Downtown Holidays
Book a Hotel + Flight or Car together to unlock savings
Where to stay in Downtown
Find the best Downtown areas and neighborhoods for the activities you enjoy most. Learn more about Downtown
Serenity Bay
When in Serenity Bay, you can plan a visit to Keowee Key Golf Course and Lake Keowee, some noteworthy sights in the nearby area.
Top hotels in Downtown
Quality Inn Seneca Clemson Area US-123
226 Hi Tech Rd Seneca SC
Fully refundable
The price is 2.100.176 ₫ per night from 28 Jun to 29 Jun
2.100.176 ₫
2.472.049 ₫ total
28 Jun - 29 Jun
includes taxes & fees
8/10 Very Good! (719 reviews)
"By far the cleanest hotel I have ever stayed in."
Reviewed on 20 Jun 2026
Days Inn by Wyndham Anderson
1007 George Smith Mill Rd Anderson SC
Fully refundableReserve now, pay when you stay
The price is 1.543.551 ₫ per night from 8 Jul to 9 Jul
1.543.551 ₫
1.713.340 ₫ total
8 Jul - 9 Jul
includes taxes & fees
8/10 Very Good! (1,003 reviews)
"Staff was friendly, the first room had flies everywhere, so I had to get another room from the lady at the front desk, she gave us another room which was smelling good , and had everything from the previous room! Nice area , plus jockey flea market is very nice and just around the corner!"
Reviewed on 19 Jun 2026
The Shepherd Hotel Downtown Clemson
110 Sloan St Clemson SC
Fully refundableReserve now, pay when you stay
The price is 4.002.968 ₫ per night from 29 Jun to 30 Jun
4.002.968 ₫
4.443.268 ₫ total
29 Jun - 30 Jun
includes taxes & fees
9.8/10 Exceptional! (819 reviews)
"Trip to visit Clemson University campus. Room was beautifully appointed, average size but comfortable. Lobby is gorgeous, southern organic. Restaurant on site great for breakfast and dinner. Employees were calm, friendly and made on feel at home. A nice bar with an indoor area and terrace too."
Reviewed on 20 Jun 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.