The Best Hotels Closest to Calle 50 in Panama City - 2026 Updated Prices

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Our top choices for Calle 50 hotels

A balcony with wicker chairs and a view of the cityscape.

A reception area with a marble wall, a 'Free Wireless Internet' sign, and a floral arrangement.

A multi-story hotel with a modern facade, large windows, and a prominent entrance with a covered area.

A rooftop pool area with a view of high-rise buildings in the background.

1. Ramada Plaza by Wyndham Panama Punta Pacifica

San Francisco, 1 km from Calle 50

Bettyanne

2.841.421 ₫

3.125.563 ₫ total

includes taxes & fees

28 Aug - 29 Aug

A pool area with lounge chairs and umbrellas, surrounded by greenery and a multi-story building in the background.

A spacious lobby with a curved ceiling, a central staircase, and a reception desk.

A modern interior with a central seating area, potted plants, and a staircase.

A spacious hotel lobby with modern furniture, large windows, and a city view.

2. Hyatt Regency Panama City

Campo Alegre, 1 km from Calle 50

Deanna

5.849.984 ₫

6.434.982 ₫ total

includes taxes & fees

15 Sept - 16 Sept

A modern living room with a sectional sofa, a small ottoman, a flat-screen TV, and abstract art on the walls.

A covered outdoor area with artificial grass, a seating arrangement, and a decorative chair.

A dining area with a marble floor, a modern chandelier, and a vase with red flowers on the table.

A neatly made bed with a wooden headboard, two bedside tables with lamps, and a large wardrobe.

3. Casa Bianca

Bella Vista, 1.8 km from Calle 50

Jose A

4.348.314 ₫

4.783.145 ₫ total

includes taxes & fees

25 Aug - 26 Aug

A covered outdoor seating area with a view of a city skyline and water.

A hotel room with two beds, a desk, and a large window offering a city view.

A cityscape with high-rise buildings, a waterfront, and a modern sculpture.

A nighttime view of a high-rise building complex with illuminated windows and a prominent red-lit structure.

4. Plaza Paitilla Inn Hotel

Punta Paitilla, 1.3 km from Calle 50

Gilberto

2.996.524 ₫

3.296.176 ₫ total

includes taxes & fees

6 Sept - 7 Sept

A modern living room with a sofa, armchair, dining table, and kitchen area with a TV and appliances.

A swimming pool with clear water, surrounded by high-rise buildings under a partly cloudy sky.

A modern kitchen with a dining area, a flat-screen TV, and a view of the cityscape through the window.

A modern living room with a glass dining table, black chairs, a grey sofa, and a large window with a city view.

5. Modern Apartments at The Gray Prime Location

Campo Alegre, 1.4 km from Calle 50

Tiyania

2.029.997 ₫

2.232.997 ₫ total

includes taxes & fees

26 Aug - 27 Aug

A modern lobby with a chandelier, seating area, reception desk, and a staircase.

A modern hotel lobby with a marble reception desk, comfortable seating, a large painting, and a large plant.

A hotel dining area with wicker chairs, a bar counter, and pendant lighting.

A lobby with a reception desk, seating area, and a bar.

6. The Executive Hotel

Campo Alegre, 1.2 km from Calle 50

Gracia

2.316.477 ₫

2.548.125 ₫ total

includes taxes & fees

31 Aug - 1 Sept

A modern hotel entrance with a prominent 'NOVOTEL' sign, large glass windows, and geometric light patterns on the facade.

A buffet setup with various food items, including bread, pastries, and a variety of dishes in bowls.

A hotel room with a bed and a view of a cityscape through sheer curtains.

A bar area with a variety of liquor bottles, a counter, and seating with tables and chairs.

7. Novotel Panama City

El Cangrejo, 1.1 km from Calle 50

Zaccaria

2.797.024 ₫

3.076.726 ₫ total

includes taxes & fees

21 Sept - 22 Sept

A hotel named PRINCIPE with a modern facade and large glass windows.

A hotel room with a TV mounted on the wall, a large mirror, and a red bedspread.

A swimming pool with lounge chairs and a table.

A hotel lobby with a reception desk, seating area, and a visible sign for 'PRINCIPES HOTEL & SQUITES'.

8. Principe Hotel and Suites

El Cangrejo, 0.9 km from Calle 50

Lashell

1.544.239 ₫

1.698.585 ₫ total

includes taxes & fees

25 Aug - 26 Aug

A rooftop pool with sun loungers and umbrellas, surrounded by palm trees and modern buildings.

A modern hotel room with a dining area, a TV, and a city view.

A hotel room with a bed, a TV, a desk, and a view of the cityscape through a window.

A spacious lobby with a central seating area, a chandelier, and a modern ceiling design.

9. Hotel Riu Plaza Panama

Campo Alegre, 0.7 km from Calle 50

Lori

3.594.645 ₫

3.954.109 ₫ total

includes taxes & fees

15 Sept - 16 Sept

A rooftop pool with clear blue water, surrounded by palm trees and a city skyline in the background.

An outdoor café with multiple wooden tables and chairs, surrounded by greenery and decorative elements.

A modern hotel room with a large bed, a wardrobe, a desk with a chair, and a decorative wall piece.

A restaurant with wooden tables and chairs, hanging plants, and circular wall decorations.

10. Gran Evenia Panama

El Cangrejo, 1 km from Calle 50

Sheyla

2.777.698 ₫

3.055.572 ₫ total

includes taxes & fees

29 Aug - 30 Aug

A multi-story hotel with a Marriott sign, surrounded by high-rise buildings and a busy street with cars.

A modern cafe with wooden tables and chairs, large windows, and decorative vases on shelves.

A modern reception area with a wooden panel wall, a sign indicating 'Marriott Bonvoy', and three reception desks with digital displays.

A modern lounge area with a wooden partition, a bar with a variety of bottles, and a seating area with chairs.

11. Courtyard by Marriott Panama Multiplaza Mall

San Francisco, 0.4 km from Calle 50

Shereen

3.085.605 ₫

3.394.035 ₫ total

includes taxes & fees

6 Sept - 7 Sept

A rooftop pool with sun loungers and a city skyline in the background.

A bar area with a curved counter, multiple screens, and a patterned carpet.

A modern hotel room with a large flat-screen TV, a desk, a comfortable armchair, a bed, a bedside table, and a view of the city through the window.

A long, narrow hallway with a wooden floor and light-colored walls.

12. Waymore Hotel Spa & Casino

El Cangrejo, 1.4 km from Calle 50

Amrit

2.232.918 ₫

4.467.142 ₫ total

includes taxes & fees

25 Aug - 26 Aug

A high-rise hotel with multiple floors, a prominent "Residence Inn by Marriott" sign, and a "Panama Clinic" sign.

A modern conference room with a long table, colorful chairs, and large windows offering a city view.

A modern bar area with multiple seating options and a view of the cityscape.

A modern hotel pool with a glass barrier, surrounded by high-rise buildings and a sunset view.

13. Residence Inn by Marriott Panama City

Punta Paitilla, 1 km from Calle 50

Frank David Delgado

5.614.940 ₫

6.176.434 ₫ total

includes taxes & fees

11 Sept - 12 Sept

A modern living room with a sofa, round black ottomans, and a vase of flowers. A cityscape is visible through the window.

A rooftop swimming pool with a cityscape view, glass railings, and a modern architectural design.

A person performing a yoga pose in a living room with a large window and a sofa.

A bar area with a long counter, multiple bar stools, and a television screen. There are large windows providing natural light and a view of the outdoors.

14. Bristol Panama, a Registry Collection Hotel

Bella Vista, 1.1 km from Calle 50

Rafael

5.852.596 ₫

6.437.856 ₫ total

includes taxes & fees

28 Aug - 29 Aug

15. San Francisco by Wynwood House

San Francisco, 1.2 km from Calle 50

Claire

2.802.625 ₫

3.735.788 ₫ total

includes taxes & fees

30 Aug - 31 Aug

A hotel entrance with a covered walkway, large windows, and a well-maintained garden area.

A spacious lobby with a blue sofa set, a coffee table, and a green ottoman. There is a large window with a view of palm trees outside.

A lobby with seating areas, a reception desk, and a chandelier.

A hotel reception area with a desk, chairs, and a computer.

16. Hotel Milan

El Cangrejo, 1.3 km from Calle 50

Gale

1.044.640 ₫

1.149.104 ₫ total

includes taxes & fees

2 Sept - 3 Sept

An outdoor patio area with tables and chairs, a pool, and a covered seating area.

A small, clean room with a white air conditioner, a white refrigerator, a flat-screen TV mounted on the wall, and a bed with a white mattress.

A hallway with a white wall featuring a motivational quote.

Two single beds with white linens, a teal nightstand with a lamp, and a wall-mounted picture of grapes.

17. Hostal Familiar Carmencita - Hostel

Bella Vista, 1.1 km from Calle 50

Brooke

1.121.160 ₫

1.233.276 ₫ total

includes taxes & fees

25 Aug - 26 Aug

A modern building with a sign reading "LA RESIDENCE" and a car parked in front.

A spacious living area with modern furniture, a round coffee table, and a large window offering a view of the outdoors.

A bedroom with a large TV mounted on a marble wall, a bed, and a wooden cabinet.

A dining area with a table set for two, featuring a plate of food, a glass of orange juice, and a coffee cup.

18. La Résidence Panamá

Campo Alegre, 1 km from Calle 50

Mohamad

3.575.020 ₫

3.932.522 ₫ total

includes taxes & fees

29 Aug - 30 Aug

A rooftop pool with lounge chairs and a city skyline view.

A tall hotel with a modern design, featuring a large glass facade and a covered entrance area.

A person seated on a wicker chair with a view of a cityscape through large windows.

A modern kitchen with a granite countertop, bar stools, and a decorative ceiling with geometric patterns.

19. Hotel Dann Carlton Panamá

Campo Alegre, 1.2 km from Calle 50

eisman

2.610.479 ₫

3.589.717 ₫ total

includes taxes & fees

22 Sept - 23 Sept

A hotel with a rooftop pool, outdoor seating, and a sign reading "TRYP BY WYNHAM".

The exterior of the Panama Center building with a red awning, glass entrance, and palm trees in the foreground.

A modern hotel lobby with a reception desk, seating area, and a cityscape mural.

A TRYP PANAMA CENTRO reception area with a modern design, including a reception desk, seating area, and a large screen.

20. TRYP by Wyndham Panamá Centro

El Cangrejo, 1.4 km from Calle 50

Daphnee

2.330.853 ₫

2.563.938 ₫ total

includes taxes & fees

10 Sept - 11 Sept

View all properties

Compare popular hotels close to Calle 50

Property	Property class	Guest rating
Ramada Plaza by Wyndham Panama Punta Pacifica	9.6 Exceptional 1,321 reviews	View
Hyatt Regency Panama City	9.6 Exceptional 421 reviews	View
Casa Bianca	9.8 Exceptional 8 reviews	View
Plaza Paitilla Inn Hotel	9.4 Exceptional 2,236 reviews	View
Modern Apartments at The Gray Prime Location	9.4 Exceptional 8 reviews	View

Top Calle 50 Hotel Reviews

Aloft by Marriott Panama

10/10 Excellent

"Buena atencion y buenos desayunos! Los ventanales de las habitaciones podrian mantenerlos más limpios pero se entiende que el clima no siempre lo permite. Todo lo demás muy bien!"

Las Americas Golden Tower Panama

10/10 Excellent

"Muy bueno"

Courtyard by Marriott Panama Multiplaza Mall

10/10 Excellent

"I live in Panama so when I travel back to the US, I always stay the night before here. 1st class place. Easy shuttle and the employees are the best. I only stay here when I travel. Food is great as well, rooms are clean and comfortable."

Ramada Plaza by Wyndham Panama Punta Pacifica

10/10 Excellent

"Friendly and professional staff."

Novotel Panama City

10/10 Excellent

"An amazing experience with lovely amenities and little surprises. Would definitely recommend to others. Walking distance to shops and restaurants."

Renaissance Panama City Hotel

10/10 Excellent

"Great hotel"

Hotel El Panama by Faranda Grand, a member of Radisson Individuals

10/10 Excellent

"Todo estaba súper Lindo y limpio y muy cómodo para el precio creo que estuve súper, pero la única razón por la que no doy las 5 estrellas, es por que el baño, en la zona de la tina estaba llena de moho negro incluso la cortina blanca se le podía ver el Moho negro. Las orillas de la tina también. De resto todo súper chévere"

Decapolis Hotel Panama City

10/10 Excellent

"The check in and check out process was efficient and everything went smoothly. The breakfast buffet is a good introduction to local cuisine with a mix of international flavour."

Other attractions near Calle 50

A modern building facade with vertical reflective panels and the word "GUCCI" prominently displayed.

Multiplaza Pacific Mall

9.0/10 (4,497 reviews)

During your trip to Panama City, you can search for that perfect souvenir at Multiplaza Pacific Mall. You can enjoy the restaurants while in the area.

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A spiraling skyscraper against a clear blue sky.

Soho City Center

You can enjoy retail therapy at Soho City Center during your trip to Panama City. Discover the area's casinos or seek out its local tours.

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A nighttime cityscape with illuminated skyscrapers and a river reflecting the lights.

Avenida Balboa

8.8/10 (3,608 reviews)

You can browse for the perfect souvenirs at Avenida Balboa during your stay in Panama City. While you're in the area, wander around the natural setting.

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Bingo 90

7.0/10 (12 reviews)

Why not roll the dice with a visit to Bingo 90 during your travels in Panama City? Visit the casinos and shops in this vibrant area.

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Pacific Center

You can browse for the perfect souvenirs at Pacific Center during your visit to Panama City. You can enjoy the restaurants while in the area.

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National Shrine of the Heart of Mary

9.0/10 (17 reviews)

You can learn about the history of Panama City with a trip to National Shrine of the Heart of Mary. Stroll along the seaside or visit the shops in this vibrant area.

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Multicentro Panama

8.2/10 (274 reviews)

During your trip to Panama City, you can find the perfect gifts to bring home at Multicentro Panama. Stroll along the seaside or visit the casinos in this vibrant area.

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Crown Casino

7.8/10 (412 reviews)

Why not roll the dice with a visit to Crown Casino during your visit to Panama City? Stroll along the seaside or visit the shops in this vibrant area.

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Frequently asked questions

What's the area like around Calle 50?

Calle 50 is located in Panama City. This welcoming area is known for its array of dining options and major shopping area. If you're looking for a convenient place to stay, take a look at the 485 hotels and other accommodation options you'll find within a mile.

How many hotels can I expect to find near Calle 50?

Expedia has 485 hotels and other accommodation options within a mile from Calle 50.

If I need to cancel the hotel reservation for my stay near Calle 50, will I receive a refund?

Yes, the majority of hotel bookings are fully refundable if cancelled before the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of check in. If you booked a non-refundable reservation, you might be able to still cancel and get a refund within 24 hours of your booking. Enter dates in and click on "Search", then use the filter option "fully refundable" to review the best options available near Calle 50.

What can I see and do near Calle 50?

You'll want to browse the collections at Interoceanic Canal Museum, Biomuseo and Colonial Religious Art Museum. Iglesia del Carmen, Panama Viejo and Panama Canal Railway are notable landmarks to explore if you're in the area. You can catch a show at National Theater, Theater Circle and Anita Villalaz Theater.

How can I get to Calle 50?

Nearby metro stations include Iglesia del Carmen Station and Vía Argentina Station. If you'd like to explore farther outside of the area, you may want a car rental for your journey.

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Search Hotels Near Calle 50, Panama City

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Treat yourself

Be picky

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Star rating

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Our top choices for Calle 50 hotels

1. Ramada Plaza by Wyndham Panama Punta Pacifica

2. Hyatt Regency Panama City

3. Casa Bianca

4. Plaza Paitilla Inn Hotel

5. Modern Apartments at The Gray Prime Location

6. The Executive Hotel

7. Novotel Panama City

8. Principe Hotel and Suites

9. Hotel Riu Plaza Panama

10. Gran Evenia Panama

11. Courtyard by Marriott Panama Multiplaza Mall

12. Waymore Hotel Spa & Casino

13. Residence Inn by Marriott Panama City

14. Bristol Panama, a Registry Collection Hotel

15. San Francisco by Wynwood House

16. Hotel Milan

17. Hostal Familiar Carmencita - Hostel

18. La Résidence Panamá

19. Hotel Dann Carlton Panamá

20. TRYP by Wyndham Panamá Centro

Compare popular hotels close to Calle 50

Top Calle 50 Hotel Reviews

Aloft by Marriott Panama

Las Americas Golden Tower Panama

Courtyard by Marriott Panama Multiplaza Mall

Ramada Plaza by Wyndham Panama Punta Pacifica

Novotel Panama City

Renaissance Panama City Hotel

Hotel El Panama by Faranda Grand, a member of Radisson Individuals

Decapolis Hotel Panama City

Other attractions near Calle 50

Multiplaza Pacific Mall

Soho City Center

Avenida Balboa

Bingo 90

Pacific Center

National Shrine of the Heart of Mary

Multicentro Panama

Crown Casino

Frequently asked questions

Explore a world of travel with Expedia