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Our top choices for Matlacha Isles hotels

Lani Kai Beachfront Resort
Lani Kai Beachfront Resort23.2 km from Matlacha Isles
9.0 out of 10, Wonderful, (1,447 reviews)
The price is 4.453.319 ₫
5.553.078 ₫ total
includes taxes & fees
18 May - 19 May

The Bay Inn at Lani Kai
The Bay Inn at Lani Kai23.1 km from Matlacha Isles
7.6 out of 10, Good, (398 reviews)
The price is 3.059.351 ₫
3.998.804 ₫ total
includes taxes & fees
3 May - 4 May

HomeTowne Studios by Red Roof Fort Myers
HomeTowne Studios by Red Roof Fort Myers21.7 km from Matlacha Isles
The price is 1.778.321 ₫
1.982.828 ₫ total
includes taxes & fees
7 May - 8 May

Pointe Estero Beach Resort
Pointe Estero Beach Resort28.6 km from Matlacha Isles
9.2 out of 10, Wonderful, (1,000 reviews)
The price is 4.264.586 ₫
13.312.245 ₫ total
includes taxes & fees
6 May - 7 May

Comfort Suites Fort Myers East I-75
Comfort Suites Fort Myers East I-7524.8 km from Matlacha Isles
9.6 out of 10, Exceptional, (451 reviews)
The price is 2.337.334 ₫
2.606.127 ₫ total
includes taxes & fees
31 May - 1 Jun

1 Island Hideaway
1 Island Hideaway25.1 km from Matlacha Isles
8.6 out of 10, Excellent, (32 reviews)
The price is 5.243.451 ₫
11.693.159 ₫ total
includes taxes & fees
13 May - 14 May

StudioRes by Marriott Fort Myers Airport
StudioRes by Marriott Fort Myers Airport29.5 km from Matlacha Isles
9.4 out of 10, Exceptional, (48 reviews)
The price is 2.217.268 ₫
2.472.254 ₫ total
includes taxes & fees
12 May - 13 May

Boca Grande Hotel
Boca Grande Hotel28.8 km from Matlacha Isles
8.8 out of 10, Excellent, (630 reviews)
The price is 3.557.385 ₫
3.984.271 ₫ total
includes taxes & fees
3 May - 4 May

Park Motel
Park MotelDiplomat, 17.2 km from Matlacha Isles
9.2 out of 10, Wonderful, (46 reviews)
The price is 2.489.980 ₫
2.776.328 ₫ total
includes taxes & fees
9 May - 10 May

Holiday Inn Express & Suites Fort Myers Airport by IHG
Holiday Inn Express & Suites Fort Myers Airport by IHG29 km from Matlacha Isles
9.6 out of 10, Exceptional, (1,005 reviews)
The price is 2.602.688 ₫
2.902.035 ₫ total
includes taxes & fees
1 Jun - 2 Jun

Pink Shell Beach Resort and Marina
Pink Shell Beach Resort and Marina21.7 km from Matlacha Isles
9.4 out of 10, Exceptional, (1,337 reviews)
The price is 6.142.418 ₫
8.582.429 ₫ total
includes taxes & fees
20 May - 21 May

Best Western Plus Beach Resort
Best Western Plus Beach Resort22.4 km from Matlacha Isles
9.4 out of 10, Exceptional, (1,001 reviews)
The price is 7.313.193 ₫
8.154.210 ₫ total
includes taxes & fees
1 Jun - 2 Jun

Latitude 26 Waterfront Resort & Marina
Latitude 26 Waterfront Resort & Marina20.3 km from Matlacha Isles
8.6 out of 10, Excellent, (1,000 reviews)
The price is 2.666.519 ₫
2.973.169 ₫ total
includes taxes & fees
4 May - 5 May

Flamingo Inn
Flamingo Inn27.9 km from Matlacha Isles
7.8 out of 10, Good, (1,003 reviews)
The price is 2.239.665 ₫
4.226.870 ₫ total
includes taxes & fees
8 May - 9 May

Comfort Inn Fort Myers Northeast
Comfort Inn Fort Myers Northeast25.8 km from Matlacha Isles
7.8 out of 10, Good, (723 reviews)
The price is 1.957.616 ₫
2.182.742 ₫ total
includes taxes & fees
1 Jun - 2 Jun

Sanibel Island Beach Resort
Sanibel Island Beach Resort22.7 km from Matlacha Isles
9.2 out of 10, Wonderful, (1,843 reviews)
The price is 6.060.730 ₫
7.416.489 ₫ total
includes taxes & fees
17 May - 18 May

La Quinta Inn & Suites by Wyndham Ft. Myers-Sanibel Gateway
La Quinta Inn & Suites by Wyndham Ft. Myers-Sanibel Gateway18.3 km from Matlacha Isles
8.2 out of 10, Very good, (1,135 reviews)
The price is 1.981.595 ₫
2.209.479 ₫ total
includes taxes & fees
27 May - 28 May

Quality Suites Fort Myers I-75
Quality Suites Fort Myers I-7527.1 km from Matlacha Isles
8.4 out of 10, Very good, (1,001 reviews)
The price is 1.550.190 ₫
1.728.461 ₫ total
includes taxes & fees
17 May - 18 May

Extended Stay America Premier Suites - Fort Myers - Airport
Extended Stay America Premier Suites - Fort Myers - Airport23.6 km from Matlacha Isles
8.8 out of 10, Excellent, (962 reviews)
The price is 1.564.986 ₫
1.744.963 ₫ total
includes taxes & fees
3 May - 4 May

Americas Best Value Inn Ft. Myers
Americas Best Value Inn Ft. Myers19.3 km from Matlacha Isles
7.6 out of 10, Good, (1,235 reviews)
The price is 1.911.620 ₫
2.131.456 ₫ total
includes taxes & fees
5 May - 6 May
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Where to stay in Matlacha Isles
Find the best Matlacha Isles areas for the activities you enjoy most.

Pelican
While visiting Pelican, you might make a stop by sights like Tarpon Point and Tom Allen Memorial Butterfly Garden.

Caloosahatchee
If you're spending some time in Caloosahatchee, Cape Coral Yacht Club Beach and Dolphin Marina are top sights worth seeing.

Yacht Club
While Yacht Club isn't home to many top sights, Cape Coral Yacht Club Beach and Dolphin Marina are some notable places to visit nearby.

Hancock
While visiting Hancock, you might make a stop by sights like Four Mile Cove Ecological Preserve and Pine Island Shopping Center.
Burnt Store
When in Burnt Store, you can plan a visit to Coral Oaks Golf Course and Burnt Store Marina, some noteworthy sights in the nearby area.
Top Matlacha Isles Hotel Reviews

Days Inn & Suites by Wyndham Fort Myers Near JetBlue Park
10/10 Excellent

















































































