A signpost with distance markers for Chicago and Los Angeles.

Find hotels in Adrian, TX from 2.001.519 ₫

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
6 Oct - 7 Oct
Tomorrow
7 Oct - 8 Oct
This weekend
9 Oct - 11 Oct
Next weekend
16 Oct - 18 Oct

Filter by

Star rating

Guest rating

Our top choices for Adrian hotels

A reception desk with a clock, a sign for Route 66 Country Inn, and a potted plant.
A Country Inn with a red and white color scheme, a reception desk, a coffee bar, and a large window with blinds.
A Country Inn with a covered parking area and a signboard.
A modern living room with a red accent wall, a white reception desk, and a large clock.

1. Route 66 Desert Rose Country Inn

Route 66 Desert Rose Country Inn
Vega
United States
Mark
1.786.866 ₫
2.001.519 ₫ total
includes taxes & fees
3 Nov - 4 Nov
Route 66 Desert Rose Country Inn
A swimming pool with white chairs around it, a tiled border, and a window with a view.
Two white front-loading washing machines side by side against a textured wall.
A modern building with a flat roof, large windows, and a covered entrance area.
A bathroom with a white bathtub, a shower with a handheld showerhead, a metal shelf with towels, and a step stool.

2. Days Inn by Wyndham Vega TX

Days Inn by Wyndham Vega TX
Vega
United States
Gerald
2.165.300 ₫
2.425.136 ₫ total
includes taxes & fees
2 Nov - 3 Nov
Days Inn by Wyndham Vega TX
View all properties
Save an average of 15% on thousands of hotels when you're signed in

Stay near popular Adrian attractions

Midway Point of Route 66

Stand at the exact midpoint of Route 66, where Chicago and Los Angeles are precisely 1,139 miles away. The historic Midpoint Café serves "ugly crust pies" in the spot that inspired Flo's V8 Café in Pixar's "Cars."
See properties

Learn more about Adrian

At the midpoint of Route 66, stop at the Midpoint Café for their famous 'ugly crust' pies and Route 66 memorabilia. Snap a photo with the town's midway marker, then chat with locals who'll share stories about this tiny highway community.

See all hotels in Adrian
A road with 'Midpoint' marking, a 'Welcome' sign, and a 'Route 66' symbol.

Top Adrian Hotel Reviews

Route 66 Desert Rose Country Inn

Route 66 Desert Rose Country Inn

10/10 Excellent
"Clean and comfortable room. Room was nice and clean. Owners were Very nice and accomadating !"
Steve 1-night trip
Posted 2 days ago
Route 66 Desert Rose Country Inn

More cheap stays in Adrian

Route 66 Desert Rose Country Inn

Route 66 Desert Rose Country Inn

1800 West Vega Boulevard Vega TX
1.786.866 ₫
2.001.519 ₫ total
3 Nov - 4 Nov
includes taxes & fees
8/10 Very good! (442 reviews)
Route 66 Desert Rose Country Inn
Days Inn by Wyndham Vega TX

Days Inn by Wyndham Vega TX

1005 S Main St Vega TX
2.165.300 ₫
2.425.136 ₫ total
2 Nov - 3 Nov
includes taxes & fees
Days Inn by Wyndham Vega TX

Hotels in Adrian with star rating

Frequently asked questions

What's the seasonal weather in Adrian?
The hottest months are usually July and August, with an average temperature of 25°C, while the coldest months are January and December, with an average of 6°C. Average annual precipitation for Adrian is 415 mm.

Explore a world of travel with Expedia