Matlacha Isles Travel Guide
Cape Coral
Visit Matlacha Isles
Top hotels in Matlacha Isles
Marriott Sanibel Harbour Resort & Spa
17260 Harbour Pointe Dr Fort Myers FL
The price is 5.780.434 ₫ per night from 2 Nov to 3 Nov
5.780.434 ₫
7.351.614 ₫ total
2 Nov - 3 Nov
includes taxes & fees
Stay at this spa resort in Fort Myers. Enjoy 3 outdoor pools, a full-service spa and 4 restaurants. Our guests praise the helpful staff and the property condition ...
Margaritaville Beach Resort Fort Myers
251 Crescent Street Fort Myers Beach FL
The price is 4.638.332 ₫ per night from 21 Oct to 22 Oct
4.638.332 ₫
6.471.302 ₫ total
21 Oct - 22 Oct
includes taxes & fees
Stay at this beach hotel in Fort Myers Beach. Enjoy free Wi-Fi, a full-service spa and 4 restaurants. Our guests praise the pool and the helpful staff in their ...
9/10 Wonderful! (2,679 reviews)
"Very nice experience and service"
Reviewed on 19 Oct 2026
The Lighthouse Resort Inn & Suites
1051 5th St Fort Myers Beach FL
The price is 2.712.904 ₫ per night from 10 Nov to 11 Nov
2.712.904 ₫
3.542.588 ₫ total
10 Nov - 11 Nov
includes taxes & fees
Stay at this hotel in Fort Myers Beach. Enjoy free Wi-Fi, free parking and 2 outdoor pools. Our guests praise the pool and the helpful staff in their reviews. ...
Holiday Inn Express Cape Coral-Fort Myers Area by IHG
1538 Cape Coral Pkwy E Cape Coral FL
The price is 2.614.385 ₫ per night from 28 Oct to 29 Oct
2.614.385 ₫
2.915.039 ₫ total
28 Oct - 29 Oct
includes taxes & fees
Stay at this business-friendly hotel in Cape Coral. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the breakfast and the helpful staff ...
9.4/10 Exceptional! (1,714 reviews)
"jUST ok"
Reviewed on 19 Oct 2026
Lani Kai Beachfront Resort
1400 Estero Blvd Fort Myers Beach FL
The price is 3.704.143 ₫ per night from 21 Oct to 22 Oct
3.704.143 ₫
4.707.355 ₫ total
21 Oct - 22 Oct
includes taxes & fees
Stay at this beach hotel in Fort Myers Beach. Enjoy free Wi-Fi, 3 restaurants and a beach locale. Popular attractions Key West Express and Estero Boulevard Beach ...
8.8/10 Excellent! (2,129 reviews)
"Everything was wonderful."
Reviewed on 19 Oct 2026
Sanibel Island Beach Resort
1231 Middle Gulf Dr Sanibel FL
The price is 4.633.415 ₫ per night from 27 Oct to 28 Oct
4.633.415 ₫
5.887.933 ₫ total
27 Oct - 28 Oct
includes taxes & fees
Stay at this beach hotel in Sanibel. Enjoy free Wi-Fi, free parking and a beach locale. Our guests praise the pool and the restaurant in their reviews. Popular ...
9.2/10 Wonderful! (2,374 reviews)
"Need to have Sanibel map of sites in each room, an outdoor shower to clean off sand near tiki hut would be great! Loved toiletries. Bar is a little pricey 2 small bloody marys and one appitiser of onion rings = $50 plus tip. Your remodel is fantastic. You will see us again for a 5 day stay with more ..."
Reviewed on 19 Oct 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Where to stay in Matlacha Isles
Find the best Matlacha Isles areas for the activities you enjoy most.
Pelican
While visiting Pelican, you might make a stop by sights like Tarpon Point and Chabad Jewish Center.
Caloosahatchee
If you're spending some time in Caloosahatchee, Dolphin Marina and Cape Coral Yacht Club Beach are top sights worth seeing.
Hancock
While visiting Hancock, you might make a stop by sights like Four Mile Cove Ecological Preserve and Pine Island Shopping Center.
Yacht Club
While Yacht Club isn't home to many top sights, Cape Coral Yacht Club Beach and Dolphin Marina are some notable places to visit nearby.
Burnt Store
When in Burnt Store, you can plan a visit to Coral Oaks Golf Course and Burnt Store Marina, some noteworthy sights in the nearby area.
