - 2 Nov
Central Palace Hotel Federico II
A cityscape with a mountain in the background, buildings with balconies, and palm trees.
A modern hotel room with a bed, bedside tables, a desk with a chair, a TV, and a window with curtains.
A spiral staircase with a beige wall and black balusters.
A modern kitchen with red cabinetry, wooden dining tables, and chairs. There are multiple shelves with kitchenware and a central island with a sink.

13. Hotel Garibaldi

Hotel Garibaldi
Politeama
Australia
John
2.488.283 ₫
2.999.035 ₫ total
includes taxes & fees
8 Nov - 9 Nov
Hotel Garibaldi
A multi-story hotel with balconies, palm trees, and a well-maintained garden.
An outdoor seating area with tables and chairs, surrounded by greenery and illuminated by ambient lighting.
A hotel room with a large bed, a separate bathroom with a bathtub, and a mirror reflecting the room.
A modern living room with a black sofa, a coffee table, and a TV mounted on the wall. There is a staircase leading to another level.

14. Casena Dei Colli, Sure Hotel Collection by Best Western

Casena Dei Colli, Sure Hotel Collection by Best Western
Resuttano-San Lorenzo
United Kingdom
Jayne
1.784.526 ₫
2.224.903 ₫ total
includes taxes & fees
2 Nov - 3 Nov
Casena Dei Colli, Sure Hotel Collection by Best Western
A row of tables with white flowers, a glass railing, and a view of buildings in the background.
A bathroom with a bathtub, a stone staircase, and decorative baskets.
A red convertible car parked in front of a building with a black door and a sign that reads "Palladium Hotel."
A restaurant with a central bar area, clear glass tables, and chairs, and various plants and decorations on the walls.

15. Palazzo Natoli Boutique Hotel

Palazzo Natoli Boutique Hotel
Palermo Historical Center
Canada
Sasha
4.052.687 ₫
4.719.879 ₫ total
includes taxes & fees
5 Nov - 6 Nov
Palazzo Natoli Boutique Hotel
A modern restaurant interior with high ceilings, arched windows, and a long dining area with tables and chairs.
A multi-story building with balconies, a central archway, and doors numbered 110, 112, 114, and 116.
A reception desk with a modern design, featuring a dark wood finish and a geometric patterned wall behind it. There are three spherical pendant lights above the desk, and a potted plant is placed to the right.
A room with a round table, two chairs, a vase with flowers, a book, and a glass container with a lemon.

16. NH Collection Palermo Palazzo Sitano

NH Collection Palermo Palazzo Sitano
Palermo Historical Center
Mexico
Gustavo Mora
4.465.945 ₫
5.174.464 ₫ total
includes taxes & fees
3 Nov - 4 Nov
NH Collection Palermo Palazzo Sitano
A spacious hallway with a large painting, ornate chandeliers, and a view through a window.
A building facade with a sign reading "Hotel Cardino Angleste" and decorative ironwork.
A spacious living room with a piano, multiple armchairs, and a curved staircase.
A buffet table with various desserts and a fruit display.

17. Hotel Giardino Inglese

Hotel Giardino Inglese
Libertà
United Kingdom
Allison
4.478.908 ₫
5.188.723 ₫ total
includes taxes & fees
7 Nov - 8 Nov
Hotel Giardino Inglese
The entrance to the Artemisia Palace Hotel with a glass door, a signboard, and a potted plant in front.
A bakery display with various cakes and pastries.
A lobby with white columns, a statue, a reception desk, and a chandelier.
A hotel room with a bed, a bedside table, a mirror, and a door leading to a bathroom.

18. Artemisia Palace Hotel

Artemisia Palace Hotel
Politeama
Canada
Christine
2.977.066 ₫
3.538.137 ₫ total
includes taxes & fees
2 Nov - 3 Nov
Artemisia Palace Hotel
A restaurant with a checkered floor, large windows, and a city view.
A rooftop terrace with a checkered floor, two black chairs, a small table with a potted plant, and a view of city buildings and a mountain in the background.
A modern spa room with a rectangular hot tub, dark textured walls, and a vase with dried branches.
A spa area with massage chairs, a reception desk, and a storage area with towels and baskets.

19. Hotel Plaza Opera

Hotel Plaza Opera
Politeama
United States
Susan
4.047.924 ₫
4.714.641 ₫ total
includes taxes & fees
7 Nov - 8 Nov
Hotel Plaza Opera
A rooftop dining area with tables and chairs, overlooking a cityscape with domed buildings and mountains in the background.
A piano on a wooden floor with a patterned rug, a clock, and a small table with a decorative item.
A view through a window with curtains, featuring a building with a clock tower and mountains in the background.
A historic building with ornate balconies and a view of distant mountains.

20. Ambasciatori Hotel

Ambasciatori Hotel
Palermo Historical Center
United States
Hadia
3.026.657 ₫
3.591.247 ₫ total
includes taxes & fees
5 Nov - 6 Nov
Ambasciatori Hotel
Save an average of 15% on thousands of hotels when you're signed in

Explore similar 5-star hotels

Many 5-star hotels have the same amenities as 4-star hotels. See all 5-star hotels in Palermo.
Rocco Forte Villa Igiea

Rocco Forte Villa Igiea

Salita Belmonte 43 Palermo PA
21.165.537 ₫
23.669.244 ₫ total
8 Nov - 9 Nov
includes taxes & fees
9.6/10 Exceptional! (132 reviews)
Rocco Forte Villa Igiea
Grand Hotel et Des Palmes

Grand Hotel et Des Palmes

Via Roma 398 Palermo PA
13.889.936 ₫
15.569.956 ₫ total
7 Nov - 8 Nov
includes taxes & fees
Grand Hotel et Des Palmes
Grand Hotel Wagner

Grand Hotel Wagner

Via R. Wagner, 2 Palermo PA
5.833.641 ₫
6.708.178 ₫ total
8 Nov - 9 Nov
includes taxes & fees
9/10 Wonderful! (899 reviews)
Grand Hotel Wagner
Still don't see what you're looking for?
See all properties in Palermo.
You can also use these popular filters to refine your search.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Palermo

Wander through vibrant markets where vendors call out as you sample Sicily's best street food at Ballarò and Vucciria. Ancient Arab-Norman palaces and Byzantine mosaics await exploration, while the golden beaches of Mondello offer perfect afternoon escapes from the city.

See all hotels in Palermo
A historic cathedral with intricate architecture, a large dome, and a bell tower.

Top Palermo Hotel Reviews

Grand Hotel Piazza Borsa

Grand Hotel Piazza Borsa

8/10 Good
"The staff were really friendly and helpful."
Keir 1-night trip
Posted 21 hours ago
Grand Hotel Piazza Borsa
Splendid Hotel La Torre

Splendid Hotel La Torre

8/10 Good
"It is was all perfect!"
Ilia 1-night trip
Posted 1 day ago
Splendid Hotel La Torre
Hotel Politeama

Hotel Politeama

10/10 Excellent
"Great location and hotel!"
Daisy 3-night trip
Posted 2 days ago
Hotel Politeama
President Hotel Palermo

President Hotel Palermo

8/10 Good
"Hotel was nice, and provided a place to see most of downtown Palermo. Breakfast was typical Italian buffet."
Jeffrey 2-night trip
Posted 11 days ago
President Hotel Palermo
Hotel Plaza Opera

Hotel Plaza Opera

10/10 Excellent
"Close to historical center, nice staff, good breakfast."
Susan 1-night trip
Posted 3 weeks ago
Hotel Plaza Opera
Astoria Palace Hotel

Astoria Palace Hotel

8/10 Good
"It would be nice to have tea, coffe, or hot chocolate making facilities in the room."
Edward 5-night trip
Posted 1 month ago
Astoria Palace Hotel

Frequently asked questions

What are the best 4-star hotels in Palermo?
If you're seeking luxury comfort and loads of amenities on your Palermo holiday, consider Quintocanto Hotel and Spa. This popular 4-star hotel comes with spa facilities and treatment rooms. Eurostars Centrale Palace also gets great reviews from Expedia travellers. Spa facilities and beauty services are among its conveniences.
How much does it cost to stay in a 4-star hotel in Palermo?
We can help you quickly locate the ideal 4-star hotel for your holiday in Palermo. Use our filter tool to tailor your search by things like amenities, budget and property star rating and get access to fantastic deals in a couple of clicks.
  • Search for the lowest price from 6.708.178 ₫
What's the difference between 5-star and 4-star hotels in Palermo?
Treat yourself to luxury during your Palermo holiday by staying at a 4-star hotel. As well as featuring upmarket accommodation, these properties are usually packed with amenities like large beds, bathrobes and more. A 5-star hotel will go the extra mile to make your stay an even more indulgent and memorable one. 24-hour front desk, elegant décor and gourmet dining are a few of the superior services and conveniences you'll likely get access to.

Explore a world of travel with Expedia