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Our top choices for Del Rio hotels

Free daily buffet breakfast
Tru By Hilton St. Augustine I-95

Tru By Hilton St. Augustine I-95

Tru By Hilton St. Augustine I-95
2.5 star property
29.5 km from Del Rio
9.2 out of 10, Wonderful, (98)
"Great stay, breakfast was included "
United States
Sandra
The price is 2.569.379 ₫
2.864.857 ₫ total
includes taxes & fees
4 Jan - 5 Jan 2026
Tru By Hilton St. Augustine I-95
Exterior
Hyatt Regency Jacksonville

Hyatt Regency Jacksonville

Hyatt Regency Jacksonville
4.0 star property
Downtown Jacksonville, 21.5 km from Del Rio
9.0 out of 10, Wonderful, (1408)
"Great stay "
United States
terria
The price is 3.896.988 ₫
4.467.312 ₫ total
includes taxes & fees
1 Jan - 2 Jan 2026
Hyatt Regency Jacksonville
Sports facility
Hyatt Place Jacksonville / St. Johns Town Center

Hyatt Place Jacksonville / St. Johns Town Center

Hyatt Place Jacksonville / St. Johns Town Center
3.0 star property
Southside, 13.6 km from Del Rio
9.2 out of 10, Wonderful, (1007)
"Quiet, near a lot of restaurants and shopping and all within walking distance. Staff was very friendly."
United States
Amber
The price is 3.243.979 ₫
3.681.916 ₫ total
includes taxes & fees
29 Dec - 30 Dec
Hyatt Place Jacksonville / St. Johns Town Center
Room, 1 King Bed, Non Smoking | Premium bedding, desk, laptop workspace, iron/ironing board
La Quinta Inn & Suites by Wyndham St. Augustine

La Quinta Inn & Suites by Wyndham St. Augustine

La Quinta Inn & Suites by Wyndham St. Augustine
3.0 star property
29.8 km from Del Rio
7.8 out of 10, Good, (1412)
"Stayed for one night, room was very clean and staff were super friendly "
United States
Madylin
The price is 1.723.495 ₫
1.921.697 ₫ total
includes taxes & fees
11 Jan - 12 Jan 2026
La Quinta Inn & Suites by Wyndham St. Augustine
Free daily buffet breakfast
Hampton Inn & Suites Jacksonville South - Bartram Park

Hampton Inn & Suites Jacksonville South - Bartram Park

Hampton Inn & Suites Jacksonville South - Bartram Park
3.0 star property
3.3 km from Del Rio
9.0 out of 10, Wonderful, (1000)
"The staff was very friendly and helpful. "
United States
Carmelle
The price is 2.353.644 ₫
2.671.386 ₫ total
includes taxes & fees
3 Jan - 4 Jan 2026
Hampton Inn & Suites Jacksonville South - Bartram Park
Outdoor spa tub
The Smart Stay Inn

The Smart Stay Inn

The Smart Stay Inn
2.5 star property
29.8 km from Del Rio
8.6 out of 10, Excellent, (1853)
"Great place loved the hot tub"
United States
Shilo Ann
The price is 2.606.769 ₫
2.906.547 ₫ total
includes taxes & fees
7 Jan - 8 Jan 2026
The Smart Stay Inn
Blackout curtains, iron/ironing board, free cots/infant beds
Days Inn by Wyndham St. Augustine I-95/Outlet Mall

Days Inn by Wyndham St. Augustine I-95/Outlet Mall

Days Inn by Wyndham St. Augustine I-95/Outlet Mall
2.0 star property
29.3 km from Del Rio
7.2 out of 10, Good, (1006)
"Clean room, staff was helpful, good parking, good access, good location."
United States
Ron
The price is 1.382.641 ₫
1.541.645 ₫ total
includes taxes & fees
13 Jan - 14 Jan 2026
Days Inn by Wyndham St. Augustine I-95/Outlet Mall
Lobby
Margaritaville Jacksonville Beach

Margaritaville Jacksonville Beach

Margaritaville Jacksonville Beach
2.5 star property
24.9 km from Del Rio
9.0 out of 10, Wonderful, (3453)
"Nice stay!"
United States
Mark
The price is 3.530.987 ₫
4.007.669 ₫ total
includes taxes & fees
4 Jan - 5 Jan 2026
Margaritaville Jacksonville Beach
Breakfast and dinner served, American cuisine
Courtyard by Marriott St Augustine I-95

Courtyard by Marriott St Augustine I-95

Courtyard by Marriott St Augustine I-95
3.0 star property
30.7 km from Del Rio
8.6 out of 10, Excellent, (1000)
"Excellent "
United States
Wayne
The price is 2.106.480 ₫
2.348.725 ₫ total
includes taxes & fees
4 Jan - 5 Jan 2026
Courtyard by Marriott St Augustine I-95
Balcony
One Ocean Resort and Spa

One Ocean Resort and Spa

One Ocean Resort and Spa
4.5 star property
26.9 km from Del Rio
8.8 out of 10, Excellent, (1004)
"Clean rooms and very nice staff "
United States
Arthur
The price is 4.194.832 ₫
5.610.309 ₫ total
includes taxes & fees
12 Jan - 13 Jan 2026
One Ocean Resort and Spa
Lobby
Hilton Garden Inn Jacksonville Ponte Vedra Sawgrass

Hilton Garden Inn Jacksonville Ponte Vedra Sawgrass

Hilton Garden Inn Jacksonville Ponte Vedra Sawgrass
3.0 star property
20 km from Del Rio
9.0 out of 10, Wonderful, (1005)
"Friendly staff, easy check-in super clean room and facility. Location is excellent as well."
United States
Anthony
The price is 3.041.231 ₫
3.390.973 ₫ total
includes taxes & fees
4 Jan - 5 Jan 2026
Hilton Garden Inn Jacksonville Ponte Vedra Sawgrass
Property amenity
Sheraton Jacksonville Hotel

Sheraton Jacksonville Hotel

Sheraton Jacksonville Hotel
4.0 star property
Deerwood, 12.4 km from Del Rio
9.2 out of 10, Wonderful, (1001)
"Great stay and great customer service"
United States
Rebecca
The price is 2.444.229 ₫
2.774.200 ₫ total
includes taxes & fees
28 Dec - 29 Dec
Sheraton Jacksonville Hotel
Reception
Holiday Inn Express Hotel & Suites Saint Augustine North by IHG

Holiday Inn Express Hotel & Suites Saint Augustine North by IHG

Holiday Inn Express Hotel & Suites Saint Augustine North by IHG
2.5 star property
30.1 km from Del Rio
7.8 out of 10, Good, (1007)
"Very nice hotel, clean , good location, staff so friendly "
United States
Ana
The price is 1.948.642 ₫
2.251.735 ₫ total
includes taxes & fees
11 Jan - 12 Jan 2026
Holiday Inn Express Hotel & Suites Saint Augustine North by IHG
Exterior
Seahorse Oceanfront Inn

Seahorse Oceanfront Inn

Seahorse Oceanfront Inn
2.5 star property
26.9 km from Del Rio
9.0 out of 10, Wonderful, (609)
"Room was clean staff was friendly"
United States
Lisa
Seahorse Oceanfront Inn
Exterior
Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area

Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area

Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area
2.5 star property
21.5 km from Del Rio
9.0 out of 10, Wonderful, (1010)
"Good location for exploring Ponte Vedra and Jacksonville Beach areas."
United States
Julianne
The price is 3.109.401 ₫
3.529.170 ₫ total
includes taxes & fees
30 Dec - 31 Dec
Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area
Breakfast, lunch, dinner served; American cuisine
Hilton Jacksonville At Mayo Clinic

Hilton Jacksonville At Mayo Clinic

Hilton Jacksonville At Mayo Clinic
4.5 star property
18.3 km from Del Rio
9.4 out of 10, Exceptional, (77)
"Great place to stay"
United States
Judy
The price is 3.411.703 ₫
3.872.284 ₫ total
includes taxes & fees
30 Dec - 31 Dec
Hilton Jacksonville At Mayo Clinic
Free daily continental breakfast
TownePlace Suites by Marriott Middleburg

TownePlace Suites by Marriott Middleburg

TownePlace Suites by Marriott Middleburg
2.5 star property
24.3 km from Del Rio
10.0 out of 10, Exceptional, (27)
"Friendly staff Clean room Nice workout room Great breakfast"
United States
Robin
The price is 3.265.044 ₫
3.673.175 ₫ total
includes taxes & fees
4 Jan - 5 Jan 2026
TownePlace Suites by Marriott Middleburg
Exterior
Tru by Hilton Jacksonville South Mandarin

Tru by Hilton Jacksonville South Mandarin

Tru by Hilton Jacksonville South Mandarin
2.5 star property
6.8 km from Del Rio
9.0 out of 10, Wonderful, (1009)
"Excellent staff and hotel "
United States
Edward
The price is 2.353.465 ₫
2.671.184 ₫ total
includes taxes & fees
4 Jan - 5 Jan 2026
Tru by Hilton Jacksonville South Mandarin
Lobby lounge
Courtyard by Marriott Jacksonville Flagler Center

Courtyard by Marriott Jacksonville Flagler Center

Courtyard by Marriott Jacksonville Flagler Center
3.0 star property
4.2 km from Del Rio
8.8 out of 10, Excellent, (1000)
"Great hotel "
United States
Sandra
The price is 2.527.968 ₫
2.869.244 ₫ total
includes taxes & fees
28 Dec - 29 Dec
Courtyard by Marriott Jacksonville Flagler Center
Terrace/patio
Home2 Suites by Hilton St. Augustine I-95

Home2 Suites by Hilton St. Augustine I-95

Home2 Suites by Hilton St. Augustine I-95
3.0 star property
29.7 km from Del Rio
8.8 out of 10, Excellent, (1007)
"Room was great, staff very friendly, breakfast was great!"
United States
Cathy
The price is 3.334.821 ₫
3.718.325 ₫ total
includes taxes & fees
4 Jan - 5 Jan 2026
Home2 Suites by Hilton St. Augustine I-95
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Where to stay in Del Rio

Find the best Del Rio areas for the activities you enjoy most.
Photo by Ryan Ketterman
Open Photo by Ryan Ketterman

Downtown Jacksonville

Florida Theatre and Jacksonville Museum of Modern Art are top sights in Downtown Jacksonville, and you should be sure to explore the stunning river views. Hop aboard the metro at Riverplace Station or Kings Avenue Station to see more sights in the area.

Amelia City

While visiting Amelia City, you might make a stop by sights like American Beach and Fernandina Beach.

Southside

If you're spending some time in Southside, St. Johns Town Center and Orange Park Place Shopping Center are top sights worth seeing.

Sawgrass

Beaches and riverfront are just a few things travellers like about Sawgrass. A stop by Mickler Beach is also recommended if you've got time to explore the area.

Cummer Museum of Art and Gardens featuring art and interior views as well as a couple
Photo by Visit Jacksonville
Open Photo by Visit Jacksonville

Northwest

While visiting Northwest, you might make a stop by sights like Cummer Museum of Art and Gardens and Jacksonville-Baldwin Rail Trail.

Top Del Rio Hotel Reviews

Hilton Jacksonville At Mayo Clinic

Hilton Jacksonville At Mayo Clinic

10/10 Excellent
"The hotel is brand new. The design, finishes, and colors are well chosen. The hotel is on the Mayo campus, and the Mayo shuttle comes every 15 minutes. The restaurant located at the hotel was fantastic, the food was delicious and well prepared. All the employees at the hotel were very polite, helpful, and obviously invested in making that Hilton stand out. I really enjoyed my stay there."
Marc 1-night trip
Posted 6 days ago
Hilton Jacksonville At Mayo Clinic

Frequently asked questions

What is Del Rio like?
Travellers to Jacksonville's Del Rio neighbourhood will be sure to enjoy a stay here.
How many hotels can I expect to find in the Del Rio area?
Expedia has 8 Del Rio hotels and other accommodation options, and one might make a good home base for venturing out into the greater Jacksonville area.
If I need to cancel my hotel reservation in Del Rio, will I receive a refund?
Yes, the majority of room reservations are fully refundable as long as you cancel before the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of your check-in date. If you have a reservation that's non-refundable, you might be able to still cancel and get a refund within a 24-hour period of booking. Enter dates in and click on "Search", then you can use the "fully refundable" filter to view the best deals in Del Rio.
What can I see and do in this Jacksonville neighbourhood?
Places you might want to visit in the area around Del Rio include The Champions Club at Julington Creek and Latitude 30. When you're sightseeing around the area, The Avenues and Bowlero Mandarin are a couple of other sights to visit.