Search Hotels Near Center for Family Medicine, Sioux Falls

Start date: Check-in selected.
To Date
End date: Check-out

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
22 Dec - 23 Dec
Tomorrow
23 Dec - 24 Dec
This weekend
26 Dec - 28 Dec
Next weekend
2 Jan - 4 Jan

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Center for Family Medicine hotels

Interior detail
Hotel On Phillips

Hotel On Phillips

Hotel On Phillips
2.5 star property
Downtown Sioux Falls, 1.8 km from Center for Family Medicine
9.6 out of 10, Exceptional, (1304)
"Great staff and location!"
United States
Gerald
Hotel On Phillips
Terrace/patio
Home2 Suites By Hilton Sioux Falls/Sanford Medical Center

Home2 Suites By Hilton Sioux Falls/Sanford Medical Center

Home2 Suites By Hilton Sioux Falls/Sanford Medical Center
3.0 star property
University Heights, 2.4 km from Center for Family Medicine
9.4 out of 10, Exceptional, (585)
"This is a great hotel - centrally located and very clean and quiet. Will definitely be staying there again. "
United States
Tracey
The price is 2.654.131 ₫
2.964.211 ₫ total
includes taxes & fees
1 Jan - 2 Jan 2026
Home2 Suites By Hilton Sioux Falls/Sanford Medical Center
Meeting facility
Canopy By Hilton Sioux Falls Downtown

Canopy By Hilton Sioux Falls Downtown

Canopy By Hilton Sioux Falls Downtown
4.0 star property
Downtown Sioux Falls, 2.4 km from Center for Family Medicine
9.4 out of 10, Exceptional, (159)
"Room was very clean, great overall stay."
United States
Destiny
The price is 3.430.950 ₫
3.921.643 ₫ total
includes taxes & fees
1 Jan - 2 Jan 2026
Canopy By Hilton Sioux Falls Downtown
Meeting facility
Hilton Garden Inn Sioux Falls Downtown

Hilton Garden Inn Sioux Falls Downtown

Hilton Garden Inn Sioux Falls Downtown
3.0 star property
Downtown Sioux Falls, 1.8 km from Center for Family Medicine
8.8 out of 10, Excellent, (885)
"Friendly front desk staff, clean room, great location, safe "
United States
Hannah
The price is 2.737.755 ₫
3.161.209 ₫ total
includes taxes & fees
29 Dec - 30 Dec
Hilton Garden Inn Sioux Falls Downtown
Porch
Historic Victorian Inn

Historic Victorian Inn

Historic Victorian Inn
3.0 star property
Cathedral, 2.4 km from Center for Family Medicine
8.8 out of 10, Excellent, (56)
"It was a great place to stay and super interesting."
United States
Kathy
The price is 3.186.837 ₫
3.927.530 ₫ total
includes taxes & fees
26 Dec - 27 Dec
Historic Victorian Inn
Exterior
Holiday Inn Sioux Falls-City Centre by IHG

Holiday Inn Sioux Falls-City Centre by IHG

Holiday Inn Sioux Falls-City Centre by IHG
3.0 star property
Downtown Sioux Falls, 2 km from Center for Family Medicine
8.6 out of 10, Excellent, (1001)
"Always a great stay. "
United States
Shawn
The price is 2.710.445 ₫
3.025.989 ₫ total
includes taxes & fees
24 Dec - 25 Dec
Holiday Inn Sioux Falls-City Centre by IHG
Suite 2 Queens, Recliner, Pullout Sofa | Free WiFi, bed sheets
The Center Inn

The Center Inn

The Center Inn
2.5 star property
All Saints, 0.2 km from Center for Family Medicine
8.4 out of 10, Very good, (702)
"Room and staff were great. "
United States
Annette
The Center Inn
Exterior
Country Inn & Suites by Radisson, Sioux Falls, SD

Country Inn & Suites by Radisson, Sioux Falls, SD

Country Inn & Suites by Radisson, Sioux Falls, SD
3.0 star property
Downtown Sioux Falls, 1.9 km from Center for Family Medicine
8.4 out of 10, Very good, (1160)
"It was a great place to stay!"
United States
Trinity
The price is 2.302.522 ₫
2.578.496 ₫ total
includes taxes & fees
24 Dec - 25 Dec
Country Inn & Suites by Radisson, Sioux Falls, SD
Basic Studio, 1 King Bed | Desk, free WiFi, wheelchair access
Valley Inn

Valley Inn

Valley Inn
2.5 star property
University Heights, 2.4 km from Center for Family Medicine
7.8 out of 10, Good, (1000)
"Room was clean, staff was friendly, very convenient location "
United States
Theresa
Valley Inn
Lobby
Super 8 by Wyndham Sioux Falls

Super 8 by Wyndham Sioux Falls

Super 8 by Wyndham Sioux Falls
2.0 star property
2 km from Center for Family Medicine
7.4 out of 10, Good, (1002)
"Clean room and bath. Motel is well maintained and safe. Well-lit parking lot. Good place to stay. "
United States
Todd
The price is 1.815.735 ₫
2.044.676 ₫ total
includes taxes & fees
23 Dec - 24 Dec
Super 8 by Wyndham Sioux Falls
50-inch flat-screen TV with cable channels, fireplace, Netflix
Historic Twin Tudors Inn

Historic Twin Tudors Inn

Historic Twin Tudors Inn
3.0 star property
1.3 km from Center for Family Medicine
8.8 out of 10, Excellent, (3)
"Lovely place! Wish we could have stayed longer. Steve was attentive and helpful. "
United States
Anonymous traveller
The price is 7.081.366 ₫
8.030.092 ₫ total
includes taxes & fees
23 Dec - 24 Dec
Historic Twin Tudors Inn
Double Room | Desk, free WiFi
Settle Inn

Settle Inn

Settle Inn
3.0 star property
2.1 km from Center for Family Medicine
6.4 out of 10, (40)
"Rooms are very comfortable, convenient, clean, affordable, & what I love most is that it makes me feel like home."
United States
Janet
The price is 1.473.377 ₫
1.616.267 ₫ total
includes taxes & fees
23 Dec - 24 Dec
Settle Inn
Double Room, 2 Queen Beds | In-room safe, desk, laptop workspace, blackout curtains
Highpoint Hotel

Highpoint Hotel

Highpoint Hotel
3.0 star property
University Heights, 2.7 km from Center for Family Medicine
The price is 3.999.880 ₫
4.440.499 ₫ total
includes taxes & fees
12 Jan - 13 Jan 2026
Highpoint Hotel
Exterior detail
Clubhouse Hotel Suites Sioux Falls

Clubhouse Hotel Suites Sioux Falls

Clubhouse Hotel Suites Sioux Falls
3.0 star property
Mall District, 5.2 km from Center for Family Medicine
9.6 out of 10, Exceptional, (1004)
"Absolutely beautiful places to stay with family excellent service staff great food service great hospitality great "
United States
Rosario
Clubhouse Hotel Suites Sioux Falls
Exterior
Staybridge Suites Sioux Falls Southwest by IHG

Staybridge Suites Sioux Falls Southwest by IHG

Staybridge Suites Sioux Falls Southwest by IHG
3.0 star property
South Sioux Falls, 6.7 km from Center for Family Medicine
9.6 out of 10, Exceptional, (458)
"Staff was great, all very friendly. Room was very clean, and we had a great nights sleep. "
United States
Eric
The price is 2.368.350 ₫
2.650.709 ₫ total
includes taxes & fees
1 Jan - 2 Jan 2026
Staybridge Suites Sioux Falls Southwest by IHG
Indoor pool
Comfort Inn & Suites at Sanford Sports Complex

Comfort Inn & Suites at Sanford Sports Complex

Comfort Inn & Suites at Sanford Sports Complex
2.5 star property
Northwest Sioux Falls, 7.1 km from Center for Family Medicine
9.6 out of 10, Exceptional, (902)
"Perfect stay. This is what clean, quiet and convenient looks like at an affordable price. "
United States
Tiffany
The price is 2.486.504 ₫
2.780.325 ₫ total
includes taxes & fees
4 Jan - 5 Jan 2026
Comfort Inn & Suites at Sanford Sports Complex
Terrace/patio
Hyatt Place Sioux Falls South

Hyatt Place Sioux Falls South

Hyatt Place Sioux Falls South
3.0 star property
Mall District, 6.1 km from Center for Family Medicine
9.4 out of 10, Exceptional, (1002)
"Great stay!"
United States
Nick
The price is 3.078.855 ₫
3.430.133 ₫ total
includes taxes & fees
28 Dec - 29 Dec
Hyatt Place Sioux Falls South
Exterior
Holiday Inn & Suites Sioux Falls - Airport by IHG

Holiday Inn & Suites Sioux Falls - Airport by IHG

Holiday Inn & Suites Sioux Falls - Airport by IHG
3.0 star property
Northwest Sioux Falls, 4.9 km from Center for Family Medicine
9.2 out of 10, Wonderful, (844)
"Was the perfect place to stay for late arrival into airport. Nothing fancy but met expectations and there was a restaurant next door that you can walk to. "
United States
Joshua
The price is 2.605.185 ₫
2.910.702 ₫ total
includes taxes & fees
4 Jan - 5 Jan 2026
Holiday Inn & Suites Sioux Falls - Airport by IHG
Exterior
Hampton Inn Sioux Falls

Hampton Inn Sioux Falls

Hampton Inn Sioux Falls
2.5 star property
Mall District, 5.5 km from Center for Family Medicine
9.2 out of 10, Wonderful, (1007)
"It was a very nice stay. "
United States
Lenore
The price is 2.567.818 ₫
2.869.526 ₫ total
includes taxes & fees
2 Jan - 3 Jan 2026
Hampton Inn Sioux Falls
Lobby sitting area
Comfort Inn & Suites Avera Southwest

Comfort Inn & Suites Avera Southwest

Comfort Inn & Suites Avera Southwest
2.5 star property
South Sioux Falls, 6.8 km from Center for Family Medicine
9.4 out of 10, Exceptional, (1006)
"great location to stay."
United States
Tammy
The price is 2.781.496 ₫
3.103.933 ₫ total
includes taxes & fees
28 Dec - 29 Dec
Comfort Inn & Suites Avera Southwest
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top Center for Family Medicine Hotel Reviews

Settle Inn

Settle Inn

10/10 Excellent
"Nice"
Jamila 1-night trip
Posted 3 months ago
Settle Inn

Hotels near other Center for Family Medicine attractions

Old Courthouse Museum

You can spend time exploring the galleries in Old Courthouse Museum during your travels in Sioux Falls. Attend a sporting event or discover the area's beautiful waterfalls.
See properties

Michelangelo's David

You can learn about the history of Sioux Falls with a trip to Michelangelo's David. Attend a sporting event or discover the area's beautiful waterfalls.
See properties

Frequently asked questions

What's the area like around Center for Family Medicine?
Center for Family Medicine is located in Sioux Falls. This family-friendly area is known for its array of dining options and sporting events. If you're looking for a convenient place to stay, take a look at the 45 hotels and other accommodation options you'll find within a mile.
How many hotels can I expect to find near Center for Family Medicine?
Expedia has 45 hotels and other accommodation options within a mile from Center for Family Medicine.
If I need to cancel the hotel reservation for my stay near Center for Family Medicine, will I receive a refund?
Yes, the majority of hotel bookings are fully refundable provided that you cancel before the accommodation's cancellation deadline, which is usually within 24-48 hours of your arrival date. If your reservation is non-refundable, you may still be able to cancel and be given a refund within 24 hours of your booking. Enter dates in and click on "Search", then filter by "fully refundable" to review the best deals near Center for Family Medicine.
What can I see and do near Center for Family Medicine?
You'll want to browse the collections at Washington Pavilion of Arts and Science, Old Courthouse Museum and Center for Western Studies. Learn about local history at St. Joseph Cathedral and Pettigrew Home and Museum. Get outside and spend some time strolling around Falls Park, Fawick Park and Sherman Park.