Byron Holiday Rentals, Minnesota: Private House Rentals

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Our top choices for Byron hotels

An outdoor patio area with yellow umbrellas, wicker furniture, and a sign for Centerstone Plaza Hotel.

A restaurant interior with wooden tables, chairs, and a stone wall.

A modern living room with a dark wall, a decorative light fixture, and a patterned wall art piece.

A modern reception area with a wooden reception desk, glass pendant lights, and a long hallway with seating.

1. Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area

Historic Southwest

Sarah

2.978.100 ₫

3.428.537 ₫ total

includes taxes & fees

6 Sept - 7 Sept

A reception area with a wooden reception desk, a "Welcome to the Bread & Butter State" sign, and a "Please Center" sign.

A coffee station with four coffee dispensers, a stack of disposable cups, and a tray with various coffee-related items.

A pool area with a table and chairs, a lifeguard chair, and a pool lift.

A modern lounge area with seating arrangements, a reception desk, and a patterned wall.

2. Hampton Inn Rochester-South

Rochester

Lynne

2.651.611 ₫

3.052.666 ₫ total

includes taxes & fees

7 Sept - 8 Sept

An indoor swimming pool with slides, seating areas, and a covered section with umbrellas.

A modern kitchen with black cabinets, white countertops, and a tiled backsplash. There are pendant lights, a refrigerator, and a coffee machine.

A modern kitchen with granite countertops, a built-in microwave, and a sink. There are two wooden chairs and a small table.

A hotel room with two beds, a desk with a chair, a TV, and a window with curtains.

3. Best Western Rochester Hotel Mayo Clinic Area/St. Mary's

Rochester

Margita

2.576.506 ₫

2.966.202 ₫ total

includes taxes & fees

20 Sept - 21 Sept

An indoor swimming pool with clear water, wooden flooring, and a ceiling with wooden beams and lights.

A gym with treadmills, an elliptical, and a water station.

A room with a TV mounted on the wall, a wooden table, and two patterned armchairs.

A café with multiple tables and chairs, a kitchen area with appliances, and a clock on the wall.

4. Med City Inn & Suites - Mayo Clinic Area

Kutzky Park

Hailey

1.971.497 ₫

2.269.686 ₫ total

includes taxes & fees

31 Aug - 1 Sept

A poolside area with wicker chairs and potted plants, a tiled floor, and a clear view of the pool.

A hotel room with a sofa, two beds, a large window, and a framed artwork on the wall.

A reception area with a wooden reception desk, a clock, and a wall-mounted display.

A restaurant with a bar area, wooden chairs, and a stone wall.

5. Kahler Inn and Suites - Mayo Clinic Area

Downtown Rochester

Valarie

3.262.358 ₫

3.755.789 ₫ total

includes taxes & fees

3 Sept - 4 Sept

A room with a fireplace, two leather armchairs, a sofa, and a large window providing a view of the outdoors.

A hotel room with a bed, a sink, a microwave, and a window with curtains.

A paved garden area with two benches, a potted plant with yellow flowers, and a variety of greenery.

A reception area with a curved counter, ceiling lights, and a potted plant.

6. Brentwood Inn & Suites

Downtown Rochester

Bryan

3.259.750 ₫

3.752.885 ₫ total

includes taxes & fees

3 Sept - 4 Sept

An outdoor seating area with wooden pillars, colorful striped cushions, and potted plants.

A modern restaurant with a counter, seating area, and a TV screen.

A modern hotel room with a bed, desk, and kitchenette.

An indoor swimming pool with wooden ceiling beams, yellow chairs, and tables along the sides.

7. Home2 Suites by Hilton Rochester Mayo Clinic Area

Rochester

Vickie

3.186.210 ₫

3.668.125 ₫ total

includes taxes & fees

7 Sept - 8 Sept

A modern outdoor seating area with a built-in fireplace, two wooden chairs, a table, and a sofa.

A modern kitchen with a central island, bar stools, and pendant lighting. A living area with a sofa, ottoman, and a view of the outdoors is visible.

A modern interior with a dining area, a kitchen, and a pantry stocked with snacks.

A gym with various exercise equipment, including treadmills, stationary bikes, and weight machines.

8. Staybridge Suites Rochester - Mayo Clinic Area by IHG

Kutzky Park

matthew

2.686.034 ₫

3.144.454 ₫ total

includes taxes & fees

5 Sept - 6 Sept

A hotel entrance with a stone facade, a glass door, and a metal roof structure.

An outdoor patio area with brick walls, a large arched window, and outdoor seating.

A hotel room with a large bed, a TV, a bathroom with a sink and mirror, and a window with curtains.

A spa area with a hot tub, exercise equipment, and a seating area with chairs and a table.

9. Aspen Suites

Rochester

Dr. suzette

3.302.779 ₫

3.992.542 ₫ total

includes taxes & fees

3 Sept - 4 Sept

A hotel room with a large bed, a desk, a chair, a TV, and a window with curtains.

A hotel room with a large window, a clock, a framed picture of pottery, a desk with a computer, and a seating area with patterned chairs.

A Microtel Inn & Suites building with a signboard, a parking lot, and a clear sky.

A reception area with a reception desk, two armchairs, a clock, and a framed artwork on the wall.

10. Microtel Inn & Suites by Wyndham Rochester North Mayo Clinic

Rochester

Siddhartha

1.817.897 ₫

2.092.856 ₫ total

includes taxes & fees

2 Sept - 3 Sept

A hotel room with a large bed, a desk with a chair, a window with a view of the outdoors, and two bedside lamps.

11. Comfort Inn & Suites Rochester South Mayo Clinic

Rochester

Deborah

2.163.431 ₫

2.490.650 ₫ total

includes taxes & fees

30 Sept - 1 Oct

A modern dining area with high tables, chairs, and pendant lighting.

A swimming pool with a tiled deck, sun loungers, and a lifeguard chair.

A hotel room with two beds, a desk with a computer, a chair, and a window with a view.

A reception desk with a large digital screen displaying a cityscape and the word "happy."

12. Hampton Inn & Suites Rochester-North

Rochester

Albert

2.672.995 ₫

3.077.285 ₫ total

includes taxes & fees

27 Sept - 28 Sept

A modern hotel lobby with multiple seating areas, including a central dining table with chairs, a bar area, and a seating section with cushioned chairs.

A hotel reception desk with a modern design, a clock, and a digital screen.

A modern conference room with a long table, multiple chairs, and a wooden partition.

A modern hotel room with a large bed, two bedside tables, and built-in lighting.

13. SpringHill Suites by Marriott Rochester-Mayo Clinic/St Marys

Kutzky Park

Tricia

2.792.954 ₫

3.215.387 ₫ total

includes taxes & fees

11 Sept - 12 Sept

A compact kitchen with white cabinets, a microwave, a refrigerator, a sink, and a chair.

A hotel lobby with two leather armchairs, a small round table, a 'WELCOME' sign, and a 'TRASH CAN' sign on the wall.

A multi-story hotel with a brick facade, a covered lobby entrance, and a parking lot with several cars.

14. Extended Stay America Suites Rochester North

Rochester

Rick

1.783.474 ₫

2.053.121 ₫ total

includes taxes & fees

31 Aug - 1 Sept

A swimming pool with clear blue water, surrounded by lounge chairs and a view of residential buildings through large windows.

An outdoor patio area with wicker furniture, a central fire feature, and a stone building in the background.

A modern lounge area with seating, a fireplace, and a bar area.

A modern reception area with a brick-patterned wall, two reception desks, a flat-screen TV, and seating arrangements including a sofa and chairs.

15. Residence Inn by Marriott Rochester Mayo Clinic Area South

Rochester

Richard

3.572.686 ₫

4.113.055 ₫ total

includes taxes & fees

11 Sept - 12 Sept

An outdoor patio area with a concrete floor, wooden fence, and string lights.

A breakfast bar with a wooden counter, a coffee machine, and a refrigerator.

A Fairfield Inn & Suites hotel with a modern design, featuring a prominent entrance and a parking area.

16. Fairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys

Kutzky Park

Jon

2.910.305 ₫

3.350.489 ₫ total

includes taxes & fees

18 Sept - 19 Sept

A restaurant with wooden tables and bar stools, a bar area with a counter, and multiple televisions mounted on the walls.

A hotel room with two beds, a desk, a chair, and a mirror.

A bar with wooden stools and a neon sign.

A modern kitchen with wooden cabinets, a microwave, an oven, and a dishwasher.

17. AmericInn by Wyndham Rochester Near Mayo Clinic

Rochester

Cathy

2.031.737 ₫

2.339.037 ₫ total

includes taxes & fees

6 Sept - 7 Sept

An outdoor patio area with stone walls, outdoor seating, and landscaped gardens.

A modern kitchen with dark wooden cabinets, a stainless steel refrigerator, a microwave, and a coffee maker. There is a dining area with two red chairs and a table.

A Staybridge Suites hotel with a stone facade, multiple windows, and a signboard.

An indoor swimming pool with clear lane markings, a lifeguard chair, and a pool capacity sign.

18. Staybridge Suites Rochester - Commerce Dr NW by IHG

Rochester

Tamra

3.311.906 ₫

3.812.864 ₫ total

includes taxes & fees

6 Sept - 7 Sept

A coffee shop interior with a wooden counter, menu boards, and seating area.

A hotel room with a bed, bedside table, and a window with curtains.

An outdoor seating area with tables and chairs, a neon sign, and flower arrangements.

A hotel exterior with a 'Townplace Suites' sign, outdoor seating area, and 'OPEN' signage.

19. TownePlace Suites by Marriott Rochester Mayo Clinic Area

Kutzky Park

Jorge

3.311.906 ₫

3.812.833 ₫ total

includes taxes & fees

4 Sept - 5 Sept

A hotel breakfast area with a self-serve station, including a waffle maker, toaster, and various food items.

A hotel lobby with a patterned carpet, two beige armchairs, a small table, a clock, a fire extinguisher, and a staircase.

A hotel room with a large bed, bedside tables, a mirror, and a patterned carpet.

A compact kitchen with a microwave, refrigerator, and coffee maker. A small bar stool is near the counter.

20. Quality Inn & Suites Mayo Clinic Area

Rochester

Cassandra

1.994.967 ₫

2.324.871 ₫ total

includes taxes & fees

20 Sept - 21 Sept

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Stay near popular Byron attractions

Somerby Park

Somerby Park is just one of the places to see in Byron, so why not enjoy the other things to explore during your travels? Amble around the area's parks or experience its art scene.

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Oxbow Park

8.8/10 (5 reviews)

Explore the great outdoors at Oxbow Park, a lovely green space in Byron. Visit the top-notch restaurants or cosy cafes in this walkable area.

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Salem Glen Winery

You can enjoy a tasting or tour at Salem Glen Winery during your travels to Byron. Amble around the area's parks or experience its art scene.

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East Brookfield Park

After visiting East Brookfield Park, make a plan to see the other sights and activities in Byron. Amble around the area's parks or experience its art scene.

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Salem Town Hall

After visiting Salem Town Hall, make a plan to see the other sights and activities in Byron. Amble around the area's parks or experience its art scene.

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Cheery Meadows Center

You can do some window-shopping at Cheery Meadows Center during your trip to Byron. Amble around the area's parks or experience its art scene.

See properties

Somerby Golf Club

Enjoy a round of golf in Byron at Somerby Golf Club. Amble around the area's parks or experience its art scene.

See properties

Valley View Park

Valley View Park is just one of the places to see in Byron, so why not enjoy the other things to explore during your travels? Amble around the area's parks or experience its art scene.

See properties

Top Byron Hotel Reviews

Brentwood Inn & Suites

10/10 Excellent

"My room was very clean, the staff were friendly and helpful, and the room rate for two queen beds was very reasonable."

Staybridge Suites Rochester - Mayo Clinic Area by IHG

10/10 Excellent

"Great property. Free breakfast, happy hour a few days, huge lobby and patio are. Convenient shuttle to Mayo Clinic. Fully stocked kitchens, coffee, and dishwasher. Laundry on site if needed."

Aspen Select

10/10 Excellent

"Construction in the area is crazy, but if you are looking for a good price near the Mayo Clinic then this is your hotel. The sister property was almost 3x the price. Still has good access during Mayo construction. Directly across from Saint Mary’s"

Kahler Grand Hotel

8/10 Good

"Toilets were too low for seniors….put higher toilets in. It is ridicules to have to sit almost of the floor, especially in room 562!!! Otherwise every thing was wonderful!!"

Hyatt House Rochester/Mayo Clinic Area

10/10 Excellent

"This property has a good location and since it’s newer, that’s an added bonus. They have a complimentary, elevated breakfast which is great."

SpringHill Suites by Marriott Rochester-Mayo Clinic/St Marys

8/10 Good

"Check out was very confusing. It took about a half hour and I am still not sure if the billing was correct. Food was fine."

Kahler Inn and Suites - Mayo Clinic Area

10/10 Excellent

"The hotel was nice and clean, staff were very pleasant, breakfast was a big tasty buffet. The only complaint was the parking garage was very little and barely fit my mid size SUV because of how low the ceiling was, but there is another garage next to the hotel that was actually cheaper. Also, being on the side where all the construction was going on, but I get it they had to start super early because of the heat. Most importantly though it was with walking distance from all of my Mayo appts and several restaurants."

Hotel Indigo Rochester – Mayo Clinic Area by IHG

10/10 Excellent

"This is my first time staying at Hotel Indigo. The staff was amazing. I had to keep adding nights and they were so accommodating. The room was just right. It was clean , well stocked and easy access to the Mayo Clinic. I really liked the front desk people. Super friendly and helpful. Love the attached restaurant!"

More cheap stays in Byron

Super 8 by Wyndham Rochester Mayo Clinic Area

106 SE 21st Street Rochester MN

1.418.643 ₫

1.633.213 ₫ total

6 Sept - 7 Sept

includes taxes & fees

7.8/10 Good! (1,002 reviews)

Quality Inn near Medical Center

5708 Bandel Road NW Rochester MN

1.640.306 ₫

1.888.403 ₫ total

20 Sept - 21 Sept

includes taxes & fees

7.8/10 Good! (950 reviews)

Med City Inn & Suites - Mayo Clinic Area

435 16th Ave Nw Rochester MN

1.971.497 ₫

2.269.686 ₫ total

31 Aug - 1 Sept

includes taxes & fees

8/10 Very good! (1,007 reviews)

Best Western Rochester Hotel Mayo Clinic Area/St. Mary's

1517 16th St Sw Rochester MN

2.576.506 ₫

2.966.202 ₫ total

20 Sept - 21 Sept

includes taxes & fees

Hampton Inn Rochester-South

1755 S Broadway Rochester MN

2.651.611 ₫

3.052.666 ₫ total

7 Sept - 8 Sept

includes taxes & fees

Brentwood Inn & Suites

123 Fourth Ave. NW Rochester MN

3.259.750 ₫

3.752.885 ₫ total

3 Sept - 4 Sept

includes taxes & fees

8.8/10 Excellent! (1,002 reviews)

Hotels in Byron with star rating

Frequently asked questions

What's the seasonal weather in Byron?

The hottest months are usually July and August, with an average temperature of 20°C, while the coldest months are January and February, with an average of -6°C. The snowiest months in Byron are January, March, April and February, with each month seeing an average of 19 cm of snowfall.

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Book Hotels in Byron on Expedia.com

Find hotels in Byron, MN from 1.633.213 ₫

Change your mind

Treat yourself

Be picky

Go beyond your typical stay in Byron

Check prices for these dates

Filter by

Star rating

Guest rating

Our top choices for Byron hotels

1. Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area

2. Hampton Inn Rochester-South

3. Best Western Rochester Hotel Mayo Clinic Area/St. Mary's

4. Med City Inn & Suites - Mayo Clinic Area

5. Kahler Inn and Suites - Mayo Clinic Area

6. Brentwood Inn & Suites

7. Home2 Suites by Hilton Rochester Mayo Clinic Area

8. Staybridge Suites Rochester - Mayo Clinic Area by IHG

9. Aspen Suites

10. Microtel Inn & Suites by Wyndham Rochester North Mayo Clinic

11. Comfort Inn & Suites Rochester South Mayo Clinic

12. Hampton Inn & Suites Rochester-North

13. SpringHill Suites by Marriott Rochester-Mayo Clinic/St Marys

14. Extended Stay America Suites Rochester North

15. Residence Inn by Marriott Rochester Mayo Clinic Area South

16. Fairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys

17. AmericInn by Wyndham Rochester Near Mayo Clinic

18. Staybridge Suites Rochester - Commerce Dr NW by IHG

19. TownePlace Suites by Marriott Rochester Mayo Clinic Area

20. Quality Inn & Suites Mayo Clinic Area

Stay near popular Byron attractions

Somerby Park

Oxbow Park

Salem Glen Winery

East Brookfield Park

Salem Town Hall

Cheery Meadows Center

Somerby Golf Club

Valley View Park

Top Byron Hotel Reviews

Brentwood Inn & Suites

Staybridge Suites Rochester - Mayo Clinic Area by IHG

Aspen Select

Kahler Grand Hotel

Hyatt House Rochester/Mayo Clinic Area

SpringHill Suites by Marriott Rochester-Mayo Clinic/St Marys

Kahler Inn and Suites - Mayo Clinic Area

Hotel Indigo Rochester – Mayo Clinic Area by IHG

More cheap stays in Byron

Super 8 by Wyndham Rochester Mayo Clinic Area

Quality Inn near Medical Center

Med City Inn & Suites - Mayo Clinic Area

Best Western Rochester Hotel Mayo Clinic Area/St. Mary's

Hampton Inn Rochester-South

Brentwood Inn & Suites

Hotels in Byron with star rating

Frequently asked questions

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