Matlacha Isles Holidays

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Where to stay in Matlacha Isles

Find the best Matlacha Isles areas and neighborhoods for the activities you enjoy most. Learn more about Matlacha Isles
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Pelican

1 out of top 10 points of interest in this area
4/5(1 area review)

While visiting Pelican, you might make a stop by sights like Tarpon Point and Harbour View Gallery.

Find hotels in Pelican

Top hotels in Matlacha Isles

Lani Kai Beachfront Resort

Lani Kai Beachfront Resort

3.5 out of 5
1400 Estero Blvd Fort Myers Beach FL
Fully refundableReserve now, pay when you stay
The price is 4.965.030 ₫ per night from 11 Jan to 12 Jan
4.965.030 ₫
6.121.829 ₫ total
11 Jan - 12 Jan
includes taxes & fees
9/10 Wonderful! (1,082 reviews)
It was our first time there. Would go back.

Reviewed on 6 Jan 2026

Lani Kai Beachfront Resort
Marriott Sanibel Harbour Resort & Spa

Marriott Sanibel Harbour Resort & Spa

4 out of 5
17260 Harbour Pointe Dr Fort Myers FL
Fully refundableReserve now, pay when you stay
The price is 9.430.930 ₫ per night from 10 Jan to 11 Jan
9.430.930 ₫
11.172.237 ₫ total
10 Jan - 11 Jan
includes taxes & fees
8.4/10 Very Good! (1,000 reviews)
Staff was very nice. A problem we had was their were 4 of us in the room and trying to get 4 towels and washcloths was a hard task, also coffee in room.

Reviewed on 3 Jan 2026

Marriott Sanibel Harbour Resort & Spa
Holiday Inn Express Cape Coral-Fort Myers Area by IHG

Holiday Inn Express Cape Coral-Fort Myers Area by IHG

2.5 out of 5
1538 Cape Coral Pkwy E Cape Coral FL
Fully refundable
The price is 3.730.340 ₫ per night from 11 Jan to 12 Jan
3.730.340 ₫
4.159.330 ₫ total
11 Jan - 12 Jan
includes taxes & fees
9.2/10 Wonderful! (1,140 reviews)
Privacy with own balcony, great breakfast every morning and friendly stuff.

Reviewed on 6 Jan 2026

Holiday Inn Express Cape Coral-Fort Myers Area by IHG
See all 14,347 properties in Matlacha Isles
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a Matlacha Isles holiday package cost?
Our Matlacha Isles holiday packages, which begin from just , are the best way to save loads of cash. Select your favourite flights, hotels and rental cars to create a custom-built itinerary.
How do I get a cheap travel package to Matlacha Isles?
Combine your hotel and flight bookings, add on extras such as activities, and save with a Matlacha Isles holiday package. You won't just walk away with awesome discounts on your trip — you'll have loads of choice at your fingertips too. When you book through Expedia, you'll have your pick of over 550 partner airlines and 1null000null000 hotels around the globe. Your next epic adventure begins right here, right now!
Where should I stay in Matlacha Isles?
If you're itching to be where the action is, stay near Sun Splash Water Park. Many happy campers book a hotel around this renowned tourist attraction.
What are the top hotels in Matlacha Isles?
Reserve a room at The Perfect Day In Matlacha Direct Gulf Access. It's one of the neighbourhood's most popular hotels. Another highly rated option in Matlacha Isles is Fun'n Sun - Charming 3 Br/ 3 Baths Waterfront Villa W. Boat Lift.
How far in advance should I book my Matlacha Isles holiday?
Smart travellers will likely want to reserve their seats early. You can normally start comparing international fares on Expedia up to a year before your intended flight. If you've left things to the last minute, don't stress. Low prices occasionally become available just weeks prior to departure.
What does an Expedia Matlacha Isles travel package include?
Expedia has all you need to organise your Matlacha Isles trip, but how you structure your package depends on you. Select from a combination of rental cars, hotels and flights. Chasing some experiences or tours to keep you busy? Once you've made your booking, you can add them on too. No matter your budget, there's a deal to suit your needs.
What should I know before booking a Matlacha Isles travel package?
Bundling your bookings into a Matlacha Isles holiday package is the easiest way to organise your trip. Not only that, you'll save just for combining your hotels, flights and car rentals. Once you've booked, why not add on a day tour or an activity?
Can I choose my airline with a Matlacha Isles Expedia holiday package?
Yes, definitely. Expedia has more than 550 partner airlines to select from globally. With all that choice, finding the ideal carrier to bring you to Matlacha Isles will be easy.
If I'm not able to travel, can I cancel my Matlacha Isles holiday package?
Don't worry if you're rethinking your Matlacha Isles holiday package — you can cancel or change your booking. And if you've booked it within 24 hours, you may be able to do it at no cost. However, bookings made more than 24 hours ago may incur charges from your airline, hotel or car rental company. We get that your circumstances can suddenly change, so look up our Customer Service Portal if that happens. When you're ready to make changes, we're ready to help.

Popular places to visit

Four Mile Cove Ecological Preserve

Four Mile Cove Ecological Preserve

Enjoy the beautiful sunsets and explore Four Mile Cove Ecological Preserve, a lovely green space in Cape Coral. Amble around this family-friendly area's beautiful beaches or attend a baseball game.

Four Mile Cove Ecological Preserve

Sun Splash Water Park

Enjoy a fun-filled day at Sun Splash Water Park during your visit to Cape Coral. Stroll along the beautiful beaches or discover the beautiful sunsets in this family-friendly area.

Sun Splash Water Park

Pine Island Shopping Center

You can browse for the perfect souvenirs at Pine Island Shopping Center during your stay in North Fort Myers. Stroll along the marina or attend a baseball game in this family-friendly area.

Pine Island Shopping Center