A cityscape with a prominent modern skyscraper, historic buildings, and a well-maintained park with a jogging path.

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Next weekend
16 Oct - 18 Oct
In two weeks
23 Oct - 25 Oct

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Our top choices for Central Southwest hotels

A modern bedroom with a bed, a TV mounted on the wall, a door, and an air conditioning unit.

1. Crystal Suites

Crystal Suites
2.0 star property
Central Southwest
6.4 out of 10, (121 reviews)
"Perfect for what we needed it for Enjoy our stay every time we go "
United States
Theresa
The price is 1.681.680 ₫
1.967.566 ₫ total
includes taxes & fees
13 Oct - 14 Oct
Crystal Suites
A modern hotel room with a large bed, wooden flooring, a bedside telephone, and a mirror.

2. Blue Diamond Inn

Blue Diamond Inn
2.0 star property
Central Southwest
7.4 out of 10, Good, (13 reviews)
"The motel was okay. "
United States
George
The price is 1.979.208 ₫
2.315.673 ₫ total
includes taxes & fees
18 Oct - 19 Oct
Blue Diamond Inn
A neatly made bed with white linens, a wooden headboard, and a bedside table with a telephone.

3. Maxim III Motel

Maxim III Motel
2.5 star property
Central Southwest
7.4 out of 10, Good, (14 reviews)
"Room was nice and clean including the sheets, they had all the amenities. I would stay here again."
United States
Ebony
The price is 1.362.161 ₫
1.593.727 ₫ total
includes taxes & fees
13 Oct - 14 Oct
Maxim III Motel
A bedroom with a bed, dresser, desk, and a ceiling fan.

4. Sweet Home - Private BR in a Shared Home

Sweet Home - Private BR in a Shared Home
2.0 star property
Central Southwest
Sweet Home - Private BR in a Shared Home
A spacious dining area with multiple tables and chairs, large windows, and hanging pendant lights.

5. Holiday Inn Express & Suites Houston S - Medical Ctr Area by IHG

Holiday Inn Express & Suites Houston S - Medical Ctr Area by IHG
2.5 star property
6.1 km from Central Southwest
9.4 out of 10, Exceptional, (1,004 reviews)
"Very clean, friendly staff and great breakfast."
United States
Elisa
The price is 2.845.920 ₫
3.350.682 ₫ total
includes taxes & fees
18 Oct - 19 Oct
Holiday Inn Express & Suites Houston S - Medical Ctr Area by IHG
A reception area with a wooden reception desk, two refrigerators, and clocks displaying different city names.

6. Best Western Plus Pearland/Houston Medical Center Hotel

Best Western Plus Pearland/Houston Medical Center Hotel
2.5 star property
Southeast Houston, 8.4 km from Central Southwest
9.4 out of 10, Exceptional, (458 reviews)
"Happy to stayed there!"
United States
AYTUNC
The price is 2.305.454 ₫
2.697.381 ₫ total
includes taxes & fees
14 Oct - 15 Oct
Best Western Plus Pearland/Houston Medical Center Hotel
A spacious hotel lobby with high ceilings, large windows, a long bar area, and a seating area with a sofa and chairs.

7. Hyatt Place Houston Medical Center

Hyatt Place Houston Medical Center
3.0 star property
Texas Medical Center, 8 km from Central Southwest
9.2 out of 10, Wonderful, (2,695 reviews)
"Great stay!"
United States
Anthony
The price is 3.285.744 ₫
3.864.694 ₫ total
includes taxes & fees
26 Oct - 27 Oct
Hyatt Place Houston Medical Center
A rooftop patio with outdoor seating, fire pits, and a view of the cityscape.

8. Hilton Houston Plaza/Medical Center

Hilton Houston Plaza/Medical Center
4.5 star property
Texas Medical Center, 9.3 km from Central Southwest
8.4 out of 10, Very good, (2,197 reviews)
"Room was great, staff was helpful"
United States
Marvin
The price is 2.836.865 ₫
3.349.143 ₫ total
includes taxes & fees
18 Oct - 19 Oct
Hilton Houston Plaza/Medical Center
A modern interior with a vertical garden wall and a sign reading "ESPERANTO".

9. Hotel Ylem

Hotel Ylem
3.5 star property
7.2 km from Central Southwest
8.4 out of 10, Very good, (1,580 reviews)
"clean hotel, very nice I enjoyed my stay!"
United States
aundrea
The price is 1.799.407 ₫
2.234.665 ₫ total
includes taxes & fees
28 Oct - 29 Oct
Hotel Ylem
A spacious hotel lobby with high ceilings, large windows, a long bar area, and a seating area with a sofa and chairs.

10. Hyatt House Houston Medical Center

Hyatt House Houston Medical Center
3.0 star property
Texas Medical Center, 8 km from Central Southwest
9.2 out of 10, Wonderful, (1,282 reviews)
"Great location and the bed was amazingly comfortable!!"
United States
Debra
The price is 3.268.494 ₫
3.844.406 ₫ total
includes taxes & fees
26 Oct - 27 Oct
Hyatt House Houston Medical Center
A hotel lobby with a seating area, a reception desk, and a staircase.

11. Heritage Inn Suites Houston/Sugar Land, Trademark by Wyndham

Heritage Inn Suites Houston/Sugar Land, Trademark by Wyndham
3.0 star property
16.4 km from Central Southwest
8.8 out of 10, Excellent, (1,408 reviews)
"The facility is well organized and the staff’s were very helpful."
United States
Dearmar
The price is 2.177.129 ₫
2.503.698 ₫ total
includes taxes & fees
13 Oct - 14 Oct
Heritage Inn Suites Houston/Sugar Land, Trademark by Wyndham
A bar area with a long counter, bar stools, a refrigerated display case with beverages, and a menu board above the counter.

12. Courtyard By Marriott Houston Medical Center Reliant Park

Courtyard By Marriott Houston Medical Center Reliant Park
3.0 star property
7.6 km from Central Southwest
8.6 out of 10, Excellent, (1,002 reviews)
"Great Hotel!"
United States
Jorge
The price is 3.120.163 ₫
3.688.629 ₫ total
includes taxes & fees
18 Oct - 19 Oct
Courtyard By Marriott Houston Medical Center Reliant Park
An indoor dining area with tables and chairs, a central fountain, and a stone wall with a lion sculpture.

13. Doubletree by Hilton Houston Hobby Airport

Doubletree by Hilton Houston Hobby Airport
4.0 star property
Southeast Houston, 16.2 km from Central Southwest
8.8 out of 10, Excellent, (1,002 reviews)
"close to airport and dining"
United States
Amelia
The price is 2.506.997 ₫
2.961.645 ₫ total
includes taxes & fees
18 Oct - 19 Oct
Doubletree by Hilton Houston Hobby Airport
A hotel room with a large bathtub, a bed with white bedding, a wooden headboard, and a nightstand with a lamp.

14. Comfort Suites Houston near Medical Center- NRG Stadium

Comfort Suites Houston near Medical Center- NRG Stadium
2.5 star property
6.8 km from Central Southwest
8.8 out of 10, Excellent, (1,000 reviews)
"Clean rooms and staff is great."
United States
Tamy
The price is 2.069.760 ₫
2.421.620 ₫ total
includes taxes & fees
1 Nov - 2 Nov
Comfort Suites Houston near Medical Center- NRG Stadium
A modern breakfast area with labeled sections for yogurt, eggs, and milk, and a sign indicating the direction to the restrooms.

15. Holiday Inn Express & Suites Stafford NW - Sugar Land by IHG

Holiday Inn Express & Suites Stafford NW - Sugar Land by IHG
2.5 star property
14.4 km from Central Southwest
9.4 out of 10, Exceptional, (704 reviews)
"Comfortable stay, friendly staff and amenities are great."
United States
Jessica Monica
The price is 2.173.248 ₫
2.499.235 ₫ total
includes taxes & fees
22 Oct - 23 Oct
Holiday Inn Express & Suites Stafford NW - Sugar Land by IHG
A spacious room with large windows, a red armchair, a small table, and a cabinet with decorative items.

16. Studio 6 Houston, TX – Pearland/Medical Center

Studio 6 Houston, TX – Pearland/Medical Center
2.0 star property
Southeast Houston, 12.1 km from Central Southwest
9.2 out of 10, Wonderful, (258 reviews)
"Very clean rooms and nice staff"
United States
Mariesha
The price is 1.552.320 ₫
1.816.214 ₫ total
includes taxes & fees
13 Oct - 14 Oct
Studio 6 Houston, TX – Pearland/Medical Center
A modern hotel room with a large bed, bedside tables, a desk, and a chair.

17. Best Western Plus Sugar Land/Stafford

Best Western Plus Sugar Land/Stafford
2.5 star property
16.8 km from Central Southwest
9.0 out of 10, Wonderful, (1,009 reviews)
"Great hotel staff and amenities"
United States
Henry
The price is 2.162.640 ₫
2.487.035 ₫ total
includes taxes & fees
18 Oct - 19 Oct
Best Western Plus Sugar Land/Stafford
An outdoor patio with round tables and chairs, a brick wall, and a view of a body of water and trees at dusk.

18. Hyatt Place Houston/Sugar Land

Hyatt Place Houston/Sugar Land
3.0 star property
18.8 km from Central Southwest
9.0 out of 10, Wonderful, (1,960 reviews)
"Great location and staff"
United States
Daniel
The price is 2.836.865 ₫
3.262.395 ₫ total
includes taxes & fees
18 Oct - 19 Oct
Hyatt Place Houston/Sugar Land
A modern hotel interior with a central spiral staircase, large glass windows, and a buffet area with various food items.

19. The Royal Sonesta Houston Galleria

The Royal Sonesta Houston Galleria
4.0 star property
The Galleria, 12.9 km from Central Southwest
8.8 out of 10, Excellent, (2,310 reviews)
"Enjoyed our stay"
United States
Thomas
The price is 3.336.618 ₫
3.903.914 ₫ total
includes taxes & fees
24 Oct - 25 Oct
The Royal Sonesta Houston Galleria
A rooftop pool area with lounge chairs and a view of a tall building at night.

20. The Westin Houston Medical Center/Museum District

The Westin Houston Medical Center/Museum District
4.0 star property
Texas Medical Center, 9.3 km from Central Southwest
9.2 out of 10, Wonderful, (1,248 reviews)
"Great place"
United States
Matthew
The price is 4.156.337 ₫
5.173.393 ₫ total
includes taxes & fees
25 Oct - 26 Oct
The Westin Houston Medical Center/Museum District
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Hotels recommended for families in Central Southwest

A spacious dining area with multiple tables and chairs, large windows, and hanging pendant lights.

Holiday Inn Express & Suites Houston S - Medical Ctr Area by IHG

Holiday Inn Express & Suites Houston S - Medical Ctr Area by IHG
2.5 star property
Braeswood Place
9.4 out of 10, Exceptional, (1,004)
The price is 2.845.920 ₫
3.350.682 ₫ total
includes taxes & fees
18 Oct - 19 Oct
Holiday Inn Express & Suites Houston S - Medical Ctr Area by IHG

Where to stay in Central Southwest

Find the best Central Southwest areas for the activities you enjoy most.
A bridge with the words "Welcome to Downtown Houston" and a star emblem.

Downtown Houston

Gourmet restaurants acclaimed theatres and top sights from Daikin Park to Toyota Center – discover Downtown Houston, a destination also famous for its sports teams.

A tall, modern building with a unique, vertical design, surrounded by trees and a partly cloudy sky.

The Galleria

Travellers to The Galleria praise its popular shops. If you've got some more time to explore, be sure to stop by The Galleria and Williams Tower.

A cityscape with dense high-rise buildings, a river, and surrounding greenery.

Texas Medical Center

Well liked for its restaurants, museums and shopping, there's plenty to explore in Texas Medical Center. Attractions like Houston Zoo are a major draw, and you can hop on the metro at TMC Transit Center or Dryden/TMC Station to see more of the city.

A city skyline with modern skyscrapers and a river flowing through a park.

Montrose

Unique features of Montrose include the theatres and museums. Make a stop by Rothko Chapel or Menil Collection while you're exploring the area.

A modern cityscape with a tram and tall buildings.
Photo by George Zimzores
Open Photo by George Zimzores

Houston Central Business District

If you're spending time in Houston Central Business District, check out sights like Toyota Center or House of Blues Houston and hop on the metro to see more of the city at Bell Station or Downtown Transit Center Station.

Top Central Southwest Hotel Reviews

The Westin Houston Medical Center/Museum District

The Westin Houston Medical Center/Museum District

10/10 Excellent
"Clean and Close to attractions"
Tamika 2-night trip
Posted less than an hour ago
The Westin Houston Medical Center/Museum District

Frequently asked questions

What is Central Southwest like?
You'll be sure to have fun exploring Houston's Central Southwest neighbourhood. Make sure that you visit Wildcat Golf Club and Houston Sports Park as part of your Central Southwest travel plans.
How many hotels will I find in Central Southwest?
If you're searching for places to stay in Houston, Expedia has something to meet your needs with 74 Central Southwest hotels and other accommodation options to choose from.
If I need to cancel my hotel reservation in Central Southwest, will I receive a refund?
Yes, you'll find most hotel bookings are fully refundable if cancelled prior to the accommodation's cancellation deadline, which is usually within 24-48 hours of the scheduled arrival. If you have a reservation that's non-refundable, you may still be able to cancel and get a refund within 24 hours of your booking. Add your dates and click on "Search", then you can use the "fully refundable" filter to view top deals in Central Southwest.
What can I see and do in this Houston neighbourhood?
Spend some time exploring the natural setting of Central Southwest with a visit to Houston Sports Park and Eclectic Menagerie Park. Wildcat Golf Club and Aveva Stadium are also a couple of places to visit in the neighbourhood. A few places to visit in the area around Central Southwest include American Cowboy Museum, The Collective: Grand Ballroom and Garibaldi Sport Arena. When you're sightseeing around the area, Reliant Stadium and NRG Arena are a couple of other sights to visit.